Pathway: TGFb

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Secreted Signaling

Details on the TGFb pathway:

Specificity Index HSPC as target: 0.066
HSPC as source: 0.824

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the TGFb pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target TGFb Source THBS THBS ECM-Receptor 0.0986 0.0274480067063763 Scatter Plot
Target TGFb Source ncWNT ncWNT Secreted Signaling 0.1020 0.022481070713188 Scatter Plot
Target TGFb Source SEMA6 SEMA6 Cell-Cell Contact 0.1028 0.0215486996872204 Scatter Plot
Target TGFb Target TWEAK TWEAK Secreted Signaling 0.1063 0.0174663679163504 Scatter Plot
Target TGFb Source AGRN AGRN ECM-Receptor 0.1067 0.0170478708525722 Scatter Plot
Source TGFb Source PECAM1 PECAM1 Cell-Cell Contact 0.1068 0.016915745333733 Scatter Plot
Target TGFb Source IL6 IL6 Secreted Signaling 0.1070 0.01673061494334 Scatter Plot
Target TGFb Target SEMA3 SEMA3 Secreted Signaling 0.1174 0.0086100102544082 Scatter Plot
Target TGFb Source ICOS ICOS Cell-Cell Contact 0.1236 0.0056341090987837 Scatter Plot
Target TGFb Target AGT AGT Secreted Signaling 0.1264 0.0046554735268682 Scatter Plot
Target TGFb Source GP1BA GP1BA Cell-Cell Contact 0.1277 0.0042492861674585 Scatter Plot
Source TGFb Source VISFATIN VISFATIN Secreted Signaling 0.1303 0.0035201456560872 Scatter Plot
Target TGFb Target THY1 THY1 Cell-Cell Contact 0.1314 0.0032551571257122 Scatter Plot
Target TGFb Source GDF GDF Secreted Signaling 0.1408 0.0015930666222476 Scatter Plot
Target TGFb Target VEGF VEGF Secreted Signaling 0.1454 0.0011099711863802 Scatter Plot
Target TGFb Source PTN PTN Secreted Signaling 0.1456 0.0010975671878181 Scatter Plot
Target TGFb Target NOTCH NOTCH Cell-Cell Contact 0.1475 0.000937502347661 Scatter Plot
Target TGFb Target IL1 IL1 Secreted Signaling 0.1525 0.0006206512137901 Scatter Plot
Target TGFb Source OSM OSM Secreted Signaling 0.1653 0.0002043846564549 Scatter Plot
Target TGFb Source NT NT Secreted Signaling 0.1667 0.0001800558407205 Scatter Plot
Target TGFb Target PDGF PDGF Secreted Signaling 0.1861 0.00002815189427406498 Scatter Plot
Target TGFb Source FGF FGF Secreted Signaling 0.1864 0.00002742696608343473 Scatter Plot
Target TGFb Source WNT WNT Secreted Signaling 0.1928 0.000014126105464615976 Scatter Plot
Target TGFb Source APELIN APELIN Secreted Signaling 0.1983 0.000007948745067801407 Scatter Plot
Target TGFb Target GALECTIN GALECTIN Secreted Signaling 0.1997 0.000006819813204959118 Scatter Plot
Target TGFb Source CD46 CD46 Cell-Cell Contact 0.2102 0.000002113131521385962 Scatter Plot
Target TGFb Target CADM CADM Cell-Cell Contact 0.2156 0.0000011415342011887984 Scatter Plot
Target TGFb Source CADM CADM Cell-Cell Contact 0.2156 0.0000011415342011887984 Scatter Plot
Target TGFb Target SEMA7 SEMA7 Cell-Cell Contact 0.2248 0.000000378177943693638 Scatter Plot
Target TGFb Target PTN PTN Secreted Signaling 0.2306 0.00000018539067927288773 Scatter Plot
Target TGFb Source VEGF VEGF Secreted Signaling 0.2400 0.0000000556995440684993 Scatter Plot
Target TGFb Source CD34 CD34 Cell-Cell Contact 0.2420 0.000000042755932446744474 Scatter Plot
Target TGFb Source ANGPTL ANGPTL Secreted Signaling 0.2475 0.00000002054531656963509 Scatter Plot
Source TGFb Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2492 0.000000016177929228453096 Scatter Plot
Target TGFb Target ANGPTL ANGPTL Secreted Signaling 0.2505 0.00000001354478104297069 Scatter Plot
Target TGFb Source CCL CCL Secreted Signaling 0.2536 0.00000000892048474939855 Scatter Plot
Target TGFb Source NOTCH NOTCH Cell-Cell Contact 0.2563 0.0000000060996385289393445 Scatter Plot
