Pathway: GRN

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Secreted Signaling

Details on the GRN pathway:

Specificity Index HSPC as target: 0.451
HSPC as source: 0.301

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the GRN pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target GRN Target CSF CSF Secreted Signaling 0.0976 0.0291446385928428 Scatter Plot
Source GRN Source NT NT Secreted Signaling 0.1035 0.0206105827316378 Scatter Plot
Target GRN Source TNF TNF Secreted Signaling 0.1054 0.0183670778653308 Scatter Plot
Target GRN Target CD23 CD23 Cell-Cell Contact 0.1085 0.0151802089741495 Scatter Plot
Target GRN Source PARs PARs Secreted Signaling 0.1112 0.0128487495270923 Scatter Plot
Source GRN Source ncWNT ncWNT Secreted Signaling 0.1117 0.0124319270454605 Scatter Plot
Target GRN Source CLEC CLEC Cell-Cell Contact 0.1124 0.011904174651798 Scatter Plot
Target GRN Target COMPLEMENT COMPLEMENT Secreted Signaling 0.1159 0.0095140337390642 Scatter Plot
Target GRN Target COLLAGEN COLLAGEN ECM-Receptor 0.1161 0.0093848122340905 Scatter Plot
Target GRN Target CXCL CXCL Secreted Signaling 0.1171 0.0087830731983497 Scatter Plot
Target GRN Target VCAM VCAM Cell-Cell Contact 0.1175 0.0085520903908347 Scatter Plot
Target GRN Source NCAM NCAM Cell-Cell Contact 0.1180 0.0082653054525131 Scatter Plot
Target GRN Target CEACAM CEACAM Cell-Cell Contact 0.1201 0.0071739221677573 Scatter Plot
Target GRN Source NKG2D NKG2D Cell-Cell Contact 0.1257 0.0048950275047296 Scatter Plot
Target GRN Source SELL SELL Cell-Cell Contact 0.1263 0.0046651078879553 Scatter Plot
Target GRN Source VISTA VISTA Cell-Cell Contact 0.1266 0.0045702885607561 Scatter Plot
Target GRN Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1282 0.0040984613485539 Scatter Plot
Target GRN Source APP APP Cell-Cell Contact 0.1296 0.0036892635745457 Scatter Plot
Target GRN Target ICAM ICAM Cell-Cell Contact 0.1299 0.003628467412875 Scatter Plot
Target GRN Target NCAM NCAM Cell-Cell Contact 0.1343 0.0026153053028172 Scatter Plot
Target GRN Source SPP1 SPP1 Secreted Signaling 0.1378 0.0020070082001532 Scatter Plot
Target GRN Target SELE SELE Cell-Cell Contact 0.1390 0.0018356943563347 Scatter Plot
Target GRN Source COMPLEMENT COMPLEMENT Secreted Signaling 0.1413 0.0015322750998949 Scatter Plot
Target GRN Target LAIR1 LAIR1 Cell-Cell Contact 0.1424 0.0014110194660724 Scatter Plot
Target GRN Target GALECTIN GALECTIN Secreted Signaling 0.1450 0.0011522918077719 Scatter Plot
Target GRN Source SEMA4 SEMA4 Cell-Cell Contact 0.1454 0.0011111141585149 Scatter Plot
Source GRN Source LAMININ LAMININ ECM-Receptor 0.1459 0.0010701123025793 Scatter Plot
Source GRN Source NOTCH NOTCH Cell-Cell Contact 0.1563 0.0004534084847722 Scatter Plot
Target GRN Target CD52 CD52 Cell-Cell Contact 0.1629 0.0002542732789965 Scatter Plot
Target GRN Source CD52 CD52 Cell-Cell Contact 0.1648 0.0002151319806937 Scatter Plot
