Pathway: GP1BA

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Cell-Cell Contact

Details on the GP1BA pathway:

Specificity Index HSPC as target:
HSPC as source:

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the GP1BA pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Source GP1BA Source THY1 THY1 Cell-Cell Contact 0.1017 0.0229890539503502 Scatter Plot
Source GP1BA Source PTN PTN Secreted Signaling 0.1055 0.0182669872571438 Scatter Plot
Source GP1BA Source LIGHT LIGHT Secreted Signaling 0.1196 0.0074337269876395 Scatter Plot
Source GP1BA Source VEGF VEGF Secreted Signaling 0.1217 0.006418023046082 Scatter Plot
Source GP1BA Source GAS GAS Secreted Signaling 0.1338 0.0027261400948576 Scatter Plot
Source GP1BA Source NT NT Secreted Signaling 0.1396 0.0017587564196624 Scatter Plot
Source GP1BA Source MHC-II MHC-II Cell-Cell Contact 0.1406 0.0016224369464017 Scatter Plot
Source GP1BA Source PROS PROS Secreted Signaling 0.1450 0.0011449442681091 Scatter Plot
Source GP1BA Source FGF FGF Secreted Signaling 0.1451 0.0011394825358176 Scatter Plot
Source GP1BA Source COLLAGEN COLLAGEN ECM-Receptor 0.1496 0.0007921334177154 Scatter Plot
Source GP1BA Source PDGF PDGF Secreted Signaling 0.1508 0.000715347461472 Scatter Plot
Source GP1BA Source BMP BMP Secreted Signaling 0.1551 0.0004986666500334 Scatter Plot
Source GP1BA Source CX3C CX3C Secreted Signaling 0.1556 0.0004792565877272 Scatter Plot
Source GP1BA Source RANKL RANKL Secreted Signaling 0.1615 0.0002868879441011 Scatter Plot
Source GP1BA Source THBS THBS ECM-Receptor 0.1622 0.0002716708130933 Scatter Plot
Source GP1BA Source CDH CDH Cell-Cell Contact 0.1645 0.0002195219666725 Scatter Plot
Source GP1BA Source IL7 IL7 Secreted Signaling 0.1686 0.0001524929763305 Scatter Plot
Source GP1BA Source TWEAK TWEAK Secreted Signaling 0.1745 0.00008764300951077067 Scatter Plot
Source GP1BA Source CADM CADM Cell-Cell Contact 0.1750 0.000083725832781358 Scatter Plot
Source GP1BA Source IGF IGF Secreted Signaling 0.1861 0.00002810531927877309 Scatter Plot
Source GP1BA Source CD46 CD46 Cell-Cell Contact 0.1882 0.000022887680670323504 Scatter Plot
Source GP1BA Source VCAM VCAM Cell-Cell Contact 0.1930 0.00001387602765165912 Scatter Plot
Source GP1BA Source JAM JAM Cell-Cell Contact 0.2013 0.000005698729228984623 Scatter Plot
Source GP1BA Source ESAM ESAM Cell-Cell Contact 0.2345 0.0000001122646953194744 Scatter Plot
Source GP1BA Source SEMA3 SEMA3 Secreted Signaling 0.2348 0.00000010899944403702645 Scatter Plot
Source GP1BA Source CCL CCL Secreted Signaling 0.2388 0.00000006494534679509948 Scatter Plot
Source GP1BA Source FLT3 FLT3 Secreted Signaling 0.2507 0.000000013222365935000348 Scatter Plot
Source GP1BA Source LIFR LIFR Secreted Signaling 0.2538 0.000000008590901202425197 Scatter Plot
Source GP1BA Source ANGPT ANGPT Secreted Signaling 0.2577 0.000000005002893170503701 Scatter Plot
Source GP1BA Source GALECTIN GALECTIN Secreted Signaling 0.2579 0.000000004871098474811792 Scatter Plot
Source GP1BA Source EPHB EPHB Cell-Cell Contact 0.2856 0.00000000007636821246971847 Scatter Plot
Source GP1BA Source VISTA VISTA Cell-Cell Contact -0.3190 0.0000000000002706987469682144 Scatter Plot
Source GP1BA Source PARs PARs Secreted Signaling -0.3106 0.0000000000012120066275487778 Scatter Plot
Source GP1BA Source SELL SELL Cell-Cell Contact -0.3086 0.0000000000017200224163983596 Scatter Plot
Source GP1BA Source CD52 CD52 Cell-Cell Contact -0.3040 0.000000000003772114347386526 Scatter Plot
Source GP1BA Source COMPLEMENT COMPLEMENT Secreted Signaling -0.2942 0.000000000019293053870489395 Scatter Plot