Target TGFb Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2563 0.000000006067287263215091 Scatter Plot
Target TGFb Source SEMA3 SEMA3 Secreted Signaling 0.2602 0.0000000034909598659116604 Scatter Plot
Target TGFb Target COLLAGEN COLLAGEN ECM-Receptor 0.2640 0.0000000020452898625455117 Scatter Plot
Target TGFb Target EPHA EPHA Cell-Cell Contact 0.2641 0.0000000019880470413754806 Scatter Plot
Target TGFb Target SPP1 SPP1 Secreted Signaling 0.2722 0.0000000006085220037853642 Scatter Plot
Target TGFb Source CD39 CD39 Cell-Cell Contact 0.2726 0.0000000005739934348567526 Scatter Plot
Target TGFb Source RANKL RANKL Secreted Signaling 0.2740 0.0000000004641820169044739 Scatter Plot
Target TGFb Target RANKL RANKL Secreted Signaling 0.2792 0.00000000020896210989823888 Scatter Plot
Target TGFb Source PROS PROS Secreted Signaling 0.2793 0.00000000020430050131120363 Scatter Plot
Target TGFb Source CXCL CXCL Secreted Signaling 0.2815 0.00000000014683056129745074 Scatter Plot
Target TGFb Target FN1 FN1 ECM-Receptor 0.2823 0.0000000001299776715170543 Scatter Plot
Target TGFb Source IL2 IL2 Secreted Signaling 0.2826 0.00000000012303634740666279 Scatter Plot
Target TGFb Source CD1D2 CD1D2 Cell-Cell Contact 0.2875 0.00000000005651964286677162 Scatter Plot
Target TGFb Target CSPG4 CSPG4 Cell-Cell Contact 0.2971 0.000000000012013913709377144 Scatter Plot
Target TGFb Source FLT3 FLT3 Secreted Signaling 0.3018 0.0000000000054795528618260886 Scatter Plot
Target TGFb Source CSF CSF Secreted Signaling 0.3038 0.000000000003859145046951871 Scatter Plot
Target TGFb Target SEMA6 SEMA6 Cell-Cell Contact 0.3146 0.0000000000006015973988916514 Scatter Plot
Target TGFb Target SEMA5 SEMA5 Cell-Cell Contact 0.3146 0.0000000000005987984944101251 Scatter Plot
Target TGFb Source LIFR LIFR Secreted Signaling 0.3202 0.0000000000002202914408030317 Scatter Plot
Source TGFb Source CD34 CD34 Cell-Cell Contact 0.3248 0.00000000000009547429426876411 Scatter Plot
Target TGFb Target VWF VWF ECM-Receptor 0.3249 0.0000000000000933755832772949 Scatter Plot
Target TGFb Source THY1 THY1 Cell-Cell Contact 0.3256 0.00000000000008177379078471724 Scatter Plot
Target TGFb Source IL16 IL16 Secreted Signaling 0.3292 0.00000000000004199052649571106 Scatter Plot
Target TGFb Target VTN VTN ECM-Receptor 0.3308 0.000000000000031356574766251025 Scatter Plot
Target TGFb Source MK MK Secreted Signaling 0.3380 0.000000000000007929902884026527 Scatter Plot
Target TGFb Source IGF IGF Secreted Signaling 0.3426 0.000000000000003245848680581256 Scatter Plot
Target TGFb Source LIGHT LIGHT Secreted Signaling 0.3429 0.0000000000000030574627696904546 Scatter Plot
Target TGFb Target THBS THBS ECM-Receptor 0.3458 0.0000000000000017128607878168537 Scatter Plot
Target TGFb Source PDGF PDGF Secreted Signaling 0.3478 0.0000000000000011588512602844102 Scatter Plot
Target TGFb Source VCAM VCAM Cell-Cell Contact 0.3597 0.00000000000000010232955012862021 Scatter Plot
Target TGFb Target NRG NRG Secreted Signaling 0.3631 0.000000000000000049592733780280613 Scatter Plot
Target TGFb Source ICAM ICAM Cell-Cell Contact 0.3661 0.000000000000000026140150227132938 Scatter Plot
Source TGFb Source ANGPTL ANGPTL Secreted Signaling 0.3680 0.00000000000000001734293092778236 Scatter Plot
Target TGFb Target NPR2 NPR2 Secreted Signaling 0.3682 0.000000000000000016681359492122098 Scatter Plot
Target TGFb Target BSP BSP ECM-Receptor 0.3723 0.00000000000000000694768498435803 Scatter Plot
Target TGFb Target LAMININ LAMININ ECM-Receptor 0.3728 0.000000000000000006222712597427162 Scatter Plot
