Pathway: CSF

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Secreted Signaling

Details on the CSF pathway:

Specificity Index HSPC as target: 0.517
HSPC as source: 0.211

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the CSF pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Source CSF Source APELIN APELIN Secreted Signaling 0.0967 0.0305390146738602 Scatter Plot
Target CSF Source PECAM1 PECAM1 Cell-Cell Contact 0.1013 0.0234599601065879 Scatter Plot
Target CSF Target PECAM1 PECAM1 Cell-Cell Contact 0.1013 0.0234599601065879 Scatter Plot
Source CSF Source THBS THBS ECM-Receptor 0.1129 0.011518521608285 Scatter Plot
Target CSF Target ENHO ENHO Secreted Signaling 0.1179 0.0083430015093323 Scatter Plot
Source CSF Source IL6 IL6 Secreted Signaling 0.1228 0.0059749489802403 Scatter Plot
Source CSF Source ncWNT ncWNT Secreted Signaling 0.1264 0.0046367095459384 Scatter Plot
Target CSF Target SELE SELE Cell-Cell Contact 0.1295 0.003719096886249 Scatter Plot
Source CSF Source THY1 THY1 Cell-Cell Contact 0.1361 0.002286025080849 Scatter Plot
Target CSF Source SEMA6 SEMA6 Cell-Cell Contact 0.1418 0.0014795291824703 Scatter Plot
Source CSF Source ANGPTL ANGPTL Secreted Signaling 0.1431 0.0013303194287015 Scatter Plot
Target CSF Source FN1 FN1 ECM-Receptor 0.1445 0.001196172163612 Scatter Plot
Target CSF Target COLLAGEN COLLAGEN ECM-Receptor 0.1466 0.0010098209354744 Scatter Plot
Source CSF Source CXCL CXCL Secreted Signaling 0.1564 0.0004474341249377 Scatter Plot
Source CSF Source GDF GDF Secreted Signaling 0.1678 0.00016390106223 Scatter Plot
Target CSF Target CEACAM CEACAM Cell-Cell Contact 0.1710 0.0001220458874047 Scatter Plot
Source CSF Source CCL CCL Secreted Signaling 0.1869 0.000026120733546657096 Scatter Plot
Target CSF Source ANNEXIN ANNEXIN Secreted Signaling 0.1893 0.0000203833311616499 Scatter Plot
Target CSF Source GRN GRN Secreted Signaling 0.1941 0.000012404753686911604 Scatter Plot
Target CSF Source ANGPTL ANGPTL Secreted Signaling 0.1954 0.000010732695050441657 Scatter Plot
Source CSF Source CD39 CD39 Cell-Cell Contact 0.1967 0.000009370634895333184 Scatter Plot
Target CSF Source CLEC CLEC Cell-Cell Contact 0.1972 0.000008896415219651057 Scatter Plot
Target CSF Source TNF TNF Secreted Signaling 0.2032 0.000004666919040484646 Scatter Plot
Source CSF Source PTN PTN Secreted Signaling 0.2046 0.000003956992349345001 Scatter Plot
Source CSF Source CADM CADM Cell-Cell Contact 0.2068 0.00000311093888753488 Scatter Plot
Source CSF Source CD46 CD46 Cell-Cell Contact 0.2192 0.000000747348592719362 Scatter Plot
Target CSF Source CD34 CD34 Cell-Cell Contact 0.2252 0.0000003596920523675929 Scatter Plot
Source CSF Source IL16 IL16 Secreted Signaling 0.2260 0.0000003270621235711592 Scatter Plot
Source CSF Source EPHB EPHB Cell-Cell Contact 0.2298 0.00000020459729342335323 Scatter Plot
Source CSF Source SEMA3 SEMA3 Secreted Signaling 0.2451 0.000000028152039592376027 Scatter Plot
Source CSF Source LIFR LIFR Secreted Signaling 0.2470 0.000000022018566256653932 Scatter Plot
Target CSF Source VISFATIN VISFATIN Secreted Signaling 0.2556 0.000000006762465145560802 Scatter Plot
Source CSF Source VEGF VEGF Secreted Signaling 0.2583 0.000000004585936078892359 Scatter Plot
Source CSF Source WNT WNT Secreted Signaling 0.2590 0.000000004169127541762728 Scatter Plot
Source CSF Source CD45 CD45 Cell-Cell Contact 0.2632 0.000000002295607872171169 Scatter Plot
Target CSF Source TGFb TGFb Secreted Signaling 0.2656 0.000000001602634754617779 Scatter Plot
