Pathway: ITGAL-ITGB2

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Cell-Cell Contact

Details on the ITGAL-ITGB2 pathway:

Specificity Index HSPC as target: 0.597
HSPC as source: 0.491

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the ITGAL-ITGB2 pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target ITGAL-ITGB2 Source MIF MIF Secreted Signaling 0.0966 0.0308415575764119 Scatter Plot
Target ITGAL-ITGB2 Source SEMA6 SEMA6 Cell-Cell Contact 0.0981 0.0283562949752528 Scatter Plot
Target ITGAL-ITGB2 Source NT NT Secreted Signaling 0.0982 0.0281896419071433 Scatter Plot
Source ITGAL-ITGB2 Source ANGPTL ANGPTL Secreted Signaling 0.0994 0.026316001274936 Scatter Plot
Target ITGAL-ITGB2 Source CX3C CX3C Secreted Signaling 0.1020 0.0226095205305136 Scatter Plot
Target ITGAL-ITGB2 Source WNT WNT Secreted Signaling 0.1032 0.0210539523019555 Scatter Plot
Target ITGAL-ITGB2 Source CD46 CD46 Cell-Cell Contact 0.1038 0.020314351968112 Scatter Plot
Source ITGAL-ITGB2 Source MIF MIF Secreted Signaling 0.1040 0.0199794837044466 Scatter Plot
Target ITGAL-ITGB2 Source LIGHT LIGHT Secreted Signaling 0.1067 0.0170481531825035 Scatter Plot
Target ITGAL-ITGB2 Target VEGF VEGF Secreted Signaling 0.1079 0.0157477758681695 Scatter Plot
Target ITGAL-ITGB2 Source CD1D2 CD1D2 Cell-Cell Contact 0.1092 0.0145857554350285 Scatter Plot
Target ITGAL-ITGB2 Target CCL CCL Secreted Signaling 0.1141 0.0106739411962967 Scatter Plot
Target ITGAL-ITGB2 Target TWEAK TWEAK Secreted Signaling 0.1167 0.0090110861465126 Scatter Plot
Target ITGAL-ITGB2 Source EPHB EPHB Cell-Cell Contact 0.1167 0.008999450377356 Scatter Plot
Target ITGAL-ITGB2 Target AGT AGT Secreted Signaling 0.1171 0.0087601349002574 Scatter Plot
Target ITGAL-ITGB2 Target GDF GDF Secreted Signaling 0.1201 0.0071929646840681 Scatter Plot
Target ITGAL-ITGB2 Source FLT3 FLT3 Secreted Signaling 0.1215 0.0065309383288787 Scatter Plot
Target ITGAL-ITGB2 Target IGF IGF Secreted Signaling 0.1229 0.0059468473425528 Scatter Plot
Target ITGAL-ITGB2 Target CD200 CD200 Cell-Cell Contact 0.1247 0.0052288485841441 Scatter Plot
Target ITGAL-ITGB2 Source RANKL RANKL Secreted Signaling 0.1283 0.0040611563881749 Scatter Plot
Source ITGAL-ITGB2 Source VISFATIN VISFATIN Secreted Signaling 0.1297 0.0036708394010539 Scatter Plot
Target ITGAL-ITGB2 Source CSF CSF Secreted Signaling 0.1318 0.003139910683075 Scatter Plot
Target ITGAL-ITGB2 Source CXCL CXCL Secreted Signaling 0.1325 0.0030033704532666 Scatter Plot
Target ITGAL-ITGB2 Source GDF GDF Secreted Signaling 0.1329 0.0029090626462862 Scatter Plot
Target ITGAL-ITGB2 Source MK MK Secreted Signaling 0.1331 0.0028686021564598 Scatter Plot
Target ITGAL-ITGB2 Target THBS THBS ECM-Receptor 0.1377 0.0020209582249732 Scatter Plot
Target ITGAL-ITGB2 Target CADM CADM Cell-Cell Contact 0.1404 0.0016436610687975 Scatter Plot
Target ITGAL-ITGB2 Source CADM CADM Cell-Cell Contact 0.1404 0.0016436610687975 Scatter Plot
Target ITGAL-ITGB2 Target BSP BSP ECM-Receptor 0.1428 0.0013622513458197 Scatter Plot
Target ITGAL-ITGB2 Source PTN PTN Secreted Signaling 0.1476 0.0009281725137871 Scatter Plot
Target ITGAL-ITGB2 Target PERIOSTIN PERIOSTIN Secreted Signaling 0.1492 0.0008185277791051 Scatter Plot
Target ITGAL-ITGB2 Source THY1 THY1 Cell-Cell Contact 0.1501 0.0007573466427345 Scatter Plot
Target ITGAL-ITGB2 Target DMP1 DMP1 ECM-Receptor 0.1501 0.0007565955626574 Scatter Plot
Target ITGAL-ITGB2 Source ANGPTL ANGPTL Secreted Signaling 0.1515 0.000673967192739 Scatter Plot
Target ITGAL-ITGB2 Source IL7 IL7 Secreted Signaling 0.1526 0.0006191008653094 Scatter Plot
Target ITGAL-ITGB2 Source APELIN APELIN Secreted Signaling 0.1569 0.0004297564805798 Scatter Plot