Target TGFb Target DMP1 DMP1 ECM-Receptor 0.3752 0.00000000000000000364577699563496 Scatter Plot
Target TGFb Target IGF IGF Secreted Signaling 0.3773 0.000000000000000002316043268996268 Scatter Plot
Source TGFb Source FGF FGF Secreted Signaling 0.3779 0.000000000000000002020772326518892 Scatter Plot
Target TGFb Source EPHB EPHB Cell-Cell Contact 0.3780 0.0000000000000000019839507811682258 Scatter Plot
Target TGFb Source CD45 CD45 Cell-Cell Contact 0.3817 0.0000000000000000008663966664533873 Scatter Plot
Target TGFb Source LAMININ LAMININ ECM-Receptor 0.3877 0.0000000000000000002207939904673396 Scatter Plot
Target TGFb Source CD86 CD86 Cell-Cell Contact 0.3883 0.0000000000000000001896706552056048 Scatter Plot
Target TGFb Source BST2 BST2 Cell-Cell Contact 0.4056 0.000000000000000000003156661179988994 Scatter Plot
Target TGFb Source PSAP PSAP Secreted Signaling 0.4058 0.000000000000000000003007853272478658 Scatter Plot
Target TGFb Source CX3C CX3C Secreted Signaling 0.4099 0.0000000000000000000010888585689101057 Scatter Plot
Target TGFb Source SEMA7 SEMA7 Cell-Cell Contact 0.4103 0.0000000000000000000009969736273268589 Scatter Plot
Target TGFb Source BMP BMP Secreted Signaling 0.4109 0.0000000000000000000008640653869557542 Scatter Plot
Target TGFb Target TENASCIN TENASCIN ECM-Receptor 0.4127 0.0000000000000000000005407465506925626 Scatter Plot
Target TGFb Target CDH CDH Cell-Cell Contact 0.4148 0.00000000000000000000032549974644649145 Scatter Plot
Target TGFb Source CDH CDH Cell-Cell Contact 0.4148 0.00000000000000000000032549974644649145 Scatter Plot
Target TGFb Source LCK LCK Cell-Cell Contact 0.4161 0.0000000000000000000002329311103516617 Scatter Plot
Target TGFb Source TWEAK TWEAK Secreted Signaling 0.4170 0.00000000000000000000018302144682253704 Scatter Plot
Target TGFb Source IL7 IL7 Secreted Signaling 0.4173 0.00000000000000000000017130207517672577 Scatter Plot
Target TGFb Target ESAM ESAM Cell-Cell Contact 0.4261 0.000000000000000000000017617832258532026 Scatter Plot
Target TGFb Source ESAM ESAM Cell-Cell Contact 0.4261 0.000000000000000000000017617832258532026 Scatter Plot
Target TGFb Target EPHB EPHB Cell-Cell Contact 0.4268 0.00000000000000000000001495757732735399 Scatter Plot
Target TGFb Target SLURP SLURP Secreted Signaling 0.4269 0.000000000000000000000014570062658549238 Scatter Plot
Target TGFb Source JAM JAM Cell-Cell Contact 0.4726 0.000000000000000000000000000034793653715640565 Scatter Plot
Target TGFb Target ncWNT ncWNT Secreted Signaling 0.4838 0.0000000000000000000000000000010681911579431327 Scatter Plot
Target TGFb Source GAS GAS Secreted Signaling 0.4870 0.00000000000000000000000000000037547963743309976 Scatter Plot
Target TGFb Source COLLAGEN COLLAGEN ECM-Receptor 0.4970 0.00000000000000000000000000000001491835690893732 Scatter Plot
Target TGFb Target CD39 CD39 Cell-Cell Contact 0.4978 0.000000000000000000000000000000011168315526441172 Scatter Plot
Target TGFb Target APP APP Cell-Cell Contact 0.5018 0.0000000000000000000000000000000029657662893922925 Scatter Plot
Target TGFb Target WNT WNT Secreted Signaling 0.5240 0.0000000000000000000000000000000000012615009328930462 Scatter Plot
Target TGFb Source MHC-I MHC-I Cell-Cell Contact 0.5425 0.0000000000000000000000000000000000000012751288690210189 Scatter Plot
Target TGFb Source ANGPT ANGPT Secreted Signaling 0.5449 0.00000000000000000000000000000000000000050580399863448645 Scatter Plot
Target TGFb Source MHC-II MHC-II Cell-Cell Contact 0.5905 0.00000000000000000000000000000000000000000000000246039007012384 Scatter Plot
Source TGFb Source CDH CDH Cell-Cell Contact -0.3920 0.0000000000000000000810449987788448 Scatter Plot
