Pathway: SEMA7

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Cell-Cell Contact

Details on the SEMA7 pathway:

Specificity Index HSPC as target: 0.120
HSPC as source: 0.513

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the SEMA7 pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target SEMA7 Source ncWNT ncWNT Secreted Signaling 0.0995 0.0261584678182077 Scatter Plot
Source SEMA7 Source PECAM1 PECAM1 Cell-Cell Contact 0.1015 0.0232249118455703 Scatter Plot
Target SEMA7 Target SEMA3 SEMA3 Secreted Signaling 0.1047 0.0191576890864934 Scatter Plot
Target SEMA7 Source IL16 IL16 Secreted Signaling 0.1050 0.0188724740530315 Scatter Plot
Target SEMA7 Target CXCL CXCL Secreted Signaling 0.1059 0.0178098398496787 Scatter Plot
Target SEMA7 Source SEMA4 SEMA4 Cell-Cell Contact 0.1206 0.0069367950419995 Scatter Plot
Source SEMA7 Source PTN PTN Secreted Signaling 0.1254 0.0049948073759276 Scatter Plot
Source SEMA7 Source SEMA6 SEMA6 Cell-Cell Contact 0.1256 0.0049051382505139 Scatter Plot
Target SEMA7 Source PTN PTN Secreted Signaling 0.1339 0.0026893154652201 Scatter Plot
Target SEMA7 Source LIGHT LIGHT Secreted Signaling 0.1361 0.0022909071803557 Scatter Plot
Target SEMA7 Source LAMININ LAMININ ECM-Receptor 0.1367 0.0021808892291704 Scatter Plot
Target SEMA7 Source THBS THBS ECM-Receptor 0.1436 0.0012794859304848 Scatter Plot
Source SEMA7 Source IL6 IL6 Secreted Signaling 0.1587 0.0003675692486418 Scatter Plot
Target SEMA7 Source IL1 IL1 Secreted Signaling 0.1594 0.0003454322421947 Scatter Plot
Source SEMA7 Source APELIN APELIN Secreted Signaling 0.1599 0.0003314264343967 Scatter Plot
Target SEMA7 Target GDF GDF Secreted Signaling 0.1647 0.0002155897848157 Scatter Plot
Target SEMA7 Source CD1D2 CD1D2 Cell-Cell Contact 0.1684 0.0001553382691979 Scatter Plot
Target SEMA7 Source THY1 THY1 Cell-Cell Contact 0.1776 0.00006513394797149009 Scatter Plot
Target SEMA7 Target COMPLEMENT COMPLEMENT Secreted Signaling 0.1785 0.00005973696055717989 Scatter Plot
Source SEMA7 Source WNT WNT Secreted Signaling 0.1867 0.00002643898561073834 Scatter Plot
Target SEMA7 Source ICAM ICAM Cell-Cell Contact 0.1874 0.00002478730308488628 Scatter Plot
Source SEMA7 Source ANGPTL ANGPTL Secreted Signaling 0.1884 0.000022433047221164475 Scatter Plot
Target SEMA7 Source NOTCH NOTCH Cell-Cell Contact 0.1918 0.000015771701236102007 Scatter Plot
Target SEMA7 Source SEMA3 SEMA3 Secreted Signaling 0.1930 0.000013941925611814028 Scatter Plot
Target SEMA7 Source CCL CCL Secreted Signaling 0.1958 0.000010318131900340126 Scatter Plot
Target SEMA7 Source GDF GDF Secreted Signaling 0.1965 0.000009586835695039954 Scatter Plot
Target SEMA7 Source IL2 IL2 Secreted Signaling 0.2006 0.000006153265419692908 Scatter Plot
Target SEMA7 Source CSF CSF Secreted Signaling 0.2022 0.000005208993078549109 Scatter Plot
Target SEMA7 Source NT NT Secreted Signaling 0.2074 0.0000029229851509694228 Scatter Plot
Target SEMA7 Source VEGF VEGF Secreted Signaling 0.2096 0.0000022758824045497115 Scatter Plot
Target SEMA7 Source CD86 CD86 Cell-Cell Contact 0.2141 0.000001361426988147861 Scatter Plot
Target SEMA7 Source CADM CADM Cell-Cell Contact 0.2153 0.0000011770938712574758 Scatter Plot
Target SEMA7 Source RANKL RANKL Secreted Signaling 0.2235 0.0000004443293845758362 Scatter Plot
Target SEMA7 Source IGF IGF Secreted Signaling 0.2245 0.0000003921483973047155 Scatter Plot
Target SEMA7 Source FGF FGF Secreted Signaling 0.2311 0.00000017335233531776738 Scatter Plot
Source SEMA7 Source ncWNT ncWNT Secreted Signaling 0.2344 0.00000011358455526457075 Scatter Plot
Target SEMA7 Source CD46 CD46 Cell-Cell Contact 0.2413 0.00000004700799383306751 Scatter Plot
Target SEMA7 Target ACTIVIN ACTIVIN Secreted Signaling 0.2431 0.000000036652153256499366 Scatter Plot
