Pathway: CLEC

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Cell-Cell Contact

Details on the CLEC pathway:

Specificity Index HSPC as target:
HSPC as source:

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the CLEC pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target CLEC Target ANGPTL ANGPTL Secreted Signaling 0.0996 0.0259149413418333 Scatter Plot
Target CLEC Source ICOS ICOS Cell-Cell Contact 0.1019 0.0226620246130686 Scatter Plot
Target CLEC Target GRN GRN Secreted Signaling 0.1039 0.0201765517901539 Scatter Plot
Source CLEC Source TNF TNF Secreted Signaling 0.1086 0.0151415122770208 Scatter Plot
Source CLEC Source MIF MIF Secreted Signaling 0.1120 0.0122143436047227 Scatter Plot
Target CLEC Target CD23 CD23 Cell-Cell Contact 0.1262 0.0047035105884839 Scatter Plot
Source CLEC Source ANGPTL ANGPTL Secreted Signaling 0.1297 0.0036576592818579 Scatter Plot
Source CLEC Source APP APP Cell-Cell Contact 0.1366 0.0022005103325643 Scatter Plot
Target CLEC Target VEGF VEGF Secreted Signaling 0.1398 0.0017277726554984 Scatter Plot
Source CLEC Source GRN GRN Secreted Signaling 0.1437 0.001274207490294 Scatter Plot
Target CLEC Target IL1 IL1 Secreted Signaling 0.1437 0.0012717957463803 Scatter Plot
Source CLEC Source NCAM NCAM Cell-Cell Contact 0.1444 0.0012063456537861 Scatter Plot
Target CLEC Target LAIR1 LAIR1 Cell-Cell Contact 0.1451 0.0011408750971234 Scatter Plot
Target CLEC Target BST2 BST2 Cell-Cell Contact 0.1451 0.0011408750971234 Scatter Plot
Target CLEC Target IL6 IL6 Secreted Signaling 0.1466 0.0010137737811751 Scatter Plot
Target CLEC Source CD34 CD34 Cell-Cell Contact 0.1493 0.0008144424433277 Scatter Plot
Target CLEC Source BAFF BAFF Secreted Signaling 0.1653 0.0002059547897223 Scatter Plot
Target CLEC Source VISFATIN VISFATIN Secreted Signaling 0.1674 0.0001701391490177 Scatter Plot
Target CLEC Source MIF MIF Secreted Signaling 0.1692 0.0001439902489726 Scatter Plot
Target CLEC Source NCAM NCAM Cell-Cell Contact 0.1713 0.0001182367127008 Scatter Plot
Source CLEC Source SELPLG SELPLG Cell-Cell Contact 0.1802 0.00005063577706965787 Scatter Plot
Source CLEC Source TGFb TGFb Secreted Signaling 0.1804 0.00004985240496271088 Scatter Plot
Target CLEC Target SEMA3 SEMA3 Secreted Signaling 0.1837 0.00003600735137586545 Scatter Plot
Target CLEC Target COMPLEMENT COMPLEMENT Secreted Signaling 0.1960 0.000010096688557806844 Scatter Plot
Target CLEC Target SELE SELE Cell-Cell Contact 0.2010 0.000005901941262952053 Scatter Plot
Target CLEC Target VCAM VCAM Cell-Cell Contact 0.2020 0.000005323718758236706 Scatter Plot
Target CLEC Target ANNEXIN ANNEXIN Secreted Signaling 0.2062 0.000003347631725092307 Scatter Plot
Target CLEC Source LAIR1 LAIR1 Cell-Cell Contact 0.2104 0.000002083691519864927 Scatter Plot
Target CLEC Target COLLAGEN COLLAGEN ECM-Receptor 0.2156 0.0000011355015320528468 Scatter Plot
Source CLEC Source SPP1 SPP1 Secreted Signaling 0.2259 0.0000003302627812753481 Scatter Plot
Target CLEC Source CCL CCL Secreted Signaling 0.2584 0.000000004560035947356683 Scatter Plot
Target CLEC Source GRN GRN Secreted Signaling 0.2585 0.000000004487961158829931 Scatter Plot
Target CLEC Source SPP1 SPP1 Secreted Signaling 0.2618 0.0000000027757391543191566 Scatter Plot
Target CLEC Target IL17 IL17 Secreted Signaling 0.2700 0.0000000008433329061346068 Scatter Plot