Target CSF Source SPP1 SPP1 Secreted Signaling 0.2719 0.0000000006295431632400925 Scatter Plot
Target CSF Target ICAM ICAM Cell-Cell Contact 0.2814 0.00000000014921987768968182 Scatter Plot
Target CSF Target SEMA3 SEMA3 Secreted Signaling 0.2888 0.00000000004641302285766997 Scatter Plot
Source CSF Source LAMININ LAMININ ECM-Receptor 0.3079 0.0000000000019108561438399003 Scatter Plot
Target CSF Source SEMA4 SEMA4 Cell-Cell Contact 0.3123 0.0000000000008967616567874266 Scatter Plot
Target CSF Source APP APP Cell-Cell Contact 0.3179 0.0000000000003315694261342662 Scatter Plot
Target CSF Target CXCL CXCL Secreted Signaling 0.3186 0.0000000000002907829715792104 Scatter Plot
Source CSF Source PROS PROS Secreted Signaling 0.3241 0.00000000000010825075230903013 Scatter Plot
Source CSF Source IGF IGF Secreted Signaling 0.3291 0.000000000000043043545282094663 Scatter Plot
Source CSF Source PSAP PSAP Secreted Signaling 0.3297 0.000000000000037989730018007955 Scatter Plot
Target CSF Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.3326 0.00000000000002215718401538383 Scatter Plot
Source CSF Source LIGHT LIGHT Secreted Signaling 0.3387 0.0000000000000069263842651154375 Scatter Plot
Source CSF Source NT NT Secreted Signaling 0.3422 0.0000000000000035056712593513203 Scatter Plot
Target CSF Target IL17 IL17 Secreted Signaling 0.3431 0.000000000000002920333330952535 Scatter Plot
Source CSF Source MK MK Secreted Signaling 0.3552 0.0000000000000002593220258871393 Scatter Plot
Source CSF Source FLT3 FLT3 Secreted Signaling 0.3570 0.00000000000000017908724443759007 Scatter Plot
Target CSF Source SELPLG SELPLG Cell-Cell Contact 0.3632 0.000000000000000048251135033757707 Scatter Plot
Source CSF Source IL7 IL7 Secreted Signaling 0.3645 0.00000000000000003704888597112568 Scatter Plot
Source CSF Source PDGF PDGF Secreted Signaling 0.3749 0.000000000000000003915778457184995 Scatter Plot
Target CSF Source CCL CCL Secreted Signaling 0.3765 0.000000000000000002759196033140269 Scatter Plot
Source CSF Source RANKL RANKL Secreted Signaling 0.3808 0.0000000000000000010567873004479531 Scatter Plot
Source CSF Source CDH CDH Cell-Cell Contact 0.3835 0.0000000000000000005719944167366887 Scatter Plot
Target CSF Source COMPLEMENT COMPLEMENT Secreted Signaling 0.3841 0.0000000000000000005050076898608449 Scatter Plot
Source CSF Source COLLAGEN COLLAGEN ECM-Receptor 0.3854 0.00000000000000000037080202650046624 Scatter Plot
Target CSF Source CD52 CD52 Cell-Cell Contact 0.3951 0.00000000000000000003930366754164091 Scatter Plot
Target CSF Source VISTA VISTA Cell-Cell Contact 0.4007 0.000000000000000000010287569323978144 Scatter Plot
Source CSF Source NOTCH NOTCH Cell-Cell Contact 0.4045 0.000000000000000000004169425533176949 Scatter Plot
Source CSF Source ESAM ESAM Cell-Cell Contact 0.4135 0.0000000000000000000004519513831228316 Scatter Plot
Source CSF Source GAS GAS Secreted Signaling 0.4283 0.000000000000000000000009932902865458793 Scatter Plot
Source CSF Source BMP BMP Secreted Signaling 0.4297 0.000000000000000000000006799983025437695 Scatter Plot
Source CSF Source ANGPT ANGPT Secreted Signaling 0.4361 0.0000000000000000000000012330382822073904 Scatter Plot
Target CSF Source MIF MIF Secreted Signaling 0.4405 0.0000000000000000000000003770442942029993 Scatter Plot
Source CSF Source SEMA7 SEMA7 Cell-Cell Contact 0.4537 0.000000000000000000000000009101638466861488 Scatter Plot
Source CSF Source TWEAK TWEAK Secreted Signaling 0.4567 0.000000000000000000000000003896615281998689 Scatter Plot
