Pathway: CADM

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Cell-Cell Contact

Details on the CADM pathway:

Specificity Index HSPC as target: 0.141
HSPC as source: 0.141

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the CADM pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target CADM Source NCAM NCAM Cell-Cell Contact 0.1016 0.0230412738507618 Scatter Plot
Target CADM Target VEGF VEGF Secreted Signaling 0.1071 0.0165425467095002 Scatter Plot
Source CADM Source SEMA6 SEMA6 Cell-Cell Contact 0.1076 0.0161142164470606 Scatter Plot
Target CADM Source SEMA6 SEMA6 Cell-Cell Contact 0.1076 0.0161142164470606 Scatter Plot
Target CADM Target MK MK Secreted Signaling 0.1134 0.0111337986274767 Scatter Plot
Target CADM Source VCAM VCAM Cell-Cell Contact 0.1143 0.0105655723988841 Scatter Plot
Target CADM Target GAS GAS Secreted Signaling 0.1173 0.0086298635631401 Scatter Plot
Source CADM Source ncWNT ncWNT Secreted Signaling 0.1267 0.0045499229298026 Scatter Plot
Target CADM Source ncWNT ncWNT Secreted Signaling 0.1267 0.0045499229298026 Scatter Plot
Source CADM Source GRN GRN Secreted Signaling 0.1305 0.0034637661875086 Scatter Plot
Target CADM Source GRN GRN Secreted Signaling 0.1305 0.0034637661875086 Scatter Plot
Target CADM Source MK MK Secreted Signaling 0.1312 0.0032824664805992 Scatter Plot
Target CADM Source THY1 THY1 Cell-Cell Contact 0.1371 0.0021211559822946 Scatter Plot
Target CADM Target EPHA EPHA Cell-Cell Contact 0.1445 0.0011931661768265 Scatter Plot
Target CADM Source CXCL CXCL Secreted Signaling 0.1459 0.0010702938221305 Scatter Plot
Target CADM Target GDF GDF Secreted Signaling 0.1478 0.0009168260435808 Scatter Plot
Target CADM Target PTN PTN Secreted Signaling 0.1505 0.0007362964695871 Scatter Plot
Target CADM Source AGRN AGRN ECM-Receptor 0.1540 0.0005474118196226 Scatter Plot
Source CADM Source AGRN AGRN ECM-Receptor 0.1540 0.0005474118196226 Scatter Plot
Target CADM Source PROS PROS Secreted Signaling 0.1641 0.0002281932805558 Scatter Plot
Target CADM Source IL16 IL16 Secreted Signaling 0.1645 0.0002197604136244 Scatter Plot
Target CADM Source CD86 CD86 Cell-Cell Contact 0.1672 0.0001721806251976 Scatter Plot
Target CADM Source GP1BA GP1BA Cell-Cell Contact 0.1750 0.000083725832781358 Scatter Plot
Target CADM Target SEMA3 SEMA3 Secreted Signaling 0.1814 0.00004501538827526434 Scatter Plot
Target CADM Source APELIN APELIN Secreted Signaling 0.1832 0.00003783169523518696 Scatter Plot
Source CADM Source APELIN APELIN Secreted Signaling 0.1832 0.00003783169523518696 Scatter Plot
Target CADM Target SPP1 SPP1 Secreted Signaling 0.1836 0.0000363776153848652 Scatter Plot
Target CADM Source IL2 IL2 Secreted Signaling 0.1852 0.00003074556336632607 Scatter Plot
Source CADM Source CCL CCL Secreted Signaling 0.1905 0.0000180086979149399 Scatter Plot
Source CADM Source EPHB EPHB Cell-Cell Contact 0.1946 0.000011731499526474069 Scatter Plot
Target CADM Source EPHB EPHB Cell-Cell Contact 0.1946 0.000011731499526474069 Scatter Plot
Target CADM Target COMPLEMENT COMPLEMENT Secreted Signaling 0.1947 0.00001165840350318076 Scatter Plot
Source CADM Source VEGF VEGF Secreted Signaling 0.1956 0.000010588672224453676 Scatter Plot
Target CADM Source VEGF VEGF Secreted Signaling 0.1956 0.000010588672224453676 Scatter Plot
Target CADM Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.1982 0.000008033495773788004 Scatter Plot