Source CLEC Source VISTA VISTA Cell-Cell Contact 0.2710 0.0000000007239356880164517 Scatter Plot
Target CLEC Source TNF TNF Secreted Signaling 0.2781 0.0000000002491091425442617 Scatter Plot
Target CLEC Target CXCL CXCL Secreted Signaling 0.2983 0.000000000009727072618758332 Scatter Plot
Source CLEC Source SEMA4 SEMA4 Cell-Cell Contact 0.2987 0.000000000009141530272513544 Scatter Plot
Target CLEC Source SELPLG SELPLG Cell-Cell Contact 0.3010 0.000000000006257950223408962 Scatter Plot
Target CLEC Target CEACAM CEACAM Cell-Cell Contact 0.3071 0.0000000000021960543455926377 Scatter Plot
Source CLEC Source COMPLEMENT COMPLEMENT Secreted Signaling 0.3175 0.00000000000035772871661507506 Scatter Plot
Source CLEC Source PARs PARs Secreted Signaling 0.3572 0.0000000000000001695486706536504 Scatter Plot
Target CLEC Target CD52 CD52 Cell-Cell Contact 0.3652 0.000000000000000031736008383306134 Scatter Plot
Source CLEC Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.3711 0.000000000000000009005694894834898 Scatter Plot
Target CLEC Target CCL CCL Secreted Signaling 0.3762 0.0000000000000000029483515276136933 Scatter Plot
Source CLEC Source SELL SELL Cell-Cell Contact 0.3896 0.00000000000000000014364551315701568 Scatter Plot
Target CLEC Source APP APP Cell-Cell Contact 0.3926 0.00000000000000000007079953497176022 Scatter Plot
Source CLEC Source CD52 CD52 Cell-Cell Contact 0.3967 0.000000000000000000026878092791905312 Scatter Plot
Target CLEC Target ICAM ICAM Cell-Cell Contact 0.4008 0.000000000000000000010091139385877599 Scatter Plot
Target CLEC Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.4042 0.0000000000000000000045016470932744 Scatter Plot
Target CLEC Source ANNEXIN ANNEXIN Secreted Signaling 0.4067 0.0000000000000000000024117584476051368 Scatter Plot
Target CLEC Source SEMA4 SEMA4 Cell-Cell Contact 0.4080 0.000000000000000000001770123999724034 Scatter Plot
Target CLEC Source PARs PARs Secreted Signaling 0.4248 0.0000000000000000000000248123467356182 Scatter Plot
Target CLEC Source VISTA VISTA Cell-Cell Contact 0.4430 0.00000000000000000000000018668116596630568 Scatter Plot
Target CLEC Target CSF CSF Secreted Signaling 0.4541 0.000000000000000000000000008204606495954182 Scatter Plot
Target CLEC Source COMPLEMENT COMPLEMENT Secreted Signaling 0.4765 0.000000000000000000000000000010493800438148429 Scatter Plot
Target CLEC Source CD52 CD52 Cell-Cell Contact 0.4806 0.000000000000000000000000000002864090900169063 Scatter Plot
Target CLEC Source SELL SELL Cell-Cell Contact 0.5208 0.00000000000000000000000000000000000410865438252466 Scatter Plot
Target CLEC Target PARs PARs Secreted Signaling -0.4231 0.00000000000000000000003868870871820052 Scatter Plot
Target CLEC Target KIT KIT Secreted Signaling -0.3939 0.00000000000000000005159085466706011 Scatter Plot
Target CLEC Source MHC-I MHC-I Cell-Cell Contact -0.3814 0.0000000000000000009209056343320833 Scatter Plot
Target CLEC Target MK MK Secreted Signaling -0.3770 0.0000000000000000024609593395814467 Scatter Plot
Source CLEC Source ESAM ESAM Cell-Cell Contact -0.3649 0.00000000000000003365957061613179 Scatter Plot
Source CLEC Source JAM JAM Cell-Cell Contact -0.3640 0.00000000000000004086691192899993 Scatter Plot
Target CLEC Source GALECTIN GALECTIN Secreted Signaling -0.3461 0.0000000000000016207788005242636 Scatter Plot
