Pathway: PDGF

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Secreted Signaling

Details on the PDGF pathway:

Specificity Index HSPC as target: 0.614
HSPC as source: 0.329

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the PDGF pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target PDGF Source COLLAGEN COLLAGEN ECM-Receptor 0.0980 0.0285126798685106 Scatter Plot
Target PDGF Source PECAM1 PECAM1 Cell-Cell Contact 0.0991 0.0267434901091835 Scatter Plot
Target PDGF Target PECAM1 PECAM1 Cell-Cell Contact 0.0993 0.0263317098496724 Scatter Plot
Target PDGF Source MHC-I MHC-I Cell-Cell Contact 0.0998 0.0256108840225882 Scatter Plot
Target PDGF Target FN1 FN1 ECM-Receptor 0.1005 0.0245663590750286 Scatter Plot
Target PDGF Target GDF GDF Secreted Signaling 0.1030 0.0212802654348286 Scatter Plot
Target PDGF Source PTN PTN Secreted Signaling 0.1046 0.0193302839258465 Scatter Plot
Target PDGF Target SEMA3 SEMA3 Secreted Signaling 0.1085 0.015257019860863 Scatter Plot
Target PDGF Target BMP BMP Secreted Signaling 0.1089 0.0148810956045252 Scatter Plot
Target PDGF Target MK MK Secreted Signaling 0.1093 0.0144825830783719 Scatter Plot
Target PDGF Target EPHA EPHA Cell-Cell Contact 0.1096 0.0142257922798432 Scatter Plot
Target PDGF Source CCL CCL Secreted Signaling 0.1146 0.0103175242360717 Scatter Plot
Target PDGF Source ICOS ICOS Cell-Cell Contact 0.1169 0.008907599044311 Scatter Plot
Target PDGF Source LCK LCK Cell-Cell Contact 0.1182 0.0081356459858242 Scatter Plot
Target PDGF Source ICAM ICAM Cell-Cell Contact 0.1190 0.0077382156699016 Scatter Plot
Target PDGF Source MHC-II MHC-II Cell-Cell Contact 0.1202 0.0071230483506212 Scatter Plot
Target PDGF Target THBS THBS ECM-Receptor 0.1227 0.0059912010818031 Scatter Plot
Target PDGF Target SPP1 SPP1 Secreted Signaling 0.1273 0.0043619727868152 Scatter Plot
Target PDGF Target PARs PARs Secreted Signaling 0.1324 0.0030067010678287 Scatter Plot
Target PDGF Source IGF IGF Secreted Signaling 0.1349 0.0024958431941095 Scatter Plot
Source PDGF Source IL6 IL6 Secreted Signaling 0.1388 0.0018622615518809 Scatter Plot
Target PDGF Source APELIN APELIN Secreted Signaling 0.1392 0.0018137519025734 Scatter Plot
Target PDGF Source ANGPT ANGPT Secreted Signaling 0.1471 0.0009695326109443 Scatter Plot
Source PDGF Source SEMA6 SEMA6 Cell-Cell Contact 0.1504 0.0007437673346927 Scatter Plot
Target PDGF Source CD1D2 CD1D2 Cell-Cell Contact 0.1678 0.0001630503199339 Scatter Plot
Target PDGF Target NOTCH NOTCH Cell-Cell Contact 0.1764 0.00007282192072783367 Scatter Plot
Target PDGF Target TWEAK TWEAK Secreted Signaling 0.1791 0.00005651348286327565 Scatter Plot
Target PDGF Source OSM OSM Secreted Signaling 0.1830 0.000038571371338991566 Scatter Plot
Target PDGF Source SEMA4 SEMA4 Cell-Cell Contact 0.1833 0.00003717602652975217 Scatter Plot
Target PDGF Source FGF FGF Secreted Signaling 0.1854 0.00003011243686227763 Scatter Plot
Source PDGF Source WNT WNT Secreted Signaling 0.1929 0.00001400017545895698 Scatter Plot