Target CADM Source CSF CSF Secreted Signaling 0.2068 0.00000311093888753488 Scatter Plot
Target CADM Source NT NT Secreted Signaling 0.2092 0.000002366506058434889 Scatter Plot
Source CADM Source LIGHT LIGHT Secreted Signaling 0.2118 0.0000017641257815032352 Scatter Plot
Target CADM Source LIGHT LIGHT Secreted Signaling 0.2118 0.0000017641257815032352 Scatter Plot
Target CADM Target CD200 CD200 Cell-Cell Contact 0.2122 0.000001685052732332151 Scatter Plot
Source CADM Source LAMININ LAMININ ECM-Receptor 0.2145 0.0000012899787570546415 Scatter Plot
Target CADM Source LAMININ LAMININ ECM-Receptor 0.2145 0.0000012899787570546415 Scatter Plot
Target CADM Target SEMA7 SEMA7 Cell-Cell Contact 0.2153 0.0000011770938712574758 Scatter Plot
Target CADM Source CD45 CD45 Cell-Cell Contact 0.2185 0.0000008039196750612445 Scatter Plot
Source CADM Source CD45 CD45 Cell-Cell Contact 0.2185 0.0000008039196750612445 Scatter Plot
Target CADM Source ICAM ICAM Cell-Cell Contact 0.2215 0.0000005653286331392954 Scatter Plot
Target CADM Target KIT KIT Secreted Signaling 0.2246 0.0000003887744554952382 Scatter Plot
Target CADM Source CCL CCL Secreted Signaling 0.2261 0.0000003242640738326143 Scatter Plot
Target CADM Source IGF IGF Secreted Signaling 0.2295 0.00000021254201862202114 Scatter Plot
Target CADM Target COLLAGEN COLLAGEN ECM-Receptor 0.2321 0.0000001524000089129561 Scatter Plot
Source CADM Source WNT WNT Secreted Signaling 0.2331 0.0000001348057305511477 Scatter Plot
Target CADM Source WNT WNT Secreted Signaling 0.2331 0.0000001348057305511477 Scatter Plot
Source CADM Source ANGPT ANGPT Secreted Signaling 0.2333 0.00000013078852137674676 Scatter Plot
Target CADM Source ANGPT ANGPT Secreted Signaling 0.2333 0.00000013078852137674676 Scatter Plot
Target CADM Source NOTCH NOTCH Cell-Cell Contact 0.2389 0.00000006382441857566373 Scatter Plot
Target CADM Target FN1 FN1 ECM-Receptor 0.2400 0.000000055229803165740425 Scatter Plot
Target CADM Source BST2 BST2 Cell-Cell Contact 0.2401 0.000000054912945975235284 Scatter Plot
Target CADM Source FLT3 FLT3 Secreted Signaling 0.2401 0.000000054658891690383576 Scatter Plot
Target CADM Target NCAM NCAM Cell-Cell Contact 0.2405 0.000000051847868070848654 Scatter Plot
Source CADM Source SEMA3 SEMA3 Secreted Signaling 0.2436 0.000000034530620168045445 Scatter Plot
Target CADM Source SEMA3 SEMA3 Secreted Signaling 0.2436 0.000000034530620168045445 Scatter Plot
Source CADM Source CDH CDH Cell-Cell Contact 0.2451 0.000000028239964042159584 Scatter Plot
Target CADM Target CDH CDH Cell-Cell Contact 0.2451 0.000000028239964042159584 Scatter Plot
Target CADM Source CDH CDH Cell-Cell Contact 0.2451 0.000000028239941021473564 Scatter Plot
Source CADM Source CD39 CD39 Cell-Cell Contact 0.2459 0.000000025519504867057746 Scatter Plot
Target CADM Source CD39 CD39 Cell-Cell Contact 0.2459 0.000000025519504867057746 Scatter Plot
Target CADM Target ANGPTL ANGPTL Secreted Signaling 0.2508 0.000000013102663353167884 Scatter Plot
Target CADM Target TENASCIN TENASCIN ECM-Receptor 0.2549 0.000000007452166053727397 Scatter Plot
Source CADM Source COLLAGEN COLLAGEN ECM-Receptor 0.2569 0.000000005623712329997454 Scatter Plot
Target CADM Source LCK LCK Cell-Cell Contact 0.2596 0.0000000038463133247535775 Scatter Plot
Source CADM Source LIFR LIFR Secreted Signaling 0.2601 0.0000000035683352520599194 Scatter Plot
