Pathway: GDF

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Secreted Signaling

Details on the GDF pathway:

Specificity Index HSPC as target: 0.066
HSPC as source: 0.341

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the GDF pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target GDF Source SEMA6 SEMA6 Cell-Cell Contact 0.1006 0.0244806569005395 Scatter Plot
Target GDF Source CD34 CD34 Cell-Cell Contact 0.1072 0.0164804484722897 Scatter Plot
Source GDF Source NOTCH NOTCH Cell-Cell Contact 0.1080 0.0156951771891833 Scatter Plot
Source GDF Source FGF FGF Secreted Signaling 0.1146 0.0103570865548337 Scatter Plot
Source GDF Source WNT WNT Secreted Signaling 0.1177 0.0084014030914863 Scatter Plot
Target GDF Source OSM OSM Secreted Signaling 0.1217 0.0064408247864568 Scatter Plot
Target GDF Source APELIN APELIN Secreted Signaling 0.1225 0.0061071888020651 Scatter Plot
Target GDF Source ICOS ICOS Cell-Cell Contact 0.1239 0.0055344365969787 Scatter Plot
Target GDF Source PTN PTN Secreted Signaling 0.1305 0.0034564564101943 Scatter Plot
Target GDF Source RANKL RANKL Secreted Signaling 0.1346 0.0025553276537672 Scatter Plot
Target GDF Source CADM CADM Cell-Cell Contact 0.1478 0.0009168260435808 Scatter Plot
Target GDF Target THBS THBS ECM-Receptor 0.1479 0.0009100659864662 Scatter Plot
Target GDF Source GP1BA GP1BA Cell-Cell Contact 0.1487 0.0008487795630443 Scatter Plot
Target GDF Source THY1 THY1 Cell-Cell Contact 0.1496 0.0007887607699676 Scatter Plot
Target GDF Source CD46 CD46 Cell-Cell Contact 0.1513 0.0006906376932311 Scatter Plot
Source GDF Source IGF IGF Secreted Signaling 0.1517 0.0006658071900043 Scatter Plot
Source GDF Source BMP BMP Secreted Signaling 0.1579 0.000394945121219 Scatter Plot
Target GDF Source FLT3 FLT3 Secreted Signaling 0.1606 0.000310816000518 Scatter Plot
Target GDF Source LAMININ LAMININ ECM-Receptor 0.1627 0.0002583205644592 Scatter Plot
Source GDF Source EPHB EPHB Cell-Cell Contact 0.1655 0.0002020092774594 Scatter Plot
Target GDF Source ANGPTL ANGPTL Secreted Signaling 0.1693 0.0001429251763781 Scatter Plot
Source GDF Source LAMININ LAMININ ECM-Receptor 0.1693 0.0001428512288083 Scatter Plot
Target GDF Source VCAM VCAM Cell-Cell Contact 0.1700 0.0001334486569454 Scatter Plot
Target GDF Source LIFR LIFR Secreted Signaling 0.1755 0.00007956971105523995 Scatter Plot
Target GDF Source BST2 BST2 Cell-Cell Contact 0.1835 0.00003652248654734408 Scatter Plot
Target GDF Source CCL CCL Secreted Signaling 0.1847 0.00003260138786306423 Scatter Plot
Target GDF Source IL2 IL2 Secreted Signaling 0.1870 0.000025674146949679125 Scatter Plot
Target GDF Source WNT WNT Secreted Signaling 0.1930 0.000013859775334928856 Scatter Plot
Source GDF Source PDGF PDGF Secreted Signaling 0.1939 0.000012644270574382913 Scatter Plot
Target GDF Source IL6 IL6 Secreted Signaling 0.1950 0.00001125494923195478 Scatter Plot
Target GDF Source CSF CSF Secreted Signaling 0.2005 0.000006245207645294321 Scatter Plot
Source GDF Source LIGHT LIGHT Secreted Signaling 0.2010 0.000005935804366345299 Scatter Plot
Target GDF Source CD39 CD39 Cell-Cell Contact 0.2010 0.000005935156487100255 Scatter Plot
Target GDF Source PROS PROS Secreted Signaling 0.2013 0.000005735656166728472 Scatter Plot