Target PDGF Source ANGPTL ANGPTL Secreted Signaling 0.1934 0.000013318603445040438 Scatter Plot
Source PDGF Source PTN PTN Secreted Signaling 0.2164 0.0000010304881206912208 Scatter Plot
Source PDGF Source VEGF VEGF Secreted Signaling 0.2188 0.00000077697130593802 Scatter Plot
Target PDGF Source TGFb TGFb Secreted Signaling 0.2303 0.0000001927889756627852 Scatter Plot
Source PDGF Source ncWNT ncWNT Secreted Signaling 0.2374 0.00000007808266740807499 Scatter Plot
Target PDGF Source VCAM VCAM Cell-Cell Contact 0.2378 0.00000007341310421755344 Scatter Plot
Target PDGF Source THY1 THY1 Cell-Cell Contact 0.2380 0.0000000716023455110169 Scatter Plot
Source PDGF Source APELIN APELIN Secreted Signaling 0.2413 0.00000004652064227786495 Scatter Plot
Target PDGF Target KIT KIT Secreted Signaling 0.2516 0.000000011754415473044716 Scatter Plot
Target PDGF Source SELPLG SELPLG Cell-Cell Contact 0.2564 0.0000000060089476426831665 Scatter Plot
Target PDGF Source GALECTIN GALECTIN Secreted Signaling 0.2671 0.0000000012970702041387442 Scatter Plot
Source PDGF Source SEMA3 SEMA3 Secreted Signaling 0.2675 0.000000001218309938568422 Scatter Plot
Source PDGF Source CXCL CXCL Secreted Signaling 0.2693 0.0000000009378737113242076 Scatter Plot
Source PDGF Source LIGHT LIGHT Secreted Signaling 0.2740 0.00000000046471472720102287 Scatter Plot
Target PDGF Source CD34 CD34 Cell-Cell Contact 0.2978 0.000000000010678183400001624 Scatter Plot
Source PDGF Source RANKL RANKL Secreted Signaling 0.3713 0.000000000000000008631337317382294 Scatter Plot
Source PDGF Source LAMININ LAMININ ECM-Receptor 0.4135 0.0000000000000000000004446691743401794 Scatter Plot
Source PDGF Source PSAP PSAP Secreted Signaling 0.4174 0.0000000000000000000001665603942176717 Scatter Plot
Source PDGF Source PROS PROS Secreted Signaling 0.4712 0.00000000000000000000000000005213038917919385 Scatter Plot
Source PDGF Source COLLAGEN COLLAGEN ECM-Receptor 0.5039 0.0000000000000000000000000000000014494137808498389 Scatter Plot
Source PDGF Source TWEAK TWEAK Secreted Signaling 0.5148 0.00000000000000000000000000000000003390447610278766 Scatter Plot
Source PDGF Source LIFR LIFR Secreted Signaling 0.5154 0.00000000000000000000000000000000002715468687662526 Scatter Plot
Source PDGF Source ANGPT ANGPT Secreted Signaling 0.5473 0.0000000000000000000000000000000000000002012441722944662 Scatter Plot
Source PDGF Source PARs PARs Secreted Signaling -0.3209 0.00000000000019446780230295705 Scatter Plot
Target PDGF Source VISTA VISTA Cell-Cell Contact -0.2726 0.000000000573314761689912 Scatter Plot
Target PDGF Source APP APP Cell-Cell Contact -0.2513 0.000000012112518273654641 Scatter Plot
Target PDGF Target NCAM NCAM Cell-Cell Contact -0.2279 0.0000002595635459324112 Scatter Plot
Source PDGF Source ANGPTL ANGPTL Secreted Signaling -0.2224 0.0000005076516151987087 Scatter Plot
Target PDGF Source COMPLEMENT COMPLEMENT Secreted Signaling -0.2025 0.000004989927197542372 Scatter Plot
Target PDGF Source NCAM NCAM Cell-Cell Contact -0.2004 0.0000063317799511903765 Scatter Plot