Target GRN Source ANNEXIN ANNEXIN Secreted Signaling 0.1665 0.0001833755941865 Scatter Plot
Target GRN Source LAIR1 LAIR1 Cell-Cell Contact 0.1721 0.0001102581175466 Scatter Plot
Source GRN Source PARs PARs Secreted Signaling 0.2503 0.00000001394147934049022 Scatter Plot
Source GRN Source SEMA4 SEMA4 Cell-Cell Contact 0.2621 0.000000002676839224520388 Scatter Plot
Source GRN Source GALECTIN GALECTIN Secreted Signaling -0.4637 0.0000000000000000000000000004990991693661682 Scatter Plot
Source GRN Source ANGPTL ANGPTL Secreted Signaling -0.2840 0.00000000009954481014254752 Scatter Plot
Source GRN Source VCAM VCAM Cell-Cell Contact -0.2748 0.000000000407939479628518 Scatter Plot
Source GRN Source TGFb TGFb Secreted Signaling -0.2163 0.000001044068786627427 Scatter Plot
Source GRN Source FGF FGF Secreted Signaling -0.2157 0.000001117673728804651 Scatter Plot
Source GRN Source VEGF VEGF Secreted Signaling -0.1914 0.000016425406840847164 Scatter Plot
Target GRN Target CD34 CD34 Cell-Cell Contact -0.1870 0.000025672715617017383 Scatter Plot
Source GRN Source CCL CCL Secreted Signaling -0.1794 0.00005478426787057622 Scatter Plot
Target GRN Source BMP BMP Secreted Signaling -0.1724 0.0001067260890717 Scatter Plot
Target GRN Source VCAM VCAM Cell-Cell Contact -0.1704 0.0001291429938901 Scatter Plot
Target GRN Target MK MK Secreted Signaling -0.1669 0.0001768373995992 Scatter Plot
Source GRN Source ANGPT ANGPT Secreted Signaling -0.1649 0.0002120988837256 Scatter Plot
Target GRN Source JAM JAM Cell-Cell Contact -0.1564 0.0004461706599805 Scatter Plot
Target GRN Source ICAM ICAM Cell-Cell Contact -0.1494 0.0008020788264307 Scatter Plot
Target GRN Source CD1D2 CD1D2 Cell-Cell Contact -0.1456 0.0010942602109673 Scatter Plot
Target GRN Source BST2 BST2 Cell-Cell Contact -0.1380 0.0019780622134326 Scatter Plot
Target GRN Target JAM JAM Cell-Cell Contact -0.1371 0.0021160342859531 Scatter Plot
Target GRN Target WNT WNT Secreted Signaling -0.1362 0.0022654768983553 Scatter Plot
Target GRN Target AGT AGT Secreted Signaling -0.1362 0.0022724227760357 Scatter Plot
Target GRN Target ncWNT ncWNT Secreted Signaling -0.1356 0.0023766042624273 Scatter Plot
Target GRN Target FN1 FN1 ECM-Receptor -0.1354 0.0024108893987127 Scatter Plot
Target GRN Target PTN PTN Secreted Signaling -0.1352 0.0024429638481956 Scatter Plot
Target GRN Target TWEAK TWEAK Secreted Signaling -0.1352 0.0024517198596838 Scatter Plot
Target GRN Target SEMA7 SEMA7 Cell-Cell Contact -0.1331 0.0028564691108566 Scatter Plot
Target GRN Source APELIN APELIN Secreted Signaling -0.1312 0.0032955642888475 Scatter Plot
Target GRN Source SEMA7 SEMA7 Cell-Cell Contact -0.1308 0.0033896490169396 Scatter Plot
Target GRN Target CD39 CD39 Cell-Cell Contact -0.1306 0.0034328322192564 Scatter Plot
Target GRN Target SEMA5 SEMA5 Cell-Cell Contact -0.1306 0.0034400250861296 Scatter Plot
Target GRN Source ANGPT ANGPT Secreted Signaling -0.1300 0.0035928081651523 Scatter Plot