Target GDF Source SEMA3 SEMA3 Secreted Signaling 0.2059 0.000003448802300797832 Scatter Plot
Target GDF Source MK MK Secreted Signaling 0.2131 0.0000015228271255509626 Scatter Plot
Target GDF Source NOTCH NOTCH Cell-Cell Contact 0.2166 0.000001011915684490045 Scatter Plot
Target GDF Source ICAM ICAM Cell-Cell Contact 0.2213 0.0000005762839674729807 Scatter Plot
Target GDF Source LIGHT LIGHT Secreted Signaling 0.2239 0.0000004222540706157306 Scatter Plot
Target GDF Source CXCL CXCL Secreted Signaling 0.2284 0.0000002425587018796416 Scatter Plot
Target GDF Source PDGF PDGF Secreted Signaling 0.2286 0.0000002364846083324771 Scatter Plot
Target GDF Source CD45 CD45 Cell-Cell Contact 0.2294 0.0000002150953227144349 Scatter Plot
Target GDF Source CDH CDH Cell-Cell Contact 0.2308 0.00000017972731305705146 Scatter Plot
Target GDF Source IGF IGF Secreted Signaling 0.2318 0.0000001582665650874677 Scatter Plot
Source GDF Source TWEAK TWEAK Secreted Signaling 0.2325 0.0000001450199281095148 Scatter Plot
Target GDF Source LCK LCK Cell-Cell Contact 0.2338 0.0000001226214600396727 Scatter Plot
Target GDF Source TWEAK TWEAK Secreted Signaling 0.2351 0.00000010516008687697244 Scatter Plot
Target GDF Source EPHB EPHB Cell-Cell Contact 0.2427 0.000000039058468517739315 Scatter Plot
Source GDF Source JAM JAM Cell-Cell Contact 0.2434 0.000000035274577693897785 Scatter Plot
Target GDF Source BMP BMP Secreted Signaling 0.2490 0.000000016799051672505885 Scatter Plot
Target GDF Source SEMA7 SEMA7 Cell-Cell Contact 0.2511 0.000000012592531907936352 Scatter Plot
Target GDF Source COLLAGEN COLLAGEN ECM-Receptor 0.2579 0.000000004831874602542583 Scatter Plot
Target GDF Source IL16 IL16 Secreted Signaling 0.2589 0.000000004196398843915184 Scatter Plot
Target GDF Source CD1D2 CD1D2 Cell-Cell Contact 0.2606 0.000000003321932515197265 Scatter Plot
Target GDF Source MHC-I MHC-I Cell-Cell Contact 0.2628 0.0000000024064945277921807 Scatter Plot
Target GDF Source CD86 CD86 Cell-Cell Contact 0.2639 0.000000002060944625628677 Scatter Plot
Target GDF Source CX3C CX3C Secreted Signaling 0.2732 0.0000000005230473735172837 Scatter Plot
Target GDF Source ESAM ESAM Cell-Cell Contact 0.2823 0.0000000001284188296582252 Scatter Plot
Target GDF Source JAM JAM Cell-Cell Contact 0.2848 0.00000000008669926732425019 Scatter Plot
Source GDF Source GAS GAS Secreted Signaling 0.2926 0.000000000025031337061122013 Scatter Plot
Target GDF Source GAS GAS Secreted Signaling 0.2975 0.000000000011212700200396826 Scatter Plot
Target GDF Source PSAP PSAP Secreted Signaling 0.3005 0.000000000006748865060081634 Scatter Plot
Target GDF Source IL7 IL7 Secreted Signaling 0.3016 0.000000000005638757775623578 Scatter Plot
Target GDF Source ANGPT ANGPT Secreted Signaling 0.3070 0.000000000002245633565067096 Scatter Plot
Target GDF Source MHC-II MHC-II Cell-Cell Contact 0.3327 0.00000000000002164476338189107 Scatter Plot
Source GDF Source ANGPT ANGPT Secreted Signaling 0.3328 0.000000000000021456808538338483 Scatter Plot
Source GDF Source PARs PARs Secreted Signaling -0.1929 0.000014065726846519807 Scatter Plot
Source GDF Source SEMA4 SEMA4 Cell-Cell Contact -0.1718 0.0001134029690511 Scatter Plot
Target GDF Source MIF MIF Secreted Signaling -0.1651 0.000208790288796 Scatter Plot