Source CSF Source MHC-II MHC-II Cell-Cell Contact 0.4666 0.00000000000000000000000000021289724390541637 Scatter Plot
Target CSF Source PARs PARs Secreted Signaling 0.4861 0.000000000000000000000000000000511867732406103 Scatter Plot
Source CSF Source JAM JAM Cell-Cell Contact 0.4871 0.0000000000000000000000000000003675538403222608 Scatter Plot
Target CSF Source SELL SELL Cell-Cell Contact 0.5245 0.0000000000000000000000000000000000010731924423759834 Scatter Plot
Target CSF Target CCL CCL Secreted Signaling 0.5537 0.000000000000000000000000000000000000000016183370998542272 Scatter Plot
Target CSF Target IGF IGF Secreted Signaling -0.4344 0.00000000000000000000000197824834215316 Scatter Plot
Target CSF Source ANGPT ANGPT Secreted Signaling -0.4248 0.000000000000000000000025036631427725253 Scatter Plot
Target CSF Source MHC-I MHC-I Cell-Cell Contact -0.4195 0.00000000000000000000009900514214403096 Scatter Plot
Target CSF Target KIT KIT Secreted Signaling -0.4180 0.00000000000000000000014507484870927926 Scatter Plot
Target CSF Source COLLAGEN COLLAGEN ECM-Receptor -0.3562 0.00000000000000020747887609752726 Scatter Plot
Target CSF Source EPHB EPHB Cell-Cell Contact -0.3388 0.000000000000006803785615218609 Scatter Plot
Target CSF Target ADIPONECTIN ADIPONECTIN Secreted Signaling -0.3371 0.000000000000009403697570531424 Scatter Plot
Target CSF Source FLT3 FLT3 Secreted Signaling -0.3320 0.000000000000024727802954099176 Scatter Plot
Target CSF Target ESAM ESAM Cell-Cell Contact -0.3278 0.000000000000054376145372004744 Scatter Plot
Target CSF Source ESAM ESAM Cell-Cell Contact -0.3278 0.000000000000054376145372004744 Scatter Plot
Target CSF Source JAM JAM Cell-Cell Contact -0.3276 0.000000000000056652948024644055 Scatter Plot
Target CSF Source MHC-II MHC-II Cell-Cell Contact -0.3257 0.00000000000008016270717455371 Scatter Plot
Target CSF Source GAS GAS Secreted Signaling -0.3229 0.00000000000013468264658763405 Scatter Plot
Target CSF Source GALECTIN GALECTIN Secreted Signaling -0.3185 0.0000000000002959242624226507 Scatter Plot
Source CSF Source CD52 CD52 Cell-Cell Contact -0.3147 0.0000000000005828813694653524 Scatter Plot
Target CSF Source LCK LCK Cell-Cell Contact -0.3055 0.000000000002926001523369058 Scatter Plot
Target CSF Target WNT WNT Secreted Signaling -0.2952 0.000000000016489744539743024 Scatter Plot
Target CSF Target MK MK Secreted Signaling -0.2940 0.000000000019985474381512997 Scatter Plot
Target CSF Source LIFR LIFR Secreted Signaling -0.2907 0.000000000034057265305440307 Scatter Plot
Target CSF Target VWF VWF ECM-Receptor -0.2861 0.00000000007157511579934086 Scatter Plot
Target CSF Source TWEAK TWEAK Secreted Signaling -0.2741 0.0000000004537234307499397 Scatter Plot
Target CSF Target CD39 CD39 Cell-Cell Contact -0.2698 0.000000000871321241816343 Scatter Plot
Target CSF Source BMP BMP Secreted Signaling -0.2692 0.000000000941129726791264 Scatter Plot
Source CSF Source TGFb TGFb Secreted Signaling -0.2649 0.0000000017902118141869874 Scatter Plot
Target CSF Source FGF FGF Secreted Signaling -0.2565 0.000000005915352895654711 Scatter Plot
Target CSF Target CD200 CD200 Cell-Cell Contact -0.2523 0.000000010572051904331181 Scatter Plot
Target CSF Source SEMA7 SEMA7 Cell-Cell Contact -0.2522 0.000000010714530234376645 Scatter Plot
Target CSF Target SLURP SLURP Secreted Signaling -0.2476 0.000000020146473446423605 Scatter Plot