Target CADM Source LIFR LIFR Secreted Signaling 0.2601 0.0000000035683352520599194 Scatter Plot
Target CADM Source IL7 IL7 Secreted Signaling 0.2603 0.000000003443643134857921 Scatter Plot
Target CADM Target IGF IGF Secreted Signaling 0.2622 0.0000000026490395336183597 Scatter Plot
Target CADM Source COLLAGEN COLLAGEN ECM-Receptor 0.2646 0.0000000018529931221867203 Scatter Plot
Target CADM Source PSAP PSAP Secreted Signaling 0.2647 0.000000001836662840899705 Scatter Plot
Source CADM Source PSAP PSAP Secreted Signaling 0.2647 0.000000001836662840899705 Scatter Plot
Target CADM Target ACTIVIN ACTIVIN Secreted Signaling 0.2687 0.0000000010210919086100531 Scatter Plot
Target CADM Target CD39 CD39 Cell-Cell Contact 0.2712 0.0000000006993480567428811 Scatter Plot
Target CADM Source RANKL RANKL Secreted Signaling 0.2718 0.0000000006433550783837602 Scatter Plot
Source CADM Source RANKL RANKL Secreted Signaling 0.2718 0.0000000006433550783837602 Scatter Plot
Target CADM Target VWF VWF ECM-Receptor 0.2793 0.00000000020632093133508029 Scatter Plot
Source CADM Source PDGF PDGF Secreted Signaling 0.2794 0.00000000020378048332710963 Scatter Plot
Target CADM Source PDGF PDGF Secreted Signaling 0.2794 0.00000000020378048332710963 Scatter Plot
Target CADM Target PERIOSTIN PERIOSTIN Secreted Signaling 0.2849 0.00000000008571792149077427 Scatter Plot
Target CADM Target SEMA6 SEMA6 Cell-Cell Contact 0.2866 0.0000000000651899721372209 Scatter Plot
Target CADM Source CD46 CD46 Cell-Cell Contact 0.2919 0.00000000002807099355457313 Scatter Plot
Source CADM Source CD46 CD46 Cell-Cell Contact 0.2919 0.00000000002807099355457313 Scatter Plot
Target CADM Target ncWNT ncWNT Secreted Signaling 0.2923 0.000000000026277236766056462 Scatter Plot
Target CADM Source MHC-II MHC-II Cell-Cell Contact 0.2960 0.00000000001435378957520965 Scatter Plot
Target CADM Source SEMA7 SEMA7 Cell-Cell Contact 0.2962 0.000000000013981241105147064 Scatter Plot
Target CADM Target BSP BSP ECM-Receptor 0.3046 0.000000000003407125865924579 Scatter Plot
Target CADM Source BMP BMP Secreted Signaling 0.3098 0.0000000000013764431019381202 Scatter Plot
Target CADM Source CX3C CX3C Secreted Signaling 0.3114 0.0000000000010502485604267876 Scatter Plot
Target CADM Target SLURP SLURP Secreted Signaling 0.3114 0.000000000001044407715617468 Scatter Plot
Target CADM Target WNT WNT Secreted Signaling 0.3122 0.00000000000091828814981181 Scatter Plot
Target CADM Target CSPG4 CSPG4 Cell-Cell Contact 0.3145 0.0000000000006059964090628643 Scatter Plot
Target CADM Source ESAM ESAM Cell-Cell Contact 0.3220 0.00000000000015897045906712025 Scatter Plot
Target CADM Source GAS GAS Secreted Signaling 0.3240 0.00000000000011004630795571013 Scatter Plot
Target CADM Source MHC-I MHC-I Cell-Cell Contact 0.3262 0.0000000000000735825957913848 Scatter Plot
Target CADM Target FGF FGF Secreted Signaling 0.3313 0.000000000000028162773501088646 Scatter Plot
Target CADM Target CD34 CD34 Cell-Cell Contact 0.3409 0.000000000000004530567278991148 Scatter Plot
Target CADM Target JAM JAM Cell-Cell Contact 0.3431 0.000000000000002937134516511857 Scatter Plot
Target CADM Source TWEAK TWEAK Secreted Signaling 0.3451 0.000000000000001985228696688703 Scatter Plot
Source CADM Source TWEAK TWEAK Secreted Signaling 0.3451 0.000000000000001985228696688703 Scatter Plot
Target CADM Source JAM JAM Cell-Cell Contact 0.3609 0.00000000000000007929429715822815 Scatter Plot
