Pathway: VCAM

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Cell-Cell Contact

Details on the VCAM pathway:

Specificity Index HSPC as target: 0.553
HSPC as source: 0.122

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the VCAM pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target VCAM Target SELE SELE Cell-Cell Contact 0.1126 0.0117763819212701 Scatter Plot
Source VCAM Source CADM CADM Cell-Cell Contact 0.1143 0.0105655723988841 Scatter Plot
Target VCAM Source NKG2D NKG2D Cell-Cell Contact 0.1182 0.0081503147666007 Scatter Plot
Target VCAM Source IL2 IL2 Secreted Signaling 0.1229 0.0059388509375043 Scatter Plot
Source VCAM Source PROS PROS Secreted Signaling 0.1301 0.0035587972517432 Scatter Plot
Source VCAM Source VEGF VEGF Secreted Signaling 0.1402 0.0016784603527722 Scatter Plot
Source VCAM Source CD39 CD39 Cell-Cell Contact 0.1410 0.00157111717593 Scatter Plot
Source VCAM Source CDH CDH Cell-Cell Contact 0.1414 0.0015218320088133 Scatter Plot
Source VCAM Source PDGF PDGF Secreted Signaling 0.1663 0.0001871843390736 Scatter Plot
Target VCAM Source TNF TNF Secreted Signaling 0.1674 0.0001696214000193 Scatter Plot
Target VCAM Target IL17 IL17 Secreted Signaling 0.1695 0.0001396179713147 Scatter Plot
Target VCAM Target COLLAGEN COLLAGEN ECM-Receptor 0.1713 0.0001188767513036 Scatter Plot
Source VCAM Source IGF IGF Secreted Signaling 0.1765 0.00007276623706276334 Scatter Plot
Source VCAM Source FLT3 FLT3 Secreted Signaling 0.1854 0.00003026561620129737 Scatter Plot
Source VCAM Source ANGPTL ANGPTL Secreted Signaling 0.1902 0.0000185779119577204 Scatter Plot
Source VCAM Source BST2 BST2 Cell-Cell Contact 0.1914 0.00001640773507299504 Scatter Plot
Source VCAM Source CX3C CX3C Secreted Signaling 0.1923 0.000014872437662713075 Scatter Plot
Source VCAM Source BMP BMP Secreted Signaling 0.1960 0.000010149257453785449 Scatter Plot
Source VCAM Source CD34 CD34 Cell-Cell Contact 0.1992 0.000007176217710171037 Scatter Plot
Target VCAM Source CCL CCL Secreted Signaling 0.1999 0.000006684375091062577 Scatter Plot
Target VCAM Target SEMA3 SEMA3 Secreted Signaling 0.2003 0.000006404996179009069 Scatter Plot
Target VCAM Source CLEC CLEC Cell-Cell Contact 0.2071 0.000002995264045586674 Scatter Plot
Source VCAM Source SEMA7 SEMA7 Cell-Cell Contact 0.2075 0.000002865554377369476 Scatter Plot
Source VCAM Source GDF GDF Secreted Signaling 0.2095 0.000002308164774338266 Scatter Plot
Source VCAM Source IL7 IL7 Secreted Signaling 0.2113 0.00000186390495895622 Scatter Plot
Target VCAM Target CXCL CXCL Secreted Signaling 0.2174 0.0000009212004610085344 Scatter Plot
Source VCAM Source CXCL CXCL Secreted Signaling 0.2220 0.0000005303180533437928 Scatter Plot
Source VCAM Source SELPLG SELPLG Cell-Cell Contact 0.2227 0.0000004888523252829681 Scatter Plot
Target VCAM Source SPP1 SPP1 Secreted Signaling 0.2270 0.0000002888435270007974 Scatter Plot
Source VCAM Source CD1D2 CD1D2 Cell-Cell Contact 0.2280 0.00000025424169237856933 Scatter Plot
Source VCAM Source CD45 CD45 Cell-Cell Contact 0.2345 0.00000011234402341554647 Scatter Plot
Source VCAM Source JAM JAM Cell-Cell Contact 0.2369 0.00000008314316570131397 Scatter Plot
Target VCAM Source GRN GRN Secreted Signaling 0.2430 0.00000003734254859108128 Scatter Plot
Source VCAM Source LIFR LIFR Secreted Signaling 0.2497 0.000000015118694627564722 Scatter Plot
Source VCAM Source OSM OSM Secreted Signaling 0.2589 0.000000004230904891554029 Scatter Plot