Target TGFb Source SEMA4 SEMA4 Cell-Cell Contact -0.3427 0.000000000000003133435097443461 Scatter Plot
Source TGFb Source PDGF PDGF Secreted Signaling -0.3252 0.00000000000008869132757050583 Scatter Plot
Source TGFb Source TWEAK TWEAK Secreted Signaling -0.3108 0.0000000000011630414179441365 Scatter Plot
Target TGFb Source COMPLEMENT COMPLEMENT Secreted Signaling -0.3053 0.000000000003000321873900782 Scatter Plot
Target TGFb Source VISTA VISTA Cell-Cell Contact -0.2854 0.00000000007940750405502817 Scatter Plot
Target TGFb Source PARs PARs Secreted Signaling -0.2618 0.000000002791593350772544 Scatter Plot
Target TGFb Source CD52 CD52 Cell-Cell Contact -0.2615 0.0000000029292553956956814 Scatter Plot
Source TGFb Source ANGPT ANGPT Secreted Signaling -0.2578 0.000000004910420998524329 Scatter Plot
Target TGFb Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.2566 0.000000005872287114635302 Scatter Plot
Source TGFb Source VEGF VEGF Secreted Signaling -0.2389 0.00000006388276373925738 Scatter Plot
Target TGFb Source MIF MIF Secreted Signaling -0.2251 0.0000003668000852599392 Scatter Plot
Source TGFb Source PROS PROS Secreted Signaling -0.2122 0.0000016913917620074236 Scatter Plot
Target TGFb Target CEACAM CEACAM Cell-Cell Contact -0.2108 0.000001983596445894082 Scatter Plot
Target TGFb Source SELL SELL Cell-Cell Contact -0.2097 0.0000022350130624543315 Scatter Plot
Source TGFb Source ncWNT ncWNT Secreted Signaling -0.1947 0.000011547599600565216 Scatter Plot
Source TGFb Source SEMA3 SEMA3 Secreted Signaling -0.1884 0.0000222927689450346 Scatter Plot
Target TGFb Source NCAM NCAM Cell-Cell Contact -0.1776 0.00006495363272127293 Scatter Plot
Target TGFb Source SPP1 SPP1 Secreted Signaling -0.1633 0.0002461918425102 Scatter Plot
Target TGFb Source ANGPTL ANGPTL Secreted Signaling -0.1601 0.0003248676932613 Scatter Plot
Target TGFb Source CLEC CLEC Cell-Cell Contact -0.1562 0.0004552419560576 Scatter Plot
Target TGFb Target CXCL CXCL Secreted Signaling -0.1540 0.0005487577258946 Scatter Plot
Target TGFb Source VISFATIN VISFATIN Secreted Signaling -0.1489 0.000837194463307 Scatter Plot
Target TGFb Source APP APP Cell-Cell Contact -0.1423 0.0014175489390426 Scatter Plot
Target TGFb Source NKG2D NKG2D Cell-Cell Contact -0.1156 0.0096787782168262 Scatter Plot
Target TGFb Target IL17 IL17 Secreted Signaling -0.1143 0.0105111404311092 Scatter Plot
Target TGFb Target GRN GRN Secreted Signaling -0.1099 0.0139494654564507 Scatter Plot
Target TGFb Source IL1 IL1 Secreted Signaling -0.1024 0.0220089057390147 Scatter Plot
Source TGFb Source THBS THBS ECM-Receptor -0.1002 0.0251089172729944 Scatter Plot
Target TGFb Source CCL CCL Secreted Signaling -0.0992 0.0265999521184168 Scatter Plot
Target TGFb Target TWEAK TWEAK Secreted Signaling 0.1041 0.0199000164028045 Scatter Plot
Source TGFb Target PECAM1 PECAM1 Cell-Cell Contact 0.1068 0.0169157453337329 Scatter Plot
Source TGFb Target FN1 FN1 ECM-Receptor 0.1095 0.0142997897249559 Scatter Plot
Source TGFb Target TWEAK TWEAK Secreted Signaling 0.1112 0.0128102354064775 Scatter Plot
Source TGFb Target ENHO ENHO Secreted Signaling 0.1160 0.0094202316433402 Scatter Plot
Source TGFb Target THBS THBS ECM-Receptor 0.1303 0.0035058629587736 Scatter Plot
Target TGFb Target NCAM NCAM Cell-Cell Contact 0.1320 0.0031151342648821 Scatter Plot
Target TGFb Target THY1 THY1 Cell-Cell Contact 0.1335 0.0027755653620314 Scatter Plot
Source TGFb Target CXCL CXCL Secreted Signaling 0.1433 0.0013127776011211 Scatter Plot
Source TGFb Target MK MK Secreted Signaling 0.1478 0.0009174252224032 Scatter Plot
