Pathway: BMP

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Secreted Signaling

Details on the BMP pathway:

Specificity Index HSPC as target: 0.287
HSPC as source: 0.497

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the BMP pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target BMP Source FN1 FN1 ECM-Receptor 0.1016 0.0230961352859628 Scatter Plot
Target BMP Source AGRN AGRN ECM-Receptor 0.1127 0.0116413222786546 Scatter Plot
Target BMP Source OSM OSM Secreted Signaling 0.1210 0.0067657305495465 Scatter Plot
Target BMP Source IL6 IL6 Secreted Signaling 0.1265 0.0046137565795334 Scatter Plot
Target BMP Source GP1BA GP1BA Cell-Cell Contact 0.1335 0.0027882171753383 Scatter Plot
Target BMP Target VEGF VEGF Secreted Signaling 0.1416 0.0015071816733271 Scatter Plot
Target BMP Source PTN PTN Secreted Signaling 0.1452 0.0011264618820584 Scatter Plot
Target BMP Source VCAM VCAM Cell-Cell Contact 0.1576 0.000402685397863 Scatter Plot
Source BMP Source PTN PTN Secreted Signaling 0.1582 0.0003838582359775 Scatter Plot
Source BMP Source IL6 IL6 Secreted Signaling 0.1657 0.0001983124621234 Scatter Plot
Target BMP Target EPHA EPHA Cell-Cell Contact 0.1661 0.0001912604875974 Scatter Plot
Target BMP Source NT NT Secreted Signaling 0.1745 0.0000879257991456218 Scatter Plot
Target BMP Source SEMA6 SEMA6 Cell-Cell Contact 0.1749 0.00008451447292769363 Scatter Plot
Target BMP Target NCAM NCAM Cell-Cell Contact 0.1841 0.00003433084848605971 Scatter Plot
Source BMP Source WNT WNT Secreted Signaling 0.2100 0.000002171199663069933 Scatter Plot
Target BMP Source THY1 THY1 Cell-Cell Contact 0.2104 0.000002072448417543343 Scatter Plot
Target BMP Source ANGPTL ANGPTL Secreted Signaling 0.2161 0.00000107697235212515 Scatter Plot
Source BMP Source SEMA6 SEMA6 Cell-Cell Contact 0.2242 0.0000004068584380720549 Scatter Plot
Target BMP Source WNT WNT Secreted Signaling 0.2263 0.0000003157184656945194 Scatter Plot
Source BMP Source VEGF VEGF Secreted Signaling 0.2347 0.00000010977417143125133 Scatter Plot
Target BMP Source GDF GDF Secreted Signaling 0.2396 0.000000058672704718981256 Scatter Plot
Source BMP Source APELIN APELIN Secreted Signaling 0.2493 0.000000015939811705461143 Scatter Plot
Target BMP Source APELIN APELIN Secreted Signaling 0.2533 0.000000009302416308017162 Scatter Plot
Source BMP Source ncWNT ncWNT Secreted Signaling 0.2573 0.000000005304144403816636 Scatter Plot
Target BMP Source CD1D2 CD1D2 Cell-Cell Contact 0.2597 0.0000000037815854345972565 Scatter Plot
Target BMP Source VEGF VEGF Secreted Signaling 0.2658 0.000000001555630646387916 Scatter Plot
Target BMP Source LIGHT LIGHT Secreted Signaling 0.2677 0.0000000011745861827100134 Scatter Plot
Target BMP Source CD86 CD86 Cell-Cell Contact 0.2694 0.0000000009196393802498473 Scatter Plot
Source BMP Source SEMA3 SEMA3 Secreted Signaling 0.2695 0.0000000009009401753828883 Scatter Plot
Target BMP Source SEMA3 SEMA3 Secreted Signaling 0.2699 0.0000000008602841638266687 Scatter Plot
Target BMP Source IL16 IL16 Secreted Signaling 0.2719 0.0000000006327643776282806 Scatter Plot
Target BMP Source CD46 CD46 Cell-Cell Contact 0.2836 0.00000000010504127932209474 Scatter Plot
Target BMP Source RANKL RANKL Secreted Signaling 0.2846 0.00000000008962299030998613 Scatter Plot
Target BMP Target SEMA7 SEMA7 Cell-Cell Contact 0.2862 0.00000000006999489264612023 Scatter Plot
Target BMP Source CCL CCL Secreted Signaling 0.2866 0.00000000006605845505996673 Scatter Plot
Target BMP Source IL2 IL2 Secreted Signaling 0.2881 0.00000000005187958016174559 Scatter Plot
Target BMP Source CXCL CXCL Secreted Signaling 0.2883 0.000000000050322019740253265 Scatter Plot
Target BMP Source LAMININ LAMININ ECM-Receptor 0.2919 0.000000000027945053330107728 Scatter Plot
Target BMP Source LCK LCK Cell-Cell Contact 0.2965 0.000000000013238094516407694 Scatter Plot