Target VCAM Target NCAM NCAM Cell-Cell Contact 0.2609 0.0000000031719030245404093 Scatter Plot
Source VCAM Source PSAP PSAP Secreted Signaling 0.2647 0.0000000018210954905465063 Scatter Plot
Source VCAM Source THY1 THY1 Cell-Cell Contact 0.2939 0.00000000002038348056610372 Scatter Plot
Source VCAM Source TWEAK TWEAK Secreted Signaling 0.3018 0.000000000005466838099704386 Scatter Plot
Target VCAM Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.3095 0.0000000000014668830229205742 Scatter Plot
Target VCAM Target VEGF VEGF Secreted Signaling 0.3103 0.0000000000012795698831952654 Scatter Plot
Source VCAM Source FGF FGF Secreted Signaling 0.3121 0.0000000000009230981069295185 Scatter Plot
Target VCAM Source BAFF BAFF Secreted Signaling 0.3163 0.00000000000044550513142347423 Scatter Plot
Target VCAM Source LAIR1 LAIR1 Cell-Cell Contact 0.3371 0.000000000000009447519552629608 Scatter Plot
Source VCAM Source EPHB EPHB Cell-Cell Contact 0.3379 0.000000000000007994960124894671 Scatter Plot
Source VCAM Source COLLAGEN COLLAGEN ECM-Receptor 0.3397 0.000000000000005735393193772145 Scatter Plot
Target VCAM Source SELL SELL Cell-Cell Contact 0.3414 0.000000000000004118817531315033 Scatter Plot
Target VCAM Source APP APP Cell-Cell Contact 0.3460 0.0000000000000016383457301780602 Scatter Plot
Target VCAM Target ICAM ICAM Cell-Cell Contact 0.3689 0.000000000000000014516911893364393 Scatter Plot
Target VCAM Target COMPLEMENT COMPLEMENT Secreted Signaling 0.3728 0.000000000000000006140016548024485 Scatter Plot
Source VCAM Source ANGPT ANGPT Secreted Signaling 0.3796 0.0000000000000000013678420443739308 Scatter Plot
Target VCAM Source PARs PARs Secreted Signaling 0.3806 0.000000000000000001102999901088683 Scatter Plot
Source VCAM Source GALECTIN GALECTIN Secreted Signaling 0.3830 0.0000000000000000006474730073638955 Scatter Plot
Target VCAM Source CD52 CD52 Cell-Cell Contact 0.4325 0.0000000000000000000000033033296300027256 Scatter Plot
Target VCAM Target CEACAM CEACAM Cell-Cell Contact 0.4396 0.00000000000000000000000048119263689628775 Scatter Plot
Target VCAM Source NCAM NCAM Cell-Cell Contact 0.4408 0.0000000000000000000000003469455067137742 Scatter Plot
Target VCAM Source VISTA VISTA Cell-Cell Contact 0.4409 0.0000000000000000000000003348177086182008 Scatter Plot
Target VCAM Source SEMA4 SEMA4 Cell-Cell Contact 0.4465 0.00000000000000000000000007078631855452625 Scatter Plot
Source VCAM Source MHC-II MHC-II Cell-Cell Contact 0.4572 0.000000000000000000000000003383597098858367 Scatter Plot
Target VCAM Source ANNEXIN ANNEXIN Secreted Signaling 0.4908 0.000000000000000000000000000000113501350166461 Scatter Plot
Target VCAM Source COMPLEMENT COMPLEMENT Secreted Signaling 0.5606 0.0000000000000000000000000000000000000000009802976443479199 Scatter Plot
Target VCAM Target CD34 CD34 Cell-Cell Contact -0.4430 0.00000000000000000000000018948877650121423 Scatter Plot
Target VCAM Source MHC-I MHC-I Cell-Cell Contact -0.4167 0.00000000000000000000019771283790053401 Scatter Plot
Target VCAM Target SEMA7 SEMA7 Cell-Cell Contact -0.4158 0.00000000000000000000025351053412818586 Scatter Plot
Source VCAM Source VISTA VISTA Cell-Cell Contact -0.4068 0.00000000000000000000233909406379674 Scatter Plot
Target VCAM Source BST2 BST2 Cell-Cell Contact -0.4017 0.000000000000000000008180559558323671 Scatter Plot