Target TGFb Target CD23 CD23 Cell-Cell Contact 0.1521 0.0006414768252547 Scatter Plot
Source TGFb Source ICAM ICAM Cell-Cell Contact 0.1538 0.000559831617583 Scatter Plot
Target TGFb Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1593 0.0003486115505081 Scatter Plot
Source TGFb Target ICAM ICAM Cell-Cell Contact 0.1646 0.0002190316817484 Scatter Plot
Target TGFb Target OSM OSM Secreted Signaling 0.1722 0.00010928830723 Scatter Plot
Source TGFb Source PARs PARs Secreted Signaling 0.1761 0.00007531357626503316 Scatter Plot
Source TGFb Target CCL CCL Secreted Signaling 0.1775 0.00006587237074828404 Scatter Plot
Source TGFb Source CLEC CLEC Cell-Cell Contact 0.1804 0.00004985240496271088 Scatter Plot
Source TGFb Target IL17 IL17 Secreted Signaling 0.1823 0.00004130995475825299 Scatter Plot
Source TGFb Source CCL CCL Secreted Signaling 0.1893 0.00002039137239515879 Scatter Plot
Source TGFb Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1960 0.000010125142724931736 Scatter Plot
Source TGFb Source SELL SELL Cell-Cell Contact 0.2043 0.000004103757406004541 Scatter Plot
Source TGFb Target PDGF PDGF Secreted Signaling 0.2303 0.0000001927889756627852 Scatter Plot
Source TGFb Source CD52 CD52 Cell-Cell Contact 0.2319 0.0000001577700754542662 Scatter Plot
Target TGFb Target SELL SELL Cell-Cell Contact 0.2372 0.00000007940214933349599 Scatter Plot
Target TGFb Target VISFATIN VISFATIN Secreted Signaling 0.2537 0.000000008706074992467737 Scatter Plot
Target TGFb Target MK MK Secreted Signaling 0.2559 0.000000006471915784665952 Scatter Plot
Target TGFb Target IL6 IL6 Secreted Signaling 0.2608 0.000000003237674530544758 Scatter Plot
Source TGFb Target CSF CSF Secreted Signaling 0.2656 0.000000001602634754617779 Scatter Plot
Target TGFb Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.2861 0.00000000007065824634660412 Scatter Plot
Source TGFb Source IL1 IL1 Secreted Signaling 0.3150 0.000000000000553108984361281 Scatter Plot
Source TGFb Target SELL SELL Cell-Cell Contact 0.3247 0.00000000000009716381427871013 Scatter Plot
Target TGFb Target ANGPT ANGPT Secreted Signaling 0.3491 0.000000000000000893740213295321 Scatter Plot
Target TGFb Target THBS THBS ECM-Receptor 0.3514 0.0000000000000005531132564959076 Scatter Plot
Target TGFb Target PERIOSTIN PERIOSTIN Secreted Signaling 0.3670 0.00000000000000002166236614855204 Scatter Plot
Source TGFb Source SELPLG SELPLG Cell-Cell Contact 0.3676 0.000000000000000019149148567668705 Scatter Plot
Target TGFb Target PARs PARs Secreted Signaling 0.3677 0.000000000000000018524461808782804 Scatter Plot
Target TGFb Target CD22 CD22 Cell-Cell Contact 0.3817 0.0000000000000000008663966664533873 Scatter Plot
Target TGFb Target SEMA4 SEMA4 Cell-Cell Contact 0.3893 0.00000000000000000015401235409945444 Scatter Plot
Source TGFb Source SEMA4 SEMA4 Cell-Cell Contact 0.3943 0.000000000000000000047945533426985505 Scatter Plot
Target TGFb Target TENASCIN TENASCIN ECM-Receptor 0.4070 0.000000000000000000002253427299473028 Scatter Plot
Source TGFb Source GALECTIN GALECTIN Secreted Signaling 0.4100 0.0000000000000000000010791141742600192 Scatter Plot
Target TGFb Target JAM JAM Cell-Cell Contact 0.4162 0.00000000000000000000022864015244277593 Scatter Plot
Target TGFb Target FGF FGF Secreted Signaling 0.4311 0.00000000000000000000000468714737440628 Scatter Plot
Target TGFb Target BAFF BAFF Secreted Signaling 0.4322 0.0000000000000000000000035413084815902194 Scatter Plot
Target TGFb Target CD34 CD34 Cell-Cell Contact 0.4339 0.00000000000000000000000223723645143231 Scatter Plot
