Pathway: CXCL

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Secreted Signaling

Details on the CXCL pathway:

Specificity Index HSPC as target: 0.556
HSPC as source: 0.473

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the CXCL pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target CXCL Target ESAM ESAM Cell-Cell Contact 0.1005 0.0245545179168947 Scatter Plot
Target CXCL Source ESAM ESAM Cell-Cell Contact 0.1005 0.0245545179168947 Scatter Plot
Target CXCL Source PROS PROS Secreted Signaling 0.1022 0.0222784987394877 Scatter Plot
Target CXCL Source ANGPTL ANGPTL Secreted Signaling 0.1023 0.0220905148075773 Scatter Plot
Source CXCL Source AGRN AGRN ECM-Receptor 0.1028 0.0215074879827788 Scatter Plot
Target CXCL Target BST2 BST2 Cell-Cell Contact 0.1032 0.0210290097708253 Scatter Plot
Target CXCL Source CD34 CD34 Cell-Cell Contact 0.1046 0.019346593673872 Scatter Plot
Target CXCL Source JAM JAM Cell-Cell Contact 0.1050 0.0188981437086998 Scatter Plot
Target CXCL Source FN1 FN1 ECM-Receptor 0.1059 0.0178204457914465 Scatter Plot
Target CXCL Source PTN PTN Secreted Signaling 0.1082 0.0154628872610709 Scatter Plot
Target CXCL Target SELE SELE Cell-Cell Contact 0.1119 0.0122881003602278 Scatter Plot
Source CXCL Source PECAM1 PECAM1 Cell-Cell Contact 0.1131 0.0113630168529294 Scatter Plot
Target CXCL Target ANGPTL ANGPTL Secreted Signaling 0.1155 0.0097407822785653 Scatter Plot
Source CXCL Source WNT WNT Secreted Signaling 0.1174 0.0086143893420788 Scatter Plot
Target CXCL Target IGF IGF Secreted Signaling 0.1198 0.0073181685177038 Scatter Plot
Target CXCL Source VISFATIN VISFATIN Secreted Signaling 0.1199 0.0072646244211278 Scatter Plot
Target CXCL Target TENASCIN TENASCIN ECM-Receptor 0.1230 0.0058781508155736 Scatter Plot
Target CXCL Target AGT AGT Secreted Signaling 0.1252 0.0050510663557856 Scatter Plot
Target CXCL Source FLT3 FLT3 Secreted Signaling 0.1354 0.0024107130601603 Scatter Plot
Target CXCL Source MIF MIF Secreted Signaling 0.1376 0.0020445982967245 Scatter Plot
Source CXCL Source APELIN APELIN Secreted Signaling 0.1395 0.0017689583540723 Scatter Plot
Target CXCL Source IL1 IL1 Secreted Signaling 0.1401 0.0016873443755974 Scatter Plot
Target CXCL Source NT NT Secreted Signaling 0.1409 0.0015888675088053 Scatter Plot
Target CXCL Source TGFb TGFb Secreted Signaling 0.1433 0.0013127776011211 Scatter Plot
Target CXCL Target CD34 CD34 Cell-Cell Contact 0.1446 0.0011843730637613 Scatter Plot
Source CXCL Source CADM CADM Cell-Cell Contact 0.1459 0.0010702938221305 Scatter Plot
Source CXCL Source IL6 IL6 Secreted Signaling 0.1503 0.0007474958335967 Scatter Plot
Source CXCL Source THBS THBS ECM-Receptor 0.1518 0.000661014079052 Scatter Plot
Target CXCL Target VWF VWF ECM-Receptor 0.1556 0.0004777141566436 Scatter Plot
Source CXCL Source SEMA6 SEMA6 Cell-Cell Contact 0.1559 0.0004656143602699 Scatter Plot
Source CXCL Source NOTCH NOTCH Cell-Cell Contact 0.1568 0.0004329718024743 Scatter Plot
Target CXCL Source GRN GRN Secreted Signaling 0.1575 0.0004059743610869 Scatter Plot
Target CXCL Target COMPLEMENT COMPLEMENT Secreted Signaling 0.1604 0.0003167957674451 Scatter Plot
Target CXCL Target COLLAGEN COLLAGEN ECM-Receptor 0.1611 0.0002991559566689 Scatter Plot
Target CXCL Source NCAM NCAM Cell-Cell Contact 0.1621 0.0002738112052197 Scatter Plot
Source CXCL Source CD46 CD46 Cell-Cell Contact 0.1679 0.0001621342023292 Scatter Plot
Source CXCL Source SEMA3 SEMA3 Secreted Signaling 0.1712 0.0001198277589967 Scatter Plot
Target CXCL Source SELPLG SELPLG Cell-Cell Contact 0.1726 0.0001048382786482 Scatter Plot
Target CXCL Source PDGF PDGF Secreted Signaling 0.1733 0.00009818661201894142 Scatter Plot
Target CXCL Source BAFF BAFF Secreted Signaling 0.1806 0.000048477591209000935 Scatter Plot
Source CXCL Source CD39 CD39 Cell-Cell Contact 0.1829 0.00003889355072125187 Scatter Plot
Source CXCL Source PTN PTN Secreted Signaling 0.1841 0.000034378291688363616 Scatter Plot
Target CXCL Source CLEC CLEC Cell-Cell Contact 0.1913 0.000016635826649292152 Scatter Plot
Source CXCL Source GP1BA GP1BA Cell-Cell Contact 0.1964 0.00000966838958890339 Scatter Plot
Source CXCL Source CD1D2 CD1D2 Cell-Cell Contact 0.1988 0.00000750907781405996 Scatter Plot
Source CXCL Source ANGPTL ANGPTL Secreted Signaling 0.2062 0.0000033115981339848326 Scatter Plot