Target GRN Target ESAM ESAM Cell-Cell Contact -0.1296 0.0036875882126626 Scatter Plot
Target GRN Source ESAM ESAM Cell-Cell Contact -0.1296 0.0036875882126626 Scatter Plot
Target GRN Target EPHA EPHA Cell-Cell Contact -0.1294 0.0037445760807218 Scatter Plot
Target GRN Source GALECTIN GALECTIN Secreted Signaling -0.1290 0.0038663281416608 Scatter Plot
Target GRN Target SLURP SLURP Secreted Signaling -0.1288 0.0039096302821265 Scatter Plot
Target GRN Target VTN VTN ECM-Receptor -0.1278 0.0041983565974391 Scatter Plot
Target GRN Target VWF VWF ECM-Receptor -0.1258 0.0048302251403122 Scatter Plot
Target GRN Target TENASCIN TENASCIN ECM-Receptor -0.1258 0.0048514849737049 Scatter Plot
Target GRN Target ANGPT ANGPT Secreted Signaling -0.1256 0.0049274600232648 Scatter Plot
Target GRN Source MHC-I MHC-I Cell-Cell Contact -0.1250 0.0051277005753898 Scatter Plot
Target GRN Source TWEAK TWEAK Secreted Signaling -0.1248 0.0051812856889249 Scatter Plot
Target GRN Source LIFR LIFR Secreted Signaling -0.1247 0.0052448887013923 Scatter Plot
Target GRN Source FLT3 FLT3 Secreted Signaling -0.1232 0.0057967537179872 Scatter Plot
Source GRN Source CD34 CD34 Cell-Cell Contact -0.1223 0.0061837507869019 Scatter Plot
Target GRN Target IGF IGF Secreted Signaling -0.1217 0.0064486721517923 Scatter Plot
Target GRN Source PDGF PDGF Secreted Signaling -0.1205 0.0069802975953271 Scatter Plot
Target GRN Target KIT KIT Secreted Signaling -0.1202 0.007129550145815 Scatter Plot
Target GRN Target EPHB EPHB Cell-Cell Contact -0.1201 0.0071706322540854 Scatter Plot
Target GRN Target DMP1 DMP1 ECM-Receptor -0.1190 0.0077435560355694 Scatter Plot
Target GRN Target PDGF PDGF Secreted Signaling -0.1188 0.0078236744961399 Scatter Plot
Target GRN Source CDH CDH Cell-Cell Contact -0.1187 0.0079080865150549 Scatter Plot
Target GRN Target CDH CDH Cell-Cell Contact -0.1187 0.0079080865150549 Scatter Plot
Target GRN Target FGF FGF Secreted Signaling -0.1185 0.0079988044668961 Scatter Plot
Target GRN Source CXCL CXCL Secreted Signaling -0.1184 0.0080632639535272 Scatter Plot
Target GRN Source MHC-II MHC-II Cell-Cell Contact -0.1182 0.0081267961580021 Scatter Plot
Target GRN Target SEMA4 SEMA4 Cell-Cell Contact -0.1182 0.0081333999337076 Scatter Plot
Target GRN Source CSF CSF Secreted Signaling -0.1168 0.0089354634446673 Scatter Plot
Target GRN Source COLLAGEN COLLAGEN ECM-Receptor -0.1165 0.0091367643016219 Scatter Plot
Target GRN Target NPR2 NPR2 Secreted Signaling -0.1161 0.0093586358529515 Scatter Plot
Target GRN Source VEGF VEGF Secreted Signaling -0.1154 0.0097983964501598 Scatter Plot
Target GRN Target APP APP Cell-Cell Contact -0.1153 0.009851236351109 Scatter Plot
Target GRN Source THY1 THY1 Cell-Cell Contact -0.1146 0.0103547405628781 Scatter Plot
Target GRN Target ACTIVIN ACTIVIN Secreted Signaling -0.1144 0.0104479020211301 Scatter Plot
