Pathway: EPHB

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Cell-Cell Contact

Details on the EPHB pathway:

Specificity Index HSPC as target: 0.449
HSPC as source: 0.289

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the EPHB pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target EPHB Source CD34 CD34 Cell-Cell Contact 0.1027 0.0216781141519552 Scatter Plot
Target EPHB Source FGF FGF Secreted Signaling 0.1091 0.0146156841978453 Scatter Plot
Source EPHB Source APELIN APELIN Secreted Signaling 0.1150 0.0100944978209937 Scatter Plot
Target EPHB Source IL6 IL6 Secreted Signaling 0.1173 0.0086822023403085 Scatter Plot
Target EPHB Source GP1BA GP1BA Cell-Cell Contact 0.1225 0.0061130909130682 Scatter Plot
Target EPHB Source PECAM1 PECAM1 Cell-Cell Contact 0.1225 0.0061065425875509 Scatter Plot
Target EPHB Source SEMA6 SEMA6 Cell-Cell Contact 0.1240 0.0055081743556942 Scatter Plot
Target EPHB Source CD1D2 CD1D2 Cell-Cell Contact 0.1281 0.0041067052353239 Scatter Plot
Target EPHB Target NCAM NCAM Cell-Cell Contact 0.1294 0.0037553469333857 Scatter Plot
Source EPHB Source ncWNT ncWNT Secreted Signaling 0.1298 0.0036492473465259 Scatter Plot
Target EPHB Source THBS THBS ECM-Receptor 0.1309 0.0033558690720302 Scatter Plot
Target EPHB Source WNT WNT Secreted Signaling 0.1316 0.0031938237051702 Scatter Plot
Target EPHB Source ICOS ICOS Cell-Cell Contact 0.1469 0.0009892411856201 Scatter Plot
Target EPHB Source GDF GDF Secreted Signaling 0.1488 0.0008438418435226 Scatter Plot
Source EPHB Source FGF FGF Secreted Signaling 0.1688 0.0001492291533241 Scatter Plot
Source EPHB Source SEMA3 SEMA3 Secreted Signaling 0.1804 0.00004980045605317754 Scatter Plot
Target EPHB Source SEMA3 SEMA3 Secreted Signaling 0.1815 0.00004459966427384086 Scatter Plot
Target EPHB Target CADM CADM Cell-Cell Contact 0.1824 0.00004075948182455446 Scatter Plot
Target EPHB Source CADM CADM Cell-Cell Contact 0.1824 0.00004075948182455446 Scatter Plot
Target EPHB Source PTN PTN Secreted Signaling 0.1883 0.000022474853192495927 Scatter Plot
Target EPHB Target CSPG4 CSPG4 Cell-Cell Contact 0.1903 0.00001839336288898054 Scatter Plot
Target EPHB Source THY1 THY1 Cell-Cell Contact 0.2047 0.000003920292586812863 Scatter Plot
Source EPHB Source CD39 CD39 Cell-Cell Contact 0.2051 0.000003777909973437978 Scatter Plot
Target EPHB Source VCAM VCAM Cell-Cell Contact 0.2060 0.0000034207464058178143 Scatter Plot
Target EPHB Source CD46 CD46 Cell-Cell Contact 0.2067 0.000003139486881587225 Scatter Plot
Target EPHB Target NOTCH NOTCH Cell-Cell Contact 0.2144 0.0000013035956415753178 Scatter Plot
Target EPHB Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2213 0.0000005757466368367458 Scatter Plot
Target EPHB Source CCL CCL Secreted Signaling 0.2235 0.00000044382618230044914 Scatter Plot
Source EPHB Source LAMININ LAMININ ECM-Receptor 0.2238 0.0000004253207792064491 Scatter Plot
Target EPHB Source APELIN APELIN Secreted Signaling 0.2265 0.000000308621913785613 Scatter Plot
Source EPHB Source LIGHT LIGHT Secreted Signaling 0.2288 0.00000023200570301157566 Scatter Plot
Target EPHB Source ANGPTL ANGPTL Secreted Signaling 0.2288 0.0000002314752208832265 Scatter Plot
Target EPHB Target ANGPTL ANGPTL Secreted Signaling 0.2334 0.00000012937023559369694 Scatter Plot
Target EPHB Source VEGF VEGF Secreted Signaling 0.2355 0.00000009927525985278247 Scatter Plot
Target EPHB Source CD39 CD39 Cell-Cell Contact 0.2359 0.00000009446848416067948 Scatter Plot
Target EPHB Source CXCL CXCL Secreted Signaling 0.2386 0.00000006653463679142069 Scatter Plot
Target EPHB Target GDF GDF Secreted Signaling 0.2466 0.000000023028633887396598 Scatter Plot
Target EPHB Source IL16 IL16 Secreted Signaling 0.2480 0.00000001908684350818539 Scatter Plot
Source EPHB Source RANKL RANKL Secreted Signaling 0.2518 0.00000001144254722774058 Scatter Plot