Target CADM Source CD52 CD52 Cell-Cell Contact -0.2485 0.000000017777339700395533 Scatter Plot
Target CADM Source MIF MIF Secreted Signaling -0.2223 0.0000005099607525468458 Scatter Plot
Target CADM Source TGFb TGFb Secreted Signaling -0.2007 0.000006131448419651228 Scatter Plot
Source CADM Source TGFb TGFb Secreted Signaling -0.2007 0.000006131448419651228 Scatter Plot
Target CADM Target CXCL CXCL Secreted Signaling -0.1915 0.000016249542237628716 Scatter Plot
Target CADM Source COMPLEMENT COMPLEMENT Secreted Signaling -0.1788 0.00005817854735270781 Scatter Plot
Target CADM Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.1742 0.00008981633605948725 Scatter Plot
Source CADM Source SEMA4 SEMA4 Cell-Cell Contact -0.1706 0.0001268062771219 Scatter Plot
Target CADM Source SEMA4 SEMA4 Cell-Cell Contact -0.1706 0.0001268062771219 Scatter Plot
Target CADM Source PARs PARs Secreted Signaling -0.1575 0.0004079935224575 Scatter Plot
Target CADM Source CLEC CLEC Cell-Cell Contact -0.1388 0.0018582070100908 Scatter Plot
Source CADM Source ANGPTL ANGPTL Secreted Signaling -0.1366 0.0022090518026766 Scatter Plot
Target CADM Source ANGPTL ANGPTL Secreted Signaling -0.1366 0.0022090518026766 Scatter Plot
Target CADM Source SELL SELL Cell-Cell Contact -0.1280 0.0041447203115756 Scatter Plot
Source CADM Source SELL SELL Cell-Cell Contact -0.1280 0.0041447203115756 Scatter Plot
Target CADM Target IL17 IL17 Secreted Signaling -0.1276 0.004263785488236 Scatter Plot
Target CADM Source SELPLG SELPLG Cell-Cell Contact -0.1224 0.0061175925925502 Scatter Plot
Target CADM Source THBS THBS ECM-Receptor -0.1112 0.012861631054813 Scatter Plot
Target CADM Source NKG2D NKG2D Cell-Cell Contact -0.1091 0.0146990552021456 Scatter Plot
Target CADM Source TNF TNF Secreted Signaling -0.1026 0.0216963008602489 Scatter Plot
Source CADM Source TNF TNF Secreted Signaling -0.1026 0.0216963008602489 Scatter Plot
Source CADM Source NCAM NCAM Cell-Cell Contact 0.1016 0.0230412738507618 Scatter Plot
Source CADM Target NOTCH NOTCH Cell-Cell Contact 0.1053 0.0184681921286179 Scatter Plot
Target CADM Target NOTCH NOTCH Cell-Cell Contact 0.1053 0.0184681921286179 Scatter Plot
Source CADM Target VEGF VEGF Secreted Signaling 0.1071 0.0165425467095002 Scatter Plot
Target CADM Target NODAL NODAL Secreted Signaling 0.1075 0.0161779094452663 Scatter Plot
Source CADM Target NODAL NODAL Secreted Signaling 0.1075 0.0161779094452663 Scatter Plot
Source CADM Target MK MK Secreted Signaling 0.1134 0.0111337986274767 Scatter Plot
Source CADM Source VCAM VCAM Cell-Cell Contact 0.1143 0.0105655723988841 Scatter Plot
Source CADM Target GAS GAS Secreted Signaling 0.1173 0.0086298635631401 Scatter Plot
Target CADM Target GALECTIN GALECTIN Secreted Signaling 0.1290 0.0038601299570474 Scatter Plot
Source CADM Target GALECTIN GALECTIN Secreted Signaling 0.1290 0.0038601299570474 Scatter Plot
Source CADM Source MK MK Secreted Signaling 0.1312 0.0032824664805992 Scatter Plot
Target CADM Target CD45 CD45 Cell-Cell Contact 0.1364 0.0022331119619392 Scatter Plot
Source CADM Target CD45 CD45 Cell-Cell Contact 0.1364 0.0022331119619392 Scatter Plot
Source CADM Source THY1 THY1 Cell-Cell Contact 0.1371 0.0021211559822946 Scatter Plot
Target CADM Target SELPLG SELPLG Cell-Cell Contact 0.1377 0.0020224030370152 Scatter Plot