Target GRN Source ICOS ICOS Cell-Cell Contact -0.1144 0.0104902495464416 Scatter Plot
Target GRN Target BSP BSP ECM-Receptor -0.1141 0.0106382927098529 Scatter Plot
Target GRN Target SEMA6 SEMA6 Cell-Cell Contact -0.1136 0.0110367690502711 Scatter Plot
Target GRN Source CD86 CD86 Cell-Cell Contact -0.1133 0.0112063681907525 Scatter Plot
Target GRN Target VISFATIN VISFATIN Secreted Signaling -0.1105 0.0133844916288802 Scatter Plot
Target GRN Source GAS GAS Secreted Signaling -0.1101 0.0138092047631264 Scatter Plot
Target GRN Source GP1BA GP1BA Cell-Cell Contact -0.1098 0.014003303359976 Scatter Plot
Target GRN Source EPHB EPHB Cell-Cell Contact -0.1095 0.0143037731998148 Scatter Plot
Target GRN Source LCK LCK Cell-Cell Contact -0.1095 0.0143053878960596 Scatter Plot
Target GRN Source NT NT Secreted Signaling -0.1092 0.0146057284304836 Scatter Plot
Target GRN Source IGF IGF Secreted Signaling -0.1086 0.0151013464230228 Scatter Plot
Target GRN Source CX3C CX3C Secreted Signaling -0.1081 0.0155508114905997 Scatter Plot
Target GRN Source LAMININ LAMININ ECM-Receptor -0.1075 0.0161576367084444 Scatter Plot
Target GRN Source PROS PROS Secreted Signaling -0.1069 0.0167567563612741 Scatter Plot
Target GRN Source LIGHT LIGHT Secreted Signaling -0.1067 0.0169759918929123 Scatter Plot
Target GRN Target LAMININ LAMININ ECM-Receptor -0.1058 0.0179505053837953 Scatter Plot
Target GRN Target PERIOSTIN PERIOSTIN Secreted Signaling -0.1042 0.0198025876071974 Scatter Plot
Target GRN Source IL2 IL2 Secreted Signaling -0.1039 0.0200962430613445 Scatter Plot
Target GRN Target CADM CADM Cell-Cell Contact -0.1036 0.0205410360714534 Scatter Plot
Target GRN Source CADM CADM Cell-Cell Contact -0.1036 0.0205410360714535 Scatter Plot
Target GRN Source PTN PTN Secreted Signaling -0.1025 0.0219207270243455 Scatter Plot
Target GRN Source FGF FGF Secreted Signaling -0.1024 0.0220661003389977 Scatter Plot
Target GRN Source GDF GDF Secreted Signaling -0.1021 0.0224631305341855 Scatter Plot
Target GRN Source ANGPTL ANGPTL Secreted Signaling -0.1013 0.0235485154252489 Scatter Plot
Target GRN Source THBS THBS ECM-Receptor -0.1002 0.0250316536888513 Scatter Plot
Target GRN Source SEMA3 SEMA3 Secreted Signaling -0.0999 0.0254330219336197 Scatter Plot
Target GRN Target SEMA3 SEMA3 Secreted Signaling -0.0998 0.0256552693250302 Scatter Plot
Target GRN Target VEGF VEGF Secreted Signaling -0.0996 0.0260026304280625 Scatter Plot
Target GRN Target NOTCH NOTCH Cell-Cell Contact -0.0993 0.0263946760039753 Scatter Plot
Target GRN Target ANGPTL ANGPTL Secreted Signaling -0.0981 0.0282450695234678 Scatter Plot
Target GRN Target IL1 IL1 Secreted Signaling -0.0981 0.0282773880728319 Scatter Plot
Source GRN Source PECAM1 PECAM1 Cell-Cell Contact -0.0973 0.0296271071568478 Scatter Plot
Target GRN Source IL7 IL7 Secreted Signaling -0.0961 0.0316764586063504 Scatter Plot
Target GRN Target IL1 IL1 Secreted Signaling 0.0973 0.0295584781758416 Scatter Plot