Target GDF Source COMPLEMENT COMPLEMENT Secreted Signaling -0.1619 0.0002785298623032 Scatter Plot
Target GDF Source TGFb TGFb Secreted Signaling -0.1566 0.0004399896927478 Scatter Plot
Target GDF Source CLEC CLEC Cell-Cell Contact -0.1496 0.0007896589453226 Scatter Plot
Target GDF Source ANGPTL ANGPTL Secreted Signaling -0.1420 0.0014513856160155 Scatter Plot
Target GDF Source SEMA4 SEMA4 Cell-Cell Contact -0.1342 0.0026302630648254 Scatter Plot
Target GDF Source PARs PARs Secreted Signaling -0.1316 0.0031873946331325 Scatter Plot
Target GDF Source CD52 CD52 Cell-Cell Contact -0.1313 0.0032735790040718 Scatter Plot
Target GDF Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.1248 0.0052077619319357 Scatter Plot
Target GDF Source SELL SELL Cell-Cell Contact -0.1225 0.0060806052017966 Scatter Plot
Target GDF Source SPP1 SPP1 Secreted Signaling -0.0976 0.0291095824351087 Scatter Plot
Source GDF Target GALECTIN GALECTIN Secreted Signaling 0.0963 0.0313359497711735 Scatter Plot
Target GDF Target SELL SELL Cell-Cell Contact 0.0965 0.0310035830584463 Scatter Plot
Source GDF Target AGT AGT Secreted Signaling 0.0970 0.0300358879217313 Scatter Plot
Source GDF Target OSM OSM Secreted Signaling 0.1023 0.0220967065367689 Scatter Plot
Source GDF Target NOTCH NOTCH Cell-Cell Contact 0.1025 0.0218462212216976 Scatter Plot
Target GDF Target PDGF PDGF Secreted Signaling 0.1030 0.0212802654348286 Scatter Plot
Source GDF Source PROS PROS Secreted Signaling 0.1035 0.0205825705055237 Scatter Plot
Target GDF Target PTN PTN Secreted Signaling 0.1051 0.0187535968006973 Scatter Plot
Source GDF Source OSM OSM Secreted Signaling 0.1059 0.0178961455139813 Scatter Plot
Target GDF Target THY1 THY1 Cell-Cell Contact 0.1067 0.0170232191081351 Scatter Plot
Target GDF Target VEGF VEGF Secreted Signaling 0.1112 0.0128178885716539 Scatter Plot
Source GDF Target VEGF VEGF Secreted Signaling 0.1133 0.0112225444570425 Scatter Plot
Target GDF Target SELE SELE Cell-Cell Contact 0.1160 0.0094424955756812 Scatter Plot
Source GDF Source SEMA3 SEMA3 Secreted Signaling 0.1163 0.0092283971946327 Scatter Plot
Source GDF Target NODAL NODAL Secreted Signaling 0.1165 0.009130912463464 Scatter Plot
Target GDF Target CD45 CD45 Cell-Cell Contact 0.1184 0.0080526396946093 Scatter Plot
Target GDF Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1201 0.0071929646840681 Scatter Plot
Source GDF Target SEMA5 SEMA5 Cell-Cell Contact 0.1216 0.0064843347059122 Scatter Plot
Target GDF Target RANKL RANKL Secreted Signaling 0.1228 0.0059623412391519 Scatter Plot
Target GDF Target MK MK Secreted Signaling 0.1241 0.0054575364041764 Scatter Plot
Target GDF Target OSM OSM Secreted Signaling 0.1248 0.0052013098999848 Scatter Plot
Source GDF Target SEMA6 SEMA6 Cell-Cell Contact 0.1273 0.0043536560722395 Scatter Plot
Source GDF Target PERIOSTIN PERIOSTIN Secreted Signaling 0.1297 0.0036668533867061 Scatter Plot
Source GDF Source CD34 CD34 Cell-Cell Contact 0.1301 0.0035671350139846 Scatter Plot
Target GDF Target IL6 IL6 Secreted Signaling 0.1308 0.003378639045561 Scatter Plot
Target GDF Target AGT AGT Secreted Signaling 0.1323 0.0030416486729432 Scatter Plot
Source GDF Target NRG NRG Secreted Signaling 0.1328 0.0029369216529253 Scatter Plot