Target BMP Target THBS THBS ECM-Receptor 0.2987 0.000000000009143131917733336 Scatter Plot
Target BMP Source CD39 CD39 Cell-Cell Contact 0.2995 0.000000000008053666029415388 Scatter Plot
Source BMP Source CADM CADM Cell-Cell Contact 0.3098 0.0000000000013764431019381202 Scatter Plot
Target BMP Source NOTCH NOTCH Cell-Cell Contact 0.3139 0.0000000000006820504493277435 Scatter Plot
Target BMP Source CD45 CD45 Cell-Cell Contact 0.3148 0.0000000000005798246963557344 Scatter Plot
Target BMP Source PROS PROS Secreted Signaling 0.3178 0.00000000000033905493259969973 Scatter Plot
Target BMP Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.3186 0.00000000000029387616258348543 Scatter Plot
Target BMP Target EPHB EPHB Cell-Cell Contact 0.3216 0.0000000000001701371197642313 Scatter Plot
Target BMP Source EPHB EPHB Cell-Cell Contact 0.3245 0.00000000000010040461780386733 Scatter Plot
Source BMP Source CXCL CXCL Secreted Signaling 0.3311 0.00000000000002914298201677561 Scatter Plot
Target BMP Source ICAM ICAM Cell-Cell Contact 0.3353 0.000000000000013372620160253732 Scatter Plot
Target BMP Source FLT3 FLT3 Secreted Signaling 0.3513 0.0000000000000005701734062036405 Scatter Plot
Target BMP Target VWF VWF ECM-Receptor 0.3514 0.0000000000000005534965781969472 Scatter Plot
Target BMP Source LIFR LIFR Secreted Signaling 0.3555 0.000000000000000242323604685349 Scatter Plot
Target BMP Target CSPG4 CSPG4 Cell-Cell Contact 0.3618 0.00000000000000006495232745828331 Scatter Plot
Target BMP Target CADM CADM Cell-Cell Contact 0.3654 0.00000000000000003052727290929955 Scatter Plot
Target BMP Source CADM CADM Cell-Cell Contact 0.3654 0.000000000000000030527272909298895 Scatter Plot
Target BMP Source PSAP PSAP Secreted Signaling 0.3703 0.000000000000000010572255384458965 Scatter Plot
Target BMP Source CDH CDH Cell-Cell Contact 0.3753 0.0000000000000000035914118377066186 Scatter Plot
Target BMP Source BST2 BST2 Cell-Cell Contact 0.3800 0.00000000000000000127544751205917 Scatter Plot
Target BMP Source MK MK Secreted Signaling 0.3809 0.0000000000000000010406713765360382 Scatter Plot
Target BMP Target PERIOSTIN PERIOSTIN Secreted Signaling 0.3814 0.0000000000000000009316560862053757 Scatter Plot
Target BMP Source CSF CSF Secreted Signaling 0.3825 0.0000000000000000007145298485851544 Scatter Plot
Target BMP Source CX3C CX3C Secreted Signaling 0.3831 0.0000000000000000006322024652364086 Scatter Plot
Source BMP Source LIGHT LIGHT Secreted Signaling 0.3854 0.0000000000000000003695534866847205 Scatter Plot
Target BMP Source PDGF PDGF Secreted Signaling 0.3960 0.00000000000000000003207104753655734 Scatter Plot
Target BMP Target DMP1 DMP1 ECM-Receptor 0.3974 0.000000000000000000022850722296252198 Scatter Plot
Target BMP Source IGF IGF Secreted Signaling 0.4009 0.000000000000000000009937537344371474 Scatter Plot
Target BMP Target BSP BSP ECM-Receptor 0.4050 0.000000000000000000003637870067320029 Scatter Plot
Source BMP Source LAMININ LAMININ ECM-Receptor 0.4173 0.00000000000000000000017280169007425114 Scatter Plot
Source BMP Source RANKL RANKL Secreted Signaling 0.4187 0.00000000000000000000011934169868672384 Scatter Plot
Target BMP Source IL7 IL7 Secreted Signaling 0.4190 0.00000000000000000000011221144543719432 Scatter Plot
Source BMP Source EPHB EPHB Cell-Cell Contact 0.4366 0.0000000000000000000000010833870548269887 Scatter Plot
Target BMP Source TWEAK TWEAK Secreted Signaling 0.4549 0.000000000000000000000000006477699886865425 Scatter Plot
Target BMP Source COLLAGEN COLLAGEN ECM-Receptor 0.4603 0.0000000000000000000000000013725794681411595 Scatter Plot
Target BMP Target CD34 CD34 Cell-Cell Contact 0.4674 0.00000000000000000000000000016687986109795431 Scatter Plot
Target BMP Source SEMA7 SEMA7 Cell-Cell Contact 0.4752 0.000000000000000000000000000015380063954773316 Scatter Plot