Target CSF Source VEGF VEGF Secreted Signaling -0.2434 0.000000035497884068681455 Scatter Plot
Target CSF Source VCAM VCAM Cell-Cell Contact -0.2398 0.00000005688875667762725 Scatter Plot
Target CSF Source IL7 IL7 Secreted Signaling -0.2373 0.00000007890977214979414 Scatter Plot
Target CSF Source GP1BA GP1BA Cell-Cell Contact -0.2343 0.00000011543128076261757 Scatter Plot
Target CSF Target TGFb TGFb Secreted Signaling -0.2341 0.00000011860202885492865 Scatter Plot
Target CSF Target CDH CDH Cell-Cell Contact -0.2333 0.0000001309454281813445 Scatter Plot
Target CSF Source CDH CDH Cell-Cell Contact -0.2333 0.0000001309454281813445 Scatter Plot
Source CSF Source COMPLEMENT COMPLEMENT Secreted Signaling -0.2328 0.0000001392346786494552 Scatter Plot
Target CSF Source CXCL CXCL Secreted Signaling -0.2326 0.00000014285734412965414 Scatter Plot
Target CSF Source CD45 CD45 Cell-Cell Contact -0.2320 0.0000001553112367378984 Scatter Plot
Source CSF Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.2279 0.0000002574508595487125 Scatter Plot
Target CSF Target CD34 CD34 Cell-Cell Contact -0.2236 0.0000004404580337863146 Scatter Plot
Target CSF Source IL2 IL2 Secreted Signaling -0.2125 0.0000016296749561103225 Scatter Plot
Target CSF Target LAMININ LAMININ ECM-Receptor -0.2125 0.0000016329740936189903 Scatter Plot
Target CSF Source LIGHT LIGHT Secreted Signaling -0.2075 0.00000286333041866961 Scatter Plot
Target CSF Target FN1 FN1 ECM-Receptor -0.2074 0.000002916637140171082 Scatter Plot
Target CSF Source PDGF PDGF Secreted Signaling -0.2027 0.000004884842242372535 Scatter Plot
Target CSF Source CD86 CD86 Cell-Cell Contact -0.2012 0.000005759805873994815 Scatter Plot
Target CSF Target CSPG4 CSPG4 Cell-Cell Contact -0.2004 0.0000063036423599235295 Scatter Plot
Source CSF Source ANGPTL ANGPTL Secreted Signaling -0.1987 0.000007567258178580667 Scatter Plot
Target CSF Source IGF IGF Secreted Signaling -0.1890 0.000021012911485481877 Scatter Plot
Target CSF Target EPHB EPHB Cell-Cell Contact -0.1881 0.000022905681749595157 Scatter Plot
Target CSF Target SEMA6 SEMA6 Cell-Cell Contact -0.1832 0.000037771319636107805 Scatter Plot
Target CSF Source MK MK Secreted Signaling -0.1802 0.00005067588807740723 Scatter Plot
Target CSF Source CX3C CX3C Secreted Signaling -0.1766 0.00007188963228522297 Scatter Plot
Target CSF Source THY1 THY1 Cell-Cell Contact -0.1745 0.00008800950294974064 Scatter Plot
Source CSF Source SEMA4 SEMA4 Cell-Cell Contact -0.1737 0.00009437328955671845 Scatter Plot
Target CSF Target ACTIVIN ACTIVIN Secreted Signaling -0.1631 0.0002501813515818 Scatter Plot
Target CSF Target BMP BMP Secreted Signaling -0.1620 0.0002750174013756 Scatter Plot
Source CSF Source PARs PARs Secreted Signaling -0.1612 0.0002945523073464 Scatter Plot
Target CSF Source CD1D2 CD1D2 Cell-Cell Contact -0.1595 0.0003414845000937 Scatter Plot
Source CSF Source SELL SELL Cell-Cell Contact -0.1572 0.0004171744614241 Scatter Plot
Target CSF Source NOTCH NOTCH Cell-Cell Contact -0.1541 0.0005434942318885 Scatter Plot
Target CSF Source CCL CCL Secreted Signaling -0.1512 0.0006923693764062 Scatter Plot
Source CSF Source CLEC CLEC Cell-Cell Contact -0.1497 0.0007839188834951 Scatter Plot
Target CSF Target IL1 IL1 Secreted Signaling -0.1487 0.0008547164123959 Scatter Plot
Target CSF Source RANKL RANKL Secreted Signaling -0.1450 0.0011455919460875 Scatter Plot
Target CSF Source CD39 CD39 Cell-Cell Contact -0.1420 0.0014564265034652 Scatter Plot
Source CSF Source MIF MIF Secreted Signaling -0.1398 0.0017247310083587 Scatter Plot