Target VCAM Source ANGPT ANGPT Secreted Signaling -0.3960 0.000000000000000000031997457620515024 Scatter Plot
Target VCAM Source MHC-II MHC-II Cell-Cell Contact -0.3954 0.000000000000000000036636733004763505 Scatter Plot
Source VCAM Source NCAM NCAM Cell-Cell Contact -0.3951 0.0000000000000000000389942034287838 Scatter Plot
Target VCAM Target MK MK Secreted Signaling -0.3928 0.00000000000000000006815402276221431 Scatter Plot
Target VCAM Target TENASCIN TENASCIN ECM-Receptor -0.3689 0.000000000000000014479309825149705 Scatter Plot
Target VCAM Source JAM JAM Cell-Cell Contact -0.3632 0.00000000000000004867528413575434 Scatter Plot
Target VCAM Target SEMA4 SEMA4 Cell-Cell Contact -0.3630 0.000000000000000050797200085877684 Scatter Plot
Target VCAM Target PTN PTN Secreted Signaling -0.3627 0.000000000000000053740434073471725 Scatter Plot
Target VCAM Target KIT KIT Secreted Signaling -0.3560 0.00000000000000021950209376868711 Scatter Plot
Source VCAM Source SEMA4 SEMA4 Cell-Cell Contact -0.3481 0.0000000000000010769317322524436 Scatter Plot
Target VCAM Target VWF VWF ECM-Receptor -0.3458 0.0000000000000017293449685165933 Scatter Plot
Target VCAM Target CD39 CD39 Cell-Cell Contact -0.3450 0.000000000000002005670249695904 Scatter Plot
Target VCAM Target ncWNT ncWNT Secreted Signaling -0.3254 0.00000000000008477542899644388 Scatter Plot
Target VCAM Source TWEAK TWEAK Secreted Signaling -0.3250 0.00000000000009213595200841873 Scatter Plot
Target VCAM Source ESAM ESAM Cell-Cell Contact -0.3107 0.0000000000011905487722669378 Scatter Plot
Target VCAM Target ESAM ESAM Cell-Cell Contact -0.3107 0.0000000000011905487722669594 Scatter Plot
Target VCAM Target FGF FGF Secreted Signaling -0.3099 0.0000000000013634989303991042 Scatter Plot
Target VCAM Target JAM JAM Cell-Cell Contact -0.3064 0.0000000000024740439521368 Scatter Plot
Target VCAM Source EPHB EPHB Cell-Cell Contact -0.3058 0.0000000000027445111546010256 Scatter Plot
Target VCAM Source LIFR LIFR Secreted Signaling -0.2953 0.00000000001602890658222448 Scatter Plot
Target VCAM Target WNT WNT Secreted Signaling -0.2939 0.00000000002017539526402808 Scatter Plot
Target VCAM Target FN1 FN1 ECM-Receptor -0.2932 0.000000000022831215590617388 Scatter Plot
Target VCAM Source PSAP PSAP Secreted Signaling -0.2925 0.00000000002527929283031589 Scatter Plot
Target VCAM Source GALECTIN GALECTIN Secreted Signaling -0.2924 0.000000000025804504902429013 Scatter Plot
Target VCAM Source COLLAGEN COLLAGEN ECM-Receptor -0.2923 0.00000000002628977355987428 Scatter Plot
Target VCAM Source CD34 CD34 Cell-Cell Contact -0.2915 0.000000000029681655569800716 Scatter Plot
Target VCAM Source ICAM ICAM Cell-Cell Contact -0.2898 0.00000000003923167174072317 Scatter Plot
Target VCAM Source FLT3 FLT3 Secreted Signaling -0.2883 0.000000000050051988677573245 Scatter Plot
Target VCAM Target VTN VTN ECM-Receptor -0.2876 0.000000000055554534778703827 Scatter Plot
Target VCAM Target SLURP SLURP Secreted Signaling -0.2809 0.0000000001614786237200064 Scatter Plot
Target VCAM Source PROS PROS Secreted Signaling -0.2650 0.000000001768463064051273 Scatter Plot
Target VCAM Source LCK LCK Cell-Cell Contact -0.2602 0.0000000035005217016151772 Scatter Plot
Target VCAM Source IL7 IL7 Secreted Signaling -0.2572 0.000000005374133919794726 Scatter Plot
Target VCAM Target SPP1 SPP1 Secreted Signaling -0.2521 0.00000001088212341092964 Scatter Plot
Target VCAM Source BMP BMP Secreted Signaling -0.2459 0.000000025235663440857177 Scatter Plot