Target BMP Source MHC-I MHC-I Cell-Cell Contact 0.4770 0.000000000000000000000000000008969834050984942 Scatter Plot
Target BMP Source ANGPT ANGPT Secreted Signaling 0.4902 0.00000000000000000000000000000013745703813433803 Scatter Plot
Target BMP Target WNT WNT Secreted Signaling 0.4906 0.0000000000000000000000000000001185708096341847 Scatter Plot
Target BMP Source ESAM ESAM Cell-Cell Contact 0.5045 0.0000000000000000000000000000000011819873442026745 Scatter Plot
Target BMP Source MHC-II MHC-II Cell-Cell Contact 0.5062 0.0000000000000000000000000000000006760082296862903 Scatter Plot
Target BMP Source JAM JAM Cell-Cell Contact 0.5211 0.000000000000000000000000000000000003593284198425268 Scatter Plot
Source BMP Source LIFR LIFR Secreted Signaling 0.5238 0.0000000000000000000000000000000000013674202048062812 Scatter Plot
Target BMP Source GAS GAS Secreted Signaling 0.5528 0.000000000000000000000000000000000000000023026304568200646 Scatter Plot
Source BMP Source TWEAK TWEAK Secreted Signaling 0.5990 0.0000000000000000000000000000000000000000000000000504096136421439 Scatter Plot
Source BMP Source PDGF PDGF Secreted Signaling 0.6175 0.000000000000000000000000000000000000000000000000000006712310451575372 Scatter Plot
Source BMP Source ANGPT ANGPT Secreted Signaling 0.6288 0.000000000000000000000000000000000000000000000000000000020614819108015843 Scatter Plot
Source BMP Source JAM JAM Cell-Cell Contact 0.7118 0.0000000000000000000000000000000000000000000000000000000000000000000000000000018261277979177724 Scatter Plot
Source BMP Source SELL SELL Cell-Cell Contact -0.3779 0.0000000000000000020285268134177936 Scatter Plot
Source BMP Source TGFb TGFb Secreted Signaling -0.3669 0.000000000000000021991028506782178 Scatter Plot
Target BMP Source CD52 CD52 Cell-Cell Contact -0.3529 0.0000000000000004100012096402985 Scatter Plot
Target BMP Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.3515 0.0000000000000005471008523886402 Scatter Plot
Target BMP Source PARs PARs Secreted Signaling -0.2819 0.00000000013690260295825935 Scatter Plot
Source BMP Source ANGPTL ANGPTL Secreted Signaling -0.2760 0.0000000003432789722297141 Scatter Plot
Target BMP Source TGFb TGFb Secreted Signaling -0.2595 0.0000000038869696200485954 Scatter Plot
Target BMP Source COMPLEMENT COMPLEMENT Secreted Signaling -0.2447 0.0000000299039902024992 Scatter Plot
Target BMP Source SELL SELL Cell-Cell Contact -0.2446 0.0000000302532892605223 Scatter Plot
Source BMP Source SEMA4 SEMA4 Cell-Cell Contact -0.2358 0.0000000957419258177568 Scatter Plot
Target BMP Source CLEC CLEC Cell-Cell Contact -0.2207 0.0000006188949845779892 Scatter Plot
Source BMP Source NCAM NCAM Cell-Cell Contact -0.2117 0.000001794816054199522 Scatter Plot
Target BMP Source MIF MIF Secreted Signaling -0.2115 0.0000018204578445546816 Scatter Plot
Target BMP Source SEMA4 SEMA4 Cell-Cell Contact -0.1679 0.0001615385356289 Scatter Plot
Target BMP Source NKG2D NKG2D Cell-Cell Contact -0.1642 0.0002260605165719 Scatter Plot
Target BMP Source ANGPTL ANGPTL Secreted Signaling -0.1553 0.000490185047163 Scatter Plot
Target BMP Source VISTA VISTA Cell-Cell Contact -0.1516 0.0006683820101206 Scatter Plot
Target BMP Source NCAM NCAM Cell-Cell Contact -0.1449 0.0011544431805291 Scatter Plot
Target BMP Target GRN GRN Secreted Signaling -0.1429 0.0013530738162851 Scatter Plot
Target BMP Target COLLAGEN COLLAGEN ECM-Receptor -0.1400 0.0017004474982145 Scatter Plot
Target BMP Source SPP1 SPP1 Secreted Signaling -0.1256 0.0049097089165559 Scatter Plot
Target BMP Source IL1 IL1 Secreted Signaling -0.1222 0.006203251956822 Scatter Plot
Target BMP Source SELPLG SELPLG Cell-Cell Contact -0.1158 0.0095402081797916 Scatter Plot
Source BMP Source VISFATIN VISFATIN Secreted Signaling -0.1144 0.0104455436703702 Scatter Plot
Target BMP Source LAIR1 LAIR1 Cell-Cell Contact -0.1137 0.0109805581835422 Scatter Plot