Target EPHB Source CD45 CD45 Cell-Cell Contact 0.2602 0.0000000035159288862190998 Scatter Plot
Target EPHB Source IL2 IL2 Secreted Signaling 0.2629 0.000000002369714221423275 Scatter Plot
Target EPHB Target SEMA5 SEMA5 Cell-Cell Contact 0.2656 0.0000000015996301180989507 Scatter Plot
Target EPHB Source RANKL RANKL Secreted Signaling 0.2721 0.0000000006188272310460185 Scatter Plot
Target EPHB Source NOTCH NOTCH Cell-Cell Contact 0.2742 0.0000000004514523000790579 Scatter Plot
Target EPHB Source LCK LCK Cell-Cell Contact 0.2797 0.00000000019309489559553782 Scatter Plot
Source EPHB Source VEGF VEGF Secreted Signaling 0.2810 0.00000000015721591273343455 Scatter Plot
Target EPHB Source LIFR LIFR Secreted Signaling 0.2829 0.0000000001180895464962729 Scatter Plot
Target EPHB Source NT NT Secreted Signaling 0.2885 0.000000000048458418795406755 Scatter Plot
Target EPHB Source CSF CSF Secreted Signaling 0.2911 0.00000000003213332000286283 Scatter Plot
Target EPHB Source ICAM ICAM Cell-Cell Contact 0.2915 0.00000000002982544528954202 Scatter Plot
Target EPHB Target SEMA6 SEMA6 Cell-Cell Contact 0.2926 0.000000000025005235376886908 Scatter Plot
Target EPHB Source LIGHT LIGHT Secreted Signaling 0.2948 0.000000000017336444672151777 Scatter Plot
Target EPHB Source IGF IGF Secreted Signaling 0.3001 0.000000000007254813206848706 Scatter Plot
Target EPHB Target THBS THBS ECM-Receptor 0.3007 0.0000000000066015878310676476 Scatter Plot
Target EPHB Source CD86 CD86 Cell-Cell Contact 0.3010 0.0000000000062440723239483895 Scatter Plot
Target EPHB Target VWF VWF ECM-Receptor 0.3016 0.000000000005605995666383797 Scatter Plot
Target EPHB Source MK MK Secreted Signaling 0.3069 0.000000000002285553555047778 Scatter Plot
Target EPHB Source PROS PROS Secreted Signaling 0.3130 0.0000000000007901926233179962 Scatter Plot
Target EPHB Target BSP BSP ECM-Receptor 0.3292 0.00000000000004211268283492448 Scatter Plot
Target EPHB Target ACTIVIN ACTIVIN Secreted Signaling 0.3417 0.0000000000000038208496050911945 Scatter Plot
Source EPHB Source MK MK Secreted Signaling 0.3420 0.000000000000003654152256009601 Scatter Plot
Target EPHB Source LAMININ LAMININ ECM-Receptor 0.3464 0.0000000000000015359316209661493 Scatter Plot
Target EPHB Source CX3C CX3C Secreted Signaling 0.3504 0.0000000000000006811505836339223 Scatter Plot
Target EPHB Source PDGF PDGF Secreted Signaling 0.3529 0.0000000000000004092431160808192 Scatter Plot
Target EPHB Target KIT KIT Secreted Signaling 0.3542 0.00000000000000031325945739980987 Scatter Plot
Target EPHB Source FLT3 FLT3 Secreted Signaling 0.3752 0.000000000000000003674233473349622 Scatter Plot
Target EPHB Source IL7 IL7 Secreted Signaling 0.3764 0.000000000000000002823685777473535 Scatter Plot
Target EPHB Target CD200 CD200 Cell-Cell Contact 0.3774 0.0000000000000000022451666357659712 Scatter Plot
Target EPHB Source PSAP PSAP Secreted Signaling 0.3835 0.0000000000000000005758824970213266 Scatter Plot
Source EPHB Source PDGF PDGF Secreted Signaling 0.3936 0.00000000000000000005610067342018081 Scatter Plot
Target EPHB Source TWEAK TWEAK Secreted Signaling 0.4016 0.00000000000000000000844383264437901 Scatter Plot
Target EPHB Source BST2 BST2 Cell-Cell Contact 0.4026 0.000000000000000000006590154306398788 Scatter Plot
Target EPHB Target CD39 CD39 Cell-Cell Contact 0.4028 0.000000000000000000006323646266280386 Scatter Plot
Target EPHB Source COLLAGEN COLLAGEN ECM-Receptor 0.4050 0.000000000000000000003641102873830726 Scatter Plot
Target EPHB Target SLURP SLURP Secreted Signaling 0.4056 0.0000000000000000000031487597303105093 Scatter Plot
Source EPHB Source LIFR LIFR Secreted Signaling 0.4194 0.00000000000000000000010161839172687687 Scatter Plot
Target EPHB Source SEMA7 SEMA7 Cell-Cell Contact 0.4307 0.0000000000000000000000053424948300218355 Scatter Plot
