Pathway: CDH

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Cell-Cell Contact

Details on the CDH pathway:

Specificity Index HSPC as target: 0.658
HSPC as source: 0.658

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the CDH pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target CDH Source THBS THBS ECM-Receptor 0.1273 0.0043636617340766 Scatter Plot
Target CDH Source ICOS ICOS Cell-Cell Contact 0.1278 0.0041996478336564 Scatter Plot
Source CDH Source CXCL CXCL Secreted Signaling 0.1298 0.0036524090576284 Scatter Plot
Target CDH Source WNT WNT Secreted Signaling 0.1313 0.0032580625421603 Scatter Plot
Source CDH Source WNT WNT Secreted Signaling 0.1313 0.0032580625421603 Scatter Plot
Target CDH Source VCAM VCAM Cell-Cell Contact 0.1414 0.0015218320088133 Scatter Plot
Target CDH Target GAS GAS Secreted Signaling 0.1448 0.0011686948546592 Scatter Plot
Target CDH Target NOTCH NOTCH Cell-Cell Contact 0.1469 0.000987632853654 Scatter Plot
Target CDH Source APELIN APELIN Secreted Signaling 0.1500 0.0007684992626005 Scatter Plot
Source CDH Source APELIN APELIN Secreted Signaling 0.1500 0.0007684992626005 Scatter Plot
Source CDH Source ncWNT ncWNT Secreted Signaling 0.1502 0.0007536742778784 Scatter Plot
Target CDH Source ncWNT ncWNT Secreted Signaling 0.1502 0.0007536742778784 Scatter Plot
Source CDH Source PTN PTN Secreted Signaling 0.1512 0.0006936934764842 Scatter Plot
Target CDH Source PTN PTN Secreted Signaling 0.1512 0.0006936934764842 Scatter Plot
Source CDH Source CCL CCL Secreted Signaling 0.1515 0.0006748995493766 Scatter Plot
Target CDH Source SEMA6 SEMA6 Cell-Cell Contact 0.1587 0.0003671547883764 Scatter Plot
Source CDH Source SEMA6 SEMA6 Cell-Cell Contact 0.1587 0.0003671547883764 Scatter Plot
Target CDH Source GP1BA GP1BA Cell-Cell Contact 0.1645 0.0002195219666725 Scatter Plot
Target CDH Target FN1 FN1 ECM-Receptor 0.1664 0.000186095741024 Scatter Plot
Source CDH Source IL6 IL6 Secreted Signaling 0.1689 0.0001476192503963 Scatter Plot
Target CDH Source IL6 IL6 Secreted Signaling 0.1689 0.0001476192503963 Scatter Plot
Source CDH Source GDF GDF Secreted Signaling 0.1823 0.00004124496429881596 Scatter Plot
Target CDH Source GDF GDF Secreted Signaling 0.1823 0.00004124496429881596 Scatter Plot
Target CDH Target COLLAGEN COLLAGEN ECM-Receptor 0.1972 0.000008927595151263092 Scatter Plot
Target CDH Target RANKL RANKL Secreted Signaling 0.1984 0.00000783785988913419 Scatter Plot
Target CDH Target SPP1 SPP1 Secreted Signaling 0.2054 0.000003636343629658278 Scatter Plot
Target CDH Target SEMA3 SEMA3 Secreted Signaling 0.2057 0.0000035353169953780085 Scatter Plot
Target CDH Source CD1D2 CD1D2 Cell-Cell Contact 0.2133 0.00000148671553265743 Scatter Plot
Target CDH Source CCL CCL Secreted Signaling 0.2299 0.0000002015854176979677 Scatter Plot
Target CDH Target GDF GDF Secreted Signaling 0.2308 0.00000017972731305705146 Scatter Plot
Target CDH Source CD46 CD46 Cell-Cell Contact 0.2322 0.00000015192676548703969 Scatter Plot
Target CDH Source VEGF VEGF Secreted Signaling 0.2368 0.00000008383080326025523 Scatter Plot
Source CDH Source VEGF VEGF Secreted Signaling 0.2368 0.00000008383080326025523 Scatter Plot
Target CDH Source IL16 IL16 Secreted Signaling 0.2403 0.00000005297751100536284 Scatter Plot
Target CDH Target MK MK Secreted Signaling 0.2414 0.00000004609818837467959 Scatter Plot
Target CDH Source CADM CADM Cell-Cell Contact 0.2451 0.000000028239941021473564 Scatter Plot
Source CDH Source CADM CADM Cell-Cell Contact 0.2451 0.00000002823987195952392 Scatter Plot
Target CDH Target CADM CADM Cell-Cell Contact 0.2451 0.00000002823987195952392 Scatter Plot
Target CDH Source THY1 THY1 Cell-Cell Contact 0.2488 0.000000017089312757389192 Scatter Plot
Target CDH Source CXCL CXCL Secreted Signaling 0.2510 0.000000012689479612592446 Scatter Plot