Target BMP Source CCL CCL Secreted Signaling -0.1099 0.0139336639116059 Scatter Plot
Target BMP Source TNF TNF Secreted Signaling -0.0973 0.0295395057256516 Scatter Plot
Target BMP Target IL1 IL1 Secreted Signaling 0.1083 0.0153887619277112 Scatter Plot
Target BMP Target PDGF PDGF Secreted Signaling 0.1089 0.0148810956045252 Scatter Plot
Source BMP Target TWEAK TWEAK Secreted Signaling 0.1216 0.0064695663919644 Scatter Plot
Target BMP Target RANKL RANKL Secreted Signaling 0.1258 0.0048457266073528 Scatter Plot
Target BMP Target GALECTIN GALECTIN Secreted Signaling 0.1337 0.0027313665796411 Scatter Plot
Source BMP Target NOTCH NOTCH Cell-Cell Contact 0.1428 0.0013626648370082 Scatter Plot
Source BMP Target GALECTIN GALECTIN Secreted Signaling 0.1465 0.0010214335977513 Scatter Plot
Source BMP Source ICOS ICOS Cell-Cell Contact 0.1551 0.0005004999511535 Scatter Plot
Source BMP Source GP1BA GP1BA Cell-Cell Contact 0.1551 0.0004986666500334 Scatter Plot
Source BMP Source GDF GDF Secreted Signaling 0.1579 0.000394945121219 Scatter Plot
Source BMP Source THBS THBS ECM-Receptor 0.1637 0.0002376232708985 Scatter Plot
Source BMP Target GAS GAS Secreted Signaling 0.1641 0.000229479657386 Scatter Plot
Target BMP Target THY1 THY1 Cell-Cell Contact 0.1753 0.00008161443486143403 Scatter Plot
Target BMP Target PTN PTN Secreted Signaling 0.1773 0.00006685206980402836 Scatter Plot
Target BMP Target MK MK Secreted Signaling 0.1815 0.00004477066657497225 Scatter Plot
Source BMP Source THY1 THY1 Cell-Cell Contact 0.1861 0.000028122001710945583 Scatter Plot
Source BMP Source ANGPTL ANGPTL Secreted Signaling 0.1924 0.000014737448136370231 Scatter Plot
Source BMP Target NODAL NODAL Secreted Signaling 0.1934 0.00001330186650783324 Scatter Plot
Source BMP Source VCAM VCAM Cell-Cell Contact 0.1960 0.000010149257453785449 Scatter Plot
Source BMP Target THY1 THY1 Cell-Cell Contact 0.2019 0.000005352196433045352 Scatter Plot
Target BMP Target CD23 CD23 Cell-Cell Contact 0.2034 0.000004567165707622712 Scatter Plot
Target BMP Target FN1 FN1 ECM-Receptor 0.2059 0.000003449631272426934 Scatter Plot
Target BMP Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2103 0.0000020949268406293383 Scatter Plot
Target BMP Target SEMA3 SEMA3 Secreted Signaling 0.2116 0.0000018079372133659528 Scatter Plot
Source BMP Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2171 0.0000009552994497579393 Scatter Plot
Source BMP Target CD23 CD23 Cell-Cell Contact 0.2181 0.0000008421770026108825 Scatter Plot
Source BMP Target VEGF VEGF Secreted Signaling 0.2198 0.0000006940031825302663 Scatter Plot
Source BMP Source CD1D2 CD1D2 Cell-Cell Contact 0.2232 0.0000004606711799731513 Scatter Plot
Target BMP Target COLLAGEN COLLAGEN ECM-Receptor 0.2269 0.0000002936731345888523 Scatter Plot
Target BMP Target SPP1 SPP1 Secreted Signaling 0.2295 0.0000002132733560917166 Scatter Plot
Source BMP Target SEMA3 SEMA3 Secreted Signaling 0.2328 0.0000001395088730192939 Scatter Plot
Target BMP Target OSM OSM Secreted Signaling 0.2336 0.00000012610075836303646 Scatter Plot
Source BMP Target AGT AGT Secreted Signaling 0.2357 0.00000009680981189268256 Scatter Plot
Target BMP Target IL6 IL6 Secreted Signaling 0.2366 0.0000000863420335811012 Scatter Plot
Source BMP Target COLLAGEN COLLAGEN ECM-Receptor 0.2447 0.00000002967042632758592 Scatter Plot
Source BMP Target GDF GDF Secreted Signaling 0.2490 0.000000016799051672505885 Scatter Plot
Source BMP Target EPHA EPHA Cell-Cell Contact 0.2510 0.000000012772327541490816 Scatter Plot
Source BMP Target IL6 IL6 Secreted Signaling 0.2578 0.000000004927605387141743 Scatter Plot
Source BMP Target SPP1 SPP1 Secreted Signaling 0.2650 0.0000000017522713233862147 Scatter Plot
Source BMP Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2680 0.0000000011319661411673439 Scatter Plot