Target EPHB Source BMP BMP Secreted Signaling 0.4338 0.000000000000000000000002282455495068106 Scatter Plot
Source EPHB Source TWEAK TWEAK Secreted Signaling 0.4353 0.0000000000000000000000015595897150446602 Scatter Plot
Target EPHB Source ESAM ESAM Cell-Cell Contact 0.4360 0.0000000000000000000000012654583818060288 Scatter Plot
Source EPHB Source COLLAGEN COLLAGEN ECM-Receptor 0.4449 0.00000000000000000000000011120178857713768 Scatter Plot
Target EPHB Source GAS GAS Secreted Signaling 0.4612 0.0000000000000000000000000010469812187440275 Scatter Plot
Target EPHB Source CDH CDH Cell-Cell Contact 0.4702 0.00000000000000000000000000007104989766469551 Scatter Plot
Target EPHB Target CDH CDH Cell-Cell Contact 0.4702 0.00000000000000000000000000007104989766469551 Scatter Plot
Target EPHB Target ESAM ESAM Cell-Cell Contact 0.4801 0.000000000000000000000000000003420324418411033 Scatter Plot
Target EPHB Source MHC-I MHC-I Cell-Cell Contact 0.4842 0.0000000000000000000000000000009216852387290182 Scatter Plot
Target EPHB Source JAM JAM Cell-Cell Contact 0.4887 0.00000000000000000000000000000022286426045235577 Scatter Plot
Target EPHB Source MHC-II MHC-II Cell-Cell Contact 0.5112 0.00000000000000000000000000000000011790817773627731 Scatter Plot
Target EPHB Source ANGPT ANGPT Secreted Signaling 0.5160 0.00000000000000000000000000000000002232281712578541 Scatter Plot
Source EPHB Source ESAM ESAM Cell-Cell Contact 0.5528 0.000000000000000000000000000000000000000022825056817345148 Scatter Plot
Source EPHB Source ANGPT ANGPT Secreted Signaling 0.5716 0.000000000000000000000000000000000000000000009832055521141569 Scatter Plot
Source EPHB Source SEMA4 SEMA4 Cell-Cell Contact -0.3971 0.000000000000000000024621980682149934 Scatter Plot
Source EPHB Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.3821 0.0000000000000000007872970282019454 Scatter Plot
Target EPHB Source CD52 CD52 Cell-Cell Contact -0.3534 0.00000000000000036979037089999486 Scatter Plot
Target EPHB Source SELL SELL Cell-Cell Contact -0.3070 0.000000000002237581574664336 Scatter Plot
Target EPHB Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.2954 0.00000000001573811051920239 Scatter Plot
Target EPHB Source PARs PARs Secreted Signaling -0.2919 0.000000000028207618596991425 Scatter Plot
Target EPHB Target ICAM ICAM Cell-Cell Contact -0.2798 0.00000000018964115013065595 Scatter Plot
Target EPHB Source COMPLEMENT COMPLEMENT Secreted Signaling -0.2798 0.00000000019070566113809067 Scatter Plot
Target EPHB Source SEMA4 SEMA4 Cell-Cell Contact -0.2696 0.0000000008884751083053356 Scatter Plot
Target EPHB Source VISTA VISTA Cell-Cell Contact -0.2583 0.00000000461127720419189 Scatter Plot
Target EPHB Source TGFb TGFb Secreted Signaling -0.2319 0.0000001578690689816667 Scatter Plot
Source EPHB Source GRN GRN Secreted Signaling -0.1919 0.000015535797521969617 Scatter Plot
Target EPHB Source SPP1 SPP1 Secreted Signaling -0.1873 0.00002487038635369979 Scatter Plot
Target EPHB Target CXCL CXCL Secreted Signaling -0.1858 0.00002904604164782696 Scatter Plot
Target EPHB Source CLEC CLEC Cell-Cell Contact -0.1832 0.00003751531351485194 Scatter Plot
Target EPHB Source MIF MIF Secreted Signaling -0.1813 0.000045295475296962425 Scatter Plot
Target EPHB Source NCAM NCAM Cell-Cell Contact -0.1729 0.0001016952672527 Scatter Plot
Target EPHB Source ANGPTL ANGPTL Secreted Signaling -0.1720 0.0001112691769025 Scatter Plot
Source EPHB Source TGFb TGFb Secreted Signaling -0.1701 0.0001318215997394 Scatter Plot
Target EPHB Source CCL CCL Secreted Signaling -0.1473 0.0009570895409292 Scatter Plot
Target EPHB Source NKG2D NKG2D Cell-Cell Contact -0.1400 0.0016945777176626 Scatter Plot
Target EPHB Target COLLAGEN COLLAGEN ECM-Receptor -0.1382 0.0019461974546226 Scatter Plot
Target EPHB Source ANNEXIN ANNEXIN Secreted Signaling -0.1354 0.0024203621457534 Scatter Plot