Target SEMA7 Source CD45 CD45 Cell-Cell Contact 0.2523 0.000000010638438238055076 Scatter Plot
Target SEMA7 Source BST2 BST2 Cell-Cell Contact 0.2554 0.0000000068844085836090615 Scatter Plot
Target SEMA7 Target EPHB EPHB Cell-Cell Contact 0.2555 0.0000000068476367146343805 Scatter Plot
Target SEMA7 Source LCK LCK Cell-Cell Contact 0.2576 0.000000005074691255695061 Scatter Plot
Target SEMA7 Source PSAP PSAP Secreted Signaling 0.2583 0.000000004580380475844075 Scatter Plot
Target SEMA7 Target VEGF VEGF Secreted Signaling 0.2654 0.000000001659994142699597 Scatter Plot
Target SEMA7 Source CXCL CXCL Secreted Signaling 0.2716 0.0000000006674327905861088 Scatter Plot
Target SEMA7 Target PERIOSTIN PERIOSTIN Secreted Signaling 0.2774 0.00000000027672357041808193 Scatter Plot
Target SEMA7 Source CDH CDH Cell-Cell Contact 0.2775 0.00000000027078299733561055 Scatter Plot
Target SEMA7 Source MK MK Secreted Signaling 0.2827 0.00000000012080660738348177 Scatter Plot
Source SEMA7 Source VEGF VEGF Secreted Signaling 0.2878 0.000000000054586318004653695 Scatter Plot
Target SEMA7 Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.2892 0.00000000004345915375939121 Scatter Plot
Source SEMA7 Source SEMA3 SEMA3 Secreted Signaling 0.2899 0.00000000003845808153947088 Scatter Plot
Source SEMA7 Source GDF GDF Secreted Signaling 0.2942 0.000000000019239041266523818 Scatter Plot
Source SEMA7 Source CADM CADM Cell-Cell Contact 0.2962 0.000000000013981241105147064 Scatter Plot
Target SEMA7 Target SEMA6 SEMA6 Cell-Cell Contact 0.3013 0.000000000005952173983866593 Scatter Plot
Source SEMA7 Source IL16 IL16 Secreted Signaling 0.3042 0.0000000000036324157784331497 Scatter Plot
Target SEMA7 Source GP1BA GP1BA Cell-Cell Contact 0.3059 0.0000000000026969730524647346 Scatter Plot
Target SEMA7 Target SEMA4 SEMA4 Cell-Cell Contact 0.3140 0.0000000000006668556207150454 Scatter Plot
Target SEMA7 Source PROS PROS Secreted Signaling 0.3143 0.0000000000006301979375969028 Scatter Plot
Target SEMA7 Source GAS GAS Secreted Signaling 0.3225 0.00000000000014554029849451462 Scatter Plot
Target SEMA7 Source IL7 IL7 Secreted Signaling 0.3229 0.00000000000013516500285505492 Scatter Plot
Source SEMA7 Source CD46 CD46 Cell-Cell Contact 0.3232 0.00000000000012812140666415088 Scatter Plot
Target SEMA7 Target SLURP SLURP Secreted Signaling 0.3334 0.00000000000001894033894346364 Scatter Plot
Target SEMA7 Source CX3C CX3C Secreted Signaling 0.3343 0.000000000000016182760005966532 Scatter Plot
Source SEMA7 Source CD39 CD39 Cell-Cell Contact 0.3358 0.000000000000011993881037344703 Scatter Plot
Target SEMA7 Source GALECTIN GALECTIN Secreted Signaling 0.3367 0.000000000000010095789940659768 Scatter Plot
Target SEMA7 Target SEMA5 SEMA5 Cell-Cell Contact 0.3425 0.0000000000000033177917375045288 Scatter Plot
Source SEMA7 Source NT NT Secreted Signaling 0.3498 0.0000000000000007689257653038748 Scatter Plot
Target SEMA7 Source PDGF PDGF Secreted Signaling 0.3551 0.00000000000000026535845970683993 Scatter Plot
Source SEMA7 Source LIGHT LIGHT Secreted Signaling 0.3557 0.0000000000000002312026003395996 Scatter Plot
Target SEMA7 Source COLLAGEN COLLAGEN ECM-Receptor 0.3801 0.0000000000000000012292933905129492 Scatter Plot
Target SEMA7 Source BMP BMP Secreted Signaling 0.3843 0.0000000000000000004764442561455257 Scatter Plot
Source SEMA7 Source LAMININ LAMININ ECM-Receptor 0.3979 0.000000000000000000020309211981732303 Scatter Plot
Target SEMA7 Source FLT3 FLT3 Secreted Signaling 0.4069 0.0000000000000000000022898449929827026 Scatter Plot
Source SEMA7 Source RANKL RANKL Secreted Signaling 0.4077 0.000000000000000000001881387736641624 Scatter Plot
Target SEMA7 Source MHC-II MHC-II Cell-Cell Contact 0.4145 0.0000000000000000000003518355801007928 Scatter Plot
Source SEMA7 Source CD45 CD45 Cell-Cell Contact 0.4162 0.0000000000000000000002274316447088247 Scatter Plot