Target VCAM Source CD46 CD46 Cell-Cell Contact -0.2448 0.000000029479364560227395 Scatter Plot
Target VCAM Source SEMA7 SEMA7 Cell-Cell Contact -0.2434 0.000000035367877094396985 Scatter Plot
Target VCAM Target DMP1 DMP1 ECM-Receptor -0.2419 0.00000004309211184234208 Scatter Plot
Target VCAM Target APP APP Cell-Cell Contact -0.2394 0.00000006014212312541002 Scatter Plot
Target VCAM Target MIF MIF Secreted Signaling -0.2370 0.00000008161597395718826 Scatter Plot
Target VCAM Target EPHB EPHB Cell-Cell Contact -0.2369 0.00000008274279073775461 Scatter Plot
Target VCAM Target IGF IGF Secreted Signaling -0.2329 0.0000001386701005617836 Scatter Plot
Target VCAM Source GP1BA GP1BA Cell-Cell Contact -0.2282 0.0000002498531978296803 Scatter Plot
Target VCAM Target NPR2 NPR2 Secreted Signaling -0.2273 0.0000002778558129655009 Scatter Plot
Target VCAM Target BSP BSP ECM-Receptor -0.2251 0.0000003669029325246554 Scatter Plot
Target VCAM Target NOTCH NOTCH Cell-Cell Contact -0.2241 0.00000041065691043734393 Scatter Plot
Target VCAM Target THBS THBS ECM-Receptor -0.2215 0.0000005652564106851386 Scatter Plot
Target VCAM Target SEMA5 SEMA5 Cell-Cell Contact -0.2182 0.0000008332326916198376 Scatter Plot
Target VCAM Source PDGF PDGF Secreted Signaling -0.2182 0.0000008367202538429615 Scatter Plot
Target VCAM Target ANGPTL ANGPTL Secreted Signaling -0.2180 0.0000008592687752409719 Scatter Plot
Target VCAM Target LAMININ LAMININ ECM-Receptor -0.2164 0.0000010395099086127575 Scatter Plot
Target VCAM Target PERIOSTIN PERIOSTIN Secreted Signaling -0.2155 0.0000011494172780319776 Scatter Plot
Target VCAM Source CXCL CXCL Secreted Signaling -0.2148 0.0000012541843059772104 Scatter Plot
Target VCAM Target TGFb TGFb Secreted Signaling -0.2145 0.0000012957895102441437 Scatter Plot
Target VCAM Target AGT AGT Secreted Signaling -0.2136 0.0000014333268933916203 Scatter Plot
Target VCAM Source GAS GAS Secreted Signaling -0.2133 0.0000014830708565312737 Scatter Plot
Source VCAM Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.2111 0.000001910895500051915 Scatter Plot
Target VCAM Target VEGF VEGF Secreted Signaling -0.2060 0.000003412078447738807 Scatter Plot
Source VCAM Source SPP1 SPP1 Secreted Signaling -0.2047 0.00000394354974260523 Scatter Plot
Target VCAM Source THY1 THY1 Cell-Cell Contact -0.2023 0.000005146801063517808 Scatter Plot
Target VCAM Target ACTIVIN ACTIVIN Secreted Signaling -0.2016 0.000005542716698137834 Scatter Plot
Target VCAM Source NT NT Secreted Signaling -0.1957 0.00001049239481834828 Scatter Plot
Target VCAM Source OSM OSM Secreted Signaling -0.1952 0.000011038791956611674 Scatter Plot
Target VCAM Target VISFATIN VISFATIN Secreted Signaling -0.1879 0.000023378449758866715 Scatter Plot
Target VCAM Target SEMA6 SEMA6 Cell-Cell Contact -0.1851 0.00003107170984768352 Scatter Plot
Target VCAM Source IL2 IL2 Secreted Signaling -0.1824 0.00004064279912425612 Scatter Plot
Target VCAM Source CDH CDH Cell-Cell Contact -0.1816 0.00004426211949557312 Scatter Plot
Target VCAM Target CDH CDH Cell-Cell Contact -0.1816 0.00004426211949557312 Scatter Plot
Target VCAM Source VEGF VEGF Secreted Signaling -0.1716 0.0001147348601352 Scatter Plot
Source VCAM Source MIF MIF Secreted Signaling -0.1678 0.0001629090765939 Scatter Plot
Target VCAM Source CCL CCL Secreted Signaling -0.1676 0.0001662179521573 Scatter Plot