Source PDGF Source SEMA4 SEMA4 Cell-Cell Contact -0.1968 0.000009311829975196622 Scatter Plot
Target PDGF Source GRN GRN Secreted Signaling -0.1963 0.000009828050096422704 Scatter Plot
Target PDGF Target JAM JAM Cell-Cell Contact -0.1931 0.00001367317941449892 Scatter Plot
Target PDGF Source SEMA4 SEMA4 Cell-Cell Contact -0.1734 0.00009685087349171564 Scatter Plot
Target PDGF Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1688 0.0001498989447165 Scatter Plot
Target PDGF Source LAIR1 LAIR1 Cell-Cell Contact -0.1651 0.0002090834416806 Scatter Plot
Source PDGF Source VISFATIN VISFATIN Secreted Signaling -0.1589 0.0003605933770483 Scatter Plot
Source PDGF Source VISTA VISTA Cell-Cell Contact -0.1547 0.0005157576206308 Scatter Plot
Source PDGF Source NCAM NCAM Cell-Cell Contact -0.1489 0.0008355501082662 Scatter Plot
Target PDGF Target ANGPTL ANGPTL Secreted Signaling -0.1339 0.0026888155112202 Scatter Plot
Target PDGF Target CXCL CXCL Secreted Signaling -0.1204 0.0070346247147122 Scatter Plot
Source PDGF Source CD34 CD34 Cell-Cell Contact -0.1101 0.0137290704444121 Scatter Plot
Target PDGF Source SPP1 SPP1 Secreted Signaling -0.1096 0.0142445739639995 Scatter Plot
Target PDGF Source JAM JAM Cell-Cell Contact -0.1087 0.0150443062086447 Scatter Plot
Target PDGF Source BAFF BAFF Secreted Signaling -0.1040 0.0199956386545131 Scatter Plot
Target PDGF Target AGT AGT Secreted Signaling -0.1004 0.0248348364153926 Scatter Plot
Target PDGF Source PROS PROS Secreted Signaling -0.0996 0.0259178609151594 Scatter Plot
Target PDGF Target TENASCIN TENASCIN ECM-Receptor -0.0989 0.0269625785463383 Scatter Plot
Target PDGF Target APP APP Cell-Cell Contact 0.0965 0.0310346430340765 Scatter Plot
Target PDGF Target NODAL NODAL Secreted Signaling 0.0968 0.0305254188941528 Scatter Plot
Target PDGF Target PECAM1 PECAM1 Cell-Cell Contact 0.0980 0.0284467569187032 Scatter Plot
Source PDGF Source FN1 FN1 ECM-Receptor 0.1011 0.0237789911059582 Scatter Plot
Target PDGF Target CD39 CD39 Cell-Cell Contact 0.1038 0.0202271099875096 Scatter Plot
Source PDGF Target NOTCH NOTCH Cell-Cell Contact 0.1040 0.0200531919772072 Scatter Plot
Target PDGF Target IL1 IL1 Secreted Signaling 0.1201 0.007191503892563 Scatter Plot
Source PDGF Source AGRN AGRN ECM-Receptor 0.1223 0.0061577066969079 Scatter Plot
Source PDGF Target TWEAK TWEAK Secreted Signaling 0.1230 0.0058847429344051 Scatter Plot
Source PDGF Target SELPLG SELPLG Cell-Cell Contact 0.1283 0.0040680160750111 Scatter Plot
Target PDGF Target PARs PARs Secreted Signaling 0.1308 0.0033987996649187 Scatter Plot
Target PDGF Target SEMA4 SEMA4 Cell-Cell Contact 0.1366 0.0021964281485588 Scatter Plot
Source PDGF Source ICOS ICOS Cell-Cell Contact 0.1379 0.0019993097059727 Scatter Plot
Source PDGF Source THBS THBS ECM-Receptor 0.1430 0.0013474503490827 Scatter Plot
Source PDGF Source GP1BA GP1BA Cell-Cell Contact 0.1508 0.000715347461472 Scatter Plot
Source PDGF Source ANGPTL ANGPTL Secreted Signaling 0.1522 0.0006407457034628 Scatter Plot