Target GRN Target CD86 CD86 Cell-Cell Contact 0.1007 0.0243818994630157 Scatter Plot
Target GRN Target THY1 THY1 Cell-Cell Contact 0.1022 0.022313929803167 Scatter Plot
Target GRN Target CLEC CLEC Cell-Cell Contact 0.1039 0.0201765517901539 Scatter Plot
Target GRN Target IFN-II IFN-II Secreted Signaling 0.1069 0.0168330744881915 Scatter Plot
Source GRN Target VEGF VEGF Secreted Signaling 0.1081 0.0156059760604063 Scatter Plot
Source GRN Source FN1 FN1 ECM-Receptor 0.1082 0.0155135333837792 Scatter Plot
Source GRN Target CD86 CD86 Cell-Cell Contact 0.1177 0.008441482162284 Scatter Plot
Source GRN Target LAIR1 LAIR1 Cell-Cell Contact 0.1286 0.0039697645323512 Scatter Plot
Source GRN Target BST2 BST2 Cell-Cell Contact 0.1286 0.0039697645323512 Scatter Plot
Source GRN Source CADM CADM Cell-Cell Contact 0.1305 0.0034637661875086 Scatter Plot
Source GRN Target CADM CADM Cell-Cell Contact 0.1305 0.0034637661875086 Scatter Plot
Source GRN Target RANKL RANKL Secreted Signaling 0.1355 0.0023968026228368 Scatter Plot
Source GRN Source CCL CCL Secreted Signaling 0.1368 0.0021714487957876 Scatter Plot
Source GRN Source CD39 CD39 Cell-Cell Contact 0.1369 0.0021523698543039 Scatter Plot
Target GRN Target BST2 BST2 Cell-Cell Contact 0.1424 0.0014110194660724 Scatter Plot
Source GRN Source CLEC CLEC Cell-Cell Contact 0.1437 0.001274207490294 Scatter Plot
Target GRN Target GALECTIN GALECTIN Secreted Signaling 0.1439 0.0012490646748321 Scatter Plot
Source GRN Target IL6 IL6 Secreted Signaling 0.1450 0.0011463327659365 Scatter Plot
Source GRN Target SEMA4 SEMA4 Cell-Cell Contact 0.1525 0.0006214792519803 Scatter Plot
Source GRN Target OSM OSM Secreted Signaling 0.1541 0.0005466207704265 Scatter Plot
Source GRN Target CXCL CXCL Secreted Signaling 0.1575 0.0004059743610869 Scatter Plot
Source GRN Target SELE SELE Cell-Cell Contact 0.1611 0.0002972891454431 Scatter Plot
Source GRN Target COLLAGEN COLLAGEN ECM-Receptor 0.1642 0.0002269313567002 Scatter Plot
Target GRN Target CCL CCL Secreted Signaling 0.1835 0.00003664414591363134 Scatter Plot
Source GRN Target CSF CSF Secreted Signaling 0.1941 0.000012404753686911604 Scatter Plot
Target GRN Target ANNEXIN ANNEXIN Secreted Signaling 0.1978 0.000008313122395641585 Scatter Plot
Source GRN Source TNF TNF Secreted Signaling 0.2030 0.000004762414717623053 Scatter Plot
Source GRN Source CD45 CD45 Cell-Cell Contact 0.2071 0.000003014373442715584 Scatter Plot
Source GRN Target CD22 CD22 Cell-Cell Contact 0.2071 0.000003014373442715584 Scatter Plot
Source GRN Target SEMA3 SEMA3 Secreted Signaling 0.2093 0.0000023589011823820367 Scatter Plot
Source GRN Target ANNEXIN ANNEXIN Secreted Signaling 0.2238 0.000000427030291477547 Scatter Plot
Source GRN Source SPP1 SPP1 Secreted Signaling 0.2300 0.0000001996910770039683 Scatter Plot
Source GRN Source IL16 IL16 Secreted Signaling 0.2336 0.0000001266641443696022 Scatter Plot