Source BMP Target FN1 FN1 ECM-Receptor 0.2710 0.0000000007231236026005098 Scatter Plot
Source BMP Target PTN PTN Secreted Signaling 0.2760 0.00000000034038791351765384 Scatter Plot
Source BMP Target RANKL RANKL Secreted Signaling 0.2871 0.00000000006063290736392159 Scatter Plot
Target BMP Target ANGPTL ANGPTL Secreted Signaling 0.2887 0.000000000046726186856007 Scatter Plot
Source BMP Source CD39 CD39 Cell-Cell Contact 0.2896 0.0000000000409447181436396 Scatter Plot
Target BMP Target NPR2 NPR2 Secreted Signaling 0.2897 0.00000000004012792999576116 Scatter Plot
Source BMP Target MK MK Secreted Signaling 0.2929 0.000000000023893012119013 Scatter Plot
Source BMP Source CCL CCL Secreted Signaling 0.2935 0.000000000021464016194749915 Scatter Plot
Target BMP Target SEMA6 SEMA6 Cell-Cell Contact 0.2979 0.000000000010551128730057443 Scatter Plot
Target BMP Target AGT AGT Secreted Signaling 0.3059 0.0000000000027152764187341146 Scatter Plot
Target BMP Target PARs PARs Secreted Signaling 0.3084 0.0000000000017522322839691622 Scatter Plot
Source BMP Target CADM CADM Cell-Cell Contact 0.3098 0.0000000000013764431019381202 Scatter Plot
Source BMP Target OSM OSM Secreted Signaling 0.3120 0.000000000000938415393521738 Scatter Plot
Target BMP Target COMPLEMENT COMPLEMENT Secreted Signaling 0.3133 0.0000000000007575435741454441 Scatter Plot
Target BMP Target CD22 CD22 Cell-Cell Contact 0.3148 0.0000000000005798246963557281 Scatter Plot
Target BMP Target VISFATIN VISFATIN Secreted Signaling 0.3175 0.0000000000003589029953219344 Scatter Plot
Source BMP Source IL16 IL16 Secreted Signaling 0.3207 0.00000000000019871948058487786 Scatter Plot
Source BMP Target NCAM NCAM Cell-Cell Contact 0.3221 0.00000000000015469507884884985 Scatter Plot
Target BMP Target VTN VTN ECM-Receptor 0.3412 0.000000000000004230841714106543 Scatter Plot
Target BMP Target BAFF BAFF Secreted Signaling 0.3432 0.000000000000002867311905440563 Scatter Plot
Target BMP Target KIT KIT Secreted Signaling 0.3498 0.00000000000000077028414292116 Scatter Plot
Target BMP Target LAMININ LAMININ ECM-Receptor 0.3517 0.000000000000000523417007677283 Scatter Plot
Source BMP Target ANGPTL ANGPTL Secreted Signaling 0.3522 0.0000000000000004759450829205139 Scatter Plot
Source BMP Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.3548 0.00000000000000027742535346953983 Scatter Plot
Source BMP Source CD46 CD46 Cell-Cell Contact 0.3583 0.0000000000000001357204839633912 Scatter Plot
Target BMP Target SEMA5 SEMA5 Cell-Cell Contact 0.3594 0.00000000000000010745869552715975 Scatter Plot
Source BMP Target SEMA5 SEMA5 Cell-Cell Contact 0.3645 0.0000000000000000371916735582876 Scatter Plot
Source BMP Target CSPG4 CSPG4 Cell-Cell Contact 0.3685 0.00000000000000001570380593782401 Scatter Plot
Source BMP Target SEMA6 SEMA6 Cell-Cell Contact 0.3685 0.000000000000000015587299674320057 Scatter Plot
Source BMP Target KIT KIT Secreted Signaling 0.3725 0.000000000000000006660621419243545 Scatter Plot
Source BMP Target ACTIVIN ACTIVIN Secreted Signaling 0.3730 0.000000000000000005923988688493991 Scatter Plot
Source BMP Source IL2 IL2 Secreted Signaling 0.3732 0.000000000000000005649682104391816 Scatter Plot
Target BMP Target CDH CDH Cell-Cell Contact 0.3753 0.0000000000000000035914118377066186 Scatter Plot
Target BMP Target NRG NRG Secreted Signaling 0.3768 0.0000000000000000025917930745628307 Scatter Plot
Source BMP Source CD86 CD86 Cell-Cell Contact 0.3825 0.0000000000000000007190278983498605 Scatter Plot
Source BMP Target SEMA7 SEMA7 Cell-Cell Contact 0.3843 0.0000000000000000004764442561455257 Scatter Plot
Target BMP Target BSP BSP ECM-Receptor 0.3878 0.0000000000000000002170754502086898 Scatter Plot
Target BMP Target IGF IGF Secreted Signaling 0.3893 0.00000000000000000015177677114326137 Scatter Plot