Target TGFb Target KIT KIT Secreted Signaling 0.4688 0.00000000000000000000000000010839526246719762 Scatter Plot
Target TGFb Target CD200 CD200 Cell-Cell Contact 0.4718 0.000000000000000000000000000044054762344744254 Scatter Plot
Source TGFb Source MIF MIF Secreted Signaling 0.5549 0.000000000000000000000000000000000000000009737960446052358 Scatter Plot
Target TGFb Target MIF MIF Secreted Signaling 0.5597 0.0000000000000000000000000000000000000000014027125287291749 Scatter Plot
Source TGFb Target NCAM NCAM Cell-Cell Contact -0.5555 0.000000000000000000000000000000000000000007599152872852433 Scatter Plot
Source TGFb Target JAM JAM Cell-Cell Contact -0.5264 0.0000000000000000000000000000000000005380382997922188 Scatter Plot
Source TGFb Source GAS GAS Secreted Signaling -0.4521 0.00000000000000000000000001465660065146035 Scatter Plot
Source TGFb Target CD200 CD200 Cell-Cell Contact -0.4379 0.0000000000000000000000007704505911294234 Scatter Plot
Source TGFb Target APP APP Cell-Cell Contact -0.4254 0.00000000000000000000002126435176777175 Scatter Plot
Source TGFb Source JAM JAM Cell-Cell Contact -0.4248 0.00000000000000000000002505763209781187 Scatter Plot
Source TGFb Target MIF MIF Secreted Signaling -0.4233 0.00000000000000000000003640811729035693 Scatter Plot
Source TGFb Target CD23 CD23 Cell-Cell Contact -0.4166 0.00000000000000000000020639762060304336 Scatter Plot
Source TGFb Source IL16 IL16 Secreted Signaling -0.4059 0.0000000000000000000029268627585527037 Scatter Plot
Source TGFb Target CDH CDH Cell-Cell Contact -0.3920 0.0000000000000000000810449987788448 Scatter Plot
Source TGFb Source SEMA7 SEMA7 Cell-Cell Contact -0.3891 0.00000000000000000015986438976951792 Scatter Plot
Source TGFb Target THY1 THY1 Cell-Cell Contact -0.3874 0.0000000000000000002341719558302412 Scatter Plot
Source TGFb Target SLURP SLURP Secreted Signaling -0.3802 0.0000000000000000012068889694408413 Scatter Plot
Source TGFb Source CD45 CD45 Cell-Cell Contact -0.3766 0.0000000000000000026818619107267372 Scatter Plot
Source TGFb Target CD22 CD22 Cell-Cell Contact -0.3766 0.0000000000000000026818619107267372 Scatter Plot
Source TGFb Source BMP BMP Secreted Signaling -0.3669 0.000000000000000021991028506782178 Scatter Plot
Source TGFb Target ADIPONECTIN ADIPONECTIN Secreted Signaling -0.3638 0.00000000000000004273940598017442 Scatter Plot
Source TGFb Source MK MK Secreted Signaling -0.3638 0.00000000000000004299738213433897 Scatter Plot
Source TGFb Source MHC-I MHC-I Cell-Cell Contact -0.3599 0.00000000000000009761125314193399 Scatter Plot
Source TGFb Target ncWNT ncWNT Secreted Signaling -0.3552 0.0000000000000002579727113287953 Scatter Plot
Source TGFb Target FGF FGF Secreted Signaling -0.3551 0.0000000000000002611682429790959 Scatter Plot
Source TGFb Target WNT WNT Secreted Signaling -0.3512 0.0000000000000005834491768009327 Scatter Plot
Source TGFb Source CX3C CX3C Secreted Signaling -0.3481 0.000000000000001079092641417135 Scatter Plot
Source TGFb Source COLLAGEN COLLAGEN ECM-Receptor -0.3477 0.0000000000000011671405399262525 Scatter Plot
Source TGFb Source NOTCH NOTCH Cell-Cell Contact -0.3338 0.000000000000017623404743097277 Scatter Plot
Source TGFb Target IGF IGF Secreted Signaling -0.3254 0.0000000000000855379204731538 Scatter Plot
Source TGFb Source MHC-II MHC-II Cell-Cell Contact -0.3251 0.00000000000009037150252870532 Scatter Plot
Source TGFb Source IL7 IL7 Secreted Signaling -0.3234 0.00000000000012167285978592952 Scatter Plot
Source TGFb Source CD39 CD39 Cell-Cell Contact -0.3228 0.00000000000013764058629699264 Scatter Plot
Source TGFb Target ESAM ESAM Cell-Cell Contact -0.3216 0.0000000000001695706770566762 Scatter Plot