Source GDF Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1329 0.0029090626462862 Scatter Plot
Source GDF Target ANGPTL ANGPTL Secreted Signaling 0.1339 0.0026890928273773 Scatter Plot
Source GDF Target BSP BSP ECM-Receptor 0.1340 0.0026812377058285 Scatter Plot
Target GDF Target VISFATIN VISFATIN Secreted Signaling 0.1347 0.002549913258285 Scatter Plot
Source GDF Target COMPLEMENT COMPLEMENT Secreted Signaling 0.1348 0.0025159659439154 Scatter Plot
Source GDF Target THBS THBS ECM-Receptor 0.1381 0.0019711024847615 Scatter Plot
Target GDF Target CSPG4 CSPG4 Cell-Cell Contact 0.1384 0.0019159547878684 Scatter Plot
Target GDF Target COLLAGEN COLLAGEN ECM-Receptor 0.1385 0.0019064346977896 Scatter Plot
Source GDF Source CD39 CD39 Cell-Cell Contact 0.1388 0.0018708356710099 Scatter Plot
Source GDF Source CCL CCL Secreted Signaling 0.1393 0.00178831032512 Scatter Plot
Source GDF Target NPR2 NPR2 Secreted Signaling 0.1397 0.0017395717416211 Scatter Plot
Target GDF Target FN1 FN1 ECM-Receptor 0.1408 0.0015931309723217 Scatter Plot
Source GDF Target TGFb TGFb Secreted Signaling 0.1408 0.0015930666222476 Scatter Plot
Target GDF Target EPHA EPHA Cell-Cell Contact 0.1415 0.0015108822612969 Scatter Plot
Target GDF Target CD23 CD23 Cell-Cell Contact 0.1464 0.0010287397625606 Scatter Plot
Source GDF Target DMP1 DMP1 ECM-Receptor 0.1469 0.0009859690381154 Scatter Plot
Target GDF Target CADM CADM Cell-Cell Contact 0.1478 0.0009168260435808 Scatter Plot
Source GDF Target EPHB EPHB Cell-Cell Contact 0.1488 0.0008438418435226 Scatter Plot
Source GDF Target SELL SELL Cell-Cell Contact 0.1497 0.0007870742325443 Scatter Plot
Target GDF Target SPP1 SPP1 Secreted Signaling 0.1504 0.0007400261982609 Scatter Plot
Target GDF Target ANGPTL ANGPTL Secreted Signaling 0.1525 0.0006240297014255 Scatter Plot
Target GDF Target GALECTIN GALECTIN Secreted Signaling 0.1534 0.000579363132995 Scatter Plot
Target GDF Target PARs PARs Secreted Signaling 0.1577 0.0004015959072798 Scatter Plot
Source GDF Target VTN VTN ECM-Receptor 0.1583 0.0003817544030247 Scatter Plot
Source GDF Target PARs PARs Secreted Signaling 0.1589 0.000360225342189 Scatter Plot
Source GDF Target VWF VWF ECM-Receptor 0.1601 0.0003258916535553 Scatter Plot
Source GDF Source PSAP PSAP Secreted Signaling 0.1619 0.0002779577987758 Scatter Plot
Source GDF Source LIFR LIFR Secreted Signaling 0.1620 0.0002760323469407 Scatter Plot
Target GDF Target SEMA7 SEMA7 Cell-Cell Contact 0.1647 0.0002155897848157 Scatter Plot
Source GDF Source CD1D2 CD1D2 Cell-Cell Contact 0.1651 0.0002087656728357 Scatter Plot
Source GDF Target FN1 FN1 ECM-Receptor 0.1656 0.0001995638452342 Scatter Plot
Source GDF Source CSF CSF Secreted Signaling 0.1678 0.00016390106223 Scatter Plot
Source GDF Target VISFATIN VISFATIN Secreted Signaling 0.1681 0.000159406815983 Scatter Plot
Source GDF Source IL16 IL16 Secreted Signaling 0.1697 0.0001375275204432 Scatter Plot
Source GDF Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.1715 0.0001164663006451 Scatter Plot
Source GDF Target ACTIVIN ACTIVIN Secreted Signaling 0.1716 0.0001151408116654 Scatter Plot
Source GDF Target PTN PTN Secreted Signaling 0.1729 0.0001019436086002 Scatter Plot