Target CXCL Source LAIR1 LAIR1 Cell-Cell Contact 0.2124 0.0000016493280263869226 Scatter Plot
Source CXCL Source CCL CCL Secreted Signaling 0.2147 0.0000012604188119464454 Scatter Plot
Source CXCL Source GDF GDF Secreted Signaling 0.2193 0.0000007337128175413596 Scatter Plot
Source CXCL Source RANKL RANKL Secreted Signaling 0.2206 0.0000006302774315102731 Scatter Plot
Source CXCL Source CD34 CD34 Cell-Cell Contact 0.2226 0.0000004922673245731053 Scatter Plot
Source CXCL Source VEGF VEGF Secreted Signaling 0.2235 0.0000004452476242595277 Scatter Plot
Target CXCL Target CEACAM CEACAM Cell-Cell Contact 0.2341 0.00000011868591817528196 Scatter Plot
Target CXCL Target IL17 IL17 Secreted Signaling 0.2343 0.00000011520646916181323 Scatter Plot
Target CXCL Source APP APP Cell-Cell Contact 0.2355 0.00000009941132085127633 Scatter Plot
Target CXCL Source SPP1 SPP1 Secreted Signaling 0.2381 0.000000070632504284748 Scatter Plot
Target CXCL Target SEMA3 SEMA3 Secreted Signaling 0.2383 0.00000006903078328627916 Scatter Plot
Source CXCL Source LIGHT LIGHT Secreted Signaling 0.2451 0.000000028380384349337385 Scatter Plot
Source CXCL Source CSF CSF Secreted Signaling 0.2480 0.000000019033278968464863 Scatter Plot
Target CXCL Source CCL CCL Secreted Signaling 0.2542 0.000000008201644009814818 Scatter Plot
Source CXCL Source LAMININ LAMININ ECM-Receptor 0.2605 0.0000000033577214739490413 Scatter Plot
Source CXCL Source CD45 CD45 Cell-Cell Contact 0.2608 0.0000000032008981385351892 Scatter Plot
Source CXCL Source ICAM ICAM Cell-Cell Contact 0.2611 0.0000000030954790095382894 Scatter Plot
Target CXCL Source TNF TNF Secreted Signaling 0.2712 0.0000000007011652060800801 Scatter Plot
Source CXCL Source CDH CDH Cell-Cell Contact 0.2745 0.00000000043100486536756957 Scatter Plot
Target CXCL Target CSF CSF Secreted Signaling 0.2900 0.000000000038363329953395947 Scatter Plot
Target CXCL Source PARs PARs Secreted Signaling 0.2931 0.000000000022931569455133688 Scatter Plot
Source CXCL Source SEMA7 SEMA7 Cell-Cell Contact 0.3019 0.000000000005383870030605528 Scatter Plot
Source CXCL Source TWEAK TWEAK Secreted Signaling 0.3038 0.000000000003901300402263561 Scatter Plot
Target CXCL Source SEMA4 SEMA4 Cell-Cell Contact 0.3086 0.0000000000017076230979666028 Scatter Plot
Target CXCL Source ANNEXIN ANNEXIN Secreted Signaling 0.3105 0.0000000000012330534141002037 Scatter Plot
Source CXCL Source CX3C CX3C Secreted Signaling 0.3133 0.0000000000007528167899927442 Scatter Plot
Target CXCL Target ICAM ICAM Cell-Cell Contact 0.3138 0.0000000000006941824961061635 Scatter Plot
Target CXCL Source VISTA VISTA Cell-Cell Contact 0.3156 0.0000000000004977591425578837 Scatter Plot
Source CXCL Source FGF FGF Secreted Signaling 0.3409 0.000000000000004540892593304603 Scatter Plot
Source CXCL Source CD86 CD86 Cell-Cell Contact 0.3462 0.0000000000000015983437785950773 Scatter Plot
Target CXCL Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.3499 0.0000000000000007510548826745652 Scatter Plot
Source CXCL Source JAM JAM Cell-Cell Contact 0.3511 0.0000000000000005959426362426732 Scatter Plot
Source CXCL Source EPHB EPHB Cell-Cell Contact 0.3639 0.00000000000000004158174440488245 Scatter Plot
Target CXCL Source COMPLEMENT COMPLEMENT Secreted Signaling 0.3888 0.00000000000000000017081714621926072 Scatter Plot
Source CXCL Source COLLAGEN COLLAGEN ECM-Receptor 0.4221 0.000000000000000000000049954066706319065 Scatter Plot
Target CXCL Source SELL SELL Cell-Cell Contact 0.4243 0.00000000000000000000002873090413583603 Scatter Plot
Source CXCL Source ANGPT ANGPT Secreted Signaling 0.4244 0.000000000000000000000027598365372603604 Scatter Plot
Target CXCL Source CD52 CD52 Cell-Cell Contact 0.4504 0.000000000000000000000000023824285877613542 Scatter Plot
Target CXCL Target MK MK Secreted Signaling -0.3671 0.000000000000000021263176905834466 Scatter Plot
Target CXCL Source ANGPT ANGPT Secreted Signaling -0.3557 0.0000000000000002326551188486939 Scatter Plot
Target CXCL Source EPHB EPHB Cell-Cell Contact -0.3444 0.000000000000002269762601268012 Scatter Plot
Target CXCL Source MHC-I MHC-I Cell-Cell Contact -0.3378 0.000000000000008162107733718721 Scatter Plot
Target CXCL Target KIT KIT Secreted Signaling -0.3365 0.000000000000010463463269994246 Scatter Plot
Target CXCL Target WNT WNT Secreted Signaling -0.3208 0.0000000000001972762793351991 Scatter Plot