Source TGFb Source ESAM ESAM Cell-Cell Contact -0.3216 0.0000000000001695706770566762 Scatter Plot
Source TGFb Source LAMININ LAMININ ECM-Receptor -0.3077 0.000000000001983749299281371 Scatter Plot
Source TGFb Target NPR2 NPR2 Secreted Signaling -0.3035 0.000000000004091242714579735 Scatter Plot
Source TGFb Source IGF IGF Secreted Signaling -0.3016 0.000000000005636790204238413 Scatter Plot
Source TGFb Source IL2 IL2 Secreted Signaling -0.2899 0.00000000003853746965893834 Scatter Plot
Source TGFb Source PSAP PSAP Secreted Signaling -0.2895 0.000000000041114644459297075 Scatter Plot
Source TGFb Target DMP1 DMP1 ECM-Receptor -0.2812 0.00000000015307383789234102 Scatter Plot
Source TGFb Target BSP BSP ECM-Receptor -0.2800 0.00000000018433038586173948 Scatter Plot
Source TGFb Source BST2 BST2 Cell-Cell Contact -0.2785 0.00000000023153747742681454 Scatter Plot
Source TGFb Target COMPLEMENT COMPLEMENT Secreted Signaling -0.2745 0.0000000004259283612749629 Scatter Plot
Source TGFb Source FLT3 FLT3 Secreted Signaling -0.2712 0.0000000007008069249006036 Scatter Plot
Source TGFb Source BAFF BAFF Secreted Signaling -0.2690 0.0000000009721003578291786 Scatter Plot
Source TGFb Target PERIOSTIN PERIOSTIN Secreted Signaling -0.2679 0.0000000011433165670098043 Scatter Plot
Source TGFb Target ANGPTL ANGPTL Secreted Signaling -0.2663 0.0000000014624676709324327 Scatter Plot
Source TGFb Source CSF CSF Secreted Signaling -0.2649 0.0000000017902118141869874 Scatter Plot
Source TGFb Target GALECTIN GALECTIN Secreted Signaling -0.2624 0.0000000025740860167410132 Scatter Plot
Source TGFb Target BMP BMP Secreted Signaling -0.2595 0.0000000038869696200485954 Scatter Plot
Target TGFb Target CD52 CD52 Cell-Cell Contact -0.2581 0.000000004710180632794893 Scatter Plot
Source TGFb Target NRG NRG Secreted Signaling -0.2576 0.00000000503779664215663 Scatter Plot
Source TGFb Source CD86 CD86 Cell-Cell Contact -0.2576 0.0000000050585577393293276 Scatter Plot
Source TGFb Source RANKL RANKL Secreted Signaling -0.2460 0.000000025130850095218157 Scatter Plot
Source TGFb Source ANNEXIN ANNEXIN Secreted Signaling -0.2427 0.000000038725085472522116 Scatter Plot
Source TGFb Target CD39 CD39 Cell-Cell Contact -0.2407 0.00000005059548350028129 Scatter Plot
Target TGFb Target CSF CSF Secreted Signaling -0.2341 0.00000011860202885492865 Scatter Plot
Source TGFb Target AGT AGT Secreted Signaling -0.2337 0.00000012535811806951476 Scatter Plot
Source TGFb Source NT NT Secreted Signaling -0.2330 0.00000013586470870191366 Scatter Plot
Source TGFb Target ANNEXIN ANNEXIN Secreted Signaling -0.2325 0.0000001459932523754991 Scatter Plot
Source TGFb Target EPHB EPHB Cell-Cell Contact -0.2319 0.0000001578690689816667 Scatter Plot
Source TGFb Target IL1 IL1 Secreted Signaling -0.2318 0.00000015943782818834337 Scatter Plot
Source TGFb Target BAFF BAFF Secreted Signaling -0.2289 0.00000022914518374363445 Scatter Plot
Source TGFb Target THBS THBS ECM-Receptor -0.2215 0.0000005667743504698685 Scatter Plot
Source TGFb Target CD34 CD34 Cell-Cell Contact -0.2208 0.0000006140610335399174 Scatter Plot
Source TGFb Source GRN GRN Secreted Signaling -0.2163 0.000001044068786627427 Scatter Plot
Target TGFb Target VCAM VCAM Cell-Cell Contact -0.2145 0.0000012957895102441437 Scatter Plot
Source TGFb Source NCAM NCAM Cell-Cell Contact -0.2102 0.000002108043455640226 Scatter Plot
Target TGFb Target ICAM ICAM Cell-Cell Contact -0.2068 0.000003101179186580607 Scatter Plot
Source TGFb Target SEMA6 SEMA6 Cell-Cell Contact -0.2060 0.000003412618786053673 Scatter Plot