Target EPHB Target IL17 IL17 Secreted Signaling -0.1323 0.0030285084951658 Scatter Plot
Source EPHB Source ANGPTL ANGPTL Secreted Signaling -0.1183 0.0080857313235162 Scatter Plot
Target EPHB Source APP APP Cell-Cell Contact -0.1147 0.0102917706568619 Scatter Plot
Target EPHB Source VISFATIN VISFATIN Secreted Signaling -0.1138 0.0108458149578069 Scatter Plot
Target EPHB Source LAIR1 LAIR1 Cell-Cell Contact -0.1118 0.0123412059026803 Scatter Plot
Target EPHB Source TNF TNF Secreted Signaling -0.1052 0.0186067560288661 Scatter Plot
Source EPHB Source OSM OSM Secreted Signaling 0.1008 0.024132822352478 Scatter Plot
Source EPHB Target SEMA3 SEMA3 Secreted Signaling 0.1010 0.0238440345671995 Scatter Plot
Target EPHB Target SELL SELL Cell-Cell Contact 0.1106 0.013360246962646 Scatter Plot
Source EPHB Target IL1 IL1 Secreted Signaling 0.1106 0.0133221319968779 Scatter Plot
Target EPHB Target GALECTIN GALECTIN Secreted Signaling 0.1108 0.0131868672458755 Scatter Plot
Source EPHB Target IL6 IL6 Secreted Signaling 0.1124 0.0118740719873742 Scatter Plot
Target EPHB Target THY1 THY1 Cell-Cell Contact 0.1154 0.0098170877492523 Scatter Plot
Source EPHB Source PTN PTN Secreted Signaling 0.1159 0.0095201839735997 Scatter Plot
Source EPHB Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1167 0.008999450377356 Scatter Plot
Target EPHB Target PECAM1 PECAM1 Cell-Cell Contact 0.1225 0.0061065425875509 Scatter Plot
Target EPHB Target CD23 CD23 Cell-Cell Contact 0.1305 0.0034593206102411 Scatter Plot
Source EPHB Target VEGF VEGF Secreted Signaling 0.1373 0.0020908145723806 Scatter Plot
Target EPHB Target IL1 IL1 Secreted Signaling 0.1401 0.0016848952936977 Scatter Plot
Target EPHB Target TWEAK TWEAK Secreted Signaling 0.1435 0.0012955681088893 Scatter Plot
Source EPHB Source NT NT Secreted Signaling 0.1453 0.0011246887502854 Scatter Plot
Source EPHB Target OSM OSM Secreted Signaling 0.1528 0.0006076669317329 Scatter Plot
Target EPHB Target VEGF VEGF Secreted Signaling 0.1591 0.000355878529364 Scatter Plot
Source EPHB Target NOTCH NOTCH Cell-Cell Contact 0.1644 0.0002219136743756 Scatter Plot
Source EPHB Source GDF GDF Secreted Signaling 0.1655 0.0002020092774594 Scatter Plot
Target EPHB Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1681 0.0001591881425099 Scatter Plot
Target EPHB Target COLLAGEN COLLAGEN ECM-Receptor 0.1684 0.0001550857279328 Scatter Plot
Source EPHB Source IL16 IL16 Secreted Signaling 0.1760 0.00007626701567562626 Scatter Plot
Source EPHB Source THBS THBS ECM-Receptor 0.1776 0.00006522676968150278 Scatter Plot
Source EPHB Target EPHA EPHA Cell-Cell Contact 0.1850 0.00003137886032148592 Scatter Plot
Source EPHB Source CADM CADM Cell-Cell Contact 0.1946 0.000011731499526474069 Scatter Plot
Source EPHB Target CADM CADM Cell-Cell Contact 0.1946 0.000011731499526474069 Scatter Plot
Source EPHB Target RANKL RANKL Secreted Signaling 0.1981 0.000008104277326766343 Scatter Plot
Target EPHB Target SEMA3 SEMA3 Secreted Signaling 0.1981 0.00000810231379692292 Scatter Plot
Target EPHB Target FN1 FN1 ECM-Receptor 0.2018 0.000005416160657664766 Scatter Plot
Source EPHB Target COLLAGEN COLLAGEN ECM-Receptor 0.2066 0.0000031980138816073065 Scatter Plot
Source EPHB Source GALECTIN GALECTIN Secreted Signaling 0.2069 0.0000030654060519863787 Scatter Plot
Target EPHB Target SPP1 SPP1 Secreted Signaling 0.2087 0.000002526085964446026 Scatter Plot
Source EPHB Target AGT AGT Secreted Signaling 0.2151 0.0000011999369241868096 Scatter Plot
Target EPHB Target RANKL RANKL Secreted Signaling 0.2166 0.000001013959906128466 Scatter Plot
Source EPHB Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2178 0.0000008801016699573297 Scatter Plot
Source EPHB Target ANGPTL ANGPTL Secreted Signaling 0.2197 0.0000007024520913267214 Scatter Plot
Target EPHB Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.2227 0.0000004907599978172376 Scatter Plot