Source CXCL Source COMPLEMENT COMPLEMENT Secreted Signaling -0.3108 0.0000000000011683736212655125 Scatter Plot
Target CXCL Target ESAM ESAM Cell-Cell Contact -0.3010 0.0000000000062549083213247855 Scatter Plot
Target CXCL Source ESAM ESAM Cell-Cell Contact -0.3010 0.0000000000062549083213247855 Scatter Plot
Target CXCL Source JAM JAM Cell-Cell Contact -0.3008 0.0000000000064424729405059386 Scatter Plot
Source CXCL Source PARs PARs Secreted Signaling -0.3002 0.0000000000070799997698111174 Scatter Plot
Target CXCL Target TENASCIN TENASCIN ECM-Receptor -0.2943 0.000000000018949344883278217 Scatter Plot
Target CXCL Source FLT3 FLT3 Secreted Signaling -0.2912 0.00000000003127823756570361 Scatter Plot
Target CXCL Target CD34 CD34 Cell-Cell Contact -0.2857 0.00000000007529404271157425 Scatter Plot
Target CXCL Source LIFR LIFR Secreted Signaling -0.2802 0.00000000018005473306451138 Scatter Plot
Target CXCL Source COLLAGEN COLLAGEN ECM-Receptor -0.2742 0.0000000004456545018733039 Scatter Plot
Source CXCL Source SELL SELL Cell-Cell Contact -0.2731 0.0000000005290032550825046 Scatter Plot
Source CXCL Source CD52 CD52 Cell-Cell Contact -0.2697 0.0000000008760150800584679 Scatter Plot
Target CXCL Source GAS GAS Secreted Signaling -0.2682 0.0000000011060216728048854 Scatter Plot
Target CXCL Source MHC-II MHC-II Cell-Cell Contact -0.2680 0.0000000011267888464992503 Scatter Plot
Target CXCL Target VWF VWF ECM-Receptor -0.2664 0.0000000014215829350090307 Scatter Plot
Source CXCL Source VISTA VISTA Cell-Cell Contact -0.2657 0.0000000015923672640844755 Scatter Plot
Target CXCL Source TWEAK TWEAK Secreted Signaling -0.2642 0.000000001964313843498991 Scatter Plot
Target CXCL Target CD39 CD39 Cell-Cell Contact -0.2546 0.000000007767735033537049 Scatter Plot
Target CXCL Source PDGF PDGF Secreted Signaling -0.2489 0.000000016836343683554066 Scatter Plot
Target CXCL Source GP1BA GP1BA Cell-Cell Contact -0.2471 0.000000021495349614878035 Scatter Plot
Source CXCL Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.2444 0.00000003109440144605909 Scatter Plot
Target CXCL Source IL7 IL7 Secreted Signaling -0.2434 0.000000035442258983617596 Scatter Plot
Target CXCL Source SEMA7 SEMA7 Cell-Cell Contact -0.2419 0.000000043038765899280236 Scatter Plot
Target CXCL Source GALECTIN GALECTIN Secreted Signaling -0.2373 0.00000007901263877239648 Scatter Plot
Target CXCL Source BST2 BST2 Cell-Cell Contact -0.2368 0.00000008421406339242227 Scatter Plot
Target CXCL Source BMP BMP Secreted Signaling -0.2327 0.0000001414441766615049 Scatter Plot
Target CXCL Source CX3C CX3C Secreted Signaling -0.2320 0.0000001552788862855457 Scatter Plot
Target CXCL Target BMP BMP Secreted Signaling -0.2311 0.00000017304265676230725 Scatter Plot
Target CXCL Source CDH CDH Cell-Cell Contact -0.2309 0.0000001770519838427973 Scatter Plot
Source CXCL Source APP APP Cell-Cell Contact -0.2294 0.0000002137006253918249 Scatter Plot
Source CXCL Source SEMA4 SEMA4 Cell-Cell Contact -0.2219 0.0000005378400248081358 Scatter Plot
Target CXCL Target CDH CDH Cell-Cell Contact -0.2135 0.0000014449008750195085 Scatter Plot
Target CXCL Source NT NT Secreted Signaling -0.2098 0.0000022167656056698165 Scatter Plot
Source CXCL Source CLEC CLEC Cell-Cell Contact -0.2076 0.0000028326650046339666 Scatter Plot
Target CXCL Target CSPG4 CSPG4 Cell-Cell Contact -0.2042 0.000004156953661827736 Scatter Plot
Target CXCL Source VEGF VEGF Secreted Signaling -0.2031 0.000004696039726486178 Scatter Plot
Target CXCL Source LCK LCK Cell-Cell Contact -0.1983 0.000007945257600137597 Scatter Plot
Target CXCL Source VCAM VCAM Cell-Cell Contact -0.1968 0.00000930472505960203 Scatter Plot
Source CXCL Source TGFb TGFb Secreted Signaling -0.1931 0.000013696350147417814 Scatter Plot
Target CXCL Source CADM CADM Cell-Cell Contact -0.1890 0.00002095037798750669 Scatter Plot
Target CXCL Source RANKL RANKL Secreted Signaling -0.1889 0.00002128719149303915 Scatter Plot
Target CXCL Source IL2 IL2 Secreted Signaling -0.1835 0.000036535498920673725 Scatter Plot
Target CXCL Source NOTCH NOTCH Cell-Cell Contact -0.1805 0.0000492458806442336 Scatter Plot
Source CXCL Source NCAM NCAM Cell-Cell Contact -0.1804 0.00004945439742612339 Scatter Plot
Source CXCL Source GRN GRN Secreted Signaling -0.1803 0.00005033161115928396 Scatter Plot
Target CXCL Target CADM CADM Cell-Cell Contact -0.1750 0.00008354312291222369 Scatter Plot