Source CLEC Source ANGPT ANGPT Secreted Signaling -0.3408 0.0000000000000046018986436461304 Scatter Plot
Source CLEC Source COLLAGEN COLLAGEN ECM-Receptor -0.3219 0.0000000000001621563304924812 Scatter Plot
Target CLEC Target IGF IGF Secreted Signaling -0.3117 0.0000000000009886348243755206 Scatter Plot
Target CLEC Target SEMA7 SEMA7 Cell-Cell Contact -0.3102 0.000000000001282230407012885 Scatter Plot
Source CLEC Source GAS GAS Secreted Signaling -0.3098 0.0000000000013823885872298754 Scatter Plot
Target CLEC Target ncWNT ncWNT Secreted Signaling -0.3045 0.000000000003478860657906551 Scatter Plot
Target CLEC Target ESAM ESAM Cell-Cell Contact -0.2985 0.000000000009531364402324832 Scatter Plot
Target CLEC Source ESAM ESAM Cell-Cell Contact -0.2985 0.000000000009531364402324832 Scatter Plot
Target CLEC Source ANGPT ANGPT Secreted Signaling -0.2971 0.000000000011866921173631676 Scatter Plot
Target CLEC Target TENASCIN TENASCIN ECM-Receptor -0.2936 0.00000000002119713798927585 Scatter Plot
Target CLEC Source EPHB EPHB Cell-Cell Contact -0.2901 0.00000000003744848360426759 Scatter Plot
Target CLEC Source FLT3 FLT3 Secreted Signaling -0.2863 0.000000000068735649287463 Scatter Plot
Source CLEC Source SEMA7 SEMA7 Cell-Cell Contact -0.2859 0.00000000007322921665761894 Scatter Plot
Target CLEC Source JAM JAM Cell-Cell Contact -0.2832 0.00000000011228062230480287 Scatter Plot
Target CLEC Target FGF FGF Secreted Signaling -0.2807 0.00000000016611713125932776 Scatter Plot
Target CLEC Source GP1BA GP1BA Cell-Cell Contact -0.2761 0.000000000334552680635323 Scatter Plot
Target CLEC Target VWF VWF ECM-Receptor -0.2757 0.00000000035565338969540626 Scatter Plot
Source CLEC Source LIFR LIFR Secreted Signaling -0.2732 0.000000000518983030264966 Scatter Plot
Target CLEC Target CD39 CD39 Cell-Cell Contact -0.2697 0.000000000886208147281915 Scatter Plot
Target CLEC Source LIFR LIFR Secreted Signaling -0.2684 0.0000000010656400142205475 Scatter Plot
Target CLEC Source MHC-II MHC-II Cell-Cell Contact -0.2675 0.0000000012092265526741816 Scatter Plot
Source CLEC Source MHC-II MHC-II Cell-Cell Contact -0.2663 0.0000000014595416304341295 Scatter Plot
Target CLEC Target ANGPT ANGPT Secreted Signaling -0.2661 0.0000000014990774045155851 Scatter Plot
Source CLEC Source FLT3 FLT3 Secreted Signaling -0.2653 0.0000000016822414867724014 Scatter Plot
Target CLEC Target CD34 CD34 Cell-Cell Contact -0.2593 0.000000003987434055943535 Scatter Plot
Source CLEC Source PDGF PDGF Secreted Signaling -0.2538 0.000000008597793884091681 Scatter Plot
Source CLEC Source EPHB EPHB Cell-Cell Contact -0.2537 0.000000008804559284684799 Scatter Plot
Target CLEC Target FN1 FN1 ECM-Receptor -0.2527 0.00000001012075111125228 Scatter Plot
Target CLEC Target WNT WNT Secreted Signaling -0.2520 0.000000011015990446837024 Scatter Plot
Target CLEC Source COLLAGEN COLLAGEN ECM-Receptor -0.2520 0.0000000110750118582564 Scatter Plot
Target CLEC Target PTN PTN Secreted Signaling -0.2466 0.00000002298046074467628 Scatter Plot
Source CLEC Source CDH CDH Cell-Cell Contact -0.2464 0.00000002380731954489926 Scatter Plot
Target CLEC Source CDH CDH Cell-Cell Contact -0.2412 0.000000047576529126127145 Scatter Plot
Target CLEC Target CDH CDH Cell-Cell Contact -0.2412 0.000000047576529126127145 Scatter Plot
Target CLEC Source VCAM VCAM Cell-Cell Contact -0.2405 0.000000052042278313159846 Scatter Plot