Source EPHB Target PTN PTN Secreted Signaling 0.2246 0.0000003903799430238015 Scatter Plot
Source EPHB Source THY1 THY1 Cell-Cell Contact 0.2263 0.00000031647473395555533 Scatter Plot
Source EPHB Source NOTCH NOTCH Cell-Cell Contact 0.2269 0.0000002914883351872114 Scatter Plot
Source EPHB Source CSF CSF Secreted Signaling 0.2298 0.00000020459729342335323 Scatter Plot
Source EPHB Source CD46 CD46 Cell-Cell Contact 0.2310 0.0000001760037774428173 Scatter Plot
Source EPHB Target NODAL NODAL Secreted Signaling 0.2337 0.00000012526491363171088 Scatter Plot
Target EPHB Target OSM OSM Secreted Signaling 0.2410 0.000000048750805145752055 Scatter Plot
Source EPHB Source ICAM ICAM Cell-Cell Contact 0.2418 0.000000043781360279796994 Scatter Plot
Source EPHB Target GDF GDF Secreted Signaling 0.2427 0.000000039058468517739315 Scatter Plot
Source EPHB Source CCL CCL Secreted Signaling 0.2433 0.000000035878937964477006 Scatter Plot
Target EPHB Target AGT AGT Secreted Signaling 0.2445 0.00000003055981607640706 Scatter Plot
Source EPHB Target PERIOSTIN PERIOSTIN Secreted Signaling 0.2545 0.000000007824722738941557 Scatter Plot
Target EPHB Target SEMA7 SEMA7 Cell-Cell Contact 0.2555 0.0000000068476367146343805 Scatter Plot
Target EPHB Target CD22 CD22 Cell-Cell Contact 0.2602 0.000000003515928886219151 Scatter Plot
Source EPHB Target CSPG4 CSPG4 Cell-Cell Contact 0.2614 0.0000000029577531734243403 Scatter Plot
Source EPHB Source CD1D2 CD1D2 Cell-Cell Contact 0.2654 0.0000000016560450522544623 Scatter Plot
Target EPHB Target NODAL NODAL Secreted Signaling 0.2659 0.000000001544089578836815 Scatter Plot
Source EPHB Target SEMA6 SEMA6 Cell-Cell Contact 0.2662 0.000000001483780850665266 Scatter Plot
Source EPHB Target SPP1 SPP1 Secreted Signaling 0.2681 0.0000000011070235482166934 Scatter Plot
Target EPHB Target IL6 IL6 Secreted Signaling 0.2732 0.0000000005190826870574022 Scatter Plot
Target EPHB Target MK MK Secreted Signaling 0.2741 0.0000000004576121435638044 Scatter Plot
Source EPHB Source LCK LCK Cell-Cell Contact 0.2743 0.00000000044482185504813324 Scatter Plot
Source EPHB Source PSAP PSAP Secreted Signaling 0.2758 0.00000000034964681654773 Scatter Plot
Source EPHB Source IL2 IL2 Secreted Signaling 0.2760 0.00000000033985430916583063 Scatter Plot
Source EPHB Target ACTIVIN ACTIVIN Secreted Signaling 0.2794 0.00000000020143569552871814 Scatter Plot
Source EPHB Target BSP BSP ECM-Receptor 0.2801 0.00000000018261680908390504 Scatter Plot
Target EPHB Target PTN PTN Secreted Signaling 0.2801 0.0000000001821883055972175 Scatter Plot
Source EPHB Source GP1BA GP1BA Cell-Cell Contact 0.2856 0.00000000007636821246971847 Scatter Plot
Source EPHB Target SEMA5 SEMA5 Cell-Cell Contact 0.2868 0.00000000006374345006071972 Scatter Plot
Source EPHB Target NRG NRG Secreted Signaling 0.2902 0.00000000003673356252323349 Scatter Plot
Source EPHB Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.2907 0.00000000003390240202700535 Scatter Plot
Source EPHB Target DMP1 DMP1 ECM-Receptor 0.2955 0.000000000015690785378788786 Scatter Plot
Target EPHB Target VTN VTN ECM-Receptor 0.2984 0.000000000009605106691145958 Scatter Plot
Source EPHB Target THBS THBS ECM-Receptor 0.2987 0.000000000009107086811447987 Scatter Plot
Target EPHB Target LAMININ LAMININ ECM-Receptor 0.3016 0.000000000005644055726720981 Scatter Plot
Source EPHB Source CD45 CD45 Cell-Cell Contact 0.3034 0.000000000004194865150918194 Scatter Plot
Source EPHB Target CD22 CD22 Cell-Cell Contact 0.3034 0.000000000004194865150918194 Scatter Plot
Source EPHB Source IGF IGF Secreted Signaling 0.3035 0.000000000004085449688109805 Scatter Plot
Target EPHB Target NRG NRG Secreted Signaling 0.3095 0.0000000000014707445691234372 Scatter Plot
Target EPHB Target VISFATIN VISFATIN Secreted Signaling 0.3166 0.00000000000041656049184291513 Scatter Plot