Source PDGF Target SEMA3 SEMA3 Secreted Signaling 0.1545 0.0005273702802372 Scatter Plot
Target PDGF Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1596 0.0003383815962773 Scatter Plot
Source PDGF Target GAS GAS Secreted Signaling 0.1597 0.0003377256182159 Scatter Plot
Source PDGF Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1597 0.000335667203466 Scatter Plot
Source PDGF Source VCAM VCAM Cell-Cell Contact 0.1663 0.0001871843390736 Scatter Plot
Source PDGF Source THY1 THY1 Cell-Cell Contact 0.1703 0.0001300472474176 Scatter Plot
Source PDGF Target THY1 THY1 Cell-Cell Contact 0.1704 0.0001289153578708 Scatter Plot
Source PDGF Target CXCL CXCL Secreted Signaling 0.1733 0.00009818661201894142 Scatter Plot
Source PDGF Target COLLAGEN COLLAGEN ECM-Receptor 0.1795 0.00005422276326995224 Scatter Plot
Source PDGF Target CD23 CD23 Cell-Cell Contact 0.1803 0.00005020768052987896 Scatter Plot
Target PDGF Target TGFb TGFb Secreted Signaling 0.1861 0.00002815189427406498 Scatter Plot
Source PDGF Source PTN PTN Secreted Signaling 0.1937 0.000012865293929586782 Scatter Plot
Source PDGF Source GDF GDF Secreted Signaling 0.1939 0.000012644270574382913 Scatter Plot
Source PDGF Target NODAL NODAL Secreted Signaling 0.1956 0.000010555859766741626 Scatter Plot
Source PDGF Source IL16 IL16 Secreted Signaling 0.1962 0.000009941395887328004 Scatter Plot
Source PDGF Source CD1D2 CD1D2 Cell-Cell Contact 0.2022 0.0000051785174815967735 Scatter Plot
Source PDGF Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2253 0.0000003559346421387792 Scatter Plot
Source PDGF Target GDF GDF Secreted Signaling 0.2286 0.0000002364846083324771 Scatter Plot
Source PDGF Target MK MK Secreted Signaling 0.2319 0.00000015779635404566061 Scatter Plot
Source PDGF Source CD46 CD46 Cell-Cell Contact 0.2350 0.00000010580869420768892 Scatter Plot
Source PDGF Target IL6 IL6 Secreted Signaling 0.2373 0.0000000790085623760645 Scatter Plot
Source PDGF Target PTN PTN Secreted Signaling 0.2383 0.00000006950672470819925 Scatter Plot
Source PDGF Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.2394 0.00000005984269886853957 Scatter Plot
Source PDGF Target SPP1 SPP1 Secreted Signaling 0.2409 0.000000049249231895167584 Scatter Plot
Source PDGF Source CD86 CD86 Cell-Cell Contact 0.2475 0.00000002042772525517753 Scatter Plot
Source PDGF Target RANKL RANKL Secreted Signaling 0.2495 0.00000001556247625506181 Scatter Plot
Source PDGF Target FN1 FN1 ECM-Receptor 0.2534 0.000000009113506115792704 Scatter Plot
Source PDGF Source IL2 IL2 Secreted Signaling 0.2557 0.000000006649063042297935 Scatter Plot
Source PDGF Source CCL CCL Secreted Signaling 0.2654 0.0000000016684364042511684 Scatter Plot
Source PDGF Target EPHA EPHA Cell-Cell Contact 0.2665 0.0000000014078738017234715 Scatter Plot
Source PDGF Source CADM CADM Cell-Cell Contact 0.2794 0.00000000020378048332710963 Scatter Plot
Source PDGF Target CADM CADM Cell-Cell Contact 0.2794 0.00000000020378048332710963 Scatter Plot
Source PDGF Target NCAM NCAM Cell-Cell Contact 0.2806 0.00000000016939370803580158 Scatter Plot