Target SEMA7 Source EPHB EPHB Cell-Cell Contact 0.4192 0.00000000000000000000010678312054534626 Scatter Plot
Target SEMA7 Target KIT KIT Secreted Signaling 0.4327 0.000000000000000000000003063080958685044 Scatter Plot
Source SEMA7 Source EPHB EPHB Cell-Cell Contact 0.4410 0.0000000000000000000000003235924253639198 Scatter Plot
Source SEMA7 Source FLT3 FLT3 Secreted Signaling 0.4432 0.00000000000000000000000017548415446498611 Scatter Plot
Source SEMA7 Source PSAP PSAP Secreted Signaling 0.4471 0.0000000000000000000000000603962124663264 Scatter Plot
Source SEMA7 Source MK MK Secreted Signaling 0.4507 0.00000000000000000000000002165220712977032 Scatter Plot
Target SEMA7 Source TWEAK TWEAK Secreted Signaling 0.4530 0.000000000000000000000000011273355850732178 Scatter Plot
Target SEMA7 Source ANGPT ANGPT Secreted Signaling 0.4580 0.000000000000000000000000002635571756615869 Scatter Plot
Target SEMA7 Source ESAM ESAM Cell-Cell Contact 0.4608 0.0000000000000000000000000011771952573169216 Scatter Plot
Source SEMA7 Source PROS PROS Secreted Signaling 0.4673 0.00000000000000000000000000017209163685028514 Scatter Plot
Target SEMA7 Source LIFR LIFR Secreted Signaling 0.4705 0.00000000000000000000000000006491625966137794 Scatter Plot
Target SEMA7 Target VWF VWF ECM-Receptor 0.4779 0.000000000000000000000000000006757064111022796 Scatter Plot
Source SEMA7 Source IL7 IL7 Secreted Signaling 0.4792 0.000000000000000000000000000004416301282104626 Scatter Plot
Source SEMA7 Source LIFR LIFR Secreted Signaling 0.4811 0.00000000000000000000000000000245121038729185 Scatter Plot
Target SEMA7 Source JAM JAM Cell-Cell Contact 0.5007 0.000000000000000000000000000000004265394458257579 Scatter Plot
Target SEMA7 Source MHC-I MHC-I Cell-Cell Contact 0.5150 0.000000000000000000000000000000000032070551504638804 Scatter Plot
Source SEMA7 Source COLLAGEN COLLAGEN ECM-Receptor 0.5235 0.0000000000000000000000000000000000015289538710569003 Scatter Plot
Source SEMA7 Source TWEAK TWEAK Secreted Signaling 0.5546 0.000000000000000000000000000000000000000011115287695627947 Scatter Plot
Source SEMA7 Source CDH CDH Cell-Cell Contact 0.5557 0.000000000000000000000000000000000000000007099809655305144 Scatter Plot
Source SEMA7 Source PDGF PDGF Secreted Signaling 0.5572 0.0000000000000000000000000000000000000000039305549525076496 Scatter Plot
Source SEMA7 Source ESAM ESAM Cell-Cell Contact 0.5994 0.00000000000000000000000000000000000000000000000004067898814756376 Scatter Plot
Source SEMA7 Source BMP BMP Secreted Signaling 0.6051 0.0000000000000000000000000000000000000000000000000027729995953235495 Scatter Plot
Source SEMA7 Source ANGPT ANGPT Secreted Signaling 0.6067 0.0000000000000000000000000000000000000000000000000013170571628365074 Scatter Plot
Source SEMA7 Source GAS GAS Secreted Signaling 0.6134 0.00000000000000000000000000000000000000000000000000005059202726082906 Scatter Plot
Source SEMA7 Source MHC-II MHC-II Cell-Cell Contact 0.6463 0.0000000000000000000000000000000000000000000000000000000000017401860027320954 Scatter Plot
Source SEMA7 Source JAM JAM Cell-Cell Contact 0.6949 0.0000000000000000000000000000000000000000000000000000000000000000000000002199771197746333 Scatter Plot
Target SEMA7 Source SELL SELL Cell-Cell Contact -0.5577 0.0000000000000000000000000000000000000000031245053084045575 Scatter Plot
Target SEMA7 Source CD52 CD52 Cell-Cell Contact -0.5320 0.00000000000000000000000000000000000006828587142954031 Scatter Plot
Target SEMA7 Source PARs PARs Secreted Signaling -0.5195 0.000000000000000000000000000000000006425534848521191 Scatter Plot
Target SEMA7 Source CCL CCL Secreted Signaling -0.4922 0.00000000000000000000000000000007141604852741061 Scatter Plot