Target VCAM Source CD86 CD86 Cell-Cell Contact -0.1646 0.0002184841432486 Scatter Plot
Target VCAM Target PECAM1 PECAM1 Cell-Cell Contact -0.1646 0.0002190018370772 Scatter Plot
Target VCAM Source PECAM1 PECAM1 Cell-Cell Contact -0.1646 0.0002190018370772 Scatter Plot
Target VCAM Target CADM CADM Cell-Cell Contact -0.1598 0.0003328195371081 Scatter Plot
Target VCAM Source CADM CADM Cell-Cell Contact -0.1598 0.0003328195371081 Scatter Plot
Target VCAM Target BMP BMP Secreted Signaling -0.1573 0.0004135171375136 Scatter Plot
Target VCAM Target TWEAK TWEAK Secreted Signaling -0.1544 0.0005309604968341 Scatter Plot
Target VCAM Source FGF FGF Secreted Signaling -0.1507 0.0007248607734012 Scatter Plot
Target VCAM Source RANKL RANKL Secreted Signaling -0.1498 0.000776181265977 Scatter Plot
Target VCAM Source LAMININ LAMININ ECM-Receptor -0.1494 0.0008071488703477 Scatter Plot
Target VCAM Source LIGHT LIGHT Secreted Signaling -0.1492 0.0008181166753564 Scatter Plot
Target VCAM Source CSF CSF Secreted Signaling -0.1473 0.0009550163040576 Scatter Plot
Target VCAM Source MK MK Secreted Signaling -0.1442 0.0012255863084584 Scatter Plot
Target VCAM Target CD200 CD200 Cell-Cell Contact -0.1378 0.0020124709013593 Scatter Plot
Target VCAM Source TGFb TGFb Secreted Signaling -0.1371 0.0021163401448097 Scatter Plot
Target VCAM Source SEMA4 SEMA4 Cell-Cell Contact -0.1355 0.0023894790348774 Scatter Plot
Target VCAM Source CD45 CD45 Cell-Cell Contact -0.1269 0.0044984127607262 Scatter Plot
Target VCAM Target GAS GAS Secreted Signaling -0.1264 0.0046378258553207 Scatter Plot
Source VCAM Source CLEC CLEC Cell-Cell Contact -0.1247 0.0052191839370613 Scatter Plot
Target VCAM Source PTN PTN Secreted Signaling -0.1204 0.0070086664370988 Scatter Plot
Target VCAM Target ADIPONECTIN ADIPONECTIN Secreted Signaling -0.1154 0.009799988727144 Scatter Plot
Target VCAM Source ncWNT ncWNT Secreted Signaling -0.1146 0.0103127334986093 Scatter Plot
Target VCAM Target COLLAGEN COLLAGEN ECM-Receptor -0.1142 0.0105944545201867 Scatter Plot
Target VCAM Source APELIN APELIN Secreted Signaling -0.1128 0.0115909282089255 Scatter Plot
Target VCAM Source GDF GDF Secreted Signaling -0.1018 0.0227908808185105 Scatter Plot
Target VCAM Source CX3C CX3C Secreted Signaling -0.0986 0.0274391079319247 Scatter Plot
Target VCAM Target PDGF PDGF Secreted Signaling -0.0965 0.0308859880211292 Scatter Plot
Source VCAM Source LAMININ LAMININ ECM-Receptor 0.0962 0.031547625270343 Scatter Plot
Source VCAM Source AGRN AGRN ECM-Receptor 0.1013 0.023558484585903 Scatter Plot
Source VCAM Source SEMA3 SEMA3 Secreted Signaling 0.1040 0.0200755359908469 Scatter Plot
Source VCAM Target EPHA EPHA Cell-Cell Contact 0.1138 0.0108459189928078 Scatter Plot
Source VCAM Source PTN PTN Secreted Signaling 0.1140 0.0107234168855123 Scatter Plot
Source VCAM Target CADM CADM Cell-Cell Contact 0.1143 0.0105655723988841 Scatter Plot
Source VCAM Target GALECTIN GALECTIN Secreted Signaling 0.1153 0.009848840581567 Scatter Plot
Source VCAM Target PECAM1 PECAM1 Cell-Cell Contact 0.1165 0.0091084151780113 Scatter Plot
Source VCAM Source PECAM1 PECAM1 Cell-Cell Contact 0.1165 0.0091084151780113 Scatter Plot
Target VCAM Target GRN GRN Secreted Signaling 0.1175 0.0085520903908347 Scatter Plot
Source VCAM Target IL6 IL6 Secreted Signaling 0.1304 0.0034843792124208 Scatter Plot
Source VCAM Target VEGF VEGF Secreted Signaling 0.1313 0.0032615823390947 Scatter Plot