Source CADM Target SELPLG SELPLG Cell-Cell Contact 0.1377 0.0020224030370152 Scatter Plot
Target CADM Target CD86 CD86 Cell-Cell Contact 0.1394 0.0017748205716474 Scatter Plot
Source CADM Target CD86 CD86 Cell-Cell Contact 0.1394 0.0017748205716474 Scatter Plot
Target CADM Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1404 0.0016436610687975 Scatter Plot
Source CADM Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1404 0.0016436610687975 Scatter Plot
Source CADM Target EPHA EPHA Cell-Cell Contact 0.1445 0.0011931661768265 Scatter Plot
Source CADM Source CXCL CXCL Secreted Signaling 0.1459 0.0010702938221305 Scatter Plot
Source CADM Target GDF GDF Secreted Signaling 0.1478 0.0009168260435808 Scatter Plot
Source CADM Target PTN PTN Secreted Signaling 0.1505 0.0007362964695871 Scatter Plot
Source CADM Target IL6 IL6 Secreted Signaling 0.1514 0.0006846605695999 Scatter Plot
Target CADM Target IL6 IL6 Secreted Signaling 0.1514 0.0006846605695999 Scatter Plot
Source CADM Source PROS PROS Secreted Signaling 0.1641 0.0002281932805558 Scatter Plot
Source CADM Source IL16 IL16 Secreted Signaling 0.1645 0.0002197604136244 Scatter Plot
Source CADM Source CD86 CD86 Cell-Cell Contact 0.1672 0.0001721806251976 Scatter Plot
Target CADM Target THY1 THY1 Cell-Cell Contact 0.1719 0.0001122011951406 Scatter Plot
Source CADM Target THY1 THY1 Cell-Cell Contact 0.1719 0.0001122011951406 Scatter Plot
Source CADM Source GP1BA GP1BA Cell-Cell Contact 0.1750 0.000083725832781358 Scatter Plot
Source CADM Target SEMA3 SEMA3 Secreted Signaling 0.1814 0.00004501538827526434 Scatter Plot
Target CADM Target EPHB EPHB Cell-Cell Contact 0.1824 0.00004075948182455446 Scatter Plot
Source CADM Target EPHB EPHB Cell-Cell Contact 0.1824 0.00004075948182455446 Scatter Plot
Source CADM Target SPP1 SPP1 Secreted Signaling 0.1836 0.0000363776153848652 Scatter Plot
Target CADM Target COLLAGEN COLLAGEN ECM-Receptor 0.1839 0.00003514883306146216 Scatter Plot
Source CADM Source IL2 IL2 Secreted Signaling 0.1852 0.00003074556336632607 Scatter Plot
Target CADM Target CD23 CD23 Cell-Cell Contact 0.1907 0.000017691432823954493 Scatter Plot
Source CADM Target CD23 CD23 Cell-Cell Contact 0.1907 0.000017691432823954493 Scatter Plot
Source CADM Target COMPLEMENT COMPLEMENT Secreted Signaling 0.1947 0.00001165840350318076 Scatter Plot
Target CADM Target AGT AGT Secreted Signaling 0.1969 0.000009153921242575252 Scatter Plot
Source CADM Target AGT AGT Secreted Signaling 0.1969 0.000009153921242575252 Scatter Plot
Source CADM Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.1982 0.000008033495773788004 Scatter Plot
Source CADM Target PARs PARs Secreted Signaling 0.2006 0.000006147719516151697 Scatter Plot
Target CADM Target PARs PARs Secreted Signaling 0.2006 0.000006147719516151697 Scatter Plot
Source CADM Source CSF CSF Secreted Signaling 0.2068 0.00000311093888753488 Scatter Plot
Source CADM Target COLLAGEN COLLAGEN ECM-Receptor 0.2081 0.000002676989471881857 Scatter Plot
Source CADM Source NT NT Secreted Signaling 0.2092 0.0000023665060584348933 Scatter Plot
Source CADM Target ANGPT ANGPT Secreted Signaling 0.2116 0.0000018151146157405492 Scatter Plot
Target CADM Target ANGPT ANGPT Secreted Signaling 0.2116 0.0000018151146157405492 Scatter Plot
Target CADM Target BAFF BAFF Secreted Signaling 0.2120 0.0000017333398029607545 Scatter Plot
Source CADM Target BAFF BAFF Secreted Signaling 0.2120 0.0000017333398029607545 Scatter Plot