Source SEMA7 Source CD52 CD52 Cell-Cell Contact -0.4893 0.00000000000000000000000000000018426155863937126 Scatter Plot
Target SEMA7 Source COMPLEMENT COMPLEMENT Secreted Signaling -0.4604 0.0000000000000000000000000013025378066942435 Scatter Plot
Target SEMA7 Source ANNEXIN ANNEXIN Secreted Signaling -0.4340 0.000000000000000000000002190575025058495 Scatter Plot
Target SEMA7 Source VISTA VISTA Cell-Cell Contact -0.4326 0.0000000000000000000000031556417596960964 Scatter Plot
Source SEMA7 Source TGFb TGFb Secreted Signaling -0.3891 0.00000000000000000015986438976951792 Scatter Plot
Target SEMA7 Target ICAM ICAM Cell-Cell Contact -0.3608 0.00000000000000008097658787563771 Scatter Plot
Target SEMA7 Target IL17 IL17 Secreted Signaling -0.3545 0.0000000000000002966302141887117 Scatter Plot
Source SEMA7 Source PARs PARs Secreted Signaling -0.3364 0.000000000000010733648136832386 Scatter Plot
Source SEMA7 Source SELL SELL Cell-Cell Contact -0.3305 0.000000000000033145439193369735 Scatter Plot
Target SEMA7 Source MIF MIF Secreted Signaling -0.3165 0.00000000000042361536145957543 Scatter Plot
Source SEMA7 Source MIF MIF Secreted Signaling -0.3136 0.0000000000007175101131289057 Scatter Plot
Target SEMA7 Source LAIR1 LAIR1 Cell-Cell Contact -0.3122 0.0000000000009066883535128526 Scatter Plot
Target SEMA7 Source SEMA4 SEMA4 Cell-Cell Contact -0.3105 0.0000000000012217907889650132 Scatter Plot
Target SEMA7 Target CSF CSF Secreted Signaling -0.3036 0.00000000000400284052674555 Scatter Plot
Target SEMA7 Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.3011 0.000000000006174588138736335 Scatter Plot
Target SEMA7 Source NCAM NCAM Cell-Cell Contact -0.2973 0.00000000001153450195821958 Scatter Plot
Target SEMA7 Source APP APP Cell-Cell Contact -0.2712 0.0000000006998951067900102 Scatter Plot
Target SEMA7 Target CXCL CXCL Secreted Signaling -0.2712 0.000000000700588430547507 Scatter Plot
Source SEMA7 Source SEMA4 SEMA4 Cell-Cell Contact -0.2643 0.00000000194233635062336 Scatter Plot
Source SEMA7 Source ANGPTL ANGPTL Secreted Signaling -0.2612 0.0000000030321797890422 Scatter Plot
Target SEMA7 Source CLEC CLEC Cell-Cell Contact -0.2565 0.000000005928802841712485 Scatter Plot
Target SEMA7 Source GRN GRN Secreted Signaling -0.2148 0.0000012475753711351056 Scatter Plot
Target SEMA7 Target SEMA3 SEMA3 Secreted Signaling -0.1934 0.000013257027052867732 Scatter Plot
Source SEMA7 Source VISTA VISTA Cell-Cell Contact -0.1790 0.00005710946127129224 Scatter Plot
Source SEMA7 Source NCAM NCAM Cell-Cell Contact -0.1755 0.00007936489730377906 Scatter Plot
Target SEMA7 Source SPP1 SPP1 Secreted Signaling -0.1751 0.00008249051019959529 Scatter Plot
Source SEMA7 Source SPP1 SPP1 Secreted Signaling -0.1554 0.0004862860118799 Scatter Plot
Source SEMA7 Source TNF TNF Secreted Signaling -0.1549 0.0005071059606816 Scatter Plot
Target SEMA7 Source ANGPTL ANGPTL Secreted Signaling -0.1541 0.0005432456381288 Scatter Plot
Source SEMA7 Source SELPLG SELPLG Cell-Cell Contact -0.1538 0.0005580434128438 Scatter Plot
Target SEMA7 Source SELPLG SELPLG Cell-Cell Contact -0.1387 0.001876797114789 Scatter Plot
Target SEMA7 Source VISFATIN VISFATIN Secreted Signaling -0.1355 0.0024023019526202 Scatter Plot
Target SEMA7 Source CD34 CD34 Cell-Cell Contact -0.1266 0.0045814135350234 Scatter Plot
Target SEMA7 Source TNF TNF Secreted Signaling -0.1166 0.0090471976051073 Scatter Plot
Target SEMA7 Source NKG2D NKG2D Cell-Cell Contact -0.1109 0.0130814329584168 Scatter Plot
Source SEMA7 Target PECAM1 PECAM1 Cell-Cell Contact 0.1015 0.0232249118455703 Scatter Plot
Source SEMA7 Target GAS GAS Secreted Signaling 0.1043 0.0196929139158462 Scatter Plot
Source SEMA7 Target CD45 CD45 Cell-Cell Contact 0.1053 0.0185324071337732 Scatter Plot
Target SEMA7 Target GAS GAS Secreted Signaling 0.1400 0.0016965104478235 Scatter Plot