Target ITGAL-ITGB2 Source SEMA7 SEMA7 Cell-Cell Contact 0.1571 0.0004202112870101 Scatter Plot
Target ITGAL-ITGB2 Target TGFb TGFb Secreted Signaling 0.1593 0.0003486115505081 Scatter Plot
Target ITGAL-ITGB2 Target PDGF PDGF Secreted Signaling 0.1596 0.0003383815962773 Scatter Plot
Target ITGAL-ITGB2 Source PDGF PDGF Secreted Signaling 0.1597 0.000335667203466 Scatter Plot
Target ITGAL-ITGB2 Target MIF MIF Secreted Signaling 0.1612 0.0002943854668951 Scatter Plot
Target ITGAL-ITGB2 Target COLLAGEN COLLAGEN ECM-Receptor 0.1613 0.0002923119010396 Scatter Plot
Target ITGAL-ITGB2 Source CD34 CD34 Cell-Cell Contact 0.1614 0.0002907263894296 Scatter Plot
Target ITGAL-ITGB2 Source IL2 IL2 Secreted Signaling 0.1615 0.0002876724530312 Scatter Plot
Target ITGAL-ITGB2 Target NPR2 NPR2 Secreted Signaling 0.1619 0.000276928111492 Scatter Plot
Target ITGAL-ITGB2 Source NOTCH NOTCH Cell-Cell Contact 0.1644 0.0002225403473063 Scatter Plot
Target ITGAL-ITGB2 Target VISFATIN VISFATIN Secreted Signaling 0.1652 0.0002066467164686 Scatter Plot
Target ITGAL-ITGB2 Target ANGPTL ANGPTL Secreted Signaling 0.1656 0.0002005109502289 Scatter Plot
Target ITGAL-ITGB2 Target EPHB EPHB Cell-Cell Contact 0.1681 0.0001591881425099 Scatter Plot
Source ITGAL-ITGB2 Source IL1 IL1 Secreted Signaling 0.1694 0.0001406805063114 Scatter Plot
Target ITGAL-ITGB2 Source LAMININ LAMININ ECM-Receptor 0.1747 0.00008562870174309667 Scatter Plot
Target ITGAL-ITGB2 Source PROS PROS Secreted Signaling 0.1749 0.00008416178943531555 Scatter Plot
Target ITGAL-ITGB2 Target APP APP Cell-Cell Contact 0.1781 0.00006234745982317717 Scatter Plot
Target ITGAL-ITGB2 Source CCL CCL Secreted Signaling 0.1893 0.000020406069495985105 Scatter Plot
Target ITGAL-ITGB2 Source PSAP PSAP Secreted Signaling 0.1911 0.000016877585250201445 Scatter Plot
Target ITGAL-ITGB2 Source GAS GAS Secreted Signaling 0.1949 0.000011399233489204512 Scatter Plot
Target ITGAL-ITGB2 Source TGFb TGFb Secreted Signaling 0.1960 0.000010125142724931736 Scatter Plot
Target ITGAL-ITGB2 Target SPP1 SPP1 Secreted Signaling 0.1971 0.000008965006329983648 Scatter Plot
Target ITGAL-ITGB2 Target FN1 FN1 ECM-Receptor 0.1981 0.00000808359204717299 Scatter Plot
Target ITGAL-ITGB2 Target CSPG4 CSPG4 Cell-Cell Contact 0.2013 0.00000573842638526432 Scatter Plot
Target ITGAL-ITGB2 Target SEMA6 SEMA6 Cell-Cell Contact 0.2022 0.000005198456985733155 Scatter Plot
Target ITGAL-ITGB2 Target PTN PTN Secreted Signaling 0.2045 0.00000400598023746483 Scatter Plot
Target ITGAL-ITGB2 Source COLLAGEN COLLAGEN ECM-Receptor 0.2060 0.000003410792737532002 Scatter Plot
Target ITGAL-ITGB2 Target ACTIVIN ACTIVIN Secreted Signaling 0.2068 0.000003120648061432336 Scatter Plot
Target ITGAL-ITGB2 Target SEMA5 SEMA5 Cell-Cell Contact 0.2084 0.000002605547033457592 Scatter Plot
Target ITGAL-ITGB2 Target SLURP SLURP Secreted Signaling 0.2099 0.000002183728020914347 Scatter Plot
Target ITGAL-ITGB2 Target FGF FGF Secreted Signaling 0.2102 0.000002129136666790804 Scatter Plot
Target ITGAL-ITGB2 Target BMP BMP Secreted Signaling 0.2103 0.0000020949268406293383 Scatter Plot
Target ITGAL-ITGB2 Target SEMA7 SEMA7 Cell-Cell Contact 0.2107 0.0000020120229956635923 Scatter Plot
Target ITGAL-ITGB2 Source VCAM VCAM Cell-Cell Contact 0.2119 0.0000017375449217596629 Scatter Plot
Target ITGAL-ITGB2 Target ANGPT ANGPT Secreted Signaling 0.2128 0.0000015734001623653687 Scatter Plot
Target ITGAL-ITGB2 Source BMP BMP Secreted Signaling 0.2171 0.0000009552994497579393 Scatter Plot
Target ITGAL-ITGB2 Target CD39 CD39 Cell-Cell Contact 0.2200 0.000000673799591556693 Scatter Plot
Target ITGAL-ITGB2 Target VTN VTN ECM-Receptor 0.2219 0.0000005364306784929794 Scatter Plot