Target CDH Source NT NT Secreted Signaling 0.2521 0.000000010913979318472704 Scatter Plot
Target CDH Source SEMA3 SEMA3 Secreted Signaling 0.2656 0.000000001602732561192976 Scatter Plot
Target CDH Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2661 0.0000000014906266369674498 Scatter Plot
Target CDH Target SEMA7 SEMA7 Cell-Cell Contact 0.2775 0.00000000027078299733561055 Scatter Plot
Target CDH Target NCAM NCAM Cell-Cell Contact 0.2842 0.00000000009570099271065964 Scatter Plot
Target CDH Target EPHA EPHA Cell-Cell Contact 0.2906 0.000000000034427109751367974 Scatter Plot
Target CDH Source ANGPTL ANGPTL Secreted Signaling 0.2921 0.000000000027291875846135156 Scatter Plot
Source CDH Source CD45 CD45 Cell-Cell Contact 0.2946 0.000000000018021539197535848 Scatter Plot
Target CDH Source CD45 CD45 Cell-Cell Contact 0.2946 0.000000000018021539197535848 Scatter Plot
Target CDH Target CSPG4 CSPG4 Cell-Cell Contact 0.2948 0.000000000017446174886472376 Scatter Plot
Target CDH Target ACTIVIN ACTIVIN Secreted Signaling 0.3035 0.000000000004101756625196289 Scatter Plot
Target CDH Source CD39 CD39 Cell-Cell Contact 0.3078 0.0000000000019582433545722847 Scatter Plot
Target CDH Target ANGPTL ANGPTL Secreted Signaling 0.3081 0.0000000000018457882095332696 Scatter Plot
Target CDH Source IL2 IL2 Secreted Signaling 0.3158 0.0000000000004846415398995882 Scatter Plot
Target CDH Target AGT AGT Secreted Signaling 0.3213 0.0000000000001787991287115562 Scatter Plot
Target CDH Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.3215 0.00000000000017309461468070698 Scatter Plot
Target CDH Source CD86 CD86 Cell-Cell Contact 0.3215 0.00000000000017306948324675926 Scatter Plot
Target CDH Source ICAM ICAM Cell-Cell Contact 0.3376 0.000000000000008508021784346707 Scatter Plot
Target CDH Target THBS THBS ECM-Receptor 0.3542 0.00000000000000031525470247700553 Scatter Plot
Target CDH Target VWF VWF ECM-Receptor 0.3553 0.00000000000000025370856609130795 Scatter Plot
Target CDH Source PSAP PSAP Secreted Signaling 0.3687 0.00000000000000001500207857216858 Scatter Plot
Target CDH Source NOTCH NOTCH Cell-Cell Contact 0.3695 0.000000000000000012569185159623589 Scatter Plot
Target CDH Target BMP BMP Secreted Signaling 0.3753 0.0000000000000000035914118377066186 Scatter Plot
Target CDH Source LCK LCK Cell-Cell Contact 0.3755 0.0000000000000000034090861869223847 Scatter Plot
Target CDH Source EPHB EPHB Cell-Cell Contact 0.3825 0.0000000000000000007124909063213821 Scatter Plot
Source CDH Source EPHB EPHB Cell-Cell Contact 0.3825 0.0000000000000000007124909063213821 Scatter Plot
Source CDH Source LIGHT LIGHT Secreted Signaling 0.3834 0.0000000000000000005910020445689641 Scatter Plot
Target CDH Source LIGHT LIGHT Secreted Signaling 0.3834 0.0000000000000000005910020445689641 Scatter Plot
Target CDH Source CSF CSF Secreted Signaling 0.3835 0.0000000000000000005719944167366887 Scatter Plot
Target CDH Target SEMA6 SEMA6 Cell-Cell Contact 0.3843 0.0000000000000000004762389824504436 Scatter Plot
Target CDH Target KIT KIT Secreted Signaling 0.3873 0.00000000000000000024178692833673815 Scatter Plot
Source CDH Source RANKL RANKL Secreted Signaling 0.3941 0.00000000000000000004942000567764277 Scatter Plot
Target CDH Source RANKL RANKL Secreted Signaling 0.3941 0.00000000000000000004942000567764277 Scatter Plot
Source CDH Source LAMININ LAMININ ECM-Receptor 0.3994 0.000000000000000000014033645830429002 Scatter Plot
Target CDH Source LAMININ LAMININ ECM-Receptor 0.3994 0.000000000000000000014033645830429002 Scatter Plot
Target CDH Source LIFR LIFR Secreted Signaling 0.4030 0.000000000000000000005940909560042194 Scatter Plot
Source CDH Source LIFR LIFR Secreted Signaling 0.4030 0.000000000000000000005940909560042194 Scatter Plot
Target CDH Source CX3C CX3C Secreted Signaling 0.4060 0.000000000000000000002902313241976649 Scatter Plot