Source VCAM Target LAIR1 LAIR1 Cell-Cell Contact 0.1324 0.0030196669163499 Scatter Plot
Source VCAM Target BST2 BST2 Cell-Cell Contact 0.1324 0.0030196669163498 Scatter Plot
Source VCAM Target CDH CDH Cell-Cell Contact 0.1414 0.0015218320088133 Scatter Plot
Source VCAM Target NODAL NODAL Secreted Signaling 0.1437 0.001271578806783 Scatter Plot
Source VCAM Target BMP BMP Secreted Signaling 0.1576 0.000402685397863 Scatter Plot
Source VCAM Target RANKL RANKL Secreted Signaling 0.1608 0.0003050935974706 Scatter Plot
Source VCAM Source SEMA4 SEMA4 Cell-Cell Contact 0.1622 0.0002701641269023 Scatter Plot
Source VCAM Source IL16 IL16 Secreted Signaling 0.1628 0.0002558537710624 Scatter Plot
Source VCAM Target GDF GDF Secreted Signaling 0.1700 0.0001334486569454 Scatter Plot
Source VCAM Source MK MK Secreted Signaling 0.1755 0.00007937925518844935 Scatter Plot
Source VCAM Target PERIOSTIN PERIOSTIN Secreted Signaling 0.1805 0.00004913791320255051 Scatter Plot
Source VCAM Target BSP BSP ECM-Receptor 0.1814 0.00004521102546130109 Scatter Plot
Source VCAM Target NOTCH NOTCH Cell-Cell Contact 0.1815 0.000044734632375303166 Scatter Plot
Source VCAM Target IL1 IL1 Secreted Signaling 0.1850 0.00003158137613228444 Scatter Plot
Source VCAM Target SEMA5 SEMA5 Cell-Cell Contact 0.1870 0.000025645769294502195 Scatter Plot
Source VCAM Target DMP1 DMP1 ECM-Receptor 0.1889 0.00002119627231149041 Scatter Plot
Source VCAM Target SEMA6 SEMA6 Cell-Cell Contact 0.1910 0.000017117066485422506 Scatter Plot
Source VCAM Source GP1BA GP1BA Cell-Cell Contact 0.1930 0.00001387602765165912 Scatter Plot
Source VCAM Target SELL SELL Cell-Cell Contact 0.1988 0.000007472519653550616 Scatter Plot
Target VCAM Target CLEC CLEC Cell-Cell Contact 0.2020 0.000005323718758236706 Scatter Plot
Source VCAM Target CD34 CD34 Cell-Cell Contact 0.2021 0.000005241855092090585 Scatter Plot
Source VCAM Target NPR2 NPR2 Secreted Signaling 0.2021 0.000005227009951007752 Scatter Plot
Target VCAM Target CD23 CD23 Cell-Cell Contact 0.2026 0.000004954370882513306 Scatter Plot
Source VCAM Source VEGF VEGF Secreted Signaling 0.2040 0.00000423508493101247 Scatter Plot
Source VCAM Source CCL CCL Secreted Signaling 0.2045 0.000004006969395939337 Scatter Plot
Source VCAM Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.2052 0.0000037341615571658672 Scatter Plot
Source VCAM Target EPHB EPHB Cell-Cell Contact 0.2060 0.0000034207464058178143 Scatter Plot
Target VCAM Target THY1 THY1 Cell-Cell Contact 0.2082 0.00000265038514284752 Scatter Plot
Source VCAM Target ACTIVIN ACTIVIN Secreted Signaling 0.2097 0.0000022489246925853192 Scatter Plot
Source VCAM Source IL2 IL2 Secreted Signaling 0.2113 0.0000018639049589562227 Scatter Plot
Source VCAM Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2119 0.0000017375449217596629 Scatter Plot
Source VCAM Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2141 0.000001357786745394634 Scatter Plot
Source VCAM Target NRG NRG Secreted Signaling 0.2216 0.0000005552755175259004 Scatter Plot
Source VCAM Target CD22 CD22 Cell-Cell Contact 0.2345 0.0000001123440234155468 Scatter Plot
Source VCAM Target VWF VWF ECM-Receptor 0.2348 0.00000010880825118219456 Scatter Plot
Target VCAM Target IL1 IL1 Secreted Signaling 0.2350 0.0000001053467112414644 Scatter Plot
Source VCAM Target CD200 CD200 Cell-Cell Contact 0.2353 0.00000010227506571296789 Scatter Plot