Target ITGAL-ITGB2 Source FGF FGF Secreted Signaling 0.2263 0.0000003140926860421941 Scatter Plot
Target ITGAL-ITGB2 Target TENASCIN TENASCIN ECM-Receptor 0.2282 0.0000002477667174791555 Scatter Plot
Target ITGAL-ITGB2 Target CDH CDH Cell-Cell Contact 0.2307 0.0000001828371062236618 Scatter Plot
Target ITGAL-ITGB2 Source CDH CDH Cell-Cell Contact 0.2307 0.0000001828371062236618 Scatter Plot
Target ITGAL-ITGB2 Source GALECTIN GALECTIN Secreted Signaling 0.2325 0.00000014581711386919633 Scatter Plot
Target ITGAL-ITGB2 Source ESAM ESAM Cell-Cell Contact 0.2351 0.0000001049902790342326 Scatter Plot
Target ITGAL-ITGB2 Target ESAM ESAM Cell-Cell Contact 0.2351 0.0000001049902790342326 Scatter Plot
Source ITGAL-ITGB2 Source GRN GRN Secreted Signaling 0.2397 0.00000005740430951029469 Scatter Plot
Target ITGAL-ITGB2 Source ANGPT ANGPT Secreted Signaling 0.2424 0.000000040253461644587726 Scatter Plot
Source ITGAL-ITGB2 Source NCAM NCAM Cell-Cell Contact 0.2486 0.000000017515516262299095 Scatter Plot
Target ITGAL-ITGB2 Source TWEAK TWEAK Secreted Signaling 0.2502 0.000000014088202538059836 Scatter Plot
Target ITGAL-ITGB2 Target WNT WNT Secreted Signaling 0.2506 0.000000013448277259969097 Scatter Plot
Target ITGAL-ITGB2 Target ncWNT ncWNT Secreted Signaling 0.2535 0.000000009002486925866378 Scatter Plot
Target ITGAL-ITGB2 Target JAM JAM Cell-Cell Contact 0.2535 0.000000008993344220436955 Scatter Plot
Target ITGAL-ITGB2 Target KIT KIT Secreted Signaling 0.2554 0.000000006935725265762416 Scatter Plot
Target ITGAL-ITGB2 Source LCK LCK Cell-Cell Contact 0.2568 0.000000005714206480951303 Scatter Plot
Target ITGAL-ITGB2 Target MK MK Secreted Signaling 0.2575 0.000000005169084661640048 Scatter Plot
Target ITGAL-ITGB2 Target VWF VWF ECM-Receptor 0.2663 0.0000000014438827240467476 Scatter Plot
Target ITGAL-ITGB2 Source LIFR LIFR Secreted Signaling 0.2707 0.0000000007581719309300674 Scatter Plot
Target ITGAL-ITGB2 Source MHC-II MHC-II Cell-Cell Contact 0.2736 0.0000000004920367137142253 Scatter Plot
Target ITGAL-ITGB2 Source JAM JAM Cell-Cell Contact 0.2815 0.00000000014638916130830963 Scatter Plot
Target ITGAL-ITGB2 Target CD34 CD34 Cell-Cell Contact 0.2966 0.000000000013068193301819659 Scatter Plot
Target ITGAL-ITGB2 Source BST2 BST2 Cell-Cell Contact 0.2991 0.00000000000857069665585322 Scatter Plot
Target ITGAL-ITGB2 Source MHC-I MHC-I Cell-Cell Contact 0.3078 0.0000000000019630744723077656 Scatter Plot
Source ITGAL-ITGB2 Source PARs PARs Secreted Signaling 0.3735 0.0000000000000000053383115551337946 Scatter Plot
Source ITGAL-ITGB2 Source VISTA VISTA Cell-Cell Contact 0.4160 0.00000000000000000000023911319566074315 Scatter Plot
Source ITGAL-ITGB2 Source SELL SELL Cell-Cell Contact 0.5140 0.000000000000000000000000000000000045453161584662753 Scatter Plot
Source ITGAL-ITGB2 Source JAM JAM Cell-Cell Contact -0.5399 0.0000000000000000000000000000000000000035154219791766515 Scatter Plot
Source ITGAL-ITGB2 Source ESAM ESAM Cell-Cell Contact -0.5248 0.0000000000000000000000000000000000009566489365366877 Scatter Plot
Source ITGAL-ITGB2 Source ANGPT ANGPT Secreted Signaling -0.5058 0.0000000000000000000000000000000007566454113344624 Scatter Plot
Source ITGAL-ITGB2 Source BMP BMP Secreted Signaling -0.4925 0.00000000000000000000000000000006516009515581794 Scatter Plot
Source ITGAL-ITGB2 Source LIFR LIFR Secreted Signaling -0.4579 0.0000000000000000000000000027614637835238955 Scatter Plot
Source ITGAL-ITGB2 Source PDGF PDGF Secreted Signaling -0.4576 0.000000000000000000000000002945266889309236 Scatter Plot
Source ITGAL-ITGB2 Source TWEAK TWEAK Secreted Signaling -0.4261 0.000000000000000000000017905516207494065 Scatter Plot