Source CADM Target CD200 CD200 Cell-Cell Contact 0.2122 0.0000016791265697738784 Scatter Plot
Target CADM Target CD200 CD200 Cell-Cell Contact 0.2123 0.0000016657324974409624 Scatter Plot
Source CADM Target SEMA7 SEMA7 Cell-Cell Contact 0.2153 0.0000011770938712574758 Scatter Plot
Target CADM Target TGFb TGFb Secreted Signaling 0.2156 0.0000011415342011887984 Scatter Plot
Source CADM Target TGFb TGFb Secreted Signaling 0.2156 0.0000011415342011887984 Scatter Plot
Source CADM Source CD45 CD45 Cell-Cell Contact 0.2185 0.0000008039196750612445 Scatter Plot
Source CADM Target CD22 CD22 Cell-Cell Contact 0.2185 0.0000008039196750612445 Scatter Plot
Target CADM Target CD22 CD22 Cell-Cell Contact 0.2185 0.0000008039196750612445 Scatter Plot
Source CADM Source ICAM ICAM Cell-Cell Contact 0.2215 0.0000005653286331392954 Scatter Plot
Source CADM Target OSM OSM Secreted Signaling 0.2217 0.0000005484087108004105 Scatter Plot
Target CADM Target OSM OSM Secreted Signaling 0.2217 0.0000005484087108004105 Scatter Plot
Source CADM Target KIT KIT Secreted Signaling 0.2246 0.0000003887744554952382 Scatter Plot
Source CADM Source IGF IGF Secreted Signaling 0.2295 0.00000021254201862202114 Scatter Plot
Source CADM Source NOTCH NOTCH Cell-Cell Contact 0.2389 0.00000006382441857566373 Scatter Plot
Source CADM Target FN1 FN1 ECM-Receptor 0.2400 0.000000055229803165740425 Scatter Plot
Source CADM Source BST2 BST2 Cell-Cell Contact 0.2401 0.000000054912945975235284 Scatter Plot
Source CADM Source FLT3 FLT3 Secreted Signaling 0.2401 0.000000054658891690383576 Scatter Plot
Source CADM Target NCAM NCAM Cell-Cell Contact 0.2405 0.00000005184786807084829 Scatter Plot
Source CADM Target VISFATIN VISFATIN Secreted Signaling 0.2416 0.000000045018544557058386 Scatter Plot
Target CADM Target VISFATIN VISFATIN Secreted Signaling 0.2416 0.000000045018544557058386 Scatter Plot
Source CADM Source CCL CCL Secreted Signaling 0.2430 0.00000003741108783383237 Scatter Plot
Source CADM Target CDH CDH Cell-Cell Contact 0.2451 0.000000028239941021473564 Scatter Plot
Source CADM Source CDH CDH Cell-Cell Contact 0.2451 0.00000002823987195952392 Scatter Plot
Target CADM Target CDH CDH Cell-Cell Contact 0.2451 0.00000002823987195952392 Scatter Plot
Source CADM Source CD39 CD39 Cell-Cell Contact 0.2459 0.000000025519504867057746 Scatter Plot
Source CADM Target ANGPTL ANGPTL Secreted Signaling 0.2508 0.000000013102663353167884 Scatter Plot
Target CADM Target SEMA4 SEMA4 Cell-Cell Contact 0.2547 0.000000007657100950788436 Scatter Plot
Source CADM Target SEMA4 SEMA4 Cell-Cell Contact 0.2547 0.000000007657100950788436 Scatter Plot
Source CADM Target TENASCIN TENASCIN ECM-Receptor 0.2549 0.000000007452166053727397 Scatter Plot
Target CADM Target VTN VTN ECM-Receptor 0.2560 0.000000006338955021770191 Scatter Plot
Source CADM Target VTN VTN ECM-Receptor 0.2560 0.000000006338955021770191 Scatter Plot
Source CADM Source LCK LCK Cell-Cell Contact 0.2596 0.0000000038463133247535775 Scatter Plot
Source CADM Source IL7 IL7 Secreted Signaling 0.2603 0.000000003443643134857921 Scatter Plot
Source CADM Target IGF IGF Secreted Signaling 0.2622 0.0000000026490395336183407 Scatter Plot
Source CADM Source COLLAGEN COLLAGEN ECM-Receptor 0.2668 0.000000001350313041295281 Scatter Plot
Target CADM Target MIF MIF Secreted Signaling 0.2675 0.0000000012181839803755547 Scatter Plot