Source PDGF Target ACTIVIN ACTIVIN Secreted Signaling 0.2810 0.0000000001587317560910059 Scatter Plot
Target PDGF Target SELL SELL Cell-Cell Contact 0.2880 0.000000000052343818217191 Scatter Plot
Source PDGF Target OSM OSM Secreted Signaling 0.2890 0.00000000004478041159798724 Scatter Plot
Source PDGF Source CD39 CD39 Cell-Cell Contact 0.3017 0.00000000000552516917365586 Scatter Plot
Source PDGF Target KIT KIT Secreted Signaling 0.3023 0.0000000000049846634150037095 Scatter Plot
Source PDGF Target VEGF VEGF Secreted Signaling 0.3027 0.000000000004684215373489014 Scatter Plot
Source PDGF Target ANGPTL ANGPTL Secreted Signaling 0.3075 0.0000000000020522009245607447 Scatter Plot
Source PDGF Source ICAM ICAM Cell-Cell Contact 0.3077 0.0000000000019816587391091364 Scatter Plot
Source PDGF Target CSPG4 CSPG4 Cell-Cell Contact 0.3099 0.000000000001357947394073719 Scatter Plot
Source PDGF Target SEMA6 SEMA6 Cell-Cell Contact 0.3125 0.0000000000008606287184971649 Scatter Plot
Source PDGF Target SEMA5 SEMA5 Cell-Cell Contact 0.3311 0.000000000000029474706153727664 Scatter Plot
Source PDGF Target AGT AGT Secreted Signaling 0.3344 0.000000000000015591537956738124 Scatter Plot
Source PDGF Target THBS THBS ECM-Receptor 0.3397 0.000000000000005642920654205899 Scatter Plot
Source PDGF Source CD45 CD45 Cell-Cell Contact 0.3405 0.0000000000000048987474788007 Scatter Plot
Source PDGF Target CD22 CD22 Cell-Cell Contact 0.3405 0.000000000000004898747478800701 Scatter Plot
Source PDGF Target TGFb TGFb Secreted Signaling 0.3478 0.0000000000000011588512602844102 Scatter Plot
Source PDGF Target BAFF BAFF Secreted Signaling 0.3501 0.00000000000000072521872953038855 Scatter Plot
Source PDGF Target EPHB EPHB Cell-Cell Contact 0.3529 0.0000000000000004092431160808192 Scatter Plot
Source PDGF Target SEMA7 SEMA7 Cell-Cell Contact 0.3551 0.00000000000000026535845970683993 Scatter Plot
Source PDGF Target LAMININ LAMININ ECM-Receptor 0.3553 0.0000000000000002521784866945566 Scatter Plot
Source PDGF Source LCK LCK Cell-Cell Contact 0.3713 0.000000000000000008555047503330876 Scatter Plot
Source PDGF Source CSF CSF Secreted Signaling 0.3749 0.000000000000000003915778457184995 Scatter Plot
Source PDGF Source PSAP PSAP Secreted Signaling 0.3752 0.00000000000000000363103869694044 Scatter Plot
Source PDGF Source EPHB EPHB Cell-Cell Contact 0.3936 0.00000000000000000005610067342018081 Scatter Plot
Source PDGF Target VISFATIN VISFATIN Secreted Signaling 0.3941 0.000000000000000000050029377122441725 Scatter Plot
Source PDGF Target BMP BMP Secreted Signaling 0.3960 0.00000000000000000003207104753655734 Scatter Plot
Source PDGF Target SEMA4 SEMA4 Cell-Cell Contact 0.3996 0.00000000000000000001366532410029843 Scatter Plot
Source PDGF Source IGF IGF Secreted Signaling 0.4013 0.000000000000000000008984334430196964 Scatter Plot
Source PDGF Source NT NT Secreted Signaling 0.4030 0.000000000000000000006008446106574709 Scatter Plot