Source ITGAL-ITGB2 Source SEMA7 SEMA7 Cell-Cell Contact -0.4220 0.00000000000000000000005120653921794042 Scatter Plot
Source ITGAL-ITGB2 Source IL7 IL7 Secreted Signaling -0.3650 0.00000000000000003351749304069813 Scatter Plot
Source ITGAL-ITGB2 Source NT NT Secreted Signaling -0.2924 0.000000000025847116641610512 Scatter Plot
Source ITGAL-ITGB2 Source IGF IGF Secreted Signaling -0.2870 0.00000000006121821597106356 Scatter Plot
Source ITGAL-ITGB2 Source NOTCH NOTCH Cell-Cell Contact -0.2847 0.00000000008802169205933805 Scatter Plot
Source ITGAL-ITGB2 Source LAMININ LAMININ ECM-Receptor -0.2834 0.00000000010906319597144975 Scatter Plot
Target ITGAL-ITGB2 Target CEACAM CEACAM Cell-Cell Contact -0.2815 0.00000000014611913760949363 Scatter Plot
Target ITGAL-ITGB2 Source CD52 CD52 Cell-Cell Contact -0.2795 0.00000000019905243220929418 Scatter Plot
Source ITGAL-ITGB2 Source RANKL RANKL Secreted Signaling -0.2776 0.0000000002684997866419613 Scatter Plot
Source ITGAL-ITGB2 Source ICAM ICAM Cell-Cell Contact -0.2735 0.000000000496452285841615 Scatter Plot
Source ITGAL-ITGB2 Source VEGF VEGF Secreted Signaling -0.2566 0.000000005808783381492479 Scatter Plot
Target ITGAL-ITGB2 Source COMPLEMENT COMPLEMENT Secreted Signaling -0.2549 0.000000007452956055990618 Scatter Plot
Target ITGAL-ITGB2 Source BAFF BAFF Secreted Signaling -0.2492 0.00000001618659996002638 Scatter Plot
Target ITGAL-ITGB2 Target ICAM ICAM Cell-Cell Contact -0.2491 0.000000016568111234938424 Scatter Plot
Target ITGAL-ITGB2 Target VCAM VCAM Cell-Cell Contact -0.2452 0.00000002786336803025945 Scatter Plot
Source ITGAL-ITGB2 Source CD46 CD46 Cell-Cell Contact -0.2358 0.0000000956267308145746 Scatter Plot
Target ITGAL-ITGB2 Source VISTA VISTA Cell-Cell Contact -0.2294 0.00000021539094824666557 Scatter Plot
Target ITGAL-ITGB2 Target CCL CCL Secreted Signaling -0.2098 0.000002229305712372669 Scatter Plot
Target ITGAL-ITGB2 Target IL1 IL1 Secreted Signaling -0.1984 0.000007858221910334738 Scatter Plot
Target ITGAL-ITGB2 Source SELL SELL Cell-Cell Contact -0.1920 0.000015377000416735503 Scatter Plot
Target ITGAL-ITGB2 Source NCAM NCAM Cell-Cell Contact -0.1915 0.00001614586458943108 Scatter Plot
Target ITGAL-ITGB2 Source ANNEXIN ANNEXIN Secreted Signaling -0.1884 0.000022418935712139737 Scatter Plot
Source ITGAL-ITGB2 Source CD45 CD45 Cell-Cell Contact -0.1811 0.00004642904615658449 Scatter Plot
Target ITGAL-ITGB2 Target GRN GRN Secreted Signaling -0.1748 0.00008542547979945631 Scatter Plot
Source ITGAL-ITGB2 Source CADM CADM Cell-Cell Contact -0.1742 0.00008981633605948725 Scatter Plot
Source ITGAL-ITGB2 Source LIGHT LIGHT Secreted Signaling -0.1704 0.0001286638712758 Scatter Plot
Target ITGAL-ITGB2 Source SEMA4 SEMA4 Cell-Cell Contact -0.1697 0.0001370814065091 Scatter Plot
Target ITGAL-ITGB2 Target SELE SELE Cell-Cell Contact -0.1625 0.0002623186795386 Scatter Plot
Target ITGAL-ITGB2 Target CLEC CLEC Cell-Cell Contact -0.1564 0.0004490877398082 Scatter Plot
Target ITGAL-ITGB2 Target CXCL CXCL Secreted Signaling -0.1338 0.0027095461223818 Scatter Plot
Target ITGAL-ITGB2 Target CD23 CD23 Cell-Cell Contact -0.1315 0.003227435288553 Scatter Plot
Target ITGAL-ITGB2 Target ANGPTL ANGPTL Secreted Signaling -0.1313 0.0032708455342514 Scatter Plot
Source ITGAL-ITGB2 Source APELIN APELIN Secreted Signaling -0.1286 0.0039706077090403 Scatter Plot
Source ITGAL-ITGB2 Source IL2 IL2 Secreted Signaling -0.1248 0.0052044571369278 Scatter Plot
Source ITGAL-ITGB2 Source GDF GDF Secreted Signaling -0.1236 0.0056586643620437 Scatter Plot
Target ITGAL-ITGB2 Target COLLAGEN COLLAGEN ECM-Receptor -0.1231 0.005831925294044 Scatter Plot
Target ITGAL-ITGB2 Source THBS THBS ECM-Receptor -0.1135 0.0110655003307306 Scatter Plot