Source GP1BA Source SEMA4 SEMA4 Cell-Cell Contact -0.2474 0.000000020649415079507957 Scatter Plot
Source GP1BA Source APP APP Cell-Cell Contact -0.2316 0.00000016247093543324698 Scatter Plot
Source GP1BA Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.2206 0.0000006327746216200947 Scatter Plot
Source GP1BA Source GRN GRN Secreted Signaling -0.2035 0.000004480780559289843 Scatter Plot
Source GP1BA Source TNF TNF Secreted Signaling -0.1989 0.000007385251366442178 Scatter Plot
Source GP1BA Source SELPLG SELPLG Cell-Cell Contact -0.1725 0.0001061407794972 Scatter Plot
Source GP1BA Source NCAM NCAM Cell-Cell Contact -0.1324 0.0030207137401725 Scatter Plot
Source GP1BA Target APP APP Cell-Cell Contact 0.1026 0.0218043941432866 Scatter Plot
Source GP1BA Target COMPLEMENT COMPLEMENT Secreted Signaling 0.1047 0.0192142140554823 Scatter Plot
Source GP1BA Target SEMA4 SEMA4 Cell-Cell Contact 0.1096 0.0141917807886758 Scatter Plot
Source GP1BA Target EPHB EPHB Cell-Cell Contact 0.1225 0.0061130909130682 Scatter Plot
Source GP1BA Target TGFb TGFb Secreted Signaling 0.1277 0.0042492861674585 Scatter Plot
Source GP1BA Source LCK LCK Cell-Cell Contact 0.1308 0.0033977340140083 Scatter Plot
Source GP1BA Target BMP BMP Secreted Signaling 0.1335 0.0027882171753383 Scatter Plot
Source GP1BA Target NPR2 NPR2 Secreted Signaling 0.1427 0.0013739311547074 Scatter Plot
Source GP1BA Target PERIOSTIN PERIOSTIN Secreted Signaling 0.1433 0.0013167051082664 Scatter Plot
Source GP1BA Target GDF GDF Secreted Signaling 0.1487 0.0008487795630443 Scatter Plot
Source GP1BA Target THBS THBS ECM-Receptor 0.1526 0.0006173424976049 Scatter Plot
Source GP1BA Target ANGPTL ANGPTL Secreted Signaling 0.1544 0.0005297802501827 Scatter Plot
Source GP1BA Target BSP BSP ECM-Receptor 0.1571 0.000423216761902 Scatter Plot
Source GP1BA Target KIT KIT Secreted Signaling 0.1577 0.0004017486177091 Scatter Plot
Source GP1BA Source CD1D2 CD1D2 Cell-Cell Contact 0.1584 0.0003771479524765 Scatter Plot
Source GP1BA Target JAM JAM Cell-Cell Contact 0.1604 0.0003174722895593 Scatter Plot
Source GP1BA Target CDH CDH Cell-Cell Contact 0.1645 0.0002195219666725 Scatter Plot
Source GP1BA Source IL1 IL1 Secreted Signaling 0.1669 0.0001774304643026 Scatter Plot
Source GP1BA Target FGF FGF Secreted Signaling 0.1683 0.0001564768681993 Scatter Plot
Source GP1BA Target CADM CADM Cell-Cell Contact 0.1750 0.000083725832781358 Scatter Plot
Source GP1BA Target DMP1 DMP1 ECM-Receptor 0.1783 0.0000607433033667225 Scatter Plot
Source GP1BA Target AGT AGT Secreted Signaling 0.1829 0.00003869750459766465 Scatter Plot
Source GP1BA Target SEMA6 SEMA6 Cell-Cell Contact 0.1853 0.000030589507488221566 Scatter Plot
Source GP1BA Source IL2 IL2 Secreted Signaling 0.1863 0.000027701544258486967 Scatter Plot
Source GP1BA Target CD39 CD39 Cell-Cell Contact 0.1883 0.00002251901284876363 Scatter Plot
Source GP1BA Target NRG NRG Secreted Signaling 0.1891 0.000020705070310648423 Scatter Plot
Source GP1BA Target PTN PTN Secreted Signaling 0.1909 0.000017281563780443397 Scatter Plot
Source GP1BA Source CXCL CXCL Secreted Signaling 0.1964 0.00000966838958890339 Scatter Plot
Source GP1BA Target VISFATIN VISFATIN Secreted Signaling 0.2106 0.000002015573627637968 Scatter Plot
Source GP1BA Target ncWNT ncWNT Secreted Signaling 0.2207 0.0000006181927654032696 Scatter Plot
Source GP1BA Target WNT WNT Secreted Signaling 0.2208 0.0000006110029798392615 Scatter Plot
Source GP1BA Target SEMA5 SEMA5 Cell-Cell Contact 0.2283 0.00000024650471654628093 Scatter Plot
Source GP1BA Source MHC-I MHC-I Cell-Cell Contact 0.2316 0.00000016250629857194688 Scatter Plot