Target CSF Source IL16 IL16 Secreted Signaling -0.1381 0.0019732151946667 Scatter Plot
Target CSF Source GDF GDF Secreted Signaling -0.1356 0.0023714952241939 Scatter Plot
Source CSF Source SPP1 SPP1 Secreted Signaling -0.1338 0.002721063912342 Scatter Plot
Target CSF Source LAMININ LAMININ ECM-Receptor -0.1330 0.0028764779238268 Scatter Plot
Target CSF Target BSP BSP ECM-Receptor -0.1314 0.0032514889962971 Scatter Plot
Target CSF Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1297 0.0036823360595732 Scatter Plot
Target CSF Source PTN PTN Secreted Signaling -0.1144 0.0104343863939811 Scatter Plot
Target CSF Source ANGPTL ANGPTL Secreted Signaling -0.1138 0.010858336914227 Scatter Plot
Target CSF Source IL6 IL6 Secreted Signaling -0.1093 0.014448236138694 Scatter Plot
Target CSF Target COLLAGEN COLLAGEN ECM-Receptor -0.1082 0.0154663665999197 Scatter Plot
Target CSF Source CD46 CD46 Cell-Cell Contact -0.1068 0.0168758885693768 Scatter Plot
Source CSF Source NCAM NCAM Cell-Cell Contact -0.1056 0.018220905784144 Scatter Plot
Source CSF Source VISTA VISTA Cell-Cell Contact -0.1019 0.0226127360700288 Scatter Plot
Target CSF Target VEGF VEGF Secreted Signaling -0.1007 0.0243891198614697 Scatter Plot
Target CSF Target AGT AGT Secreted Signaling -0.0991 0.0267572917282641 Scatter Plot
Target CSF Target GRN GRN Secreted Signaling 0.0976 0.0291446385928428 Scatter Plot
Source CSF Target TWEAK TWEAK Secreted Signaling 0.1032 0.0209694505051451 Scatter Plot
Source CSF Target SPP1 SPP1 Secreted Signaling 0.1163 0.009263818468855 Scatter Plot
Source CSF Target GAS GAS Secreted Signaling 0.1166 0.009070504500141 Scatter Plot
Target CSF Target SEMA4 SEMA4 Cell-Cell Contact 0.1170 0.0088320186329887 Scatter Plot
Source CSF Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1318 0.003139910683075 Scatter Plot
Source CSF Source CD1D2 CD1D2 Cell-Cell Contact 0.1367 0.0021892727247459 Scatter Plot
Source CSF Target SELPLG SELPLG Cell-Cell Contact 0.1445 0.0011976888493364 Scatter Plot
Source CSF Target FN1 FN1 ECM-Receptor 0.1458 0.0010764258035165 Scatter Plot
Source CSF Source ICOS ICOS Cell-Cell Contact 0.1506 0.0007298251959699 Scatter Plot
Target CSF Target COLLAGEN COLLAGEN ECM-Receptor 0.1515 0.0006772742245454 Scatter Plot
Source CSF Target PTN PTN Secreted Signaling 0.1639 0.0002334322617373 Scatter Plot
Source CSF Target VEGF VEGF Secreted Signaling 0.1642 0.0002255629419173 Scatter Plot
Source CSF Target THY1 THY1 Cell-Cell Contact 0.1667 0.0001804852398839 Scatter Plot
Target CSF Target CEACAM CEACAM Cell-Cell Contact 0.1710 0.0001220458874047 Scatter Plot
Source CSF Target NODAL NODAL Secreted Signaling 0.1780 0.00006294584581780572 Scatter Plot
Source CSF Target SEMA3 SEMA3 Secreted Signaling 0.1780 0.00006278926346145969 Scatter Plot
Target CSF Target VEGF VEGF Secreted Signaling 0.1805 0.00004933838322585487 Scatter Plot
Source CSF Target OSM OSM Secreted Signaling 0.1812 0.00004614461244364093 Scatter Plot
Source CSF Target COLLAGEN COLLAGEN ECM-Receptor 0.1816 0.00004416260443436814 Scatter Plot
Source CSF Target SEMA5 SEMA5 Cell-Cell Contact 0.1829 0.00003871162904840766 Scatter Plot
Source CSF Target CD23 CD23 Cell-Cell Contact 0.1838 0.000035485106128885055 Scatter Plot
Source CSF Target SEMA6 SEMA6 Cell-Cell Contact 0.1875 0.000024355373879856792 Scatter Plot
Source CSF Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.1999 0.000006658739216820952 Scatter Plot