Source CADM Target MIF MIF Secreted Signaling 0.2675 0.0000000012181839803755547 Scatter Plot
Source CADM Target ACTIVIN ACTIVIN Secreted Signaling 0.2687 0.0000000010210919086100531 Scatter Plot
Target CADM Target LAMININ LAMININ ECM-Receptor 0.2695 0.000000000912826690524118 Scatter Plot
Source CADM Target LAMININ LAMININ ECM-Receptor 0.2695 0.000000000912826690524118 Scatter Plot
Source CADM Target CD39 CD39 Cell-Cell Contact 0.2712 0.0000000006993480567428811 Scatter Plot
Target CADM Target CD39 CD39 Cell-Cell Contact 0.2712 0.0000000006993480567428811 Scatter Plot
Source CADM Target THBS THBS ECM-Receptor 0.2735 0.0000000004967058448200184 Scatter Plot
Target CADM Target THBS THBS ECM-Receptor 0.2735 0.0000000004967058448200184 Scatter Plot
Source CADM Target VWF VWF ECM-Receptor 0.2793 0.00000000020632093133508029 Scatter Plot
Source CADM Target PERIOSTIN PERIOSTIN Secreted Signaling 0.2849 0.00000000008571792149077427 Scatter Plot
Source CADM Target SEMA6 SEMA6 Cell-Cell Contact 0.2866 0.0000000000651899721372209 Scatter Plot
Source CADM Target APP APP Cell-Cell Contact 0.2883 0.00000000005011258375686716 Scatter Plot
Target CADM Target APP APP Cell-Cell Contact 0.2883 0.00000000005011258375686716 Scatter Plot
Source CADM Source CD46 CD46 Cell-Cell Contact 0.2919 0.00000000002807099355457313 Scatter Plot
Target CADM Target NRG NRG Secreted Signaling 0.2920 0.00000000002769602941876746 Scatter Plot
Source CADM Target NRG NRG Secreted Signaling 0.2920 0.00000000002769602941876746 Scatter Plot
Source CADM Target ncWNT ncWNT Secreted Signaling 0.2923 0.000000000026277236766056462 Scatter Plot
Target CADM Target NPR2 NPR2 Secreted Signaling 0.2927 0.000000000024602989118740136 Scatter Plot
Source CADM Target NPR2 NPR2 Secreted Signaling 0.2927 0.000000000024602989118740136 Scatter Plot
Source CADM Source MHC-II MHC-II Cell-Cell Contact 0.2960 0.00000000001435378957520965 Scatter Plot
Source CADM Source SEMA7 SEMA7 Cell-Cell Contact 0.2962 0.000000000013981241105147064 Scatter Plot
Source CADM Target BSP BSP ECM-Receptor 0.3046 0.000000000003407125865924579 Scatter Plot
Source CADM Source BMP BMP Secreted Signaling 0.3098 0.0000000000013764431019381202 Scatter Plot
Source CADM Source CX3C CX3C Secreted Signaling 0.3114 0.0000000000010502485604267876 Scatter Plot
Source CADM Target SLURP SLURP Secreted Signaling 0.3114 0.000000000001044407715617468 Scatter Plot
Source CADM Target WNT WNT Secreted Signaling 0.3122 0.00000000000091828814981181 Scatter Plot
Source CADM Target CSPG4 CSPG4 Cell-Cell Contact 0.3145 0.0000000000006059964090628643 Scatter Plot
Target CADM Target CSPG4 CSPG4 Cell-Cell Contact 0.3145 0.0000000000006059964090628643 Scatter Plot
Target CADM Target DMP1 DMP1 ECM-Receptor 0.3149 0.000000000000565560840315424 Scatter Plot
Source CADM Target DMP1 DMP1 ECM-Receptor 0.3149 0.000000000000565560840315424 Scatter Plot
Source CADM Source ESAM ESAM Cell-Cell Contact 0.3220 0.00000000000015897045906712025 Scatter Plot
Source CADM Target ESAM ESAM Cell-Cell Contact 0.3220 0.00000000000015897045906712025 Scatter Plot
Target CADM Target ESAM ESAM Cell-Cell Contact 0.3220 0.00000000000015897045906712025 Scatter Plot
Source CADM Source GAS GAS Secreted Signaling 0.3240 0.00000000000011004630795571013 Scatter Plot
Source CADM Source MHC-I MHC-I Cell-Cell Contact 0.3262 0.0000000000000735825957913848 Scatter Plot