Source PDGF Source MK MK Secreted Signaling 0.4178 0.00000000000000000000014957562756001172 Scatter Plot
Source PDGF Target CD200 CD200 Cell-Cell Contact 0.4285 0.000000000000000000000009530869012462227 Scatter Plot
Source PDGF Target PERIOSTIN PERIOSTIN Secreted Signaling 0.4372 0.0000000000000000000000009115571803125784 Scatter Plot
Source PDGF Target VTN VTN ECM-Receptor 0.4388 0.000000000000000000000000587585471280401 Scatter Plot
Source PDGF Target NRG NRG Secreted Signaling 0.4446 0.00000000000000000000000012012253471382668 Scatter Plot
Source PDGF Source NOTCH NOTCH Cell-Cell Contact 0.4446 0.00000000000000000000000011967670595464542 Scatter Plot
Source PDGF Source CX3C CX3C Secreted Signaling 0.4492 0.000000000000000000000000033521302140254256 Scatter Plot
Source PDGF Target BSP BSP ECM-Receptor 0.4562 0.000000000000000000000000004524430894079957 Scatter Plot
Source PDGF Target PARs PARs Secreted Signaling 0.4571 0.0000000000000000000000000034589107052270276 Scatter Plot
Source PDGF Source PROS PROS Secreted Signaling 0.4612 0.0000000000000000000000000010369977536117529 Scatter Plot
Source PDGF Target VWF VWF ECM-Receptor 0.4626 0.0000000000000000000000000006858775804702862 Scatter Plot
Source PDGF Target DMP1 DMP1 ECM-Receptor 0.4636 0.0000000000000000000000000005132781789203375 Scatter Plot
Source PDGF Source IL7 IL7 Secreted Signaling 0.4666 0.00000000000000000000000000021078273548610063 Scatter Plot
Source PDGF Target CDH CDH Cell-Cell Contact 0.4676 0.00000000000000000000000000015459592994466746 Scatter Plot
Source PDGF Source CDH CDH Cell-Cell Contact 0.4676 0.00000000000000000000000000015459592994466746 Scatter Plot
Source PDGF Target NPR2 NPR2 Secreted Signaling 0.4686 0.00000000000000000000000000011580256481322275 Scatter Plot
Source PDGF Target FGF FGF Secreted Signaling 0.4770 0.00000000000000000000000000000893238398821661 Scatter Plot
Source PDGF Target ANGPT ANGPT Secreted Signaling 0.4835 0.0000000000000000000000000000011734505397877785 Scatter Plot
Source PDGF Target APP APP Cell-Cell Contact 0.4954 0.00000000000000000000000000000002527705501219303 Scatter Plot
Source PDGF Source FLT3 FLT3 Secreted Signaling 0.4980 0.00000000000000000000000000000001056156479395209 Scatter Plot
Source PDGF Target MIF MIF Secreted Signaling 0.5020 0.0000000000000000000000000000000028117566373734948 Scatter Plot
Source PDGF Source GAS GAS Secreted Signaling 0.5032 0.000000000000000000000000000000001848798854010316 Scatter Plot
Source PDGF Target CD39 CD39 Cell-Cell Contact 0.5225 0.0000000000000000000000000000000000022078435551082968 Scatter Plot
Source PDGF Target SLURP SLURP Secreted Signaling 0.5229 0.000000000000000000000000000000000001878705443944396 Scatter Plot
Source PDGF Target IGF IGF Secreted Signaling 0.5288 0.00000000000000000000000000000000000022278472440541848 Scatter Plot
Source PDGF Source BST2 BST2 Cell-Cell Contact 0.5453 0.0000000000000000000000000000000000000004369564264419423 Scatter Plot
Source PDGF Source MHC-II MHC-II Cell-Cell Contact 0.5481 0.0000000000000000000000000000000000000001488796372343386 Scatter Plot