Target ITGAL-ITGB2 Source PARs PARs Secreted Signaling -0.1087 0.0150051963013975 Scatter Plot
Target ITGAL-ITGB2 Source ANGPTL ANGPTL Secreted Signaling -0.1002 0.0251006969105791 Scatter Plot
Target ITGAL-ITGB2 Source TNF TNF Secreted Signaling -0.0979 0.028656338761828 Scatter Plot
Source ITGAL-ITGB2 Target GALECTIN GALECTIN Secreted Signaling 0.0991 0.0267046361634769 Scatter Plot
Source ITGAL-ITGB2 Target SELPLG SELPLG Cell-Cell Contact 0.1037 0.0203812722778902 Scatter Plot
Source ITGAL-ITGB2 Target CD86 CD86 Cell-Cell Contact 0.1052 0.0186214815411334 Scatter Plot
Source ITGAL-ITGB2 Target LAIR1 LAIR1 Cell-Cell Contact 0.1191 0.0076628934693252 Scatter Plot
Source ITGAL-ITGB2 Target BST2 BST2 Cell-Cell Contact 0.1191 0.0076628934693252 Scatter Plot
Source ITGAL-ITGB2 Target VEGF VEGF Secreted Signaling 0.1210 0.0067502260405985 Scatter Plot
Source ITGAL-ITGB2 Target GRN GRN Secreted Signaling 0.1282 0.0040984613485539 Scatter Plot
Source ITGAL-ITGB2 Source NKG2D NKG2D Cell-Cell Contact 0.1294 0.0037584679124882 Scatter Plot
Target ITGAL-ITGB2 Target LAMININ LAMININ ECM-Receptor 0.1592 0.0003505457393954 Scatter Plot
Target ITGAL-ITGB2 Target NRG NRG Secreted Signaling 0.1613 0.0002918498068283 Scatter Plot
Source ITGAL-ITGB2 Target SEMA3 SEMA3 Secreted Signaling 0.1678 0.0001631767294082 Scatter Plot
Source ITGAL-ITGB2 Source IL1 IL1 Secreted Signaling 0.1694 0.0001407667980476 Scatter Plot
Source ITGAL-ITGB2 Target SELE SELE Cell-Cell Contact 0.1728 0.0001029119574009 Scatter Plot
Source ITGAL-ITGB2 Target IL1 IL1 Secreted Signaling 0.1732 0.00009885881786213202 Scatter Plot
Target ITGAL-ITGB2 Target SELL SELL Cell-Cell Contact 0.1736 0.00009526915305306088 Scatter Plot
Source ITGAL-ITGB2 Target IL17 IL17 Secreted Signaling 0.1824 0.00004068819570298194 Scatter Plot
Source ITGAL-ITGB2 Source LAIR1 LAIR1 Cell-Cell Contact 0.1992 0.000007172711636531867 Scatter Plot
Source ITGAL-ITGB2 Source BAFF BAFF Secreted Signaling 0.2095 0.0000023044949377529147 Scatter Plot
Target ITGAL-ITGB2 Target BAFF BAFF Secreted Signaling 0.2307 0.00000018170722255249205 Scatter Plot
Source ITGAL-ITGB2 Source SPP1 SPP1 Secreted Signaling 0.2414 0.00000004618999097342793 Scatter Plot
Source ITGAL-ITGB2 Target COLLAGEN COLLAGEN ECM-Receptor 0.2420 0.00000004280394167869254 Scatter Plot
Source ITGAL-ITGB2 Source TGFb TGFb Secreted Signaling 0.2492 0.000000016177929228453096 Scatter Plot
Source ITGAL-ITGB2 Source APP APP Cell-Cell Contact 0.2544 0.000000007890076780754172 Scatter Plot
Source ITGAL-ITGB2 Source CCL CCL Secreted Signaling 0.2547 0.000000007591641651591426 Scatter Plot
Source ITGAL-ITGB2 Source SELPLG SELPLG Cell-Cell Contact 0.2766 0.0000000003106208308337945 Scatter Plot
Target ITGAL-ITGB2 Target SEMA4 SEMA4 Cell-Cell Contact 0.2971 0.00000000001188609457909464 Scatter Plot
Source ITGAL-ITGB2 Target VCAM VCAM Cell-Cell Contact 0.3095 0.0000000000014668830229205742 Scatter Plot
Target ITGAL-ITGB2 Target PARs PARs Secreted Signaling 0.3164 0.0000000000004335157469530654 Scatter Plot
Source ITGAL-ITGB2 Target ANNEXIN ANNEXIN Secreted Signaling 0.3294 0.000000000000040554951470126686 Scatter Plot
Source ITGAL-ITGB2 Source TNF TNF Secreted Signaling 0.3305 0.00000000000003263246604015743 Scatter Plot
Source ITGAL-ITGB2 Target IFN-II IFN-II Secreted Signaling 0.3321 0.000000000000024363933409890528 Scatter Plot
Source ITGAL-ITGB2 Target CSF CSF Secreted Signaling 0.3326 0.00000000000002215718401538383 Scatter Plot
Source ITGAL-ITGB2 Target CXCL CXCL Secreted Signaling 0.3499 0.0000000000000007510548826745652 Scatter Plot
Source ITGAL-ITGB2 Source ANNEXIN ANNEXIN Secreted Signaling 0.3515 0.0000000000000005456027325068853 Scatter Plot