Source GRN Source PSAP PSAP Secreted Signaling 0.2345 0.0000001127524801929903 Scatter Plot
Source GRN Target IFN-II IFN-II Secreted Signaling 0.2353 0.00000010177875951803557 Scatter Plot
Source GRN Target IL1 IL1 Secreted Signaling 0.2384 0.0000000684935231100679 Scatter Plot
Source GRN Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2397 0.00000005740430951029469 Scatter Plot
Source GRN Target VCAM VCAM Cell-Cell Contact 0.2430 0.00000003734254859108128 Scatter Plot
Source GRN Target ANGPTL ANGPTL Secreted Signaling 0.2582 0.000000004632494534521137 Scatter Plot
Source GRN Target CLEC CLEC Cell-Cell Contact 0.2585 0.000000004487961158829931 Scatter Plot
Source GRN Source LAIR1 LAIR1 Cell-Cell Contact 0.2619 0.000000002729930254372458 Scatter Plot
Source GRN Source BAFF BAFF Secreted Signaling 0.2725 0.0000000005797547707538895 Scatter Plot
Source GRN Target JAM JAM Cell-Cell Contact 0.2784 0.0000000002357262512253664 Scatter Plot
Source GRN Target GALECTIN GALECTIN Secreted Signaling 0.2828 0.0000000001186050345881566 Scatter Plot
Source GRN Source SELL SELL Cell-Cell Contact 0.2871 0.00000000006081649831186392 Scatter Plot
Source GRN Target CCL CCL Secreted Signaling 0.3011 0.000000000006155787342091733 Scatter Plot
Source GRN Target CD52 CD52 Cell-Cell Contact 0.3024 0.000000000004946601085467651 Scatter Plot
Source GRN Target ICAM ICAM Cell-Cell Contact 0.3084 0.0000000000017597673653752436 Scatter Plot
Source GRN Target SELPLG SELPLG Cell-Cell Contact 0.3092 0.0000000000015266158974457392 Scatter Plot
Source GRN Target CEACAM CEACAM Cell-Cell Contact 0.3277 0.000000000000055902357440931643 Scatter Plot
Source GRN Source CD52 CD52 Cell-Cell Contact 0.3483 0.0000000000000010429956427044238 Scatter Plot
Source GRN Source NCAM NCAM Cell-Cell Contact 0.3580 0.00000000000000014527616929754374 Scatter Plot
Source GRN Target COMPLEMENT COMPLEMENT Secreted Signaling 0.3672 0.000000000000000021014916668924997 Scatter Plot
Source GRN Source COMPLEMENT COMPLEMENT Secreted Signaling 0.3863 0.00000000000000000030489165410041122 Scatter Plot
Source GRN Target NCAM NCAM Cell-Cell Contact 0.3990 0.000000000000000000015705693410911722 Scatter Plot
Source GRN Target CD23 CD23 Cell-Cell Contact 0.4143 0.00000000000000000000036194362241135047 Scatter Plot
Source GRN Target THY1 THY1 Cell-Cell Contact 0.4214 0.00000000000000000000005958752138672566 Scatter Plot
Source GRN Source ANNEXIN ANNEXIN Secreted Signaling 0.4623 0.0000000000000000000000000007642901268485861 Scatter Plot
Source GRN Source VISTA VISTA Cell-Cell Contact 0.4874 0.0000000000000000000000000000003324828821815304 Scatter Plot
Source GRN Source APP APP Cell-Cell Contact 0.4966 0.000000000000000000000000000000016791882352683682 Scatter Plot
Source GRN Source GALECTIN GALECTIN Secreted Signaling -0.4637 0.0000000000000000000000000004990991693661682 Scatter Plot
Source GRN Target MK MK Secreted Signaling -0.3600 0.00000000000000009610631002331836 Scatter Plot