Source VCAM Target PDGF PDGF Secreted Signaling 0.2378 0.00000007341310421755344 Scatter Plot
Source VCAM Target BAFF BAFF Secreted Signaling 0.2432 0.000000036256313984577864 Scatter Plot
Source VCAM Source GAS GAS Secreted Signaling 0.2479 0.0000000193060208611252 Scatter Plot
Source VCAM Target ESAM ESAM Cell-Cell Contact 0.2496 0.000000015383612610343023 Scatter Plot
Source VCAM Source ESAM ESAM Cell-Cell Contact 0.2496 0.000000015383612610343023 Scatter Plot
Source VCAM Target PTN PTN Secreted Signaling 0.2502 0.00000001421889788135388 Scatter Plot
Target VCAM Target ANNEXIN ANNEXIN Secreted Signaling 0.2517 0.00000001157701311767712 Scatter Plot
Source VCAM Target FGF FGF Secreted Signaling 0.2735 0.0000000005004758539365776 Scatter Plot
Target VCAM Target CCL CCL Secreted Signaling 0.2777 0.0000000002628476502245705 Scatter Plot
Source VCAM Target SLURP SLURP Secreted Signaling 0.2820 0.00000000013632968413418222 Scatter Plot
Source VCAM Target IGF IGF Secreted Signaling 0.2828 0.00000000011915741495193222 Scatter Plot
Source VCAM Source LCK LCK Cell-Cell Contact 0.2880 0.00000000005246267334360346 Scatter Plot
Source VCAM Source ICAM ICAM Cell-Cell Contact 0.3082 0.000000000001837585734091693 Scatter Plot
Source VCAM Target APP APP Cell-Cell Contact 0.3100 0.0000000000013346305021345697 Scatter Plot
Source VCAM Target SEMA4 SEMA4 Cell-Cell Contact 0.3164 0.00000000000043570294612709 Scatter Plot
Source VCAM Target MIF MIF Secreted Signaling 0.3303 0.000000000000034459057177793924 Scatter Plot
Source VCAM Target ncWNT ncWNT Secreted Signaling 0.3313 0.000000000000028142551426414242 Scatter Plot
Source VCAM Target WNT WNT Secreted Signaling 0.3314 0.0000000000000277553432303951 Scatter Plot
Source VCAM Source CD86 CD86 Cell-Cell Contact 0.3345 0.000000000000015572344447252775 Scatter Plot
Target VCAM Target IFN-II IFN-II Secreted Signaling 0.3455 0.0000000000000018194461717732867 Scatter Plot
Source VCAM Target TGFb TGFb Secreted Signaling 0.3597 0.00000000000000010232955012862021 Scatter Plot
Source VCAM Target CD39 CD39 Cell-Cell Contact 0.3760 0.0000000000000000030742430893052336 Scatter Plot
Source VCAM Target PARs PARs Secreted Signaling 0.4056 0.000000000000000000003204981411971569 Scatter Plot
Target VCAM Target VEGF VEGF Secreted Signaling 0.4184 0.00000000000000000000012856031861818041 Scatter Plot
Target VCAM Target CD52 CD52 Cell-Cell Contact 0.4460 0.00000000000000000000000008063819105862722 Scatter Plot
Source VCAM Source MHC-I MHC-I Cell-Cell Contact 0.4689 0.00000000000000000000000000010426113391040896 Scatter Plot
Source VCAM Target KIT KIT Secreted Signaling 0.4868 0.0000000000000000000000000000004003892404712156 Scatter Plot
Target VCAM Target PARs PARs Secreted Signaling -0.4719 0.0000000000000000000000000000421933225430266 Scatter Plot
Source VCAM Source VISTA VISTA Cell-Cell Contact -0.4709 0.0000000000000000000000000000570652553220744 Scatter Plot
Source VCAM Source COMPLEMENT COMPLEMENT Secreted Signaling -0.4698 0.00000000000000000000000000007943348457893574 Scatter Plot
Source VCAM Source APP APP Cell-Cell Contact -0.4230 0.00000000000000000000003960889167283218 Scatter Plot
Source VCAM Target CEACAM CEACAM Cell-Cell Contact -0.3421 0.000000000000003534408879142559 Scatter Plot
Source VCAM Source PARs PARs Secreted Signaling -0.3345 0.000000000000015567108788570084 Scatter Plot
Source VCAM Target CD52 CD52 Cell-Cell Contact -0.3208 0.00000000000019700130531344206 Scatter Plot