Source CSF Target GDF GDF Secreted Signaling 0.2005 0.000006245207645294321 Scatter Plot
Source CSF Target SEMA7 SEMA7 Cell-Cell Contact 0.2022 0.000005208993078549109 Scatter Plot
Source CSF Target CADM CADM Cell-Cell Contact 0.2068 0.00000311093888753488 Scatter Plot
Target CSF Target SELL SELL Cell-Cell Contact 0.2154 0.0000011600911630157831 Scatter Plot
Source CSF Target NCAM NCAM Cell-Cell Contact 0.2166 0.0000010080696161466231 Scatter Plot
Source CSF Target BAFF BAFF Secreted Signaling 0.2192 0.0000007410232142636467 Scatter Plot
Source CSF Target KIT KIT Secreted Signaling 0.2232 0.0000004573143574420567 Scatter Plot
Target CSF Target CD86 CD86 Cell-Cell Contact 0.2240 0.0000004193707704745852 Scatter Plot
Source CSF Source CCL CCL Secreted Signaling 0.2288 0.00000023025182455000442 Scatter Plot
Source CSF Target LAMININ LAMININ ECM-Receptor 0.2305 0.00000018690310588206705 Scatter Plot
Source CSF Target ANGPTL ANGPTL Secreted Signaling 0.2379 0.00000007331547490847263 Scatter Plot
Source CSF Source CX3C CX3C Secreted Signaling 0.2383 0.0000000695924158951423 Scatter Plot
Source CSF Target EPHA EPHA Cell-Cell Contact 0.2387 0.00000006578952554618928 Scatter Plot
Source CSF Target AGT AGT Secreted Signaling 0.2471 0.000000021595954367215063 Scatter Plot
Source CSF Source CXCL CXCL Secreted Signaling 0.2480 0.000000019033278968464863 Scatter Plot
Source CSF Target VISFATIN VISFATIN Secreted Signaling 0.2495 0.000000015689222931932823 Scatter Plot
Source CSF Target THBS THBS ECM-Receptor 0.2516 0.000000011633797105683988 Scatter Plot
Source CSF Source ICAM ICAM Cell-Cell Contact 0.2541 0.000000008289898553814431 Scatter Plot
Source CSF Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2580 0.000000004805921778638935 Scatter Plot
Source CSF Target CD22 CD22 Cell-Cell Contact 0.2632 0.000000002295607872171186 Scatter Plot
Source CSF Target PARs PARs Secreted Signaling 0.2667 0.000000001379904632447939 Scatter Plot
Source CSF Source LCK LCK Cell-Cell Contact 0.2690 0.0000000009794985868761494 Scatter Plot
Source CSF Target VWF VWF ECM-Receptor 0.2725 0.0000000005784737579114836 Scatter Plot
Source CSF Target VTN VTN ECM-Receptor 0.2743 0.00000000044063905069938157 Scatter Plot
Source CSF Target ANGPT ANGPT Secreted Signaling 0.2857 0.00000000007596733601040265 Scatter Plot
Target CSF Target CXCL CXCL Secreted Signaling 0.2900 0.000000000038363329953395947 Scatter Plot
Source CSF Target EPHB EPHB Cell-Cell Contact 0.2911 0.00000000003213332000286283 Scatter Plot
Source CSF Target CSPG4 CSPG4 Cell-Cell Contact 0.2974 0.000000000011347335703199018 Scatter Plot
Source CSF Source CD86 CD86 Cell-Cell Contact 0.2979 0.000000000010411549744324592 Scatter Plot
Source CSF Target TGFb TGFb Secreted Signaling 0.3038 0.000000000003859145046951871 Scatter Plot
Source CSF Source IL2 IL2 Secreted Signaling 0.3138 0.0000000000006889150441653009 Scatter Plot
Source CSF Target NRG NRG Secreted Signaling 0.3145 0.0000000000006087471009903202 Scatter Plot
Target CSF Target IL6 IL6 Secreted Signaling 0.3211 0.00000000000018516970701133785 Scatter Plot
Source CSF Target ACTIVIN ACTIVIN Secreted Signaling 0.3215 0.0000000000001741815194611503 Scatter Plot
Source CSF Target SEMA4 SEMA4 Cell-Cell Contact 0.3235 0.00000000000012093588282857293 Scatter Plot
Source CSF Target TENASCIN TENASCIN ECM-Receptor 0.3250 0.00000000000009198377065478044 Scatter Plot
Source CSF Target PERIOSTIN PERIOSTIN Secreted Signaling 0.3312 0.000000000000029110949977246835 Scatter Plot