Target CDH Target CD200 CD200 Cell-Cell Contact 0.4191 0.00000000000000000000010911159725103737 Scatter Plot
Target CDH Source PROS PROS Secreted Signaling 0.4251 0.000000000000000000000022879186222185414 Scatter Plot
Target CDH Source MK MK Secreted Signaling 0.4262 0.000000000000000000000017447732144516638 Scatter Plot
Target CDH Source IGF IGF Secreted Signaling 0.4291 0.000000000000000000000008111514478516785 Scatter Plot
Target CDH Target CD39 CD39 Cell-Cell Contact 0.4410 0.00000000000000000000000033009045036404287 Scatter Plot
Target CDH Source FLT3 FLT3 Secreted Signaling 0.4453 0.00000000000000000000000010005800801094888 Scatter Plot
Target CDH Target BSP BSP ECM-Receptor 0.4516 0.000000000000000000000000016824475413283254 Scatter Plot
Target CDH Target IGF IGF Secreted Signaling 0.4565 0.00000000000000000000000000414613139966938 Scatter Plot
Target CDH Source IL7 IL7 Secreted Signaling 0.4575 0.000000000000000000000000003103364436058146 Scatter Plot
Target CDH Target DMP1 DMP1 ECM-Receptor 0.4607 0.0000000000000000000000000012207082592911272 Scatter Plot
Source CDH Source COLLAGEN COLLAGEN ECM-Receptor 0.4625 0.0000000000000000000000000007150572773285018 Scatter Plot
Target CDH Target TENASCIN TENASCIN ECM-Receptor 0.4625 0.00000000000000000000000000071336877266998645 Scatter Plot
Target CDH Target SLURP SLURP Secreted Signaling 0.4669 0.0000000000000000000000000001914709426407789 Scatter Plot
Target CDH Source PDGF PDGF Secreted Signaling 0.4676 0.00000000000000000000000000015459592994466746 Scatter Plot
Source CDH Source PDGF PDGF Secreted Signaling 0.4676 0.00000000000000000000000000015459592994466746 Scatter Plot
Target CDH Source COLLAGEN COLLAGEN ECM-Receptor 0.4724 0.000000000000000000000000000036008396427276095 Scatter Plot
Target CDH Source BST2 BST2 Cell-Cell Contact 0.4739 0.000000000000000000000000000023300463629247078 Scatter Plot
Target CDH Target FGF FGF Secreted Signaling 0.4862 0.0000000000000000000000000000004953613208821467 Scatter Plot
Target CDH Source TWEAK TWEAK Secreted Signaling 0.4912 0.0000000000000000000000000000000982954918459965 Scatter Plot
Source CDH Source TWEAK TWEAK Secreted Signaling 0.4912 0.0000000000000000000000000000000982954918459965 Scatter Plot
Target CDH Source BMP BMP Secreted Signaling 0.4977 0.000000000000000000000000000000011627354881682624 Scatter Plot
Source CDH Source BMP BMP Secreted Signaling 0.4977 0.000000000000000000000000000000011627354881682624 Scatter Plot
Target CDH Target MIF MIF Secreted Signaling 0.5024 0.0000000000000000000000000000000024066564391563725 Scatter Plot
Target CDH Source ESAM ESAM Cell-Cell Contact 0.5045 0.0000000000000000000000000000000012008540549662904 Scatter Plot
Target CDH Source GAS GAS Secreted Signaling 0.5334 0.00000000000000000000000000000000000004043832877158593 Scatter Plot
Target CDH Target CD34 CD34 Cell-Cell Contact 0.5343 0.00000000000000000000000000000000000002859671220545585 Scatter Plot
Source CDH Source ANGPT ANGPT Secreted Signaling 0.5426 0.0000000000000000000000000000000000000012328833808404689 Scatter Plot
Target CDH Source ANGPT ANGPT Secreted Signaling 0.5426 0.0000000000000000000000000000000000000012328833808404689 Scatter Plot
Target CDH Source MHC-II MHC-II Cell-Cell Contact 0.5506 0.0000000000000000000000000000000000000000551213721017887 Scatter Plot
Target CDH Source MHC-I MHC-I Cell-Cell Contact 0.5524 0.000000000000000000000000000000000000000027267004021115144 Scatter Plot
Target CDH Source SEMA7 SEMA7 Cell-Cell Contact 0.5557 0.00000000000000000000000000000000000000000709980965530484 Scatter Plot
Target CDH Target ncWNT ncWNT Secreted Signaling 0.5695 0.00000000000000000000000000000000000000000002429115973913512 Scatter Plot
Target CDH Target WNT WNT Secreted Signaling 0.6035 0.000000000000000000000000000000000000000000000000005866711828804968 Scatter Plot