Source SEMA7 Target GALECTIN GALECTIN Secreted Signaling 0.1520 0.0006503356738161 Scatter Plot
Source SEMA7 Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1571 0.0004202112870101 Scatter Plot
Source SEMA7 Source ICOS ICOS Cell-Cell Contact 0.1619 0.000277692001665 Scatter Plot
Target SEMA7 Target NOTCH NOTCH Cell-Cell Contact 0.1789 0.00005759348111429045 Scatter Plot
Target SEMA7 Target PTN PTN Secreted Signaling 0.1933 0.0000134719701743515 Scatter Plot
Target SEMA7 Target BAFF BAFF Secreted Signaling 0.1966 0.000009497371421108736 Scatter Plot
Target SEMA7 Target CD200 CD200 Cell-Cell Contact 0.2063 0.0000033039406647014745 Scatter Plot
Source SEMA7 Target SEMA3 SEMA3 Secreted Signaling 0.2063 0.0000032884963229558194 Scatter Plot
Source SEMA7 Target NOTCH NOTCH Cell-Cell Contact 0.2064 0.0000032489525577780835 Scatter Plot
Target SEMA7 Target OSM OSM Secreted Signaling 0.2066 0.0000031730472585970804 Scatter Plot
Source SEMA7 Source VCAM VCAM Cell-Cell Contact 0.2075 0.000002865554377369476 Scatter Plot
Source SEMA7 Target RANKL RANKL Secreted Signaling 0.2085 0.000002573129474894764 Scatter Plot
Source SEMA7 Target COLLAGEN COLLAGEN ECM-Receptor 0.2090 0.0000024198076341612688 Scatter Plot
Target SEMA7 Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2107 0.0000020120229956635923 Scatter Plot
Target SEMA7 Target CADM CADM Cell-Cell Contact 0.2153 0.0000011770938712574758 Scatter Plot
Source SEMA7 Target FN1 FN1 ECM-Receptor 0.2160 0.0000010804907556364727 Scatter Plot
Source SEMA7 Target THY1 THY1 Cell-Cell Contact 0.2244 0.0000003993813596598439 Scatter Plot
Target SEMA7 Target TGFb TGFb Secreted Signaling 0.2248 0.000000378177943693638 Scatter Plot
Target SEMA7 Target AGT AGT Secreted Signaling 0.2319 0.00000015719246904122356 Scatter Plot
Source SEMA7 Source THY1 THY1 Cell-Cell Contact 0.2331 0.0000001340402344537478 Scatter Plot
Source SEMA7 Source CD1D2 CD1D2 Cell-Cell Contact 0.2385 0.00000006743864594972393 Scatter Plot
Source SEMA7 Target EPHA EPHA Cell-Cell Contact 0.2391 0.00000006259730963851494 Scatter Plot
Source SEMA7 Target CD23 CD23 Cell-Cell Contact 0.2414 0.00000004608738882733344 Scatter Plot
Source SEMA7 Target MK MK Secreted Signaling 0.2505 0.000000013697031136142817 Scatter Plot
Source SEMA7 Target GDF GDF Secreted Signaling 0.2511 0.000000012592531907936352 Scatter Plot
Target SEMA7 Target CD22 CD22 Cell-Cell Contact 0.2523 0.000000010638438238055076 Scatter Plot
Source SEMA7 Target IL6 IL6 Secreted Signaling 0.2593 0.000000003964670540898051 Scatter Plot
Source SEMA7 Target NODAL NODAL Secreted Signaling 0.2630 0.000000002349593787423192 Scatter Plot
Target SEMA7 Target SEMA6 SEMA6 Cell-Cell Contact 0.2668 0.000000001344258480466311 Scatter Plot
Source SEMA7 Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2694 0.0000000009234752051497035 Scatter Plot
Source SEMA7 Target VEGF VEGF Secreted Signaling 0.2744 0.00000000043375180794813933 Scatter Plot
Source SEMA7 Target SPP1 SPP1 Secreted Signaling 0.2750 0.00000000039546335477407955 Scatter Plot
Target SEMA7 Target CDH CDH Cell-Cell Contact 0.2775 0.00000000027078299733561055 Scatter Plot
Target SEMA7 Target NPR2 NPR2 Secreted Signaling 0.2811 0.0000000001550254436351122 Scatter Plot
Source SEMA7 Target PTN PTN Secreted Signaling 0.2838 0.00000000010251196881507387 Scatter Plot
Target SEMA7 Target BMP BMP Secreted Signaling 0.2862 0.00000000006999489264612023 Scatter Plot
Target SEMA7 Target SEMA4 SEMA4 Cell-Cell Contact 0.2898 0.0000000000390896940522958 Scatter Plot
Source SEMA7 Target CADM CADM Cell-Cell Contact 0.2962 0.000000000013981241105147064 Scatter Plot
Source SEMA7 Target AGT AGT Secreted Signaling 0.2981 0.000000000010156535035192332 Scatter Plot
Target SEMA7 Target BSP BSP ECM-Receptor 0.3004 0.000000000006877165887924046 Scatter Plot