Source ITGAL-ITGB2 Source CLEC CLEC Cell-Cell Contact 0.3711 0.000000000000000009005694894834898 Scatter Plot
Source ITGAL-ITGB2 Target CLEC CLEC Cell-Cell Contact 0.4042 0.0000000000000000000045016470932744 Scatter Plot
Source ITGAL-ITGB2 Target CEACAM CEACAM Cell-Cell Contact 0.4084 0.0000000000000000000015949261705774756 Scatter Plot
Source ITGAL-ITGB2 Target CCL CCL Secreted Signaling 0.4319 0.000000000000000000000003825510916420249 Scatter Plot
Source ITGAL-ITGB2 Target CD52 CD52 Cell-Cell Contact 0.4353 0.0000000000000000000000015345719115193744 Scatter Plot
Source ITGAL-ITGB2 Source SEMA4 SEMA4 Cell-Cell Contact 0.4614 0.0000000000000000000000000009837778749251443 Scatter Plot
Source ITGAL-ITGB2 Source COMPLEMENT COMPLEMENT Secreted Signaling 0.5492 0.00000000000000000000000000000000000000009533382533435587 Scatter Plot
Source ITGAL-ITGB2 Source CD52 CD52 Cell-Cell Contact 0.6335 0.0000000000000000000000000000000000000000000000000000000017422952271541645 Scatter Plot
Source ITGAL-ITGB2 Source MHC-I MHC-I Cell-Cell Contact -0.5630 0.0000000000000000000000000000000000000000003592209720912312 Scatter Plot
Source ITGAL-ITGB2 Target CD34 CD34 Cell-Cell Contact -0.5275 0.0000000000000000000000000000000000003639970529693141 Scatter Plot
Source ITGAL-ITGB2 Target ESAM ESAM Cell-Cell Contact -0.5248 0.0000000000000000000000000000000000009566489365366877 Scatter Plot
Source ITGAL-ITGB2 Source BST2 BST2 Cell-Cell Contact -0.4897 0.00000000000000000000000000000016112969612135112 Scatter Plot
Source ITGAL-ITGB2 Target WNT WNT Secreted Signaling -0.4838 0.0000000000000000000000000000010491068458472563 Scatter Plot
Source ITGAL-ITGB2 Source MHC-II MHC-II Cell-Cell Contact -0.4818 0.000000000000000000000000000001954559485135826 Scatter Plot
Source ITGAL-ITGB2 Source COLLAGEN COLLAGEN ECM-Receptor -0.4806 0.0000000000000000000000000000028925246792693963 Scatter Plot
Source ITGAL-ITGB2 Source GAS GAS Secreted Signaling -0.4680 0.00000000000000000000000000013713037651472814 Scatter Plot
Source ITGAL-ITGB2 Target FGF FGF Secreted Signaling -0.4680 0.00000000000000000000000000013810717605623892 Scatter Plot
Source ITGAL-ITGB2 Target ncWNT ncWNT Secreted Signaling -0.4675 0.0000000000000000000000000001627390558503092 Scatter Plot
Source ITGAL-ITGB2 Target KIT KIT Secreted Signaling -0.4634 0.0000000000000000000000000005401404415720292 Scatter Plot
Source ITGAL-ITGB2 Target CD39 CD39 Cell-Cell Contact -0.4439 0.0000000000000000000000001448921955378037 Scatter Plot
Source ITGAL-ITGB2 Target SLURP SLURP Secreted Signaling -0.4341 0.000000000000000000000002138800824053965 Scatter Plot
Source ITGAL-ITGB2 Target IGF IGF Secreted Signaling -0.4330 0.000000000000000000000002839775694072713 Scatter Plot
Source ITGAL-ITGB2 Target TENASCIN TENASCIN ECM-Receptor -0.4285 0.000000000000000000000009552132997178857 Scatter Plot
Source ITGAL-ITGB2 Target PARs PARs Secreted Signaling -0.4249 0.000000000000000000000023995420203398937 Scatter Plot
Source ITGAL-ITGB2 Source FLT3 FLT3 Secreted Signaling -0.4235 0.000000000000000000000035013349282992854 Scatter Plot
Source ITGAL-ITGB2 Source LCK LCK Cell-Cell Contact -0.4215 0.00000000000000000000005924369904631393 Scatter Plot
Source ITGAL-ITGB2 Target ANGPT ANGPT Secreted Signaling -0.4183 0.0000000000000000000001331181568339752 Scatter Plot
Source ITGAL-ITGB2 Target VWF VWF ECM-Receptor -0.3911 0.00000000000000000010054108797985057 Scatter Plot
Source ITGAL-ITGB2 Target CDH CDH Cell-Cell Contact -0.3864 0.00000000000000000029343514101468653 Scatter Plot
Source ITGAL-ITGB2 Source CDH CDH Cell-Cell Contact -0.3864 0.00000000000000000029343514101468653 Scatter Plot