Target CXCL Source CD1D2 CD1D2 Cell-Cell Contact -0.1742 0.0000902621275446501 Scatter Plot
Target CXCL Source LAMININ LAMININ ECM-Receptor -0.1733 0.00009856063728964637 Scatter Plot
Target CXCL Target ANGPTL ANGPTL Secreted Signaling -0.1731 0.0000997822187886182 Scatter Plot
Target CXCL Source SEMA3 SEMA3 Secreted Signaling -0.1718 0.0001125646203519 Scatter Plot
Target CXCL Target NOTCH NOTCH Cell-Cell Contact -0.1717 0.0001142955047946 Scatter Plot
Target CXCL Source CD46 CD46 Cell-Cell Contact -0.1714 0.000117827339892 Scatter Plot
Target CXCL Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1684 0.0001553148778036 Scatter Plot
Target CXCL Source CCL CCL Secreted Signaling -0.1618 0.0002799844297101 Scatter Plot
Source CXCL Source SELPLG SELPLG Cell-Cell Contact -0.1607 0.0003096250286092 Scatter Plot
Target CXCL Source ICAM ICAM Cell-Cell Contact -0.1603 0.0003202095074514 Scatter Plot
Target CXCL Source THY1 THY1 Cell-Cell Contact -0.1556 0.0004784894861204 Scatter Plot
Target CXCL Target BSP BSP ECM-Receptor -0.1543 0.0005370069625946 Scatter Plot
Target CXCL Target CD200 CD200 Cell-Cell Contact -0.1540 0.0005473780060311 Scatter Plot
Target CXCL Source MK MK Secreted Signaling -0.1500 0.0007682693048921 Scatter Plot
Source CXCL Source CCL CCL Secreted Signaling -0.1499 0.0007723115938051 Scatter Plot
Target CXCL Source ANGPTL ANGPTL Secreted Signaling -0.1497 0.0007823369483674 Scatter Plot
Target CXCL Source LIGHT LIGHT Secreted Signaling -0.1490 0.0008299579461432 Scatter Plot
Source CXCL Source MIF MIF Secreted Signaling -0.1479 0.0009088169382629 Scatter Plot
Target CXCL Source CSF CSF Secreted Signaling -0.1471 0.0009707020947176 Scatter Plot
Target CXCL Source GDF GDF Secreted Signaling -0.1462 0.0010431434410961 Scatter Plot
Target CXCL Source PROS PROS Secreted Signaling -0.1440 0.0012408304018293 Scatter Plot
Source CXCL Source ANGPTL ANGPTL Secreted Signaling -0.1421 0.0014452982258784 Scatter Plot
Target CXCL Target GDF GDF Secreted Signaling -0.1415 0.0015073832347833 Scatter Plot
Source CXCL Source SPP1 SPP1 Secreted Signaling -0.1384 0.0019168772904111 Scatter Plot
Target CXCL Source LAIR1 LAIR1 Cell-Cell Contact -0.1363 0.0022478743259899 Scatter Plot
Target CXCL Source CD39 CD39 Cell-Cell Contact -0.1338 0.0027208978254547 Scatter Plot
Target CXCL Source CD86 CD86 Cell-Cell Contact -0.1322 0.0030500890434881 Scatter Plot
Source CXCL Source NKG2D NKG2D Cell-Cell Contact -0.1296 0.0036882280626678 Scatter Plot
Target CXCL Source ncWNT ncWNT Secreted Signaling -0.1287 0.0039320270024932 Scatter Plot
Source CXCL Source TNF TNF Secreted Signaling -0.1243 0.0053860272323811 Scatter Plot
Target CXCL Source IGF IGF Secreted Signaling -0.1242 0.0054295677316335 Scatter Plot
Source CXCL Source VISFATIN VISFATIN Secreted Signaling -0.1201 0.0071836840231474 Scatter Plot
Source CXCL Source IL1 IL1 Secreted Signaling -0.1199 0.0072643153365907 Scatter Plot
Target CXCL Source CD45 CD45 Cell-Cell Contact -0.1196 0.0074291842536948 Scatter Plot
Target CXCL Target COLLAGEN COLLAGEN ECM-Receptor -0.1172 0.0087047650375484 Scatter Plot
Target CXCL Source THBS THBS ECM-Receptor -0.1136 0.0110066853934316 Scatter Plot
Source CXCL Source FGF FGF Secreted Signaling -0.1114 0.0126853186554553 Scatter Plot
Target CXCL Source AGRN AGRN ECM-Receptor -0.1104 0.0134935401788601 Scatter Plot
Target CXCL Source PTN PTN Secreted Signaling -0.1073 0.0163360712833129 Scatter Plot
Target CXCL Target EPHA EPHA Cell-Cell Contact -0.1052 0.0185862441585676 Scatter Plot
Target CXCL Source IL6 IL6 Secreted Signaling -0.1038 0.0202547728719457 Scatter Plot
Target CXCL Source FGF FGF Secreted Signaling -0.1003 0.0249372769111563 Scatter Plot
Target CXCL Source CD34 CD34 Cell-Cell Contact -0.0971 0.0298644431813852 Scatter Plot
Source CXCL Source FN1 FN1 ECM-Receptor -0.0971 0.0299003080296108 Scatter Plot
Target CXCL Target SELL SELL Cell-Cell Contact 0.0962 0.0314762797496559 Scatter Plot
Target CXCL Target LAIR1 LAIR1 Cell-Cell Contact 0.1032 0.0210290097708253 Scatter Plot
Target CXCL Target SEMA7 SEMA7 Cell-Cell Contact 0.1059 0.0178098398496787 Scatter Plot
Target CXCL Target FN1 FN1 ECM-Receptor 0.1069 0.016831770845396 Scatter Plot
Target CXCL Target GALECTIN GALECTIN Secreted Signaling 0.1069 0.0167476771112526 Scatter Plot
Target CXCL Target THY1 THY1 Cell-Cell Contact 0.1084 0.0152742160621128 Scatter Plot