Target CLEC Source LCK LCK Cell-Cell Contact -0.2359 0.00000009488307966145472 Scatter Plot
Target CLEC Source BMP BMP Secreted Signaling -0.2334 0.0000001295954574693216 Scatter Plot
Target CLEC Target SEMA4 SEMA4 Cell-Cell Contact -0.2315 0.00000016435549229013745 Scatter Plot
Target CLEC Source TWEAK TWEAK Secreted Signaling -0.2257 0.00000034103558193821737 Scatter Plot
Target CLEC Source VEGF VEGF Secreted Signaling -0.2252 0.00000035910484882920416 Scatter Plot
Source CLEC Source BMP BMP Secreted Signaling -0.2224 0.0000005081234376210216 Scatter Plot
Target CLEC Target SLURP SLURP Secreted Signaling -0.2222 0.0000005163473742981921 Scatter Plot
Target CLEC Target SEMA5 SEMA5 Cell-Cell Contact -0.2205 0.0000006361808196947716 Scatter Plot
Target CLEC Target JAM JAM Cell-Cell Contact -0.2195 0.0000007216270046742752 Scatter Plot
Source CLEC Source IL7 IL7 Secreted Signaling -0.2194 0.0000007274804061185773 Scatter Plot
Source CLEC Source TWEAK TWEAK Secreted Signaling -0.2193 0.0000007342018798328253 Scatter Plot
Source CLEC Source BST2 BST2 Cell-Cell Contact -0.2191 0.0000007564113784205756 Scatter Plot
Source CLEC Source CXCL CXCL Secreted Signaling -0.2152 0.000001187486859362512 Scatter Plot
Target CLEC Source PDGF PDGF Secreted Signaling -0.2089 0.000002444733013388037 Scatter Plot
Target CLEC Target THBS THBS ECM-Receptor -0.2085 0.0000025818394239905923 Scatter Plot
Source CLEC Source MK MK Secreted Signaling -0.2064 0.000003252383247526322 Scatter Plot
Source CLEC Source PROS PROS Secreted Signaling -0.2023 0.000005101661182866964 Scatter Plot
Target CLEC Target ADIPONECTIN ADIPONECTIN Secreted Signaling -0.2015 0.000005570757800831679 Scatter Plot
Target CLEC Source CXCL CXCL Secreted Signaling -0.2011 0.000005873296703751836 Scatter Plot
Target CLEC Source NOTCH NOTCH Cell-Cell Contact -0.1939 0.000012561741140086924 Scatter Plot
Target CLEC Source GAS GAS Secreted Signaling -0.1938 0.000012725109985091524 Scatter Plot
Source CLEC Source LAMININ LAMININ ECM-Receptor -0.1896 0.00001968999407002781 Scatter Plot
Target CLEC Source FGF FGF Secreted Signaling -0.1869 0.00002591197632280217 Scatter Plot
Target CLEC Target SEMA6 SEMA6 Cell-Cell Contact -0.1810 0.000047031239227130026 Scatter Plot
Target CLEC Target VTN VTN ECM-Receptor -0.1803 0.00005030604092207365 Scatter Plot
Source CLEC Source VEGF VEGF Secreted Signaling -0.1789 0.00005732355897372774 Scatter Plot
Source CLEC Source GP1BA GP1BA Cell-Cell Contact -0.1783 0.00006084715757853343 Scatter Plot
Target CLEC Source IL7 IL7 Secreted Signaling -0.1743 0.00008957060197815013 Scatter Plot
Source CLEC Source RANKL RANKL Secreted Signaling -0.1735 0.00009645167663752376 Scatter Plot
Source CLEC Source GDF GDF Secreted Signaling -0.1725 0.0001055708196939 Scatter Plot
Target CLEC Target APP APP Cell-Cell Contact -0.1716 0.0001146641497783 Scatter Plot
Target CLEC Target VEGF VEGF Secreted Signaling -0.1699 0.00013532827822 Scatter Plot
Target CLEC Source IL2 IL2 Secreted Signaling -0.1692 0.0001433742600128 Scatter Plot
Target CLEC Source CD46 CD46 Cell-Cell Contact -0.1650 0.0002107713811547 Scatter Plot
Target CLEC Source SEMA7 SEMA7 Cell-Cell Contact -0.1631 0.0002501400165111 Scatter Plot
Target CLEC Target NPR2 NPR2 Secreted Signaling -0.1625 0.0002624855419342 Scatter Plot
