Pathway: ENHO

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Secreted Signaling

Details on the ENHO pathway:

Specificity Index HSPC as target: 0.321
HSPC as source: 0.312

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the ENHO pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target ENHO Source FN1 FN1 ECM-Receptor 0.0977 0.0289207747387538 Scatter Plot
Target ENHO Source PTN PTN Secreted Signaling 0.1023 0.0221587880814489 Scatter Plot
Target ENHO Source TGFb TGFb Secreted Signaling 0.1160 0.0094202316433402 Scatter Plot
Target ENHO Source FGF FGF Secreted Signaling 0.1188 0.0078158086486704 Scatter Plot
Target ENHO Source THBS THBS ECM-Receptor 0.1209 0.0067936172863391 Scatter Plot
Target ENHO Source AGRN AGRN ECM-Receptor 0.1371 0.0021271965707617 Scatter Plot
Target ENHO Source GAS GAS Secreted Signaling -0.1111 0.0129217803675376 Scatter Plot
Target ENHO Source SEMA7 SEMA7 Cell-Cell Contact -0.1026 0.0217787198446492 Scatter Plot
Target ENHO Source IL16 IL16 Secreted Signaling -0.0986 0.0275525931367218 Scatter Plot
Target ENHO Target CSF CSF Secreted Signaling 0.1179 0.0083430015093323 Scatter Plot
Target ENHO Target VEGF VEGF Secreted Signaling 0.1272 0.0043773084739884 Scatter Plot
Target ENHO Target IGF IGF Secreted Signaling -0.0996 0.0259498226778529 Scatter Plot

Cells that are targets of ENHO from HSCs*

    No cell populations

Cells that are source of ENHO to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.