Source CXCL Source OSM OSM Secreted Signaling 0.1087 0.0149839063192495 Scatter Plot
Target CXCL Target CD23 CD23 Cell-Cell Contact 0.1089 0.0148349575522617 Scatter Plot
Source CXCL Source CD45 CD45 Cell-Cell Contact 0.1126 0.0117218946042165 Scatter Plot
Source CXCL Target PECAM1 PECAM1 Cell-Cell Contact 0.1131 0.0113630168529294 Scatter Plot
Source CXCL Target TWEAK TWEAK Secreted Signaling 0.1140 0.0107141004811307 Scatter Plot
Target CXCL Target GRN GRN Secreted Signaling 0.1171 0.0087830731983497 Scatter Plot
Target CXCL Target ANGPT ANGPT Secreted Signaling 0.1295 0.003726241256238 Scatter Plot
Source CXCL Source CDH CDH Cell-Cell Contact 0.1298 0.0036524090576284 Scatter Plot
Target CXCL Target VTN VTN ECM-Receptor 0.1306 0.0034449430299182 Scatter Plot
Source CXCL Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1325 0.0030033704532666 Scatter Plot
Source CXCL Target VEGF VEGF Secreted Signaling 0.1402 0.001674271924739 Scatter Plot
Source CXCL Source ICOS ICOS Cell-Cell Contact 0.1417 0.0014860529380078 Scatter Plot
Source CXCL Target IL1 IL1 Secreted Signaling 0.1442 0.00122638659539 Scatter Plot
Source CXCL Target GALECTIN GALECTIN Secreted Signaling 0.1443 0.0012127988237808 Scatter Plot
Target CXCL Target CD34 CD34 Cell-Cell Contact 0.1446 0.0011843730637613 Scatter Plot
Source CXCL Target OSM OSM Secreted Signaling 0.1454 0.0011118076024364 Scatter Plot
Source CXCL Target CADM CADM Cell-Cell Contact 0.1459 0.0010702938221305 Scatter Plot
Target CXCL Target OSM OSM Secreted Signaling 0.1513 0.0006854281226359 Scatter Plot
Target CXCL Target VEGF VEGF Secreted Signaling 0.1521 0.000641877290305 Scatter Plot
Source CXCL Source CSF CSF Secreted Signaling 0.1564 0.0004474341249377 Scatter Plot
Target CXCL Target IL1 IL1 Secreted Signaling 0.1580 0.0003905017117899 Scatter Plot
Source CXCL Source CCL CCL Secreted Signaling 0.1621 0.0002729558747175 Scatter Plot
Source CXCL Target COLLAGEN COLLAGEN ECM-Receptor 0.1646 0.000217902449821 Scatter Plot
Target CXCL Target COLLAGEN COLLAGEN ECM-Receptor 0.1647 0.0002156965820841 Scatter Plot
Source CXCL Target THY1 THY1 Cell-Cell Contact 0.1669 0.0001782845172619 Scatter Plot
Source CXCL Target IL6 IL6 Secreted Signaling 0.1670 0.0001762312641019 Scatter Plot
Target CXCL Target JAM JAM Cell-Cell Contact 0.1689 0.0001482607842433 Scatter Plot
Source CXCL Source CD1D2 CD1D2 Cell-Cell Contact 0.1696 0.0001383717543859 Scatter Plot
Source CXCL Target CD23 CD23 Cell-Cell Contact 0.1697 0.0001367854664712 Scatter Plot
Source CXCL Source NT NT Secreted Signaling 0.1728 0.000102761702282 Scatter Plot
Source CXCL Target CSPG4 CSPG4 Cell-Cell Contact 0.1776 0.00006523342842065921 Scatter Plot
Target CXCL Target COMPLEMENT COMPLEMENT Secreted Signaling 0.1777 0.00006477630891263551 Scatter Plot
Target CXCL Target ANNEXIN ANNEXIN Secreted Signaling 0.1778 0.00006380468741683007 Scatter Plot
Source CXCL Target COMPLEMENT COMPLEMENT Secreted Signaling 0.1814 0.00004522368623765288 Scatter Plot
Source CXCL Source IL16 IL16 Secreted Signaling 0.1844 0.00003334172487110571 Scatter Plot
Source CXCL Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.1864 0.00002730190451489421 Scatter Plot
Source CXCL Target RANKL RANKL Secreted Signaling 0.1922 0.000015083488769215655 Scatter Plot
Source CXCL Source CX3C CX3C Secreted Signaling 0.1957 0.000010476164053181422 Scatter Plot
Source CXCL Target SEMA6 SEMA6 Cell-Cell Contact 0.1962 0.000009934238952925213 Scatter Plot
Source CXCL Source GALECTIN GALECTIN Secreted Signaling 0.1991 0.000007295706319306379 Scatter Plot
Source CXCL Source THY1 THY1 Cell-Cell Contact 0.2010 0.000005935847667191829 Scatter Plot
Target CXCL Target SELPLG SELPLG Cell-Cell Contact 0.2040 0.000004263731864171359 Scatter Plot
Target CXCL Target VCAM VCAM Cell-Cell Contact 0.2174 0.0000009212004610085344 Scatter Plot
Source CXCL Target EPHA EPHA Cell-Cell Contact 0.2177 0.0000008837753208137203 Scatter Plot
Source CXCL Target SEMA3 SEMA3 Secreted Signaling 0.2193 0.0000007327679807101514 Scatter Plot
Source CXCL Target PTN PTN Secreted Signaling 0.2204 0.0000006476512108343086 Scatter Plot
Source CXCL Target GAS GAS Secreted Signaling 0.2208 0.0000006175465267788957 Scatter Plot
Source CXCL Source VCAM VCAM Cell-Cell Contact 0.2220 0.0000005303180533437928 Scatter Plot