Source CDH Source JAM JAM Cell-Cell Contact 0.6210 0.0000000000000000000000000000000000000000000000000000011083713385290906 Scatter Plot
Target CDH Source JAM JAM Cell-Cell Contact 0.6210 0.0000000000000000000000000000000000000000000000000000011083713385290906 Scatter Plot
Target CDH Source CD52 CD52 Cell-Cell Contact -0.4559 0.0000000000000000000000000048532694581414416 Scatter Plot
Target CDH Source TGFb TGFb Secreted Signaling -0.3920 0.0000000000000000000810449987788448 Scatter Plot
Target CDH Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.3864 0.00000000000000000029343514101468653 Scatter Plot
Source CDH Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.3864 0.00000000000000000029343514101468653 Scatter Plot
Target CDH Source SELL SELL Cell-Cell Contact -0.3486 0.0000000000000009821233081191314 Scatter Plot
Target CDH Source PARs PARs Secreted Signaling -0.3166 0.0000000000004197321190806886 Scatter Plot
Target CDH Source COMPLEMENT COMPLEMENT Secreted Signaling -0.2685 0.0000000010535660428066055 Scatter Plot
Target CDH Source CLEC CLEC Cell-Cell Contact -0.2464 0.00000002380731954489926 Scatter Plot
Target CDH Source VISTA VISTA Cell-Cell Contact -0.2371 0.00000008080540385393749 Scatter Plot
Target CDH Target CXCL CXCL Secreted Signaling -0.2360 0.00000009353218739383008 Scatter Plot
Target CDH Target CSF CSF Secreted Signaling -0.2333 0.0000001309454281813445 Scatter Plot
Target CDH Source MIF MIF Secreted Signaling -0.2294 0.00000021408056837728133 Scatter Plot
Target CDH Source SPP1 SPP1 Secreted Signaling -0.2144 0.0000013071696271260902 Scatter Plot
Source CDH Source ANGPTL ANGPTL Secreted Signaling -0.2056 0.00000355128916597829 Scatter Plot
Target CDH Source ANGPTL ANGPTL Secreted Signaling -0.2056 0.00000355128916597829 Scatter Plot
Target CDH Source SEMA4 SEMA4 Cell-Cell Contact -0.2047 0.000003917204227917826 Scatter Plot
Target CDH Source CCL CCL Secreted Signaling -0.2027 0.000004915348240504957 Scatter Plot
Target CDH Target CEACAM CEACAM Cell-Cell Contact -0.1820 0.00004264952983349846 Scatter Plot
Target CDH Source SELPLG SELPLG Cell-Cell Contact -0.1619 0.0002770173641968 Scatter Plot
Target CDH Source IL1 IL1 Secreted Signaling -0.1495 0.0007976170074555 Scatter Plot
Target CDH Target IL17 IL17 Secreted Signaling -0.1410 0.0015747018713542 Scatter Plot
Target CDH Target COLLAGEN COLLAGEN ECM-Receptor -0.1287 0.0039467972258218 Scatter Plot
Target CDH Source ANNEXIN ANNEXIN Secreted Signaling -0.1248 0.0051852260069971 Scatter Plot
Target CDH Source NCAM NCAM Cell-Cell Contact -0.1227 0.0060294288678329 Scatter Plot
Source CDH Source NCAM NCAM Cell-Cell Contact -0.1227 0.0060294288678329 Scatter Plot
Target CDH Source NKG2D NKG2D Cell-Cell Contact -0.1140 0.0107092239064898 Scatter Plot
Target CDH Source TNF TNF Secreted Signaling -0.1123 0.0119790389698108 Scatter Plot
Target CDH Source LAIR1 LAIR1 Cell-Cell Contact -0.1045 0.0194811550238911 Scatter Plot
Target CDH Source GALECTIN GALECTIN Secreted Signaling -0.1000 0.0253524241707907 Scatter Plot
Source CDH Source GALECTIN GALECTIN Secreted Signaling -0.1000 0.0253524241707908 Scatter Plot
Target CDH Target CCL CCL Secreted Signaling -0.0967 0.0307079080937089 Scatter Plot
Source CDH Source THBS THBS ECM-Receptor 0.1273 0.0043636617340766 Scatter Plot
Source CDH Source ICOS ICOS Cell-Cell Contact 0.1278 0.0041996478336564 Scatter Plot
Source CDH Source VCAM VCAM Cell-Cell Contact 0.1414 0.0015218320088133 Scatter Plot
Source CDH Target GAS GAS Secreted Signaling 0.1448 0.0011686948546592 Scatter Plot
Source CDH Target NOTCH NOTCH Cell-Cell Contact 0.1469 0.000987632853654 Scatter Plot
Source CDH Source GP1BA GP1BA Cell-Cell Contact 0.1645 0.0002195219666725 Scatter Plot
Source CDH Target FN1 FN1 ECM-Receptor 0.1664 0.000186095741024 Scatter Plot