Source TGFb Target NODAL NODAL Secreted Signaling -0.2059 0.0000034340497995083955 Scatter Plot
Source TGFb Source CD46 CD46 Cell-Cell Contact -0.2049 0.000003827488604450573 Scatter Plot
Source TGFb Source APP APP Cell-Cell Contact -0.2047 0.000003937239814656118 Scatter Plot
Source TGFb Target CADM CADM Cell-Cell Contact -0.2007 0.000006131448419651228 Scatter Plot
Source TGFb Source CADM CADM Cell-Cell Contact -0.2007 0.000006131448419651228 Scatter Plot
Source TGFb Target SEMA5 SEMA5 Cell-Cell Contact -0.1996 0.000006879831257715968 Scatter Plot
Source TGFb Source CXCL CXCL Secreted Signaling -0.1931 0.000013696350147417814 Scatter Plot
Source TGFb Source LIGHT LIGHT Secreted Signaling -0.1930 0.000013848576759333686 Scatter Plot
Target TGFb Target CCL CCL Secreted Signaling -0.1913 0.000016593419718765814 Scatter Plot
Source TGFb Target CSPG4 CSPG4 Cell-Cell Contact -0.1825 0.00004038229905056705 Scatter Plot
Source TGFb Target ANGPT ANGPT Secreted Signaling -0.1805 0.00004898842501677473 Scatter Plot
Source TGFb Target COLLAGEN COLLAGEN ECM-Receptor -0.1805 0.00004938032168693727 Scatter Plot
Source TGFb Target TENASCIN TENASCIN ECM-Receptor -0.1797 0.00005315214821345827 Scatter Plot
Source TGFb Source LCK LCK Cell-Cell Contact -0.1761 0.00007499637999797288 Scatter Plot
Target TGFb Target IFN-II IFN-II Secreted Signaling -0.1721 0.0001103336367003 Scatter Plot
Source TGFb Source EPHB EPHB Cell-Cell Contact -0.1701 0.0001318215997394 Scatter Plot
Source TGFb Target EPHA EPHA Cell-Cell Contact -0.1676 0.0001668668047946 Scatter Plot
Source TGFb Source ICAM ICAM Cell-Cell Contact -0.1645 0.0002202436373916 Scatter Plot
Source TGFb Source CD1D2 CD1D2 Cell-Cell Contact -0.1639 0.0002321461032862 Scatter Plot
Source TGFb Target ACTIVIN ACTIVIN Secreted Signaling -0.1600 0.0003283658279284 Scatter Plot
Source TGFb Source LIFR LIFR Secreted Signaling -0.1594 0.0003467173601545 Scatter Plot
Source TGFb Source CCL CCL Secreted Signaling -0.1590 0.0003586746637378 Scatter Plot
Source TGFb Target GDF GDF Secreted Signaling -0.1566 0.0004399896927478 Scatter Plot
Source TGFb Target RANKL RANKL Secreted Signaling -0.1562 0.0004539034562107 Scatter Plot
Source TGFb Source VISTA VISTA Cell-Cell Contact -0.1491 0.0008231355283808 Scatter Plot
Source TGFb Target VISFATIN VISFATIN Secreted Signaling -0.1462 0.0010427946741995 Scatter Plot
Source TGFb Target SELE SELE Cell-Cell Contact -0.1423 0.0014229430258704 Scatter Plot
Source TGFb Target VCAM VCAM Cell-Cell Contact -0.1371 0.0021163401448097 Scatter Plot
Source TGFb Target SEMA4 SEMA4 Cell-Cell Contact -0.1333 0.0028257236656585 Scatter Plot
Source TGFb Target OSM OSM Secreted Signaling -0.1310 0.0033330594971949 Scatter Plot
Source TGFb Target SEMA3 SEMA3 Secreted Signaling -0.1298 0.0036359991114443 Scatter Plot
Source TGFb Target NOTCH NOTCH Cell-Cell Contact -0.1298 0.0036400076182783 Scatter Plot
Source TGFb Target VEGF VEGF Secreted Signaling -0.1262 0.0047079631263965 Scatter Plot
Source TGFb Source ICOS ICOS Cell-Cell Contact -0.1233 0.0057616671137525 Scatter Plot
Target TGFb Target CLEC CLEC Cell-Cell Contact -0.1224 0.0061451172691373 Scatter Plot
Source TGFb Target KIT KIT Secreted Signaling -0.1167 0.008999514463353 Scatter Plot
Source TGFb Target IL6 IL6 Secreted Signaling -0.1086 0.015124296710073 Scatter Plot
Source TGFb Source LAIR1 LAIR1 Cell-Cell Contact -0.1020 0.0225276997340226 Scatter Plot
Source TGFb Source THBS THBS ECM-Receptor -0.1003 0.0248570786576615 Scatter Plot

Cells that are targets of TGFb from HSCs*

Cells that are source of TGFb to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.