Source SEMA7 Target CSPG4 CSPG4 Cell-Cell Contact 0.3009 0.000000000006325479840837628 Scatter Plot
Source SEMA7 Source CXCL CXCL Secreted Signaling 0.3019 0.000000000005383870030605528 Scatter Plot
Target SEMA7 Target APP APP Cell-Cell Contact 0.3024 0.000000000004955849884512966 Scatter Plot
Target SEMA7 Target NRG NRG Secreted Signaling 0.3039 0.000000000003805482833328119 Scatter Plot
Target SEMA7 Target DMP1 DMP1 ECM-Receptor 0.3111 0.0000000000011039910071828854 Scatter Plot
Target SEMA7 Target MIF MIF Secreted Signaling 0.3131 0.0000000000007756079135033441 Scatter Plot
Source SEMA7 Target NCAM NCAM Cell-Cell Contact 0.3140 0.0000000000006654610383852336 Scatter Plot
Source SEMA7 Target SEMA6 SEMA6 Cell-Cell Contact 0.3150 0.0000000000005526687002809971 Scatter Plot
Source SEMA7 Target SEMA5 SEMA5 Cell-Cell Contact 0.3250 0.00000000000009072992731867287 Scatter Plot
Source SEMA7 Target ANGPTL ANGPTL Secreted Signaling 0.3256 0.00000000000008184313683614461 Scatter Plot
Source SEMA7 Target OSM OSM Secreted Signaling 0.3264 0.0000000000000703625177674301 Scatter Plot
Source SEMA7 Source ICAM ICAM Cell-Cell Contact 0.3308 0.000000000000031327227882451456 Scatter Plot
Target SEMA7 Target SEMA5 SEMA5 Cell-Cell Contact 0.3424 0.0000000000000033724064892309625 Scatter Plot
Source SEMA7 Source CCL CCL Secreted Signaling 0.3432 0.0000000000000028482624377498005 Scatter Plot
Source SEMA7 Target VISFATIN VISFATIN Secreted Signaling 0.3452 0.000000000000001940705295156237 Scatter Plot
Source SEMA7 Target ACTIVIN ACTIVIN Secreted Signaling 0.3553 0.0000000000000002527428709607126 Scatter Plot
Source SEMA7 Source CX3C CX3C Secreted Signaling 0.3629 0.000000000000000051334761959816 Scatter Plot
Source SEMA7 Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.3635 0.00000000000000004590576869527225 Scatter Plot
Source SEMA7 Source LCK LCK Cell-Cell Contact 0.3716 0.000000000000000008101513769849873 Scatter Plot
Source SEMA7 Target LAMININ LAMININ ECM-Receptor 0.3723 0.000000000000000006931014781122046 Scatter Plot
Source SEMA7 Target THBS THBS ECM-Receptor 0.3847 0.00000000000000000043348934476360267 Scatter Plot
Source SEMA7 Target VWF VWF ECM-Receptor 0.3867 0.00000000000000000027673672010661925 Scatter Plot
Target SEMA7 Target WNT WNT Secreted Signaling 0.3870 0.00000000000000000026066877302023823 Scatter Plot
Source SEMA7 Target VTN VTN ECM-Receptor 0.3917 0.00000000000000000008659347020149441 Scatter Plot
Target SEMA7 Target ncWNT ncWNT Secreted Signaling 0.4003 0.000000000000000000011347207668053471 Scatter Plot
Target SEMA7 Target FGF FGF Secreted Signaling 0.4036 0.0000000000000000000052082998422096585 Scatter Plot
Source SEMA7 Target PARs PARs Secreted Signaling 0.4061 0.0000000000000000000028068225740256027 Scatter Plot
Source SEMA7 Target TGFb TGFb Secreted Signaling 0.4103 0.0000000000000000000009969736273268589 Scatter Plot
Source SEMA7 Source IL2 IL2 Secreted Signaling 0.4158 0.0000000000000000000002492752378527362 Scatter Plot
Source SEMA7 Target CD22 CD22 Cell-Cell Contact 0.4162 0.0000000000000000000002274316447088247 Scatter Plot
Source SEMA7 Target KIT KIT Secreted Signaling 0.4188 0.0000000000000000000001175743421389347 Scatter Plot
Source SEMA7 Source CD86 CD86 Cell-Cell Contact 0.4206 0.00000000000000000000007376312023776967 Scatter Plot
Target SEMA7 Target CD39 CD39 Cell-Cell Contact 0.4298 0.000000000000000000000006719211010021138 Scatter Plot
Source SEMA7 Target EPHB EPHB Cell-Cell Contact 0.4307 0.0000000000000000000000053424948300218355 Scatter Plot
Target SEMA7 Target CD34 CD34 Cell-Cell Contact 0.4317 0.000000000000000000000004051177028257822 Scatter Plot
Source SEMA7 Source NOTCH NOTCH Cell-Cell Contact 0.4363 0.0000000000000000000000011655164284992991 Scatter Plot