Source GRN Target PTN PTN Secreted Signaling -0.2866 0.00000000006586157229612 Scatter Plot
Source GRN Target KIT KIT Secreted Signaling -0.2750 0.0000000003994148189517573 Scatter Plot
Source GRN Target PARs PARs Secreted Signaling -0.2617 0.0000000028425604489843516 Scatter Plot
Source GRN Source SEMA4 SEMA4 Cell-Cell Contact -0.2432 0.000000036548943508911824 Scatter Plot
Source GRN Source MIF MIF Secreted Signaling -0.2347 0.00000010939284142952626 Scatter Plot
Source GRN Target SEMA7 SEMA7 Cell-Cell Contact -0.2148 0.0000012475753711351056 Scatter Plot
Source GRN Source GP1BA GP1BA Cell-Cell Contact -0.2035 0.000004480780559289843 Scatter Plot
Source GRN Target SPP1 SPP1 Secreted Signaling -0.1988 0.000007493369499542483 Scatter Plot
Source GRN Target PDGF PDGF Secreted Signaling -0.1963 0.000009828050096422704 Scatter Plot
Source GRN Source EPHB EPHB Cell-Cell Contact -0.1919 0.000015535797521969617 Scatter Plot
Source GRN Source CXCL CXCL Secreted Signaling -0.1803 0.00005033161115928396 Scatter Plot
Target GRN Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.1748 0.00008542547979945631 Scatter Plot
Source GRN Target TWEAK TWEAK Secreted Signaling -0.1586 0.0003707678664164 Scatter Plot
Source GRN Target FN1 FN1 ECM-Receptor -0.1524 0.0006287508549241 Scatter Plot
Target GRN Target PARs PARs Secreted Signaling -0.1510 0.0007032910795533 Scatter Plot
Target GRN Target BMP BMP Secreted Signaling -0.1429 0.0013530738162851 Scatter Plot
Target GRN Target THBS THBS ECM-Receptor -0.1365 0.002219242320831 Scatter Plot
Target GRN Target OSM OSM Secreted Signaling -0.1341 0.0026621546739631 Scatter Plot
Target GRN Target SPP1 SPP1 Secreted Signaling -0.1332 0.0028389698085211 Scatter Plot
Source GRN Target SELL SELL Cell-Cell Contact -0.1276 0.0042555543454204 Scatter Plot
Source GRN Target IL1 IL1 Secreted Signaling -0.1202 0.007123466076886 Scatter Plot
Target GRN Target NRG NRG Secreted Signaling -0.1202 0.0071494411986678 Scatter Plot
Source GRN Source IL1 IL1 Secreted Signaling -0.1161 0.0093656957617073 Scatter Plot
Target GRN Target TGFb TGFb Secreted Signaling -0.1099 0.0139494654564507 Scatter Plot
Target GRN Target MIF MIF Secreted Signaling -0.1098 0.014013110522277 Scatter Plot
Source GRN Target VWF VWF ECM-Receptor -0.1080 0.0156892743806145 Scatter Plot
Source GRN Source THY1 THY1 Cell-Cell Contact -0.1054 0.0183437540392507 Scatter Plot
Target GRN Target CD200 CD200 Cell-Cell Contact -0.1028 0.0214707080966146 Scatter Plot
Source GRN Target IGF IGF Secreted Signaling -0.0990 0.0268995829004711 Scatter Plot
Source GRN Source MHC-I MHC-I Cell-Cell Contact -0.0988 0.0272107796913709 Scatter Plot
Source GRN Target PECAM1 PECAM1 Cell-Cell Contact -0.0973 0.0296271071568478 Scatter Plot

Cells that are targets of GRN from HSCs*

Cells that are source of GRN to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.