Source EPHB Target VTN VTN ECM-Receptor 0.3167 0.0000000000004078657935767112 Scatter Plot
Target EPHB Target DMP1 DMP1 ECM-Receptor 0.3200 0.0000000000002292652647474276 Scatter Plot
Source EPHB Target FN1 FN1 ECM-Receptor 0.3201 0.00000000000022414366199473162 Scatter Plot
Target EPHB Target BMP BMP Secreted Signaling 0.3216 0.0000000000001701371197642313 Scatter Plot
Target EPHB Target PERIOSTIN PERIOSTIN Secreted Signaling 0.3239 0.00000000000011246170373305469 Scatter Plot
Source EPHB Target BMP BMP Secreted Signaling 0.3245 0.00000000000010040461780386733 Scatter Plot
Target EPHB Target ANGPT ANGPT Secreted Signaling 0.3258 0.00000000000007910320159149988 Scatter Plot
Source EPHB Source CD86 CD86 Cell-Cell Contact 0.3287 0.000000000000046207436028833277 Scatter Plot
Source EPHB Target SEMA4 SEMA4 Cell-Cell Contact 0.3314 0.0000000000000275412804246546 Scatter Plot
Source EPHB Source CX3C CX3C Secreted Signaling 0.3339 0.00000000000001743184821594757 Scatter Plot
Source EPHB Target MK MK Secreted Signaling 0.3365 0.000000000000010462837607778448 Scatter Plot
Source EPHB Source VCAM VCAM Cell-Cell Contact 0.3379 0.000000000000007994960124894671 Scatter Plot
Source EPHB Target BAFF BAFF Secreted Signaling 0.3456 0.0000000000000018003439160702492 Scatter Plot
Source EPHB Target VISFATIN VISFATIN Secreted Signaling 0.3464 0.0000000000000015220582641866097 Scatter Plot
Target EPHB Target IGF IGF Secreted Signaling 0.3471 0.0000000000000013310301412951562 Scatter Plot
Target EPHB Target FGF FGF Secreted Signaling 0.3506 0.00000000000000065309207868474 Scatter Plot
Source EPHB Target APP APP Cell-Cell Contact 0.3509 0.000000000000000614086823052753 Scatter Plot
Source EPHB Target MIF MIF Secreted Signaling 0.3541 0.00000000000000032412407042053473 Scatter Plot
Target EPHB Target NPR2 NPR2 Secreted Signaling 0.3572 0.00000000000000017190183629337262 Scatter Plot
Source EPHB Target NPR2 NPR2 Secreted Signaling 0.3576 0.00000000000000015808407387795834 Scatter Plot
Source EPHB Source BST2 BST2 Cell-Cell Contact 0.3595 0.00000000000000010493747792276903 Scatter Plot
Source EPHB Source CXCL CXCL Secreted Signaling 0.3639 0.00000000000000004158174440488245 Scatter Plot
Target EPHB Target ESAM ESAM Cell-Cell Contact 0.3659 0.000000000000000027395540562048235 Scatter Plot
Target EPHB Target SEMA4 SEMA4 Cell-Cell Contact 0.3664 0.000000000000000024688760738479677 Scatter Plot
Source EPHB Target CD200 CD200 Cell-Cell Contact 0.3688 0.0000000000000000147212503861115 Scatter Plot
Target EPHB Target BAFF BAFF Secreted Signaling 0.3695 0.000000000000000012694501791994266 Scatter Plot
Source EPHB Target TGFb TGFb Secreted Signaling 0.3780 0.0000000000000000019839507811682258 Scatter Plot
Source EPHB Target LAMININ LAMININ ECM-Receptor 0.3807 0.000000000000000001084757302615531 Scatter Plot
Source EPHB Target CDH CDH Cell-Cell Contact 0.3825 0.0000000000000000007124909063213821 Scatter Plot
Source EPHB Source CDH CDH Cell-Cell Contact 0.3825 0.0000000000000000007124909063213821 Scatter Plot
Target EPHB Target PARs PARs Secreted Signaling 0.3830 0.0000000000000000006472212587542506 Scatter Plot
Source EPHB Source PROS PROS Secreted Signaling 0.3913 0.00000000000000000009552772394910706 Scatter Plot
Source EPHB Target JAM JAM Cell-Cell Contact 0.3932 0.00000000000000000006088452625049321 Scatter Plot
Target EPHB Target TENASCIN TENASCIN ECM-Receptor 0.3964 0.00000000000000000002904772090426115 Scatter Plot
Source EPHB Target ANGPT ANGPT Secreted Signaling 0.3994 0.00000000000000000001428299125772678 Scatter Plot
Source EPHB Target VWF VWF ECM-Receptor 0.4075 0.0000000000000000000020066038402966323 Scatter Plot
Target EPHB Target APP APP Cell-Cell Contact 0.4075 0.0000000000000000000020056176426221672 Scatter Plot