Source BMP Target BAFF BAFF Secreted Signaling 0.3904 0.00000000000000000011869152410418242 Scatter Plot
Source BMP Source ICAM ICAM Cell-Cell Contact 0.3992 0.000000000000000000014999958073360105 Scatter Plot
Source BMP Source LCK LCK Cell-Cell Contact 0.4022 0.000000000000000000007222406185805562 Scatter Plot
Source BMP Source NOTCH NOTCH Cell-Cell Contact 0.4027 0.000000000000000000006361773466189124 Scatter Plot
Target BMP Target TENASCIN TENASCIN ECM-Receptor 0.4048 0.00000000000000000000382198742014363 Scatter Plot
Source BMP Target THBS THBS ECM-Receptor 0.4072 0.0000000000000000000021360206734891707 Scatter Plot
Source BMP Target TGFb TGFb Secreted Signaling 0.4109 0.0000000000000000000008640653869557542 Scatter Plot
Target BMP Target SEMA4 SEMA4 Cell-Cell Contact 0.4148 0.00000000000000000000032516447442295226 Scatter Plot
Target BMP Target SLURP SLURP Secreted Signaling 0.4181 0.00000000000000000000013958558258788713 Scatter Plot
Source BMP Target LAMININ LAMININ ECM-Receptor 0.4187 0.00000000000000000000011920991841115686 Scatter Plot
Target BMP Target ANGPT ANGPT Secreted Signaling 0.4190 0.00000000000000000000011163694814407614 Scatter Plot
Source BMP Target CD22 CD22 Cell-Cell Contact 0.4221 0.000000000000000000000049648012905394243 Scatter Plot
Source BMP Source CD45 CD45 Cell-Cell Contact 0.4221 0.000000000000000000000049648012905394243 Scatter Plot
Target BMP Target CD200 CD200 Cell-Cell Contact 0.4273 0.000000000000000000000012908859038354389 Scatter Plot
Source BMP Source CSF CSF Secreted Signaling 0.4297 0.000000000000000000000006799983025437695 Scatter Plot
Source BMP Target EPHB EPHB Cell-Cell Contact 0.4338 0.000000000000000000000002282455495068106 Scatter Plot
Source BMP Target VISFATIN VISFATIN Secreted Signaling 0.4356 0.0000000000000000000000014274749107022663 Scatter Plot
Target BMP Target FGF FGF Secreted Signaling 0.4359 0.0000000000000000000000013250509316275647 Scatter Plot
Source BMP Source NT NT Secreted Signaling 0.4365 0.0000000000000000000000011101316582530176 Scatter Plot
Source BMP Target SEMA4 SEMA4 Cell-Cell Contact 0.4371 0.0000000000000000000000009410293013952346 Scatter Plot
Target BMP Target MIF MIF Secreted Signaling 0.4452 0.00000000000000000000000010069474762318543 Scatter Plot
Source BMP Source CX3C CX3C Secreted Signaling 0.4464 0.00000000000000000000000007280172179372887 Scatter Plot
Target BMP Target APP APP Cell-Cell Contact 0.4504 0.000000000000000000000000023724268325093807 Scatter Plot
Source BMP Target VTN VTN ECM-Receptor 0.4555 0.0000000000000000000000000055477358045752926 Scatter Plot
Source BMP Source PSAP PSAP Secreted Signaling 0.4578 0.0000000000000000000000000028132644744797806 Scatter Plot
Target BMP Target ncWNT ncWNT Secreted Signaling 0.4616 0.0000000000000000000000000009200980196943007 Scatter Plot
Target BMP Target JAM JAM Cell-Cell Contact 0.4792 0.000000000000000000000000000004509302534180664 Scatter Plot
Source BMP Target PARs PARs Secreted Signaling 0.4813 0.0000000000000000000000000000023079185085580693 Scatter Plot
Target BMP Target CD39 CD39 Cell-Cell Contact 0.4847 0.0000000000000000000000000000007892351615443962 Scatter Plot
Source BMP Target VWF VWF ECM-Receptor 0.4874 0.00000000000000000000000000000033498656664571908 Scatter Plot
Source BMP Target PERIOSTIN PERIOSTIN Secreted Signaling 0.4911 0.00000000000000000000000000000010305884737455446 Scatter Plot
Source BMP Target CDH CDH Cell-Cell Contact 0.4977 0.000000000000000000000000000000011627354881682624 Scatter Plot
Source BMP Source CDH CDH Cell-Cell Contact 0.4977 0.000000000000000000000000000000011627354881682624 Scatter Plot
Source BMP Source MK MK Secreted Signaling 0.5000 0.000000000000000000000000000000005474153111131704 Scatter Plot
Target BMP Target ESAM ESAM Cell-Cell Contact 0.5045 0.0000000000000000000000000000000011819873442026745 Scatter Plot