Source CXCL Source IGF IGF Secreted Signaling 0.2232 0.00000046158665561139683 Scatter Plot
Source CXCL Target SELL SELL Cell-Cell Contact 0.2244 0.0000003977968884712447 Scatter Plot
Source CXCL Target GDF GDF Secreted Signaling 0.2284 0.0000002425587018796416 Scatter Plot
Source CXCL Target NODAL NODAL Secreted Signaling 0.2289 0.00000022801521392293337 Scatter Plot
Source CXCL Target THBS THBS ECM-Receptor 0.2297 0.00000020589973517598454 Scatter Plot
Source CXCL Target SEMA5 SEMA5 Cell-Cell Contact 0.2326 0.00000014356630658823974 Scatter Plot
Source CXCL Target ANGPTL ANGPTL Secreted Signaling 0.2326 0.00000014299301418034058 Scatter Plot
Target CXCL Target CEACAM CEACAM Cell-Cell Contact 0.2331 0.00000013510855265242918 Scatter Plot
Source CXCL Target VISFATIN VISFATIN Secreted Signaling 0.2354 0.00000010115097212774344 Scatter Plot
Source CXCL Target CD22 CD22 Cell-Cell Contact 0.2368 0.00000008422245285421135 Scatter Plot
Source CXCL Target EPHB EPHB Cell-Cell Contact 0.2386 0.00000006653463679142069 Scatter Plot
Source CXCL Target SPP1 SPP1 Secreted Signaling 0.2454 0.000000027283758886548315 Scatter Plot
Source CXCL Target NPR2 NPR2 Secreted Signaling 0.2488 0.000000017141164518318092 Scatter Plot
Source CXCL Source PSAP PSAP Secreted Signaling 0.2503 0.000000014037692550801561 Scatter Plot
Source CXCL Target CDH CDH Cell-Cell Contact 0.2510 0.000000012689479612592446 Scatter Plot
Source CXCL Target NCAM NCAM Cell-Cell Contact 0.2514 0.000000012098230998381984 Scatter Plot
Source CXCL Source IL2 IL2 Secreted Signaling 0.2612 0.000000003042345612391274 Scatter Plot
Source CXCL Source BST2 BST2 Cell-Cell Contact 0.2627 0.0000000024633224641488173 Scatter Plot
Source CXCL Source PDGF PDGF Secreted Signaling 0.2693 0.0000000009378737113242076 Scatter Plot
Source CXCL Source PROS PROS Secreted Signaling 0.2694 0.0000000009145080152105093 Scatter Plot
Source CXCL Source FLT3 FLT3 Secreted Signaling 0.2706 0.0000000007740622829909138 Scatter Plot
Source CXCL Source IL1 IL1 Secreted Signaling 0.2713 0.0000000006944501892300903 Scatter Plot
Source CXCL Target SEMA7 SEMA7 Cell-Cell Contact 0.2716 0.0000000006674327905861088 Scatter Plot
Source CXCL Source MK MK Secreted Signaling 0.2735 0.0000000004998076264468809 Scatter Plot
Source CXCL Target FGF FGF Secreted Signaling 0.2755 0.00000000036730499216090374 Scatter Plot
Target CXCL Target IFN-II IFN-II Secreted Signaling 0.2762 0.00000000033264968005408216 Scatter Plot
Source CXCL Target NRG NRG Secreted Signaling 0.2797 0.00000000019278653799636407 Scatter Plot
Source CXCL Target TGFb TGFb Secreted Signaling 0.2815 0.00000000014683056129745074 Scatter Plot
Source CXCL Target AGT AGT Secreted Signaling 0.2822 0.0000000001314682189772941 Scatter Plot
Source CXCL Source COLLAGEN COLLAGEN ECM-Receptor 0.2826 0.00000000012260977500827334 Scatter Plot
Source CXCL Target IGF IGF Secreted Signaling 0.2840 0.00000000009892655438013482 Scatter Plot
Source CXCL Target BMP BMP Secreted Signaling 0.2883 0.000000000050322019740253265 Scatter Plot
Source CXCL Target JAM JAM Cell-Cell Contact 0.2928 0.000000000024251051688627824 Scatter Plot
Target CXCL Target CLEC CLEC Cell-Cell Contact 0.2983 0.000000000009727072618758332 Scatter Plot
Source CXCL Source IL7 IL7 Secreted Signaling 0.2992 0.000000000008434151703186146 Scatter Plot
Source CXCL Target MK MK Secreted Signaling 0.3010 0.000000000006225873320731965 Scatter Plot
Source CXCL Source CD86 CD86 Cell-Cell Contact 0.3051 0.000000000003112899788300759 Scatter Plot
Source CXCL Target CD200 CD200 Cell-Cell Contact 0.3055 0.0000000000028872067845992706 Scatter Plot
Source CXCL Target DMP1 DMP1 ECM-Receptor 0.3070 0.0000000000022669941385293376 Scatter Plot
Source CXCL Target SLURP SLURP Secreted Signaling 0.3071 0.000000000002204209100535403 Scatter Plot
Source CXCL Target FN1 FN1 ECM-Receptor 0.3112 0.000000000001085591627395605 Scatter Plot
Source CXCL Target ncWNT ncWNT Secreted Signaling 0.3112 0.0000000000010797479677506133 Scatter Plot
Target CXCL Target CSF CSF Secreted Signaling 0.3186 0.0000000000002907829715792104 Scatter Plot
Source CXCL Source LIFR LIFR Secreted Signaling 0.3195 0.0000000000002494276198389563 Scatter Plot
Source CXCL Target CD34 CD34 Cell-Cell Contact 0.3196 0.00000000000024540731652168734 Scatter Plot
Source CXCL Target ACTIVIN ACTIVIN Secreted Signaling 0.3228 0.0000000000001367922983977783 Scatter Plot