Source PDGF Target TENASCIN TENASCIN ECM-Receptor 0.5537 0.000000000000000000000000000000000000000016207573710826774 Scatter Plot
Source PDGF Source SEMA7 SEMA7 Cell-Cell Contact 0.5572 0.0000000000000000000000000000000000000000039305549525076496 Scatter Plot
Source PDGF Target ncWNT ncWNT Secreted Signaling 0.5768 0.000000000000000000000000000000000000000000001087923337353167 Scatter Plot
Source PDGF Source MHC-I MHC-I Cell-Cell Contact 0.5919 0.0000000000000000000000000000000000000000000000013103166745119744 Scatter Plot
Source PDGF Target WNT WNT Secreted Signaling 0.5947 0.0000000000000000000000000000000000000000000000003672493317460665 Scatter Plot
Source PDGF Target ESAM ESAM Cell-Cell Contact 0.6102 0.0000000000000000000000000000000000000000000000000002435028556086011 Scatter Plot
Source PDGF Source ESAM ESAM Cell-Cell Contact 0.6102 0.0000000000000000000000000000000000000000000000000002435028556086011 Scatter Plot
Source PDGF Source BMP BMP Secreted Signaling 0.6175 0.000000000000000000000000000000000000000000000000000006712310451575372 Scatter Plot
Source PDGF Target JAM JAM Cell-Cell Contact 0.6231 0.00000000000000000000000000000000000000000000000000000038119678732878625 Scatter Plot
Source PDGF Target CD34 CD34 Cell-Cell Contact 0.6399 0.00000000000000000000000000000000000000000000000000000000005683211067255988 Scatter Plot
Source PDGF Source JAM JAM Cell-Cell Contact 0.6888 0.000000000000000000000000000000000000000000000000000000000000000000000012895720195308124 Scatter Plot
Source PDGF Source CD52 CD52 Cell-Cell Contact -0.5445 0.00000000000000000000000000000000000000058398840048711125 Scatter Plot
Source PDGF Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.4576 0.000000000000000000000000002945266889309236 Scatter Plot
Source PDGF Target ICAM ICAM Cell-Cell Contact -0.4370 0.0000000000000000000000009647858193434176 Scatter Plot
Source PDGF Source SELL SELL Cell-Cell Contact -0.3985 0.000000000000000000017599269177359355 Scatter Plot
Source PDGF Source COMPLEMENT COMPLEMENT Secreted Signaling -0.3632 0.00000000000000004872968714341859 Scatter Plot
Source PDGF Source TGFb TGFb Secreted Signaling -0.3252 0.00000000000008869132757050583 Scatter Plot
Source PDGF Source PARs PARs Secreted Signaling -0.3224 0.0000000000001468866982865751 Scatter Plot
Source PDGF Target CD52 CD52 Cell-Cell Contact -0.3128 0.0000000000008153981678027801 Scatter Plot
Source PDGF Target IFN-II IFN-II Secreted Signaling -0.2775 0.000000000270779240390767 Scatter Plot
Source PDGF Source CLEC CLEC Cell-Cell Contact -0.2538 0.000000008597793884091681 Scatter Plot
Source PDGF Target CXCL CXCL Secreted Signaling -0.2489 0.000000016836343683554066 Scatter Plot
Source PDGF Source SELPLG SELPLG Cell-Cell Contact -0.2459 0.000000025423696201239807 Scatter Plot
Target PDGF Target CD23 CD23 Cell-Cell Contact -0.2358 0.0000000952788068733459 Scatter Plot
Target PDGF Target THY1 THY1 Cell-Cell Contact -0.2323 0.00000014888096871998717 Scatter Plot