Source BMP Target ANGPT ANGPT Secreted Signaling 0.5054 0.0000000000000000000000000000000008713126784835644 Scatter Plot
Source BMP Target NRG NRG Secreted Signaling 0.5063 0.0000000000000000000000000000000006428127801081469 Scatter Plot
Source BMP Target BSP BSP ECM-Receptor 0.5064 0.0000000000000000000000000000000006258093472571245 Scatter Plot
Source BMP Target DMP1 DMP1 ECM-Receptor 0.5119 0.00000000000000000000000000000000009398231623242643 Scatter Plot
Source BMP Source FLT3 FLT3 Secreted Signaling 0.5205 0.0000000000000000000000000000000000045882120946579896 Scatter Plot
Source BMP Target NPR2 NPR2 Secreted Signaling 0.5205 0.000000000000000000000000000000000004587138293233659 Scatter Plot
Source BMP Source PROS PROS Secreted Signaling 0.5283 0.00000000000000000000000000000000000027078732997991065 Scatter Plot
Source BMP Source IGF IGF Secreted Signaling 0.5299 0.00000000000000000000000000000000000014970020132846778 Scatter Plot
Source BMP Source COLLAGEN COLLAGEN ECM-Receptor 0.5365 0.000000000000000000000000000000000000012588724901977894 Scatter Plot
Source BMP Source IL7 IL7 Secreted Signaling 0.5396 0.0000000000000000000000000000000000000039578090165933516 Scatter Plot
Source BMP Target CD200 CD200 Cell-Cell Contact 0.5397 0.0000000000000000000000000000000000000037579365736279465 Scatter Plot
Source BMP Target SLURP SLURP Secreted Signaling 0.5476 0.0000000000000000000000000000000000000001797471010190228 Scatter Plot
Source BMP Target FGF FGF Secreted Signaling 0.5728 0.000000000000000000000000000000000000000000005878295594747164 Scatter Plot
Source BMP Target CD39 CD39 Cell-Cell Contact 0.5749 0.000000000000000000000000000000000000000000002435123632420638 Scatter Plot
Source BMP Target ncWNT ncWNT Secreted Signaling 0.5782 0.0000000000000000000000000000000000000000000005811226762171346 Scatter Plot
Source BMP Target TENASCIN TENASCIN ECM-Receptor 0.5798 0.0000000000000000000000000000000000000000000002944048750332848 Scatter Plot
Source BMP Target IGF IGF Secreted Signaling 0.5799 0.00000000000000000000000000000000000000000000028040145929269127 Scatter Plot
Source BMP Source BST2 BST2 Cell-Cell Contact 0.5813 0.00000000000000000000000000000000000000000000014810958086241732 Scatter Plot
Source BMP Target WNT WNT Secreted Signaling 0.5876 0.000000000000000000000000000000000000000000000009330629899461767 Scatter Plot
Source BMP Target APP APP Cell-Cell Contact 0.5898 0.000000000000000000000000000000000000000000000003415131302138515 Scatter Plot
Source BMP Target MIF MIF Secreted Signaling 0.6041 0.000000000000000000000000000000000000000000000000004549080259462026 Scatter Plot
Source BMP Source SEMA7 SEMA7 Cell-Cell Contact 0.6051 0.0000000000000000000000000000000000000000000000000027729995953235495 Scatter Plot
Source BMP Source GAS GAS Secreted Signaling 0.6123 0.0000000000000000000000000000000000000000000000000000846852548897497 Scatter Plot
Source BMP Target CD34 CD34 Cell-Cell Contact 0.6382 0.00000000000000000000000000000000000000000000000000000000014115524868672538 Scatter Plot
Source BMP Source ESAM ESAM Cell-Cell Contact 0.6538 0.000000000000000000000000000000000000000000000000000000000000025287239558779564 Scatter Plot
Source BMP Target ESAM ESAM Cell-Cell Contact 0.6538 0.000000000000000000000000000000000000000000000000000000000000025287239558776693 Scatter Plot
Source BMP Target JAM JAM Cell-Cell Contact 0.6586 0.0000000000000000000000000000000000000000000000000000000000000015667636238187456 Scatter Plot
Source BMP Source MHC-II MHC-II Cell-Cell Contact 0.6681 0.000000000000000000000000000000000000000000000000000000000000000005651461224339224 Scatter Plot
Source BMP Source MHC-I MHC-I Cell-Cell Contact 0.6975 0.00000000000000000000000000000000000000000000000000000000000000000000000003881858173501952 Scatter Plot