Target VCAM Target SELL SELL Cell-Cell Contact -0.3113 0.0000000000010667322335821957 Scatter Plot
Source VCAM Source ANNEXIN ANNEXIN Secreted Signaling -0.3011 0.00000000000611969155290886 Scatter Plot
Source VCAM Source SELL SELL Cell-Cell Contact -0.2915 0.00000000003002676940156594 Scatter Plot
Source VCAM Source GRN GRN Secreted Signaling -0.2748 0.000000000407939479628518 Scatter Plot
Source VCAM Source CD52 CD52 Cell-Cell Contact -0.2720 0.0000000006233759733371319 Scatter Plot
Target VCAM Target ANGPT ANGPT Secreted Signaling -0.2718 0.0000000006463727370091735 Scatter Plot
Target VCAM Target NRG NRG Secreted Signaling -0.2517 0.000000011470545137828832 Scatter Plot
Source VCAM Source BAFF BAFF Secreted Signaling -0.2471 0.000000021651555293500693 Scatter Plot
Target VCAM Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.2452 0.00000002786336803025945 Scatter Plot
Source VCAM Target CCL CCL Secreted Signaling -0.2433 0.000000035883935929665466 Scatter Plot
Source VCAM Target CLEC CLEC Cell-Cell Contact -0.2405 0.000000052042278313159846 Scatter Plot
Source VCAM Target CSF CSF Secreted Signaling -0.2398 0.00000005688875667762725 Scatter Plot
Source VCAM Target NCAM NCAM Cell-Cell Contact -0.2357 0.00000009691676960770341 Scatter Plot
Target VCAM Target IL6 IL6 Secreted Signaling -0.2265 0.0000003088104662806152 Scatter Plot
Source VCAM Source LAIR1 LAIR1 Cell-Cell Contact -0.2170 0.000000963356063531425 Scatter Plot
Source VCAM Target ICAM ICAM Cell-Cell Contact -0.2150 0.000001221979719488215 Scatter Plot
Source VCAM Target SELPLG SELPLG Cell-Cell Contact -0.2123 0.000001658350970786617 Scatter Plot
Source VCAM Target VEGF VEGF Secreted Signaling -0.2024 0.000005061028346913459 Scatter Plot
Source VCAM Target CXCL CXCL Secreted Signaling -0.1968 0.00000930472505960203 Scatter Plot
Target VCAM Target VISFATIN VISFATIN Secreted Signaling -0.1879 0.000023402692306027 Scatter Plot
Source VCAM Target IL17 IL17 Secreted Signaling -0.1808 0.00004783333818212654 Scatter Plot
Target VCAM Target BAFF BAFF Secreted Signaling -0.1774 0.00006650640137132599 Scatter Plot
Source VCAM Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1769 0.0000695619907972029 Scatter Plot
Source VCAM Target SEMA3 SEMA3 Secreted Signaling -0.1764 0.00007347064070104593 Scatter Plot
Source VCAM Target ANNEXIN ANNEXIN Secreted Signaling -0.1756 0.00007911075939974554 Scatter Plot
Source VCAM Target IFN-II IFN-II Secreted Signaling -0.1716 0.000115447204843 Scatter Plot
Source VCAM Target GRN GRN Secreted Signaling -0.1704 0.0001291429938901 Scatter Plot
Target VCAM Target OSM OSM Secreted Signaling -0.1283 0.0040683939331689 Scatter Plot
Target VCAM Target CD22 CD22 Cell-Cell Contact -0.1269 0.0044984127607262 Scatter Plot
Source VCAM Target IL1 IL1 Secreted Signaling -0.1253 0.0050255693164179 Scatter Plot
Source VCAM Target THY1 THY1 Cell-Cell Contact -0.1240 0.0054907201472881 Scatter Plot
Source VCAM Source CCL CCL Secreted Signaling -0.1193 0.0075692329505624 Scatter Plot
Source VCAM Source TNF TNF Secreted Signaling -0.1091 0.014697353305816 Scatter Plot
Source VCAM Source SEMA6 SEMA6 Cell-Cell Contact -0.1085 0.0151968343655966 Scatter Plot
Source VCAM Target CD23 CD23 Cell-Cell Contact -0.1057 0.0180550654283305 Scatter Plot

Cells that are targets of VCAM from HSCs*

Cells that are source of VCAM to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.