Source PDGF Source MIF MIF Secreted Signaling -0.2275 0.000000270114705269044 Scatter Plot
Source PDGF Target CEACAM CEACAM Cell-Cell Contact -0.2231 0.0000004652052082523131 Scatter Plot
Source PDGF Source ANNEXIN ANNEXIN Secreted Signaling -0.2193 0.0000007377528212976176 Scatter Plot
Source PDGF Target VCAM VCAM Cell-Cell Contact -0.2182 0.0000008367202538429615 Scatter Plot
Source PDGF Target COLLAGEN COLLAGEN ECM-Receptor -0.2156 0.0000011399747296041522 Scatter Plot
Source PDGF Target CCL CCL Secreted Signaling -0.2094 0.000002319341960100924 Scatter Plot
Source PDGF Target CLEC CLEC Cell-Cell Contact -0.2089 0.000002444733013388037 Scatter Plot
Source PDGF Source SPP1 SPP1 Secreted Signaling -0.2071 0.000003004676422301512 Scatter Plot
Source PDGF Target CSF CSF Secreted Signaling -0.2027 0.000004884842242372535 Scatter Plot
Source PDGF Source TNF TNF Secreted Signaling -0.2023 0.000005129272279982214 Scatter Plot
Source PDGF Source CCL CCL Secreted Signaling -0.1944 0.000011961808906147446 Scatter Plot
Target PDGF Target ANNEXIN ANNEXIN Secreted Signaling -0.1575 0.0004076553900339 Scatter Plot
Source PDGF Target IL17 IL17 Secreted Signaling -0.1476 0.0009353562669608 Scatter Plot
Source PDGF Source NKG2D NKG2D Cell-Cell Contact -0.1472 0.0009607415648257 Scatter Plot
Source PDGF Target ANNEXIN ANNEXIN Secreted Signaling -0.1436 0.0012791607720345 Scatter Plot
Target PDGF Target LAIR1 LAIR1 Cell-Cell Contact -0.1403 0.0016585128816172 Scatter Plot
Target PDGF Target BST2 BST2 Cell-Cell Contact -0.1403 0.0016585128816172 Scatter Plot
Target PDGF Target CCL CCL Secreted Signaling -0.1358 0.0023449220979744 Scatter Plot
Target PDGF Target CEACAM CEACAM Cell-Cell Contact -0.1329 0.0028962315671006 Scatter Plot
Source PDGF Target SELE SELE Cell-Cell Contact -0.1312 0.003288806340624 Scatter Plot
Source PDGF Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1300 0.0035839315547853 Scatter Plot
Source PDGF Target GRN GRN Secreted Signaling -0.1205 0.0069802975953271 Scatter Plot
Target PDGF Target GRN GRN Secreted Signaling -0.1188 0.0078236744961399 Scatter Plot
Source PDGF Source LAIR1 LAIR1 Cell-Cell Contact -0.1176 0.0084684162704761 Scatter Plot
Source PDGF Target SPP1 SPP1 Secreted Signaling -0.1127 0.0116766770924049 Scatter Plot
Target PDGF Target CD86 CD86 Cell-Cell Contact -0.1102 0.0136559429758999 Scatter Plot
Source PDGF Target VEGF VEGF Secreted Signaling -0.1094 0.0143630982343692 Scatter Plot
Target PDGF Target IL1 IL1 Secreted Signaling -0.1076 0.0161302011844248 Scatter Plot
Target PDGF Target CD52 CD52 Cell-Cell Contact -0.1062 0.0175404742799282 Scatter Plot
Source PDGF Target SEMA3 SEMA3 Secreted Signaling -0.1046 0.0193231351927151 Scatter Plot
Source PDGF Target IL1 IL1 Secreted Signaling -0.1044 0.0195892248383607 Scatter Plot
Target PDGF Target VCAM VCAM Cell-Cell Contact -0.0965 0.0308859880211292 Scatter Plot

Cells that are targets of PDGF from HSCs*

Cells that are source of PDGF to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.