Source BMP Source CD52 CD52 Cell-Cell Contact -0.5730 0.000000000000000000000000000000000000000000005464181627510636 Scatter Plot
Source BMP Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.4925 0.00000000000000000000000000000006516009515581794 Scatter Plot
Source BMP Target ICAM ICAM Cell-Cell Contact -0.4644 0.0000000000000000000000000004066354071013954 Scatter Plot
Source BMP Source COMPLEMENT COMPLEMENT Secreted Signaling -0.4026 0.0000000000000000000065456600892027605 Scatter Plot
Source BMP Target CD52 CD52 Cell-Cell Contact -0.3782 0.000000000000000001896272804675286 Scatter Plot
Source BMP Source PARs PARs Secreted Signaling -0.3511 0.0000000000000005964952352367013 Scatter Plot
Source BMP Source MIF MIF Secreted Signaling -0.3182 0.0000000000003144981296971746 Scatter Plot
Target BMP Target CD52 CD52 Cell-Cell Contact -0.3042 0.000000000003613386652376008 Scatter Plot
Target BMP Target ICAM ICAM Cell-Cell Contact -0.3017 0.000000000005523102307469698 Scatter Plot
Source BMP Target IFN-II IFN-II Secreted Signaling -0.2864 0.00000000006780922597188938 Scatter Plot
Source BMP Target CSF CSF Secreted Signaling -0.2692 0.000000000941129726791264 Scatter Plot
Source BMP Target VCAM VCAM Cell-Cell Contact -0.2459 0.000000025235663440857177 Scatter Plot
Source BMP Target CEACAM CEACAM Cell-Cell Contact -0.2414 0.000000046129252970572216 Scatter Plot
Source BMP Target CLEC CLEC Cell-Cell Contact -0.2334 0.0000001295954574693216 Scatter Plot
Source BMP Target CXCL CXCL Secreted Signaling -0.2327 0.0000001414441766615049 Scatter Plot
Source BMP Target CCL CCL Secreted Signaling -0.2313 0.0000001692730835796509 Scatter Plot
Target BMP Target CXCL CXCL Secreted Signaling -0.2311 0.00000017304265676230725 Scatter Plot
Source BMP Target IL17 IL17 Secreted Signaling -0.2276 0.00000026907224198927804 Scatter Plot
Source BMP Source CCL CCL Secreted Signaling -0.2270 0.0000002888270159040456 Scatter Plot
Source BMP Source CLEC CLEC Cell-Cell Contact -0.2224 0.0000005081234376210216 Scatter Plot
Source BMP Source SELPLG SELPLG Cell-Cell Contact -0.2162 0.000001055059677177448 Scatter Plot
Source BMP Source VISTA VISTA Cell-Cell Contact -0.2113 0.0000018790612876394176 Scatter Plot
Source BMP Source ANNEXIN ANNEXIN Secreted Signaling -0.2069 0.0000030787663137946094 Scatter Plot
Source BMP Source SPP1 SPP1 Secreted Signaling -0.2044 0.000004045791511985364 Scatter Plot
Target BMP Target IL17 IL17 Secreted Signaling -0.1869 0.000025919283508349898 Scatter Plot
Source BMP Source TNF TNF Secreted Signaling -0.1827 0.00003952980452903107 Scatter Plot
Source BMP Source NKG2D NKG2D Cell-Cell Contact -0.1757 0.0000783931234696137 Scatter Plot
Source BMP Target GRN GRN Secreted Signaling -0.1724 0.0001067260890717 Scatter Plot
Target BMP Target CSF CSF Secreted Signaling -0.1620 0.0002750174013756 Scatter Plot
Target BMP Target VCAM VCAM Cell-Cell Contact -0.1573 0.0004135171375136 Scatter Plot
Source BMP Target COLLAGEN COLLAGEN ECM-Receptor -0.1511 0.000697707490972 Scatter Plot
Target BMP Target CCL CCL Secreted Signaling -0.1493 0.0008144176870155 Scatter Plot
Source BMP Source LAIR1 LAIR1 Cell-Cell Contact -0.1424 0.0014089978257236 Scatter Plot
Target BMP Target CEACAM CEACAM Cell-Cell Contact -0.1404 0.0016468672369336 Scatter Plot
Target BMP Target IFN-II IFN-II Secreted Signaling -0.1299 0.0036164815465864 Scatter Plot
Source BMP Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1279 0.0041821499727728 Scatter Plot
Source BMP Target VEGF VEGF Secreted Signaling -0.1264 0.0046603178494411 Scatter Plot
Target BMP Target CLEC CLEC Cell-Cell Contact -0.1136 0.0110151809108804 Scatter Plot
Target BMP Target ANNEXIN ANNEXIN Secreted Signaling -0.0977 0.0289138263253666 Scatter Plot

Cells that are targets of BMP from HSCs*

Cells that are source of BMP to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.