Source CXCL Source LCK LCK Cell-Cell Contact 0.3229 0.00000000000013488575265018085 Scatter Plot
Source CXCL Target LAMININ LAMININ ECM-Receptor 0.3244 0.0000000000001014970522610294 Scatter Plot
Target CXCL Target CD52 CD52 Cell-Cell Contact 0.3291 0.00000000000004264653553223246 Scatter Plot
Source CXCL Target WNT WNT Secreted Signaling 0.3303 0.00000000000003393572285801273 Scatter Plot
Source CXCL Source BMP BMP Secreted Signaling 0.3311 0.00000000000002914298201677561 Scatter Plot
Source CXCL Target ANGPT ANGPT Secreted Signaling 0.3332 0.000000000000019627153012481132 Scatter Plot
Source CXCL Target CD39 CD39 Cell-Cell Contact 0.3350 0.000000000000013956735646605931 Scatter Plot
Source CXCL Target PERIOSTIN PERIOSTIN Secreted Signaling 0.3376 0.000000000000008569227354624038 Scatter Plot
Source CXCL Target SEMA4 SEMA4 Cell-Cell Contact 0.3423 0.0000000000000033945747906371608 Scatter Plot
Source CXCL Target BSP BSP ECM-Receptor 0.3443 0.000000000000002321379710828377 Scatter Plot
Source CXCL Target BAFF BAFF Secreted Signaling 0.3507 0.0000000000000006393765756469285 Scatter Plot
Source CXCL Target APP APP Cell-Cell Contact 0.3521 0.0000000000000004866480773384423 Scatter Plot
Source CXCL Target VTN VTN ECM-Receptor 0.3526 0.0000000000000004349867689742476 Scatter Plot
Source CXCL Source GAS GAS Secreted Signaling 0.3588 0.0000000000000001224154768612082 Scatter Plot
Source CXCL Target ESAM ESAM Cell-Cell Contact 0.3618 0.00000000000000006558779781930666 Scatter Plot
Source CXCL Source ESAM ESAM Cell-Cell Contact 0.3618 0.00000000000000006558779781930571 Scatter Plot
Source CXCL Target KIT KIT Secreted Signaling 0.3646 0.000000000000000036275660283849095 Scatter Plot
Source CXCL Target PARs PARs Secreted Signaling 0.3699 0.000000000000000011708098254104289 Scatter Plot
Source CXCL Target VWF VWF ECM-Receptor 0.3861 0.0000000000000000003176957216451451 Scatter Plot
Source CXCL Target MIF MIF Secreted Signaling 0.3887 0.00000000000000000017438416678507262 Scatter Plot
Source CXCL Target TENASCIN TENASCIN ECM-Receptor 0.4098 0.000000000000000000001125277464316123 Scatter Plot
Source CXCL Source MHC-I MHC-I Cell-Cell Contact 0.4239 0.00000000000000000000003177755673542964 Scatter Plot
Source CXCL Source MHC-II MHC-II Cell-Cell Contact 0.4517 0.00000000000000000000000001639258851021519 Scatter Plot
Source CXCL Source COMPLEMENT COMPLEMENT Secreted Signaling -0.4069 0.000000000000000000002312891816016443 Scatter Plot
Target CXCL Target PARs PARs Secreted Signaling -0.3909 0.00000000000000000010508090682668024 Scatter Plot
Target CXCL Target ncWNT ncWNT Secreted Signaling -0.3215 0.00000000000017211904278596599 Scatter Plot
Target CXCL Target IGF IGF Secreted Signaling -0.3126 0.0000000000008451232557849176 Scatter Plot
Target CXCL Target PTN PTN Secreted Signaling -0.2936 0.00000000002111910250306668 Scatter Plot
Target CXCL Target CD34 CD34 Cell-Cell Contact -0.2841 0.00000000009706147936903927 Scatter Plot
Target CXCL Target ANGPT ANGPT Secreted Signaling -0.2805 0.00000000017174717252288234 Scatter Plot
Target CXCL Target SEMA7 SEMA7 Cell-Cell Contact -0.2712 0.000000000700588430547507 Scatter Plot
Target CXCL Target CD39 CD39 Cell-Cell Contact -0.2704 0.0000000007944666105897772 Scatter Plot
Target CXCL Target SEMA5 SEMA5 Cell-Cell Contact -0.2643 0.000000001947615046863415 Scatter Plot
Source CXCL Source CD52 CD52 Cell-Cell Contact -0.2526 0.000000010206727608185193 Scatter Plot
Target CXCL Target FGF FGF Secreted Signaling -0.2508 0.000000013141953989217042 Scatter Plot
Target CXCL Target NPR2 NPR2 Secreted Signaling -0.2429 0.00000003782253990735929 Scatter Plot
Source CXCL Target IFN-II IFN-II Secreted Signaling -0.2413 0.000000046642497306527835 Scatter Plot
Source CXCL Target ICAM ICAM Cell-Cell Contact -0.2399 0.000000056284497493970734 Scatter Plot
Target CXCL Target AGT AGT Secreted Signaling -0.2383 0.0000000687984580529543 Scatter Plot
Target CXCL Target JAM JAM Cell-Cell Contact -0.2367 0.00000008466192594675841 Scatter Plot
Target CXCL Target CDH CDH Cell-Cell Contact -0.2360 0.00000009353218739383008 Scatter Plot
Target CXCL Target SLURP SLURP Secreted Signaling -0.2335 0.00000012739231552922408 Scatter Plot
Source CXCL Target CSF CSF Secreted Signaling -0.2326 0.00000014285734412965414 Scatter Plot
Target CXCL Target THBS THBS ECM-Receptor -0.2261 0.0000003230124192409222 Scatter Plot