Target CDH Target VEGF VEGF Secreted Signaling 0.1829 0.00003882596069968968 Scatter Plot
Source CDH Target VEGF VEGF Secreted Signaling 0.1829 0.00003882596069968968 Scatter Plot
Target CDH Target THY1 THY1 Cell-Cell Contact 0.1924 0.00001475998423604072 Scatter Plot
Source CDH Target THY1 THY1 Cell-Cell Contact 0.1924 0.00001475998423604072 Scatter Plot
Source CDH Target RANKL RANKL Secreted Signaling 0.1984 0.00000783785988913419 Scatter Plot
Source CDH Target OSM OSM Secreted Signaling 0.1988 0.000007458373995318854 Scatter Plot
Target CDH Target OSM OSM Secreted Signaling 0.1988 0.000007458373995318854 Scatter Plot
Source CDH Target SPP1 SPP1 Secreted Signaling 0.2054 0.000003636343629658278 Scatter Plot
Source CDH Target SEMA3 SEMA3 Secreted Signaling 0.2057 0.0000035353169953780085 Scatter Plot
Source CDH Target COLLAGEN COLLAGEN ECM-Receptor 0.2057 0.000003504171976987488 Scatter Plot
Target CDH Target COLLAGEN COLLAGEN ECM-Receptor 0.2124 0.0000016508941606326342 Scatter Plot
Source CDH Source CD1D2 CD1D2 Cell-Cell Contact 0.2133 0.00000148671553265743 Scatter Plot
Target CDH Target CD23 CD23 Cell-Cell Contact 0.2147 0.0000012593003705235591 Scatter Plot
Source CDH Target CD23 CD23 Cell-Cell Contact 0.2147 0.0000012593003705235591 Scatter Plot
Target CDH Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2307 0.0000001828371062236618 Scatter Plot
Source CDH Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2307 0.0000001828371062236618 Scatter Plot
Source CDH Target GDF GDF Secreted Signaling 0.2308 0.00000017972731305705146 Scatter Plot
Source CDH Target NODAL NODAL Secreted Signaling 0.2315 0.00000016581395936528056 Scatter Plot
Target CDH Target NODAL NODAL Secreted Signaling 0.2315 0.00000016581395936528056 Scatter Plot
Source CDH Source CD46 CD46 Cell-Cell Contact 0.2322 0.00000015192676548703969 Scatter Plot
Source CDH Source IL16 IL16 Secreted Signaling 0.2403 0.00000005297751100536284 Scatter Plot
Source CDH Target MK MK Secreted Signaling 0.2414 0.00000004609818837467959 Scatter Plot
Source CDH Source CADM CADM Cell-Cell Contact 0.2451 0.000000028239964042159584 Scatter Plot
Target CDH Target CADM CADM Cell-Cell Contact 0.2451 0.000000028239964042159584 Scatter Plot
Source CDH Target CADM CADM Cell-Cell Contact 0.2451 0.000000028239941021473564 Scatter Plot
Source CDH Source THY1 THY1 Cell-Cell Contact 0.2488 0.000000017089312757389192 Scatter Plot
Source CDH Source NT NT Secreted Signaling 0.2521 0.000000010913979318472704 Scatter Plot
Source CDH Source CCL CCL Secreted Signaling 0.2589 0.000000004204069481255524 Scatter Plot
Source CDH Source SEMA3 SEMA3 Secreted Signaling 0.2656 0.000000001602732561192976 Scatter Plot
Source CDH Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2661 0.000000001490626636967461 Scatter Plot
Source CDH Source CXCL CXCL Secreted Signaling 0.2745 0.00000000043100486536756957 Scatter Plot
Target CDH Target PTN PTN Secreted Signaling 0.2774 0.00000000027443373836338616 Scatter Plot
Source CDH Target PTN PTN Secreted Signaling 0.2774 0.00000000027443373836338616 Scatter Plot
Source CDH Target SEMA7 SEMA7 Cell-Cell Contact 0.2775 0.00000000027078299733561055 Scatter Plot
Source CDH Target NCAM NCAM Cell-Cell Contact 0.2842 0.00000000009570099271065964 Scatter Plot
Source CDH Target EPHA EPHA Cell-Cell Contact 0.2906 0.000000000034427109751367974 Scatter Plot
Source CDH Source ANGPTL ANGPTL Secreted Signaling 0.2921 0.000000000027291875846135156 Scatter Plot
Target CDH Target CD22 CD22 Cell-Cell Contact 0.2946 0.000000000018021539197535848 Scatter Plot
Source CDH Target CD22 CD22 Cell-Cell Contact 0.2946 0.000000000018021539197535848 Scatter Plot
Source CDH Source CD45 CD45 Cell-Cell Contact 0.2946 0.000000000018021539197535848 Scatter Plot
Source CDH Target CSPG4 CSPG4 Cell-Cell Contact 0.2956 0.000000000015222521745222153 Scatter Plot