Target CLEC Source BST2 BST2 Cell-Cell Contact -0.1620 0.000274520625263 Scatter Plot
Target CLEC Source CCL CCL Secreted Signaling -0.1607 0.0003087922498245 Scatter Plot
Source CLEC Source NT NT Secreted Signaling -0.1580 0.0003897747192499 Scatter Plot
Source CLEC Source ICAM ICAM Cell-Cell Contact -0.1573 0.0004138888046819 Scatter Plot
Source CLEC Source CD46 CD46 Cell-Cell Contact -0.1557 0.0004746255999756 Scatter Plot
Target CLEC Source CX3C CX3C Secreted Signaling -0.1551 0.0004983575500896 Scatter Plot
Target CLEC Target ACTIVIN ACTIVIN Secreted Signaling -0.1511 0.0006976757209893 Scatter Plot
Source CLEC Source CSF CSF Secreted Signaling -0.1497 0.0007839188834951 Scatter Plot
Target CLEC Source MK MK Secreted Signaling -0.1453 0.0011204946850749 Scatter Plot
Target CLEC Source NT NT Secreted Signaling -0.1446 0.0011898456969862 Scatter Plot
Source CLEC Source PTN PTN Secreted Signaling -0.1405 0.0016325786131019 Scatter Plot
Source CLEC Source CADM CADM Cell-Cell Contact -0.1388 0.0018582070100908 Scatter Plot
Target CLEC Target LAMININ LAMININ ECM-Receptor -0.1386 0.0018867953476897 Scatter Plot
Source CLEC Source THY1 THY1 Cell-Cell Contact -0.1356 0.0023702881341572 Scatter Plot
Target CLEC Target VISFATIN VISFATIN Secreted Signaling -0.1354 0.0024089093151239 Scatter Plot
Target CLEC Source IGF IGF Secreted Signaling -0.1334 0.0028089762246821 Scatter Plot
Target CLEC Source LAMININ LAMININ ECM-Receptor -0.1318 0.0031391180861301 Scatter Plot
Source CLEC Source IGF IGF Secreted Signaling -0.1300 0.0035891305201967 Scatter Plot
Source CLEC Source CD39 CD39 Cell-Cell Contact -0.1264 0.0046357961780041 Scatter Plot
Target CLEC Source GDF GDF Secreted Signaling -0.1244 0.0053271016249574 Scatter Plot
Target CLEC Target TGFb TGFb Secreted Signaling -0.1224 0.0061451172691373 Scatter Plot
Target CLEC Source CD86 CD86 Cell-Cell Contact -0.1215 0.0065404609198458 Scatter Plot
Target CLEC Source PTN PTN Secreted Signaling -0.1207 0.0068702397222464 Scatter Plot
Target CLEC Source RANKL RANKL Secreted Signaling -0.1174 0.0086242978479228 Scatter Plot
Source CLEC Source CCL CCL Secreted Signaling -0.1170 0.008817901530978 Scatter Plot
Target CLEC Target AGT AGT Secreted Signaling -0.1140 0.0107658008079523 Scatter Plot
Target CLEC Target BMP BMP Secreted Signaling -0.1136 0.0110151809108804 Scatter Plot
Target CLEC Source ICAM ICAM Cell-Cell Contact -0.1130 0.0114193279809679 Scatter Plot
Target CLEC Target EPHB EPHB Cell-Cell Contact -0.1127 0.0116934162037959 Scatter Plot
Target CLEC Source SEMA3 SEMA3 Secreted Signaling -0.1122 0.0120235072909065 Scatter Plot
Target CLEC Target NOTCH NOTCH Cell-Cell Contact -0.1097 0.0141306346344987 Scatter Plot
Target CLEC Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1092 0.0145651819741473 Scatter Plot
Target CLEC Target CD22 CD22 Cell-Cell Contact -0.1087 0.0149819536153502 Scatter Plot
Target CLEC Source CD45 CD45 Cell-Cell Contact -0.1087 0.0149819536153502 Scatter Plot
Target CLEC Target IL1 IL1 Secreted Signaling -0.1065 0.017235035288689 Scatter Plot
Target CLEC Source IL6 IL6 Secreted Signaling -0.1045 0.0194682958048573 Scatter Plot
Source CLEC Source LIGHT LIGHT Secreted Signaling -0.1043 0.0196546183461049 Scatter Plot
Source CLEC Source IL6 IL6 Secreted Signaling -0.0997 0.0257973996003263 Scatter Plot