Source CSF Target BSP BSP ECM-Receptor 0.3348 0.000000000000014529663777572712 Scatter Plot
Source CSF Target DMP1 DMP1 ECM-Receptor 0.3396 0.000000000000005764769338116859 Scatter Plot
Source CSF Source COLLAGEN COLLAGEN ECM-Receptor 0.3437 0.000000000000002580753510198854 Scatter Plot
Source CSF Target IGF IGF Secreted Signaling 0.3470 0.0000000000000013559096484171629 Scatter Plot
Source CSF Target NPR2 NPR2 Secreted Signaling 0.3487 0.0000000000000009610627783569948 Scatter Plot
Source CSF Target APP APP Cell-Cell Contact 0.3694 0.000000000000000013052047418763608 Scatter Plot
Target CSF Target CCL CCL Secreted Signaling 0.3722 0.000000000000000007068605171856684 Scatter Plot
Source CSF Target FGF FGF Secreted Signaling 0.3738 0.000000000000000004936246279842094 Scatter Plot
Target CSF Target CD52 CD52 Cell-Cell Contact 0.3779 0.000000000000000002003526983195526 Scatter Plot
Source CSF Target BMP BMP Secreted Signaling 0.3825 0.0000000000000000007145298485851544 Scatter Plot
Source CSF Target CDH CDH Cell-Cell Contact 0.3835 0.0000000000000000005719944167366887 Scatter Plot
Source CSF Target CD200 CD200 Cell-Cell Contact 0.3935 0.00000000000000000005796307512043496 Scatter Plot
Source CSF Target SLURP SLURP Secreted Signaling 0.3950 0.00000000000000000004052009274593082 Scatter Plot
Source CSF Target ESAM ESAM Cell-Cell Contact 0.4135 0.0000000000000000000004519513831228316 Scatter Plot
Source CSF Target ncWNT ncWNT Secreted Signaling 0.4156 0.0000000000000000000002616635026026818 Scatter Plot
Source CSF Target WNT WNT Secreted Signaling 0.4219 0.00000000000000000000005283383425278136 Scatter Plot
Source CSF Target CD39 CD39 Cell-Cell Contact 0.4312 0.000000000000000000000004628673193287194 Scatter Plot
Target CSF Target SELPLG SELPLG Cell-Cell Contact 0.4337 0.0000000000000000000000023458238430693643 Scatter Plot
Source CSF Source BST2 BST2 Cell-Cell Contact 0.4341 0.0000000000000000000000021488483770105916 Scatter Plot
Target CSF Target IFN-II IFN-II Secreted Signaling 0.4388 0.00000000000000000000000060159515578958845 Scatter Plot
Source CSF Source MHC-I MHC-I Cell-Cell Contact 0.4474 0.00000000000000000000000005555045593118165 Scatter Plot
Source CSF Target CD34 CD34 Cell-Cell Contact 0.4474 0.0000000000000000000000000547740414048638 Scatter Plot
Source CSF Target MIF MIF Secreted Signaling 0.4532 0.000000000000000000000000010640237775419768 Scatter Plot
Target CSF Target CLEC CLEC Cell-Cell Contact 0.4541 0.000000000000000000000000008204606495954182 Scatter Plot
Source CSF Target JAM JAM Cell-Cell Contact 0.4604 0.0000000000000000000000000013321041842595904 Scatter Plot
Target CSF Target PARs PARs Secreted Signaling -0.4221 0.00000000000000000000004985235613235003 Scatter Plot
Target CSF Target ncWNT ncWNT Secreted Signaling -0.3424 0.000000000000003368885440625307 Scatter Plot
Source CSF Source CD52 CD52 Cell-Cell Contact -0.3147 0.0000000000005828813694653524 Scatter Plot
Target CSF Target JAM JAM Cell-Cell Contact -0.3122 0.0000000000009092771321854012 Scatter Plot
Target CSF Target SEMA7 SEMA7 Cell-Cell Contact -0.3036 0.00000000000400284052674555 Scatter Plot
Target CSF Target TENASCIN TENASCIN ECM-Receptor -0.2967 0.000000000012757065822529816 Scatter Plot
Target CSF Target FGF FGF Secreted Signaling -0.2857 0.00000000007529042004746487 Scatter Plot
Target CSF Target ANGPT ANGPT Secreted Signaling -0.2825 0.00000000012518525517002653 Scatter Plot
Target CSF Target SEMA4 SEMA4 Cell-Cell Contact -0.2708 0.0000000007502558724169449 Scatter Plot