Target CDH Target CSPG4 CSPG4 Cell-Cell Contact 0.2960 0.000000000014306012264551326 Scatter Plot
Source CDH Target ACTIVIN ACTIVIN Secreted Signaling 0.3035 0.000000000004101756625196289 Scatter Plot
Source CDH Source CD39 CD39 Cell-Cell Contact 0.3078 0.0000000000019582433545722847 Scatter Plot
Source CDH Target ANGPTL ANGPTL Secreted Signaling 0.3081 0.0000000000018457882095332696 Scatter Plot
Target CDH Target IL6 IL6 Secreted Signaling 0.3152 0.0000000000005416088460468336 Scatter Plot
Source CDH Target IL6 IL6 Secreted Signaling 0.3152 0.0000000000005416088460468336 Scatter Plot
Source CDH Source IL2 IL2 Secreted Signaling 0.3158 0.0000000000004846415398995882 Scatter Plot
Source CDH Target LAMININ LAMININ ECM-Receptor 0.3170 0.00000000000039084349206478083 Scatter Plot
Target CDH Target LAMININ LAMININ ECM-Receptor 0.3170 0.00000000000039084349206478083 Scatter Plot
Source CDH Target AGT AGT Secreted Signaling 0.3213 0.0000000000001787991287115562 Scatter Plot
Source CDH Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.3215 0.00000000000017309461468070882 Scatter Plot
Source CDH Source CD86 CD86 Cell-Cell Contact 0.3215 0.00000000000017306948324675926 Scatter Plot
Source CDH Source ICAM ICAM Cell-Cell Contact 0.3376 0.000000000000008508021784346707 Scatter Plot
Source CDH Target VISFATIN VISFATIN Secreted Signaling 0.3378 0.000000000000008265743728248262 Scatter Plot
Target CDH Target VISFATIN VISFATIN Secreted Signaling 0.3378 0.000000000000008265743728248262 Scatter Plot
Target CDH Target SEMA5 SEMA5 Cell-Cell Contact 0.3385 0.000000000000007112035967628069 Scatter Plot
Source CDH Target SEMA5 SEMA5 Cell-Cell Contact 0.3385 0.000000000000007112035967628069 Scatter Plot
Source CDH Target ANGPT ANGPT Secreted Signaling 0.3525 0.0000000000000004481653922380513 Scatter Plot
Target CDH Target ANGPT ANGPT Secreted Signaling 0.3525 0.0000000000000004481653922380513 Scatter Plot
Source CDH Target THBS THBS ECM-Receptor 0.3542 0.00000000000000031525470247700553 Scatter Plot
Source CDH Target VWF VWF ECM-Receptor 0.3553 0.00000000000000025370856609130795 Scatter Plot
Source CDH Target VTN VTN ECM-Receptor 0.3673 0.00000000000000002037515318448849 Scatter Plot
Target CDH Target VTN VTN ECM-Receptor 0.3673 0.00000000000000002037515318448849 Scatter Plot
Source CDH Source PSAP PSAP Secreted Signaling 0.3687 0.00000000000000001500207857216858 Scatter Plot
Source CDH Source NOTCH NOTCH Cell-Cell Contact 0.3695 0.000000000000000012569185159623589 Scatter Plot
Source CDH Target PARs PARs Secreted Signaling 0.3705 0.000000000000000010132600519100817 Scatter Plot
Target CDH Target PARs PARs Secreted Signaling 0.3705 0.000000000000000010132600519100817 Scatter Plot
Source CDH Target BMP BMP Secreted Signaling 0.3753 0.0000000000000000035914118377066186 Scatter Plot
Source CDH Source LCK LCK Cell-Cell Contact 0.3755 0.0000000000000000034090861869223847 Scatter Plot
Source CDH Source CSF CSF Secreted Signaling 0.3835 0.0000000000000000005719944167366887 Scatter Plot
Source CDH Target SEMA6 SEMA6 Cell-Cell Contact 0.3843 0.0000000000000000004762389824504436 Scatter Plot
Source CDH Target KIT KIT Secreted Signaling 0.3873 0.00000000000000000024178692833673815 Scatter Plot
Source CDH Target BAFF BAFF Secreted Signaling 0.4012 0.000000000000000000009199352999753464 Scatter Plot
Target CDH Target BAFF BAFF Secreted Signaling 0.4012 0.000000000000000000009199352999753464 Scatter Plot
Source CDH Target SEMA4 SEMA4 Cell-Cell Contact 0.4055 0.0000000000000000000032602965547934017 Scatter Plot
Target CDH Target SEMA4 SEMA4 Cell-Cell Contact 0.4055 0.0000000000000000000032602965547934017 Scatter Plot
Source CDH Source CX3C CX3C Secreted Signaling 0.4060 0.000000000000000000002902313241976649 Scatter Plot
Target CDH Target TGFb TGFb Secreted Signaling 0.4148 0.00000000000000000000032549974644649145 Scatter Plot