Source SEMA7 Target BAFF BAFF Secreted Signaling 0.4532 0.00000000000000000000000001077085580164893 Scatter Plot
Source SEMA7 Source CSF CSF Secreted Signaling 0.4537 0.000000000000000000000000009101638466861488 Scatter Plot
Target SEMA7 Target ESAM ESAM Cell-Cell Contact 0.4608 0.0000000000000000000000000011771952573169216 Scatter Plot
Source SEMA7 Target SEMA4 SEMA4 Cell-Cell Contact 0.4625 0.000000000000000000000000000707842333439574 Scatter Plot
Source SEMA7 Source IGF IGF Secreted Signaling 0.4725 0.000000000000000000000000000035715707956750026 Scatter Plot
Source SEMA7 Target ANGPT ANGPT Secreted Signaling 0.4740 0.000000000000000000000000000022076275466031548 Scatter Plot
Source SEMA7 Target BMP BMP Secreted Signaling 0.4752 0.000000000000000000000000000015380063954773316 Scatter Plot
Source SEMA7 Target NRG NRG Secreted Signaling 0.4795 0.000000000000000000000000000004038084384621621 Scatter Plot
Source SEMA7 Target PERIOSTIN PERIOSTIN Secreted Signaling 0.4798 0.0000000000000000000000000000037598485945830654 Scatter Plot
Target SEMA7 Target IGF IGF Secreted Signaling 0.4804 0.0000000000000000000000000000030860408620721294 Scatter Plot
Source SEMA7 Target BSP BSP ECM-Receptor 0.4965 0.000000000000000000000000000000017083586589820672 Scatter Plot
Source SEMA7 Target DMP1 DMP1 ECM-Receptor 0.4993 0.000000000000000000000000000000006740406635644123 Scatter Plot
Source SEMA7 Target TENASCIN TENASCIN ECM-Receptor 0.5070 0.0000000000000000000000000000000005008929461563828 Scatter Plot
Source SEMA7 Target CD200 CD200 Cell-Cell Contact 0.5072 0.000000000000000000000000000000000473029804139856 Scatter Plot
Source SEMA7 Target NPR2 NPR2 Secreted Signaling 0.5090 0.0000000000000000000000000000000002587784976472745 Scatter Plot
Source SEMA7 Target CD39 CD39 Cell-Cell Contact 0.5403 0.000000000000000000000000000000000000003032964029963168 Scatter Plot
Source SEMA7 Target SLURP SLURP Secreted Signaling 0.5504 0.00000000000000000000000000000000000000005932053152027468 Scatter Plot
Source SEMA7 Source BST2 BST2 Cell-Cell Contact 0.5527 0.000000000000000000000000000000000000000023368960932166786 Scatter Plot
Source SEMA7 Target CDH CDH Cell-Cell Contact 0.5557 0.00000000000000000000000000000000000000000709980965530484 Scatter Plot
Source SEMA7 Target ncWNT ncWNT Secreted Signaling 0.5641 0.0000000000000000000000000000000000000000002329072169637814 Scatter Plot
Source SEMA7 Target FGF FGF Secreted Signaling 0.5696 0.00000000000000000000000000000000000000000002333285114019448 Scatter Plot
Source SEMA7 Target IGF IGF Secreted Signaling 0.5737 0.000000000000000000000000000000000000000000004091636501263036 Scatter Plot
Source SEMA7 Target APP APP Cell-Cell Contact 0.5783 0.00000000000000000000000000000000000000000000056720075243014395 Scatter Plot
Source SEMA7 Target WNT WNT Secreted Signaling 0.5829 0.00000000000000000000000000000000000000000000007407083710124461 Scatter Plot
Source SEMA7 Target MIF MIF Secreted Signaling 0.5928 0.0000000000000000000000000000000000000000000000008610658127024044 Scatter Plot
Source SEMA7 Target ESAM ESAM Cell-Cell Contact 0.5994 0.00000000000000000000000000000000000000000000000004067898814756376 Scatter Plot
Source SEMA7 Target CD34 CD34 Cell-Cell Contact 0.6150 0.00000000000000000000000000000000000000000000000000002247984245759868 Scatter Plot
Target SEMA7 Target PARs PARs Secreted Signaling 0.6292 0.000000000000000000000000000000000000000000000000000000016766358136862013 Scatter Plot
Source SEMA7 Target JAM JAM Cell-Cell Contact 0.6449 0.0000000000000000000000000000000000000000000000000000000000037804978094421606 Scatter Plot
Source SEMA7 Source MHC-I MHC-I Cell-Cell Contact 0.6495 0.00000000000000000000000000000000000000000000000000000000000028698953528272357 Scatter Plot