Target CSF Target CD39 CD39 Cell-Cell Contact -0.2698 0.000000000871321241816343 Scatter Plot
Target CSF Target CD200 CD200 Cell-Cell Contact -0.2522 0.00000001074251949630231 Scatter Plot
Target CSF Target CDH CDH Cell-Cell Contact -0.2333 0.0000001309454281813445 Scatter Plot
Source CSF Source COMPLEMENT COMPLEMENT Secreted Signaling -0.2328 0.0000001392346786494542 Scatter Plot
Target CSF Target CD22 CD22 Cell-Cell Contact -0.2320 0.0000001553112367378984 Scatter Plot
Target CSF Target THBS THBS ECM-Receptor -0.2291 0.00000022413129984106722 Scatter Plot
Target CSF Target SPP1 SPP1 Secreted Signaling -0.2237 0.0000004337144427046923 Scatter Plot
Target CSF Target CD34 CD34 Cell-Cell Contact -0.2236 0.0000004404580337863129 Scatter Plot
Target CSF Target SEMA5 SEMA5 Cell-Cell Contact -0.2222 0.0000005195209561852148 Scatter Plot
Target CSF Target NPR2 NPR2 Secreted Signaling -0.2183 0.0000008305246979724409 Scatter Plot
Target CSF Target MIF MIF Secreted Signaling -0.2177 0.0000008863940744565395 Scatter Plot
Source CSF Target ICAM ICAM Cell-Cell Contact -0.2167 0.0000010027367818404484 Scatter Plot
Target CSF Target APP APP Cell-Cell Contact -0.2113 0.0000018641478357079216 Scatter Plot
Target CSF Target NCAM NCAM Cell-Cell Contact -0.2007 0.000006078661690667755 Scatter Plot
Target CSF Target CSPG4 CSPG4 Cell-Cell Contact -0.2004 0.0000063036423599235295 Scatter Plot
Target CSF Target VTN VTN ECM-Receptor -0.1916 0.000015985116132999796 Scatter Plot
Target CSF Target NODAL NODAL Secreted Signaling -0.1738 0.00009332109505550532 Scatter Plot
Source CSF Source NKG2D NKG2D Cell-Cell Contact -0.1688 0.0001486604609226 Scatter Plot
Source CSF Target CD52 CD52 Cell-Cell Contact -0.1653 0.0002045865927851 Scatter Plot
Target CSF Target DMP1 DMP1 ECM-Receptor -0.1558 0.0004722306573218 Scatter Plot
Source CSF Target CCL CCL Secreted Signaling -0.1514 0.0006809684546197 Scatter Plot
Source CSF Source CLEC CLEC Cell-Cell Contact -0.1497 0.0007839188834951 Scatter Plot
Target CSF Target NRG NRG Secreted Signaling -0.1495 0.0007955803505281 Scatter Plot
Target CSF Target PTN PTN Secreted Signaling -0.1480 0.0009051558022594 Scatter Plot
Source CSF Target VCAM VCAM Cell-Cell Contact -0.1473 0.0009550163040576 Scatter Plot
Source CSF Target CXCL CXCL Secreted Signaling -0.1471 0.0009707020947176 Scatter Plot
Target CSF Target VISFATIN VISFATIN Secreted Signaling -0.1304 0.0034803333917306 Scatter Plot
Target CSF Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1297 0.0036823360595732 Scatter Plot
Target CSF Target ANGPTL ANGPTL Secreted Signaling -0.1241 0.0054637893114576 Scatter Plot
Source CSF Target CEACAM CEACAM Cell-Cell Contact -0.1227 0.0059984288617785 Scatter Plot
Target CSF Target COLLAGEN COLLAGEN ECM-Receptor -0.1226 0.0060670917707191 Scatter Plot
Source CSF Source IL1 IL1 Secreted Signaling -0.1169 0.0089108194538233 Scatter Plot
Source CSF Target GRN GRN Secreted Signaling -0.1168 0.0089354634446673 Scatter Plot
Source CSF Target COLLAGEN COLLAGEN ECM-Receptor -0.1092 0.0145435764762719 Scatter Plot
Source CSF Target IFN-II IFN-II Secreted Signaling -0.1054 0.0184408579813414 Scatter Plot
Target CSF Target PERIOSTIN PERIOSTIN Secreted Signaling -0.1045 0.0194075430914638 Scatter Plot
Source CSF Target VEGF VEGF Secreted Signaling -0.1038 0.0202759696642482 Scatter Plot

Cells that are targets of CSF from HSCs*

Cells that are source of CSF to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.