Source CLEC Source SEMA3 SEMA3 Secreted Signaling -0.0983 0.0279068685054332 Scatter Plot
Source CLEC Source ncWNT ncWNT Secreted Signaling -0.0971 0.0299447905491551 Scatter Plot
Target CLEC Target ANGPTL ANGPTL Secreted Signaling -0.0967 0.0305696707111714 Scatter Plot
Source CLEC Target CD86 CD86 Cell-Cell Contact 0.0962 0.0315789639158008 Scatter Plot
Target CLEC Target GALECTIN GALECTIN Secreted Signaling 0.1005 0.0246768775847802 Scatter Plot
Source CLEC Target SELE SELE Cell-Cell Contact 0.1053 0.0185529652624288 Scatter Plot
Source CLEC Target GRN GRN Secreted Signaling 0.1124 0.011904174651798 Scatter Plot
Source CLEC Target COMPLEMENT COMPLEMENT Secreted Signaling 0.1134 0.0111972822161985 Scatter Plot
Source CLEC Target CD45 CD45 Cell-Cell Contact 0.1236 0.0056329400541187 Scatter Plot
Source CLEC Target SELPLG SELPLG Cell-Cell Contact 0.1243 0.0053628812399053 Scatter Plot
Target CLEC Target CD23 CD23 Cell-Cell Contact 0.1262 0.0047035105884839 Scatter Plot
Target CLEC Target SELL SELL Cell-Cell Contact 0.1385 0.0019018708977134 Scatter Plot
Target CLEC Target CD86 CD86 Cell-Cell Contact 0.1393 0.0017986594032308 Scatter Plot
Source CLEC Target COLLAGEN COLLAGEN ECM-Receptor 0.1430 0.0013419111188774 Scatter Plot
Source CLEC Target SEMA3 SEMA3 Secreted Signaling 0.1453 0.0011186955881752 Scatter Plot
Target CLEC Target THY1 THY1 Cell-Cell Contact 0.1581 0.0003871706694129 Scatter Plot
Source CLEC Target ANNEXIN ANNEXIN Secreted Signaling 0.1736 0.0000950909832116109 Scatter Plot
Source CLEC Target IL17 IL17 Secreted Signaling 0.1893 0.00002036248682657114 Scatter Plot
Source CLEC Target CXCL CXCL Secreted Signaling 0.1913 0.000016635826649292152 Scatter Plot
Source CLEC Target CEACAM CEACAM Cell-Cell Contact 0.1969 0.000009185224686414896 Scatter Plot
Source CLEC Target CSF CSF Secreted Signaling 0.1972 0.000008896415219651057 Scatter Plot
Source CLEC Target VCAM VCAM Cell-Cell Contact 0.2071 0.000002995264045586674 Scatter Plot
Source CLEC Source ANNEXIN ANNEXIN Secreted Signaling 0.2167 0.000001000835675223283 Scatter Plot
Source CLEC Target CCL CCL Secreted Signaling 0.2236 0.0000004395765927082748 Scatter Plot
Source CLEC Target VEGF VEGF Secreted Signaling 0.2261 0.0000003242646488786217 Scatter Plot
Source CLEC Target IFN-II IFN-II Secreted Signaling 0.2398 0.00000005706173349143554 Scatter Plot
Target CLEC Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2452 0.00000002774788454440264 Scatter Plot
Source CLEC Source CCL CCL Secreted Signaling 0.2832 0.0000000001120110334997624 Scatter Plot
Target CLEC Target CEACAM CEACAM Cell-Cell Contact 0.3071 0.0000000000021960543455926377 Scatter Plot
Source CLEC Source COMPLEMENT COMPLEMENT Secreted Signaling 0.3175 0.00000000000035772871661507506 Scatter Plot
Target CLEC Target SELPLG SELPLG Cell-Cell Contact 0.3252 0.00000000000008799782985550845 Scatter Plot
Source CLEC Target CD52 CD52 Cell-Cell Contact 0.3285 0.00000000000004791483539038155 Scatter Plot
Source CLEC Target ICAM ICAM Cell-Cell Contact 0.3354 0.000000000000012940930223008716 Scatter Plot
Target CLEC Target CD52 CD52 Cell-Cell Contact 0.3652 0.000000000000000031736008383306134 Scatter Plot
Target CLEC Target CCL CCL Secreted Signaling 0.3732 0.00000000000000000569315644693727 Scatter Plot
Source CLEC Source CD52 CD52 Cell-Cell Contact 0.3967 0.000000000000000000026878092791905312 Scatter Plot