Target SEMA7 Target CD52 CD52 Cell-Cell Contact -0.4595 0.000000000000000000000000001724635958018282 Scatter Plot
Source SEMA7 Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.4220 0.00000000000000000000005120653921794042 Scatter Plot
Target SEMA7 Target VCAM VCAM Cell-Cell Contact -0.4158 0.00000000000000000000025351053412818586 Scatter Plot
Source SEMA7 Target ICAM ICAM Cell-Cell Contact -0.3916 0.00000000000000000008980589768812182 Scatter Plot
Target SEMA7 Target IFN-II IFN-II Secreted Signaling -0.3509 0.0000000000000006214788828410625 Scatter Plot
Source SEMA7 Target CD52 CD52 Cell-Cell Contact -0.3359 0.000000000000011848403828420028 Scatter Plot
Source SEMA7 Source SELL SELL Cell-Cell Contact -0.3305 0.000000000000033145439193369735 Scatter Plot
Source SEMA7 Source COMPLEMENT COMPLEMENT Secreted Signaling -0.3298 0.00000000000003736577415973173 Scatter Plot
Target SEMA7 Target CLEC CLEC Cell-Cell Contact -0.3102 0.000000000001282230407012885 Scatter Plot
Source SEMA7 Source CLEC CLEC Cell-Cell Contact -0.2859 0.00000000007322921665761894 Scatter Plot
Target SEMA7 Target CEACAM CEACAM Cell-Cell Contact -0.2681 0.000000001122325795577267 Scatter Plot
Target SEMA7 Target CCL CCL Secreted Signaling -0.2605 0.000000003380162409110004 Scatter Plot
Source SEMA7 Target CSF CSF Secreted Signaling -0.2522 0.000000010714530234376645 Scatter Plot
Source SEMA7 Target VCAM VCAM Cell-Cell Contact -0.2434 0.000000035367877094396985 Scatter Plot
Source SEMA7 Target CEACAM CEACAM Cell-Cell Contact -0.2431 0.000000036838043505966375 Scatter Plot
Source SEMA7 Target CXCL CXCL Secreted Signaling -0.2419 0.000000043038765899280236 Scatter Plot
Target SEMA7 Target VEGF VEGF Secreted Signaling -0.2364 0.0000000882020852849702 Scatter Plot
Target SEMA7 Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1960 0.000010104216264518838 Scatter Plot
Source SEMA7 Target CCL CCL Secreted Signaling -0.1902 0.000018573669756547355 Scatter Plot
Source SEMA7 Target IFN-II IFN-II Secreted Signaling -0.1815 0.00004443049092993264 Scatter Plot
Target SEMA7 Target SELPLG SELPLG Cell-Cell Contact -0.1809 0.000047322854196646655 Scatter Plot
Source SEMA7 Target IL17 IL17 Secreted Signaling -0.1792 0.00005584734063663366 Scatter Plot
Source SEMA7 Target VEGF VEGF Secreted Signaling -0.1746 0.00008680997707349273 Scatter Plot
Source SEMA7 Source CCL CCL Secreted Signaling -0.1705 0.0001276225398828 Scatter Plot
Source SEMA7 Target CLEC CLEC Cell-Cell Contact -0.1631 0.0002501400165111 Scatter Plot
Source SEMA7 Source SPP1 SPP1 Secreted Signaling -0.1555 0.0004841261663296 Scatter Plot
Source SEMA7 Source SELPLG SELPLG Cell-Cell Contact -0.1538 0.0005580434128438 Scatter Plot
Source SEMA7 Source NKG2D NKG2D Cell-Cell Contact -0.1488 0.0008453285651385 Scatter Plot
Source SEMA7 Target COLLAGEN COLLAGEN ECM-Receptor -0.1474 0.0009435485249821 Scatter Plot
Source SEMA7 Source SEMA4 SEMA4 Cell-Cell Contact -0.1424 0.0014056058704714 Scatter Plot
Target SEMA7 Target IL1 IL1 Secreted Signaling -0.1403 0.0016590252011641 Scatter Plot
Source SEMA7 Source IL1 IL1 Secreted Signaling -0.1391 0.0018232000638347 Scatter Plot
Target SEMA7 Target GRN GRN Secreted Signaling -0.1331 0.0028564691108566 Scatter Plot
Source SEMA7 Target GRN GRN Secreted Signaling -0.1308 0.0033896490169396 Scatter Plot
Source SEMA7 Target ANNEXIN ANNEXIN Secreted Signaling -0.1244 0.0053288202310049 Scatter Plot
Target SEMA7 Target SELL SELL Cell-Cell Contact -0.1137 0.010929282695342 Scatter Plot
Source SEMA7 Target ENHO ENHO Secreted Signaling -0.1026 0.0217787198446492 Scatter Plot
Source SEMA7 Source ANNEXIN ANNEXIN Secreted Signaling -0.1003 0.0248482709524521 Scatter Plot

Cells that are targets of SEMA7 from HSCs*

Cells that are source of SEMA7 to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.