Source GP1BA Target IGF IGF Secreted Signaling 0.2345 0.00000011313600656558997 Scatter Plot
Source GP1BA Target ESAM ESAM Cell-Cell Contact 0.2345 0.0000001122646953194744 Scatter Plot
Source GP1BA Target LAMININ LAMININ ECM-Receptor 0.2409 0.000000049044533073438855 Scatter Plot
Source GP1BA Target SPP1 SPP1 Secreted Signaling 0.2440 0.000000032603352620767846 Scatter Plot
Source GP1BA Target ACTIVIN ACTIVIN Secreted Signaling 0.2494 0.000000015879655161023752 Scatter Plot
Source GP1BA Target VTN VTN ECM-Receptor 0.2504 0.000000013838114009378588 Scatter Plot
Source GP1BA Target TENASCIN TENASCIN ECM-Receptor 0.2577 0.0000000049949616792783965 Scatter Plot
Source GP1BA Source GALECTIN GALECTIN Secreted Signaling 0.2579 0.000000004871098474811863 Scatter Plot
Source GP1BA Target ANGPT ANGPT Secreted Signaling 0.2675 0.0000000012195709213032476 Scatter Plot
Source GP1BA Target CD34 CD34 Cell-Cell Contact 0.2734 0.000000000505919264938557 Scatter Plot
Source GP1BA Target FN1 FN1 ECM-Receptor 0.2744 0.0000000004345170365686186 Scatter Plot
Source GP1BA Target MK MK Secreted Signaling 0.2967 0.000000000012843291718051569 Scatter Plot
Source GP1BA Target SEMA7 SEMA7 Cell-Cell Contact 0.3059 0.0000000000026969730524647346 Scatter Plot
Source GP1BA Target VWF VWF ECM-Receptor 0.3996 0.000000000000000000013353165133390171 Scatter Plot
Source GP1BA Target PARs PARs Secreted Signaling 0.4184 0.0000000000000000000001309110616061783 Scatter Plot
Source GP1BA Source ANNEXIN ANNEXIN Secreted Signaling -0.3077 0.000000000002002811615088408 Scatter Plot
Source GP1BA Target CLEC CLEC Cell-Cell Contact -0.2761 0.000000000334552680635323 Scatter Plot
Source GP1BA Target IFN-II IFN-II Secreted Signaling -0.2640 0.000000002016731223983521 Scatter Plot
Source GP1BA Target CD52 CD52 Cell-Cell Contact -0.2581 0.000000004695611812670699 Scatter Plot
Source GP1BA Target CCL CCL Secreted Signaling -0.2484 0.000000018176001935066343 Scatter Plot
Source GP1BA Target CXCL CXCL Secreted Signaling -0.2471 0.000000021495349614878035 Scatter Plot
Source GP1BA Target VEGF VEGF Secreted Signaling -0.2426 0.000000039215016543432664 Scatter Plot
Source GP1BA Target CSF CSF Secreted Signaling -0.2343 0.00000011543128076261757 Scatter Plot
Source GP1BA Target ICAM ICAM Cell-Cell Contact -0.2315 0.00000016596988735491716 Scatter Plot
Source GP1BA Target VCAM VCAM Cell-Cell Contact -0.2282 0.0000002498531978296803 Scatter Plot
Source GP1BA Source LAIR1 LAIR1 Cell-Cell Contact -0.2163 0.0000010474325813927942 Scatter Plot
Source GP1BA Source SPP1 SPP1 Secreted Signaling -0.2125 0.0000016218601096004918 Scatter Plot
Source GP1BA Source CCL CCL Secreted Signaling -0.2053 0.000003692224446364004 Scatter Plot
Source GP1BA Target CEACAM CEACAM Cell-Cell Contact -0.1870 0.00002566327698913742 Scatter Plot
Source GP1BA Source CLEC CLEC Cell-Cell Contact -0.1783 0.00006084715757853343 Scatter Plot
Source GP1BA Target SEMA3 SEMA3 Secreted Signaling -0.1625 0.0002626147670029 Scatter Plot
Source GP1BA Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1544 0.0005323428849048 Scatter Plot
Source GP1BA Target IL17 IL17 Secreted Signaling -0.1480 0.0009034187611668 Scatter Plot
Source GP1BA Target GRN GRN Secreted Signaling -0.1098 0.014003303359976 Scatter Plot
Source GP1BA Target COLLAGEN COLLAGEN ECM-Receptor -0.1023 0.022176515265371 Scatter Plot
Source GP1BA Target ANNEXIN ANNEXIN Secreted Signaling -0.0962 0.0315205535806986 Scatter Plot

Cells that are targets of GP1BA from HSCs*

Cells that are source of GP1BA to HSCs*

    No cell populations

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.