Target GDF Target IL1 IL1 Secreted Signaling 0.1734 0.00009708751782900191 Scatter Plot
Target GDF Target VWF VWF ECM-Receptor 0.1760 0.00007576369964993364 Scatter Plot
Source GDF Source CX3C CX3C Secreted Signaling 0.1762 0.00007438074126134305 Scatter Plot
Target GDF Target IGF IGF Secreted Signaling 0.1764 0.00007283780364725112 Scatter Plot
Source GDF Target IGF IGF Secreted Signaling 0.1775 0.00006571213357254671 Scatter Plot
Target GDF Target SEMA3 SEMA3 Secreted Signaling 0.1797 0.00005330273155106981 Scatter Plot
Source GDF Source PTN PTN Secreted Signaling 0.1816 0.00004434583121236365 Scatter Plot
Target GDF Target VTN VTN ECM-Receptor 0.1816 0.000044039961591962655 Scatter Plot
Source GDF Source CDH CDH Cell-Cell Contact 0.1823 0.00004124496429881596 Scatter Plot
Source GDF Target CDH CDH Cell-Cell Contact 0.1823 0.00004124496429881596 Scatter Plot
Source GDF Target ANGPT ANGPT Secreted Signaling 0.1868 0.000026391268914967905 Scatter Plot
Source GDF Source VEGF VEGF Secreted Signaling 0.1874 0.00002466549541013201 Scatter Plot
Source GDF Target LAMININ LAMININ ECM-Receptor 0.1875 0.000024341846151225397 Scatter Plot
Source GDF Target SPP1 SPP1 Secreted Signaling 0.1877 0.000023920002080643527 Scatter Plot
Source GDF Target MK MK Secreted Signaling 0.1908 0.000017489774310955307 Scatter Plot
Target GDF Target KIT KIT Secreted Signaling 0.1921 0.000015201883145605527 Scatter Plot
Source GDF Target JAM JAM Cell-Cell Contact 0.1936 0.000013077301769966732 Scatter Plot
Source GDF Target SEMA7 SEMA7 Cell-Cell Contact 0.1965 0.000009586835695039954 Scatter Plot
Source GDF Source IL2 IL2 Secreted Signaling 0.2026 0.000004941290587271551 Scatter Plot
Source GDF Source IL6 IL6 Secreted Signaling 0.2045 0.000004002495445359157 Scatter Plot
Target GDF Target BSP BSP ECM-Receptor 0.2051 0.00000375630390811066 Scatter Plot
Target GDF Target TENASCIN TENASCIN ECM-Receptor 0.2054 0.000003659220533622128 Scatter Plot
Target GDF Target PERIOSTIN PERIOSTIN Secreted Signaling 0.2058 0.000003469917486652657 Scatter Plot
Target GDF Target DMP1 DMP1 ECM-Receptor 0.2085 0.0000025657173394141705 Scatter Plot
Source GDF Source VCAM VCAM Cell-Cell Contact 0.2095 0.000002308164774338266 Scatter Plot
Source GDF Target CD200 CD200 Cell-Cell Contact 0.2116 0.0000018036225981031985 Scatter Plot
Source GDF Source THY1 THY1 Cell-Cell Contact 0.2124 0.0000016417531523474286 Scatter Plot
Target GDF Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.2136 0.0000014338774987117347 Scatter Plot
Target GDF Target LAMININ LAMININ ECM-Receptor 0.2136 0.000001426804935857604 Scatter Plot
Target GDF Target NRG NRG Secreted Signaling 0.2140 0.000001367454294382616 Scatter Plot
Source GDF Target FGF FGF Secreted Signaling 0.2182 0.000000838300065763154 Scatter Plot
Source GDF Source FLT3 FLT3 Secreted Signaling 0.2187 0.0000007889765698509838 Scatter Plot
Source GDF Source CXCL CXCL Secreted Signaling 0.2193 0.0000007337128175413596 Scatter Plot
Source GDF Target TENASCIN TENASCIN ECM-Receptor 0.2219 0.0000005366617346004012 Scatter Plot
Target GDF Target CD34 CD34 Cell-Cell Contact 0.2242 0.0000004092219725649502 Scatter Plot
Source GDF Source CD45 CD45 Cell-Cell Contact 0.2251 0.0000003671863246754067 Scatter Plot