Source CXCL Target CD52 CD52 Cell-Cell Contact -0.2249 0.0000003739150434192615 Scatter Plot
Target CXCL Target APP APP Cell-Cell Contact -0.2221 0.000000523503579107525 Scatter Plot
Target CXCL Target SPP1 SPP1 Secreted Signaling -0.2220 0.0000005334048561888414 Scatter Plot
Source CXCL Target CCL CCL Secreted Signaling -0.2169 0.0000009737686945321557 Scatter Plot
Source CXCL Source CLEC CLEC Cell-Cell Contact -0.2152 0.000001187486859362512 Scatter Plot
Source CXCL Target VCAM VCAM Cell-Cell Contact -0.2148 0.0000012541843059772104 Scatter Plot
Target CXCL Target FN1 FN1 ECM-Receptor -0.2086 0.0000025289195494257617 Scatter Plot
Target CXCL Target CSPG4 CSPG4 Cell-Cell Contact -0.2033 0.00000458939882230117 Scatter Plot
Target CXCL Target ADIPONECTIN ADIPONECTIN Secreted Signaling -0.2028 0.000004866272929266748 Scatter Plot
Target CXCL Target LAMININ LAMININ ECM-Receptor -0.2017 0.000005458413651411195 Scatter Plot
Source CXCL Target CLEC CLEC Cell-Cell Contact -0.2011 0.000005873296703751836 Scatter Plot
Target CXCL Target SEMA4 SEMA4 Cell-Cell Contact -0.2006 0.000006198374978890024 Scatter Plot
Target CXCL Target SEMA6 SEMA6 Cell-Cell Contact -0.1941 0.000012402133240551134 Scatter Plot
Target CXCL Target VISFATIN VISFATIN Secreted Signaling -0.1933 0.000013508241137572394 Scatter Plot
Target CXCL Target VTN VTN ECM-Receptor -0.1927 0.000014361955593003053 Scatter Plot
Source CXCL Target SELPLG SELPLG Cell-Cell Contact -0.1923 0.00001498750334162699 Scatter Plot
Source CXCL Source CCL CCL Secreted Signaling -0.1922 0.000015116253756044976 Scatter Plot
Source CXCL Source ANNEXIN ANNEXIN Secreted Signaling -0.1917 0.00001594290424787962 Scatter Plot
Target CXCL Target CADM CADM Cell-Cell Contact -0.1915 0.000016249542237628716 Scatter Plot
Target CXCL Target EPHB EPHB Cell-Cell Contact -0.1858 0.00002904604164782696 Scatter Plot
Source CXCL Target IL17 IL17 Secreted Signaling -0.1791 0.00005611945121818086 Scatter Plot
Source CXCL Target SEMA3 SEMA3 Secreted Signaling -0.1716 0.0001150047542722 Scatter Plot
Source CXCL Target CEACAM CEACAM Cell-Cell Contact -0.1703 0.0001299891469124 Scatter Plot
Target CXCL Target DMP1 DMP1 ECM-Receptor -0.1651 0.0002094046152069 Scatter Plot
Target CXCL Target VEGF VEGF Secreted Signaling -0.1642 0.0002255735867183 Scatter Plot
Target CXCL Target CD200 CD200 Cell-Cell Contact -0.1600 0.0003272825869343 Scatter Plot
Target CXCL Target ACTIVIN ACTIVIN Secreted Signaling -0.1587 0.0003683095221339 Scatter Plot
Target CXCL Target BAFF BAFF Secreted Signaling -0.1546 0.0005231832905556 Scatter Plot
Target CXCL Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1543 0.0005367975477753 Scatter Plot
Target CXCL Target TGFb TGFb Secreted Signaling -0.1540 0.0005487577258946 Scatter Plot
Target CXCL Target NRG NRG Secreted Signaling -0.1525 0.000623070581624 Scatter Plot
Target CXCL Target NODAL NODAL Secreted Signaling -0.1522 0.0006359035028696 Scatter Plot
Target CXCL Target PERIOSTIN PERIOSTIN Secreted Signaling -0.1483 0.000878567801823 Scatter Plot
Target CXCL Target IFN-II IFN-II Secreted Signaling -0.1478 0.0009201823440615 Scatter Plot
Source CXCL Target VEGF VEGF Secreted Signaling -0.1347 0.0025515102013802 Scatter Plot
Target CXCL Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.1338 0.0027095461223818 Scatter Plot
Source CXCL Source BAFF BAFF Secreted Signaling -0.1327 0.002944850870848 Scatter Plot
Target CXCL Target COLLAGEN COLLAGEN ECM-Receptor -0.1232 0.0058070541003299 Scatter Plot
Target CXCL Target PDGF PDGF Secreted Signaling -0.1204 0.0070346247147122 Scatter Plot
Target CXCL Target CD22 CD22 Cell-Cell Contact -0.1196 0.0074291842536948 Scatter Plot
Target CXCL Target OSM OSM Secreted Signaling -0.1184 0.0080243063951588 Scatter Plot
Source CXCL Target GRN GRN Secreted Signaling -0.1184 0.0080632639535272 Scatter Plot
Target CXCL Target IL1 IL1 Secreted Signaling -0.1113 0.0127406754222741 Scatter Plot
Target CXCL Target RANKL RANKL Secreted Signaling -0.1068 0.0168779412327271 Scatter Plot
Source CXCL Target ANNEXIN ANNEXIN Secreted Signaling -0.1060 0.0177848217535892 Scatter Plot
Source CXCL Target COLLAGEN COLLAGEN ECM-Receptor -0.1009 0.0240610019828569 Scatter Plot

Cells that are targets of CXCL from HSCs*

Cells that are source of CXCL to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.