Source EPHB Source ESAM ESAM Cell-Cell Contact 0.4115 0.0000000000000000000007427699520252759 Scatter Plot
Source EPHB Source IL7 IL7 Secreted Signaling 0.4121 0.00000000000000000000062807835459812235 Scatter Plot
Source EPHB Target CD34 CD34 Cell-Cell Contact 0.4147 0.0000000000000000000003325470427796369 Scatter Plot
Source EPHB Target SEMA7 SEMA7 Cell-Cell Contact 0.4192 0.00000000000000000000010678312054534626 Scatter Plot
Source EPHB Target SLURP SLURP Secreted Signaling 0.4202 0.00000000000000000000008215713334953438 Scatter Plot
Target EPHB Target JAM JAM Cell-Cell Contact 0.4222 0.000000000000000000000048655378700695893 Scatter Plot
Target EPHB Target CD34 CD34 Cell-Cell Contact 0.4248 0.000000000000000000000024823190015477606 Scatter Plot
Source EPHB Target IGF IGF Secreted Signaling 0.4257 0.00000000000000000000001947480105924534 Scatter Plot
Source EPHB Target FGF FGF Secreted Signaling 0.4260 0.000000000000000000000018265295292713816 Scatter Plot
Target EPHB Target TGFb TGFb Secreted Signaling 0.4268 0.00000000000000000000001495757732735399 Scatter Plot
Source EPHB Source FLT3 FLT3 Secreted Signaling 0.4289 0.000000000000000000000008506085219764805 Scatter Plot
Source EPHB Source GAS GAS Secreted Signaling 0.4325 0.000000000000000000000003255743984355109 Scatter Plot
Source EPHB Source BMP BMP Secreted Signaling 0.4366 0.0000000000000000000000010833870548269887 Scatter Plot
Source EPHB Source SEMA7 SEMA7 Cell-Cell Contact 0.4410 0.0000000000000000000000003235924253639198 Scatter Plot
Source EPHB Target TENASCIN TENASCIN ECM-Receptor 0.4504 0.000000000000000000000000023806274430604382 Scatter Plot
Source EPHB Target CD39 CD39 Cell-Cell Contact 0.4599 0.000000000000000000000000001549028297193725 Scatter Plot
Target EPHB Target MIF MIF Secreted Signaling 0.4659 0.00000000000000000000000000026171675532707927 Scatter Plot
Source EPHB Target ncWNT ncWNT Secreted Signaling 0.4689 0.0000000000000000000000000001049284207007192 Scatter Plot
Source EPHB Target WNT WNT Secreted Signaling 0.4711 0.00000000000000000000000000005492540968473462 Scatter Plot
Source EPHB Target KIT KIT Secreted Signaling 0.4728 0.000000000000000000000000000032691230428368577 Scatter Plot
Target EPHB Target WNT WNT Secreted Signaling 0.4778 0.000000000000000000000000000006846394386399874 Scatter Plot
Target EPHB Target ncWNT ncWNT Secreted Signaling 0.4783 0.0000000000000000000000000000059509772520649225 Scatter Plot
Source EPHB Source MHC-II MHC-II Cell-Cell Contact 0.4945 0.0000000000000000000000000000000330109742095095 Scatter Plot
Source EPHB Source JAM JAM Cell-Cell Contact 0.4963 0.000000000000000000000000000000018597024344187806 Scatter Plot
Source EPHB Target ESAM ESAM Cell-Cell Contact 0.4993 0.000000000000000000000000000000006797365628271267 Scatter Plot
Source EPHB Target PARs PARs Secreted Signaling 0.5072 0.0000000000000000000000000000000004774391644910194 Scatter Plot
Source EPHB Source MHC-I MHC-I Cell-Cell Contact 0.5702 0.000000000000000000000000000000000000000000018277579963484116 Scatter Plot
Source EPHB Source CD52 CD52 Cell-Cell Contact -0.4754 0.000000000000000000000000000014715607014959472 Scatter Plot
Source EPHB Source COMPLEMENT COMPLEMENT Secreted Signaling -0.4742 0.000000000000000000000000000020696777868257256 Scatter Plot
Source EPHB Source SELL SELL Cell-Cell Contact -0.4487 0.00000000000000000000000003827576136733413 Scatter Plot
Source EPHB Target CD52 CD52 Cell-Cell Contact -0.4045 0.000000000000000000004152471990191484 Scatter Plot
Source EPHB Source PARs PARs Secreted Signaling -0.3958 0.000000000000000000033672961543695166 Scatter Plot
Source EPHB Target ICAM ICAM Cell-Cell Contact -0.3952 0.0000000000000000000386097988896049 Scatter Plot
Source EPHB Target CXCL CXCL Secreted Signaling -0.3444 0.000000000000002269762601268012 Scatter Plot
Source EPHB Target CSF CSF Secreted Signaling -0.3388 0.000000000000006803785615218609 Scatter Plot