Source GDF Target CD22 CD22 Cell-Cell Contact 0.2251 0.000000367186324675406 Scatter Plot
Source GDF Source ICAM ICAM Cell-Cell Contact 0.2283 0.0000002462917668220419 Scatter Plot
Target GDF Target CD22 CD22 Cell-Cell Contact 0.2294 0.0000002150953227144349 Scatter Plot
Source GDF Target CD39 CD39 Cell-Cell Contact 0.2301 0.00000019753700328301765 Scatter Plot
Target GDF Target ANGPT ANGPT Secreted Signaling 0.2302 0.00000019441623228219089 Scatter Plot
Target GDF Target CDH CDH Cell-Cell Contact 0.2308 0.00000017972731305705146 Scatter Plot
Source GDF Target KIT KIT Secreted Signaling 0.2309 0.00000017905781114586505 Scatter Plot
Source GDF Source LCK LCK Cell-Cell Contact 0.2358 0.00000009538038143398404 Scatter Plot
Target GDF Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2364 0.0000000886933193902268 Scatter Plot
Source GDF Target BMP BMP Secreted Signaling 0.2396 0.000000058672704718981256 Scatter Plot
Source GDF Source CD86 CD86 Cell-Cell Contact 0.2408 0.00000004986660634534382 Scatter Plot
Source GDF Source IL7 IL7 Secreted Signaling 0.2421 0.00000004219486427842293 Scatter Plot
Target GDF Target EPHB EPHB Cell-Cell Contact 0.2466 0.000000023028633887396598 Scatter Plot
Source GDF Target BAFF BAFF Secreted Signaling 0.2466 0.00000002296763577813134 Scatter Plot
Target GDF Target JAM JAM Cell-Cell Contact 0.2551 0.0000000071552964422798865 Scatter Plot
Source GDF Target SLURP SLURP Secreted Signaling 0.2597 0.000000003780011194478627 Scatter Plot
Source GDF Source BST2 BST2 Cell-Cell Contact 0.2612 0.000000003047295716265196 Scatter Plot
Target GDF Target ncWNT ncWNT Secreted Signaling 0.2635 0.0000000021678492339110028 Scatter Plot
Source GDF Target APP APP Cell-Cell Contact 0.2639 0.0000000020643836744502332 Scatter Plot
Target GDF Target SEMA4 SEMA4 Cell-Cell Contact 0.2667 0.0000000013657503075510118 Scatter Plot
Source GDF Source MK MK Secreted Signaling 0.2668 0.0000000013556648002834722 Scatter Plot
Source GDF Target MIF MIF Secreted Signaling 0.2742 0.000000000450100337863014 Scatter Plot
Target GDF Target APP APP Cell-Cell Contact 0.2802 0.00000000017895470009938238 Scatter Plot
Source GDF Source GAS GAS Secreted Signaling 0.2804 0.00000000017373144593492875 Scatter Plot
Source GDF Target ncWNT ncWNT Secreted Signaling 0.2812 0.00000000015430877144122794 Scatter Plot
Target GDF Target CD39 CD39 Cell-Cell Contact 0.2814 0.00000000014950029556744215 Scatter Plot
Source GDF Source MHC-I MHC-I Cell-Cell Contact 0.2817 0.00000000014146655671194622 Scatter Plot
Target GDF Target ESAM ESAM Cell-Cell Contact 0.2823 0.00000000012841882965822375 Scatter Plot
Target GDF Target FGF FGF Secreted Signaling 0.2856 0.00000000007675148449424579 Scatter Plot
Target GDF Target NPR2 NPR2 Secreted Signaling 0.2883 0.000000000049827216370611326 Scatter Plot
Target GDF Target CD200 CD200 Cell-Cell Contact 0.2934 0.00000000002186184783517191 Scatter Plot
Source GDF Source SEMA7 SEMA7 Cell-Cell Contact 0.2942 0.000000000019239041266523818 Scatter Plot
Target GDF Target SLURP SLURP Secreted Signaling 0.2975 0.000000000011154411729436809 Scatter Plot
Target GDF Target MIF MIF Secreted Signaling 0.3009 0.000000000006310324549933689 Scatter Plot
Target GDF Target BAFF BAFF Secreted Signaling 0.3019 0.000000000005333612226943369 Scatter Plot