Source CDH Target TGFb TGFb Secreted Signaling 0.4148 0.00000000000000000000032549974644649145 Scatter Plot
Source CDH Target CD200 CD200 Cell-Cell Contact 0.4193 0.00000000000000000000010293106245977742 Scatter Plot
Target CDH Target CD200 CD200 Cell-Cell Contact 0.4197 0.00000000000000000000009391254998290251 Scatter Plot
Source CDH Target NPR2 NPR2 Secreted Signaling 0.4236 0.0000000000000000000000340335345865902 Scatter Plot
Target CDH Target NPR2 NPR2 Secreted Signaling 0.4236 0.0000000000000000000000340335345865902 Scatter Plot
Source CDH Source PROS PROS Secreted Signaling 0.4251 0.000000000000000000000022879186222185414 Scatter Plot
Source CDH Source MK MK Secreted Signaling 0.4262 0.000000000000000000000017447732144516638 Scatter Plot
Source CDH Source IGF IGF Secreted Signaling 0.4291 0.000000000000000000000008111514478516785 Scatter Plot
Source CDH Target NRG NRG Secreted Signaling 0.4399 0.0000000000000000000000004374300722112716 Scatter Plot
Target CDH Target NRG NRG Secreted Signaling 0.4399 0.0000000000000000000000004374300722112716 Scatter Plot
Source CDH Target CD39 CD39 Cell-Cell Contact 0.4410 0.00000000000000000000000033009045036404287 Scatter Plot
Target CDH Target CD39 CD39 Cell-Cell Contact 0.4410 0.00000000000000000000000033009045036404287 Scatter Plot
Source CDH Source FLT3 FLT3 Secreted Signaling 0.4453 0.00000000000000000000000010005800801094888 Scatter Plot
Target CDH Target PERIOSTIN PERIOSTIN Secreted Signaling 0.4491 0.000000000000000000000000034274452983993644 Scatter Plot
Source CDH Target PERIOSTIN PERIOSTIN Secreted Signaling 0.4491 0.000000000000000000000000034274452983993644 Scatter Plot
Source CDH Target APP APP Cell-Cell Contact 0.4506 0.00000000000000000000000002243932549519413 Scatter Plot
Target CDH Target APP APP Cell-Cell Contact 0.4506 0.00000000000000000000000002243932549519381 Scatter Plot
Source CDH Target BSP BSP ECM-Receptor 0.4516 0.000000000000000000000000016824475413283254 Scatter Plot
Source CDH Target IGF IGF Secreted Signaling 0.4565 0.00000000000000000000000000414613139966938 Scatter Plot
Source CDH Source IL7 IL7 Secreted Signaling 0.4575 0.000000000000000000000000003103364436058146 Scatter Plot
Source CDH Target DMP1 DMP1 ECM-Receptor 0.4607 0.0000000000000000000000000012207082592911272 Scatter Plot
Source CDH Target TENASCIN TENASCIN ECM-Receptor 0.4625 0.00000000000000000000000000071336877266998645 Scatter Plot
Source CDH Target SLURP SLURP Secreted Signaling 0.4669 0.0000000000000000000000000001914709426407789 Scatter Plot
Source CDH Target EPHB EPHB Cell-Cell Contact 0.4702 0.00000000000000000000000000007104989766469551 Scatter Plot
Target CDH Target EPHB EPHB Cell-Cell Contact 0.4702 0.00000000000000000000000000007104989766469551 Scatter Plot
Source CDH Source BST2 BST2 Cell-Cell Contact 0.4739 0.000000000000000000000000000023300463629247078 Scatter Plot
Source CDH Source COLLAGEN COLLAGEN ECM-Receptor 0.4749 0.000000000000000000000000000017179388199838317 Scatter Plot
Source CDH Target FGF FGF Secreted Signaling 0.4862 0.0000000000000000000000000000004953613208821467 Scatter Plot
Source CDH Target MIF MIF Secreted Signaling 0.5024 0.0000000000000000000000000000000024066564391563725 Scatter Plot
Target CDH Target ESAM ESAM Cell-Cell Contact 0.5045 0.0000000000000000000000000000000012008540549662904 Scatter Plot
Source CDH Target ESAM ESAM Cell-Cell Contact 0.5045 0.0000000000000000000000000000000012008540549662904 Scatter Plot
Source CDH Source ESAM ESAM Cell-Cell Contact 0.5045 0.0000000000000000000000000000000012008540549662904 Scatter Plot
Source CDH Source GAS GAS Secreted Signaling 0.5334 0.00000000000000000000000000000000000004043832877158593 Scatter Plot
Source CDH Target CD34 CD34 Cell-Cell Contact 0.5343 0.00000000000000000000000000000000000002859671220545708 Scatter Plot