Source CADM Target FGF FGF Secreted Signaling 0.3313 0.000000000000028162773501088646 Scatter Plot
Target CADM Target CD34 CD34 Cell-Cell Contact 0.3409 0.000000000000004530567278991295 Scatter Plot
Source CADM Target CD34 CD34 Cell-Cell Contact 0.3409 0.000000000000004530567278991148 Scatter Plot
Source CADM Target JAM JAM Cell-Cell Contact 0.3431 0.000000000000002937134516511857 Scatter Plot
Source CADM Target SEMA5 SEMA5 Cell-Cell Contact 0.3452 0.0000000000000019208774449635198 Scatter Plot
Target CADM Target SEMA5 SEMA5 Cell-Cell Contact 0.3452 0.0000000000000019208774449635198 Scatter Plot
Source CADM Source JAM JAM Cell-Cell Contact 0.3609 0.00000000000000007929429715822815 Scatter Plot
Target CADM Target BMP BMP Secreted Signaling 0.3654 0.00000000000000003052727290929955 Scatter Plot
Source CADM Target BMP BMP Secreted Signaling 0.3654 0.000000000000000030527272909298895 Scatter Plot
Source CADM Source CD52 CD52 Cell-Cell Contact -0.2485 0.000000017777339700395533 Scatter Plot
Source CADM Source MIF MIF Secreted Signaling -0.2223 0.000000509960752546844 Scatter Plot
Source CADM Target CXCL CXCL Secreted Signaling -0.1890 0.00002095037798750669 Scatter Plot
Source CADM Source COMPLEMENT COMPLEMENT Secreted Signaling -0.1788 0.00005817854735270815 Scatter Plot
Target CADM Target CXCL CXCL Secreted Signaling -0.1750 0.00008354312291222369 Scatter Plot
Source CADM Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.1742 0.00008981633605948725 Scatter Plot
Target CADM Target ICAM ICAM Cell-Cell Contact -0.1686 0.0001526506519122 Scatter Plot
Source CADM Target ICAM ICAM Cell-Cell Contact -0.1686 0.0001526506519122 Scatter Plot
Target CADM Target VCAM VCAM Cell-Cell Contact -0.1598 0.0003328195371081 Scatter Plot
Source CADM Target VCAM VCAM Cell-Cell Contact -0.1598 0.0003328195371081 Scatter Plot
Source CADM Source PARs PARs Secreted Signaling -0.1575 0.0004079935224575 Scatter Plot
Source CADM Source CLEC CLEC Cell-Cell Contact -0.1388 0.0018582070100908 Scatter Plot
Source CADM Target CCL CCL Secreted Signaling -0.1314 0.0032551347520659 Scatter Plot
Target CADM Target CCL CCL Secreted Signaling -0.1314 0.0032551347520659 Scatter Plot
Source CADM Target IL17 IL17 Secreted Signaling -0.1276 0.004263785488236 Scatter Plot
Source CADM Source SELPLG SELPLG Cell-Cell Contact -0.1224 0.0061175925925501 Scatter Plot
Source CADM Target VEGF VEGF Secreted Signaling -0.1138 0.0108979744013326 Scatter Plot
Target CADM Target VEGF VEGF Secreted Signaling -0.1138 0.0108979744013326 Scatter Plot
Source CADM Source THBS THBS ECM-Receptor -0.1112 0.012861631054813 Scatter Plot
Source CADM Source NKG2D NKG2D Cell-Cell Contact -0.1091 0.0146990552021456 Scatter Plot
Source CADM Target CD52 CD52 Cell-Cell Contact -0.1065 0.017191650662854 Scatter Plot
Target CADM Target CD52 CD52 Cell-Cell Contact -0.1065 0.017191650662854 Scatter Plot
Source CADM Target IFN-II IFN-II Secreted Signaling -0.1038 0.0203101716344776 Scatter Plot
Target CADM Target IFN-II IFN-II Secreted Signaling -0.1038 0.0203101716344776 Scatter Plot
Target CADM Target GRN GRN Secreted Signaling -0.1036 0.0205410360714534 Scatter Plot
Source CADM Target GRN GRN Secreted Signaling -0.1036 0.0205410360714535 Scatter Plot

Cells that are targets of CADM from HSCs*

Cells that are source of CADM to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.