Source GDF Source ESAM ESAM Cell-Cell Contact 0.3028 0.000000000004590693573665781 Scatter Plot
Source GDF Target ESAM ESAM Cell-Cell Contact 0.3028 0.000000000004590693573665781 Scatter Plot
Source GDF Target SEMA4 SEMA4 Cell-Cell Contact 0.3034 0.000000000004144237951770372 Scatter Plot
Target GDF Target WNT WNT Secreted Signaling 0.3058 0.000000000002759893556297745 Scatter Plot
Target GDF Target SEMA6 SEMA6 Cell-Cell Contact 0.3081 0.000000000001850047428282131 Scatter Plot
Source GDF Target WNT WNT Secreted Signaling 0.3110 0.0000000000011335214657984354 Scatter Plot
Target GDF Target SEMA5 SEMA5 Cell-Cell Contact 0.3134 0.000000000000738154268343705 Scatter Plot
Source GDF Target CD34 CD34 Cell-Cell Contact 0.3146 0.0000000000005970799441443086 Scatter Plot
Source GDF Source COLLAGEN COLLAGEN ECM-Receptor 0.3331 0.000000000000020316582006109225 Scatter Plot
Source GDF Source MHC-II MHC-II Cell-Cell Contact 0.3502 0.000000000000000718241120300008 Scatter Plot
Source GDF Source CLEC CLEC Cell-Cell Contact -0.1725 0.0001055708196939 Scatter Plot
Source GDF Source COMPLEMENT COMPLEMENT Secreted Signaling -0.1680 0.0001604924820766 Scatter Plot
Source GDF Source VISTA VISTA Cell-Cell Contact -0.1624 0.0002659508559078 Scatter Plot
Source GDF Source CD52 CD52 Cell-Cell Contact -0.1607 0.0003087407897554 Scatter Plot
Source GDF Source SELL SELL Cell-Cell Contact -0.1592 0.0003531688455176 Scatter Plot
Source GDF Target CXCL CXCL Secreted Signaling -0.1462 0.0010431434410961 Scatter Plot
Target GDF Target CXCL CXCL Secreted Signaling -0.1415 0.0015073832347833 Scatter Plot
Source GDF Target CSF CSF Secreted Signaling -0.1356 0.0023714952241939 Scatter Plot
Source GDF Target ICAM ICAM Cell-Cell Contact -0.1287 0.0039522031128385 Scatter Plot
Source GDF Target IL17 IL17 Secreted Signaling -0.1279 0.0041709034571148 Scatter Plot
Source GDF Target CLEC CLEC Cell-Cell Contact -0.1244 0.0053271016249574 Scatter Plot
Source GDF Target CD52 CD52 Cell-Cell Contact -0.1242 0.0054263861783967 Scatter Plot
Source GDF Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.1236 0.0056586643620437 Scatter Plot
Source GDF Source BAFF BAFF Secreted Signaling -0.1158 0.0095528766663297 Scatter Plot
Source GDF Target CEACAM CEACAM Cell-Cell Contact -0.1142 0.0105752951910626 Scatter Plot
Source GDF Target ANNEXIN ANNEXIN Secreted Signaling -0.1125 0.0118574879259477 Scatter Plot
Source GDF Target CCL CCL Secreted Signaling -0.1101 0.0138000258975144 Scatter Plot
Target GDF Target CD52 CD52 Cell-Cell Contact -0.1080 0.0157375199728874 Scatter Plot
Source GDF Source NCAM NCAM Cell-Cell Contact -0.1065 0.0172253737255337 Scatter Plot
Source GDF Source SPP1 SPP1 Secreted Signaling -0.1058 0.0179860637406717 Scatter Plot
Source GDF Target GRN GRN Secreted Signaling -0.1021 0.0224631305341855 Scatter Plot
Source GDF Target COLLAGEN COLLAGEN ECM-Receptor -0.1020 0.0224858800783266 Scatter Plot
Source GDF Target VCAM VCAM Cell-Cell Contact -0.1018 0.0227908808185105 Scatter Plot
Target GDF Target ICAM ICAM Cell-Cell Contact -0.0990 0.0268318319228998 Scatter Plot

Cells that are targets of GDF from HSCs*

Cells that are source of GDF to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.