Source ITGAL-ITGB2 Target MK MK Secreted Signaling -0.3852 0.0000000000000000003936820952158925 Scatter Plot
Source ITGAL-ITGB2 Source EPHB EPHB Cell-Cell Contact -0.3821 0.0000000000000000007872970282019454 Scatter Plot
Source ITGAL-ITGB2 Target APP APP Cell-Cell Contact -0.3816 0.0000000000000000008900524245667395 Scatter Plot
Source ITGAL-ITGB2 Target NPR2 NPR2 Secreted Signaling -0.3774 0.000000000000000002235874385156432 Scatter Plot
Source ITGAL-ITGB2 Target SEMA5 SEMA5 Cell-Cell Contact -0.3738 0.0000000000000000050197774435906554 Scatter Plot
Source ITGAL-ITGB2 Target SEMA4 SEMA4 Cell-Cell Contact -0.3656 0.000000000000000029143140141467134 Scatter Plot
Source ITGAL-ITGB2 Source IL7 IL7 Secreted Signaling -0.3650 0.00000000000000003351472312669069 Scatter Plot
Source ITGAL-ITGB2 Target BMP BMP Secreted Signaling -0.3515 0.0000000000000005471008523886402 Scatter Plot
Source ITGAL-ITGB2 Target DMP1 DMP1 ECM-Receptor -0.3510 0.0000000000000006018638799360034 Scatter Plot
Source ITGAL-ITGB2 Target VISFATIN VISFATIN Secreted Signaling -0.3510 0.0000000000000006076131898603387 Scatter Plot
Source ITGAL-ITGB2 Target PTN PTN Secreted Signaling -0.3494 0.0000000000000008417642525534917 Scatter Plot
Source ITGAL-ITGB2 Target VTN VTN ECM-Receptor -0.3388 0.000000000000006780884373929207 Scatter Plot
Source ITGAL-ITGB2 Target NRG NRG Secreted Signaling -0.3383 0.000000000000007489368714856453 Scatter Plot
Source ITGAL-ITGB2 Target BSP BSP ECM-Receptor -0.3371 0.00000000000000936499843180326 Scatter Plot
Source ITGAL-ITGB2 Target MIF MIF Secreted Signaling -0.3309 0.000000000000030594864772732026 Scatter Plot
Source ITGAL-ITGB2 Source MK MK Secreted Signaling -0.3303 0.000000000000034391299574208084 Scatter Plot
Source ITGAL-ITGB2 Target CD200 CD200 Cell-Cell Contact -0.3279 0.000000000000053882025642720126 Scatter Plot
Source ITGAL-ITGB2 Source CX3C CX3C Secreted Signaling -0.3251 0.00000000000009008340934989832 Scatter Plot
Source ITGAL-ITGB2 Target PERIOSTIN PERIOSTIN Secreted Signaling -0.3200 0.00000000000022692709091059187 Scatter Plot
Source ITGAL-ITGB2 Target SEMA6 SEMA6 Cell-Cell Contact -0.3188 0.00000000000028049293980661205 Scatter Plot
Source ITGAL-ITGB2 Target AGT AGT Secreted Signaling -0.3094 0.000000000001483428920294126 Scatter Plot
Source ITGAL-ITGB2 Source PROS PROS Secreted Signaling -0.3092 0.000000000001532422397337677 Scatter Plot
Source ITGAL-ITGB2 Target SPP1 SPP1 Secreted Signaling -0.3029 0.000000000004513301868871413 Scatter Plot
Source ITGAL-ITGB2 Target ANGPTL ANGPTL Secreted Signaling -0.3015 0.000000000005748936088232092 Scatter Plot
Source ITGAL-ITGB2 Target SEMA7 SEMA7 Cell-Cell Contact -0.3011 0.000000000006174588138736335 Scatter Plot
Source ITGAL-ITGB2 Target EPHB EPHB Cell-Cell Contact -0.2954 0.00000000001573811051920239 Scatter Plot
Source ITGAL-ITGB2 Source IGF IGF Secreted Signaling -0.2849 0.00000000008607865183785542 Scatter Plot
Source ITGAL-ITGB2 Target BAFF BAFF Secreted Signaling -0.2836 0.00000000010511197033304995 Scatter Plot
Source ITGAL-ITGB2 Target THBS THBS ECM-Receptor -0.2738 0.000000000474331558749994 Scatter Plot
Source ITGAL-ITGB2 Source ICAM ICAM Cell-Cell Contact -0.2703 0.0000000007994472643508232 Scatter Plot
Source ITGAL-ITGB2 Source IL2 IL2 Secreted Signaling -0.2598 0.0000000036942501073682124 Scatter Plot
Source ITGAL-ITGB2 Target TGFb TGFb Secreted Signaling -0.2566 0.000000005872287114635302 Scatter Plot
Target ITGAL-ITGB2 Target ICAM ICAM Cell-Cell Contact -0.2524 0.0000000104375214982999 Scatter Plot
Target ITGAL-ITGB2 Target ANNEXIN ANNEXIN Secreted Signaling -0.2498 0.000000015035128363961835 Scatter Plot