Target CLEC Target IFN-II IFN-II Secreted Signaling 0.4129 0.0000000000000000000005239125253819353 Scatter Plot
Source CLEC Target ESAM ESAM Cell-Cell Contact -0.3649 0.00000000000000003365957061613179 Scatter Plot
Source CLEC Target CD34 CD34 Cell-Cell Contact -0.3419 0.000000000000003666845601565522 Scatter Plot
Source CLEC Source COLLAGEN COLLAGEN ECM-Receptor -0.3244 0.0000000000001027671748620276 Scatter Plot
Source CLEC Source MHC-I MHC-I Cell-Cell Contact -0.3237 0.0000000000001169814723726788 Scatter Plot
Source CLEC Target FGF FGF Secreted Signaling -0.3179 0.00000000000033087982859606613 Scatter Plot
Source CLEC Target PARs PARs Secreted Signaling -0.3095 0.0000000000014557370276711396 Scatter Plot
Source CLEC Target WNT WNT Secreted Signaling -0.3037 0.00000000000395293172882242 Scatter Plot
Source CLEC Target JAM JAM Cell-Cell Contact -0.3035 0.00000000000409996140318877 Scatter Plot
Source CLEC Target ncWNT ncWNT Secreted Signaling -0.2947 0.00000000001772695048151394 Scatter Plot
Source CLEC Target VWF VWF ECM-Receptor -0.2906 0.00000000003457173649161974 Scatter Plot
Source CLEC Target ANGPT ANGPT Secreted Signaling -0.2829 0.0000000001171658190160411 Scatter Plot
Source CLEC Target CD39 CD39 Cell-Cell Contact -0.2811 0.00000000015494914795381374 Scatter Plot
Source CLEC Target TENASCIN TENASCIN ECM-Receptor -0.2776 0.0000000002666614692534517 Scatter Plot
Source CLEC Target SLURP SLURP Secreted Signaling -0.2728 0.0000000005531151895287756 Scatter Plot
Source CLEC Target DMP1 DMP1 ECM-Receptor -0.2725 0.000000000575541218800829 Scatter Plot
Source CLEC Target SPP1 SPP1 Secreted Signaling -0.2699 0.0000000008602846358793483 Scatter Plot
Source CLEC Target IGF IGF Secreted Signaling -0.2693 0.0000000009290498938909451 Scatter Plot
Target CLEC Target CD34 CD34 Cell-Cell Contact -0.2593 0.000000003987434055943562 Scatter Plot
Source CLEC Target BSP BSP ECM-Receptor -0.2574 0.000000005208990866730989 Scatter Plot
Source CLEC Target SEMA7 SEMA7 Cell-Cell Contact -0.2565 0.000000005928802841712485 Scatter Plot
Source CLEC Target CDH CDH Cell-Cell Contact -0.2464 0.00000002380731954489926 Scatter Plot
Source CLEC Target MK MK Secreted Signaling -0.2409 0.00000004915792962226648 Scatter Plot
Source CLEC Source LCK LCK Cell-Cell Contact -0.2395 0.000000059356480641219075 Scatter Plot
Source CLEC Target NRG NRG Secreted Signaling -0.2364 0.00000008864598820169156 Scatter Plot
Source CLEC Target VTN VTN ECM-Receptor -0.2350 0.00000010524481095223317 Scatter Plot
Source CLEC Target PTN PTN Secreted Signaling -0.2328 0.0000001397971565844399 Scatter Plot
Source CLEC Target PERIOSTIN PERIOSTIN Secreted Signaling -0.2320 0.0000001548728461244469 Scatter Plot
Source CLEC Target ACTIVIN ACTIVIN Secreted Signaling -0.2313 0.0000001687301257580789 Scatter Plot
Source CLEC Target KIT KIT Secreted Signaling -0.2275 0.00000027330482878510365 Scatter Plot
Source CLEC Target APP APP Cell-Cell Contact -0.2272 0.0000002825658759339821 Scatter Plot
Source CLEC Target BMP BMP Secreted Signaling -0.2207 0.0000006188949845779892 Scatter Plot
Source CLEC Target VEGF VEGF Secreted Signaling -0.2201 0.0000006694715854896263 Scatter Plot
Source CLEC Target SEMA5 SEMA5 Cell-Cell Contact -0.2200 0.0000006797249856882054 Scatter Plot
Source CLEC Target NPR2 NPR2 Secreted Signaling -0.2138 0.0000013953100018328034 Scatter Plot