Source EPHB Source VISTA VISTA Cell-Cell Contact -0.3304 0.000000000000033622894162743755 Scatter Plot
Source EPHB Target IFN-II IFN-II Secreted Signaling -0.3278 0.000000000000054481201106264105 Scatter Plot
Source EPHB Target CCL CCL Secreted Signaling -0.3201 0.00000000000022381660914978106 Scatter Plot
Source EPHB Target VCAM VCAM Cell-Cell Contact -0.3058 0.0000000000027445111546010256 Scatter Plot
Source EPHB Target CLEC CLEC Cell-Cell Contact -0.2901 0.00000000003744848360426759 Scatter Plot
Source EPHB Source CCL CCL Secreted Signaling -0.2757 0.00000000035470593441372085 Scatter Plot
Source EPHB Source MIF MIF Secreted Signaling -0.2722 0.0000000006076888978030922 Scatter Plot
Source EPHB Source ANNEXIN ANNEXIN Secreted Signaling -0.2601 0.000000003568686143039328 Scatter Plot
Source EPHB Source APP APP Cell-Cell Contact -0.2590 0.000000004174543729998518 Scatter Plot
Source EPHB Target IL17 IL17 Secreted Signaling -0.2539 0.000000008555769020625437 Scatter Plot
Source EPHB Source CLEC CLEC Cell-Cell Contact -0.2537 0.000000008804559284684799 Scatter Plot
Source EPHB Source NCAM NCAM Cell-Cell Contact -0.2503 0.000000013936824291102769 Scatter Plot
Target EPHB Target CD52 CD52 Cell-Cell Contact -0.2458 0.00000002584769322124389 Scatter Plot
Source EPHB Target CEACAM CEACAM Cell-Cell Contact -0.2421 0.0000000423032397786264 Scatter Plot
Target EPHB Target VCAM VCAM Cell-Cell Contact -0.2369 0.00000008274279073775461 Scatter Plot
Source EPHB Source SPP1 SPP1 Secreted Signaling -0.2297 0.0000002068808608599275 Scatter Plot
Source EPHB Target SEMA3 SEMA3 Secreted Signaling -0.2255 0.0000003479946929963416 Scatter Plot
Source EPHB Source LAIR1 LAIR1 Cell-Cell Contact -0.2223 0.0000005129858408783231 Scatter Plot
Target EPHB Target CEACAM CEACAM Cell-Cell Contact -0.2142 0.0000013403777544800425 Scatter Plot
Source EPHB Target COMPLEMENT COMPLEMENT Secreted Signaling -0.2023 0.00000515223918668224 Scatter Plot
Target EPHB Target CSF CSF Secreted Signaling -0.1881 0.000022905681749595157 Scatter Plot
Source EPHB Target SELPLG SELPLG Cell-Cell Contact -0.1843 0.00003389899597360411 Scatter Plot
Source EPHB Target ANNEXIN ANNEXIN Secreted Signaling -0.1842 0.00003421852393053364 Scatter Plot
Source EPHB Source TNF TNF Secreted Signaling -0.1762 0.00007459287469357353 Scatter Plot
Source EPHB Source VISFATIN VISFATIN Secreted Signaling -0.1747 0.00008598032171964725 Scatter Plot
Source EPHB Target VEGF VEGF Secreted Signaling -0.1601 0.0003266856029426 Scatter Plot
Target EPHB Target IFN-II IFN-II Secreted Signaling -0.1567 0.0004364368073366 Scatter Plot
Source EPHB Target COLLAGEN COLLAGEN ECM-Receptor -0.1557 0.0004758262180636 Scatter Plot
Target EPHB Target CCL CCL Secreted Signaling -0.1407 0.0016159005067425 Scatter Plot
Source EPHB Source SELPLG SELPLG Cell-Cell Contact -0.1260 0.0047708614081533 Scatter Plot
Target EPHB Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1238 0.0055679854918966 Scatter Plot
Source EPHB Source NKG2D NKG2D Cell-Cell Contact -0.1210 0.006764885549244 Scatter Plot
Target EPHB Target GRN GRN Secreted Signaling -0.1201 0.0071706322540854 Scatter Plot
Target EPHB Target CLEC CLEC Cell-Cell Contact -0.1127 0.0116934162037959 Scatter Plot
Source EPHB Source FN1 FN1 ECM-Receptor -0.1100 0.0138304325169826 Scatter Plot
Source EPHB Target GRN GRN Secreted Signaling -0.1095 0.0143037731998148 Scatter Plot
Target EPHB Target VEGF VEGF Secreted Signaling -0.1052 0.0185790603253945 Scatter Plot
Target EPHB Target ANNEXIN ANNEXIN Secreted Signaling -0.1048 0.0191221579813008 Scatter Plot
Source EPHB Target SELE SELE Cell-Cell Contact -0.1030 0.0212481063619599 Scatter Plot

Cells that are targets of EPHB from HSCs*

Cells that are source of EPHB to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.