Source ITGAL-ITGB2 Target ADIPONECTIN ADIPONECTIN Secreted Signaling -0.2462 0.000000024212258741886504 Scatter Plot
Source ITGAL-ITGB2 Source CXCL CXCL Secreted Signaling -0.2444 0.00000003109440144605909 Scatter Plot
Source ITGAL-ITGB2 Target LAMININ LAMININ ECM-Receptor -0.2417 0.00000004455781191271833 Scatter Plot
Source ITGAL-ITGB2 Source CD86 CD86 Cell-Cell Contact -0.2398 0.00000005677010099607709 Scatter Plot
Source ITGAL-ITGB2 Target FN1 FN1 ECM-Receptor -0.2380 0.00000007173573700589017 Scatter Plot
Source ITGAL-ITGB2 Target ACTIVIN ACTIVIN Secreted Signaling -0.2308 0.00000017915396735362075 Scatter Plot
Source ITGAL-ITGB2 Source CSF CSF Secreted Signaling -0.2279 0.0000002574508595487125 Scatter Plot
Source ITGAL-ITGB2 Source CD1D2 CD1D2 Cell-Cell Contact -0.2246 0.0000003890271523118394 Scatter Plot
Source ITGAL-ITGB2 Source GP1BA GP1BA Cell-Cell Contact -0.2206 0.0000006327746216200947 Scatter Plot
Source ITGAL-ITGB2 Target CSPG4 CSPG4 Cell-Cell Contact -0.2192 0.0000007464300536144233 Scatter Plot
Source ITGAL-ITGB2 Source VCAM VCAM Cell-Cell Contact -0.2111 0.000001910895500051915 Scatter Plot
Source ITGAL-ITGB2 Target VEGF VEGF Secreted Signaling -0.2106 0.000002017520379340228 Scatter Plot
Source ITGAL-ITGB2 Source GALECTIN GALECTIN Secreted Signaling -0.2092 0.0000023684867567126915 Scatter Plot
Target ITGAL-ITGB2 Target COMPLEMENT COMPLEMENT Secreted Signaling -0.2072 0.0000029863417413021936 Scatter Plot
Source ITGAL-ITGB2 Source CCL CCL Secreted Signaling -0.2063 0.000003297720644466125 Scatter Plot
Target ITGAL-ITGB2 Target IL1 IL1 Secreted Signaling -0.1991 0.000007289342106632674 Scatter Plot
Source ITGAL-ITGB2 Source CD39 CD39 Cell-Cell Contact -0.1826 0.00004001171131115098 Scatter Plot
Source ITGAL-ITGB2 Target CD22 CD22 Cell-Cell Contact -0.1811 0.0000464290461565844 Scatter Plot
Source ITGAL-ITGB2 Source SEMA3 SEMA3 Secreted Signaling -0.1807 0.00004845923108476752 Scatter Plot
Source ITGAL-ITGB2 Target OSM OSM Secreted Signaling -0.1798 0.00005290222599821486 Scatter Plot
Source ITGAL-ITGB2 Source PTN PTN Secreted Signaling -0.1751 0.00008273015549360436 Scatter Plot
Source ITGAL-ITGB2 Target CADM CADM Cell-Cell Contact -0.1742 0.00008981633605948725 Scatter Plot
Source ITGAL-ITGB2 Source ANGPTL ANGPTL Secreted Signaling -0.1725 0.0001061012338848 Scatter Plot
Source ITGAL-ITGB2 Target EPHA EPHA Cell-Cell Contact -0.1720 0.0001106514767107 Scatter Plot
Source ITGAL-ITGB2 Source THY1 THY1 Cell-Cell Contact -0.1620 0.0002763029176086 Scatter Plot
Source ITGAL-ITGB2 Source PSAP PSAP Secreted Signaling -0.1509 0.000710918258475 Scatter Plot
Target ITGAL-ITGB2 Target THY1 THY1 Cell-Cell Contact -0.1401 0.0016881347233613 Scatter Plot
Target ITGAL-ITGB2 Target CD52 CD52 Cell-Cell Contact -0.1261 0.0047359494026778 Scatter Plot
Source ITGAL-ITGB2 Target GDF GDF Secreted Signaling -0.1248 0.0052077619319357 Scatter Plot
Source ITGAL-ITGB2 Target COLLAGEN COLLAGEN ECM-Receptor -0.1205 0.0069845080707658 Scatter Plot
Target ITGAL-ITGB2 Target IFN-II IFN-II Secreted Signaling -0.1198 0.0073260531688442 Scatter Plot
Source ITGAL-ITGB2 Target NCAM NCAM Cell-Cell Contact -0.1087 0.0150310873539136 Scatter Plot
Source ITGAL-ITGB2 Target NODAL NODAL Secreted Signaling -0.1075 0.0161889615573424 Scatter Plot
Source ITGAL-ITGB2 Source AGRN AGRN ECM-Receptor -0.1051 0.0187265376350105 Scatter Plot
Source ITGAL-ITGB2 Target NOTCH NOTCH Cell-Cell Contact -0.1046 0.0192579100646094 Scatter Plot
Source ITGAL-ITGB2 Target SEMA3 SEMA3 Secreted Signaling -0.1025 0.0218919571703064 Scatter Plot

Cells that are targets of ITGAL-ITGB2 from HSCs*

Cells that are source of ITGAL-ITGB2 to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.