Source CLEC Source CXCL CXCL Secreted Signaling -0.2076 0.0000028326650046339666 Scatter Plot
Target CLEC Target SPP1 SPP1 Secreted Signaling -0.2052 0.000003739638193807024 Scatter Plot
Source CLEC Source CX3C CX3C Secreted Signaling -0.2051 0.0000037467424366419593 Scatter Plot
Source CLEC Target AGT AGT Secreted Signaling -0.2019 0.00000534131720924043 Scatter Plot
Source CLEC Target ANGPTL ANGPTL Secreted Signaling -0.2011 0.000005861476205320156 Scatter Plot
Source CLEC Target LAMININ LAMININ ECM-Receptor -0.1985 0.000007770253797594216 Scatter Plot
Source CLEC Source CD86 CD86 Cell-Cell Contact -0.1965 0.000009587807186382376 Scatter Plot
Source CLEC Target SEMA4 SEMA4 Cell-Cell Contact -0.1932 0.000013580774562706116 Scatter Plot
Source CLEC Target MIF MIF Secreted Signaling -0.1917 0.000015945583167959785 Scatter Plot
Source CLEC Source IL2 IL2 Secreted Signaling -0.1893 0.00002026134679362892 Scatter Plot
Source CLEC Target VISFATIN VISFATIN Secreted Signaling -0.1884 0.000022426133798349887 Scatter Plot
Source CLEC Target FN1 FN1 ECM-Receptor -0.1855 0.000029972317472484215 Scatter Plot
Source CLEC Target EPHB EPHB Cell-Cell Contact -0.1832 0.00003751531351485194 Scatter Plot
Source CLEC Source NOTCH NOTCH Cell-Cell Contact -0.1830 0.00003826275778144974 Scatter Plot
Source CLEC Target ADIPONECTIN ADIPONECTIN Secreted Signaling -0.1775 0.00006571653180729509 Scatter Plot
Source CLEC Target NODAL NODAL Secreted Signaling -0.1694 0.0001408120731759 Scatter Plot
Source CLEC Target SEMA6 SEMA6 Cell-Cell Contact -0.1689 0.0001474454002121 Scatter Plot
Source CLEC Target THBS THBS ECM-Receptor -0.1649 0.0002125399578707 Scatter Plot
Target CLEC Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.1564 0.0004490877398082 Scatter Plot
Source CLEC Target TGFb TGFb Secreted Signaling -0.1562 0.0004552419560576 Scatter Plot
Source CLEC Source CSF CSF Secreted Signaling -0.1497 0.0007839188834951 Scatter Plot
Source CLEC Target GDF GDF Secreted Signaling -0.1496 0.0007896589453226 Scatter Plot
Source CLEC Target CD200 CD200 Cell-Cell Contact -0.1459 0.0010675257283451 Scatter Plot
Source CLEC Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1407 0.0016066657475015 Scatter Plot
Source CLEC Target CADM CADM Cell-Cell Contact -0.1388 0.0018582070100908 Scatter Plot
Source CLEC Source GALECTIN GALECTIN Secreted Signaling -0.1365 0.0022249331324707 Scatter Plot
Target CLEC Target BAFF BAFF Secreted Signaling -0.1283 0.0040659753418175 Scatter Plot
Source CLEC Source VCAM VCAM Cell-Cell Contact -0.1247 0.0052191839370613 Scatter Plot
Source CLEC Target OSM OSM Secreted Signaling -0.1205 0.0069898665256972 Scatter Plot
Target CLEC Target CD22 CD22 Cell-Cell Contact -0.1087 0.0149819536153502 Scatter Plot
Source CLEC Source CCL CCL Secreted Signaling -0.1050 0.0188539191093514 Scatter Plot
Source CLEC Target NOTCH NOTCH Cell-Cell Contact -0.1032 0.0210074372837383 Scatter Plot
Source CLEC Source ANGPTL ANGPTL Secreted Signaling -0.1019 0.0226892376823158 Scatter Plot
Source CLEC Target GAS GAS Secreted Signaling -0.1012 0.0236402027711732 Scatter Plot
Source CLEC Target BAFF BAFF Secreted Signaling -0.1010 0.023925909264812 Scatter Plot

Cells that are targets of CLEC from HSCs*

Cells that are source of CLEC to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.