Target CDH Target CD34 CD34 Cell-Cell Contact 0.5343 0.00000000000000000000000000000000000002859671220545708 Scatter Plot
Source CDH Source MHC-II MHC-II Cell-Cell Contact 0.5506 0.0000000000000000000000000000000000000000551213721017887 Scatter Plot
Source CDH Source MHC-I MHC-I Cell-Cell Contact 0.5524 0.000000000000000000000000000000000000000027267004021115144 Scatter Plot
Source CDH Source SEMA7 SEMA7 Cell-Cell Contact 0.5557 0.000000000000000000000000000000000000000007099809655305144 Scatter Plot
Source CDH Target ncWNT ncWNT Secreted Signaling 0.5695 0.00000000000000000000000000000000000000000002429115973913512 Scatter Plot
Source CDH Target JAM JAM Cell-Cell Contact 0.5804 0.00000000000000000000000000000000000000000000021997868905490907 Scatter Plot
Target CDH Target JAM JAM Cell-Cell Contact 0.5804 0.00000000000000000000000000000000000000000000021997868905490907 Scatter Plot
Source CDH Target WNT WNT Secreted Signaling 0.6035 0.000000000000000000000000000000000000000000000000005866711828804968 Scatter Plot
Source CDH Source CD52 CD52 Cell-Cell Contact -0.4559 0.0000000000000000000000000048532694581415104 Scatter Plot
Source CDH Source TGFb TGFb Secreted Signaling -0.3920 0.0000000000000000000810449987788448 Scatter Plot
Target CDH Target ICAM ICAM Cell-Cell Contact -0.3702 0.000000000000000010996410991204879 Scatter Plot
Source CDH Target ICAM ICAM Cell-Cell Contact -0.3702 0.00000000000000001099641099120512 Scatter Plot
Source CDH Source SELL SELL Cell-Cell Contact -0.3486 0.0000000000000009821233081191314 Scatter Plot
Target CDH Target CD52 CD52 Cell-Cell Contact -0.3384 0.000000000000007354398811827556 Scatter Plot
Source CDH Target CD52 CD52 Cell-Cell Contact -0.3384 0.000000000000007354398811827556 Scatter Plot
Source CDH Source PARs PARs Secreted Signaling -0.3166 0.0000000000004197321190806886 Scatter Plot
Source CDH Source COMPLEMENT COMPLEMENT Secreted Signaling -0.2685 0.0000000010535660428066055 Scatter Plot
Target CDH Target IFN-II IFN-II Secreted Signaling -0.2486 0.000000017561840586360937 Scatter Plot
Source CDH Target IFN-II IFN-II Secreted Signaling -0.2486 0.000000017561840586360937 Scatter Plot
Source CDH Source CLEC CLEC Cell-Cell Contact -0.2464 0.00000002380731954489926 Scatter Plot
Source CDH Target CLEC CLEC Cell-Cell Contact -0.2412 0.000000047576529126127145 Scatter Plot
Target CDH Target CLEC CLEC Cell-Cell Contact -0.2412 0.000000047576529126127145 Scatter Plot
Source CDH Source VISTA VISTA Cell-Cell Contact -0.2371 0.00000008080540385393749 Scatter Plot
Target CDH Target CSF CSF Secreted Signaling -0.2333 0.0000001309454281813445 Scatter Plot
Source CDH Target CSF CSF Secreted Signaling -0.2333 0.0000001309454281813445 Scatter Plot
Source CDH Target CXCL CXCL Secreted Signaling -0.2309 0.0000001770519838427973 Scatter Plot
Source CDH Source MIF MIF Secreted Signaling -0.2294 0.00000021408056837728133 Scatter Plot
Source CDH Source SPP1 SPP1 Secreted Signaling -0.2144 0.0000013071696271260902 Scatter Plot
Target CDH Target CXCL CXCL Secreted Signaling -0.2135 0.0000014449008750195085 Scatter Plot
Source CDH Source SEMA4 SEMA4 Cell-Cell Contact -0.2047 0.000003917204227917826 Scatter Plot
Source CDH Source CCL CCL Secreted Signaling -0.2027 0.000004915348240504957 Scatter Plot
Target CDH Target CCL CCL Secreted Signaling -0.2023 0.000005115703501742956 Scatter Plot
Source CDH Target CCL CCL Secreted Signaling -0.2008 0.000006029039036317712 Scatter Plot
Target CDH Target CEACAM CEACAM Cell-Cell Contact -0.1820 0.00004264952983349823 Scatter Plot
Source CDH Target CEACAM CEACAM Cell-Cell Contact -0.1820 0.00004264952983349846 Scatter Plot
Source CDH Target VCAM VCAM Cell-Cell Contact -0.1816 0.00004426211949557312 Scatter Plot
Target CDH Target VCAM VCAM Cell-Cell Contact -0.1816 0.00004426211949557312 Scatter Plot
Source CDH Source SELPLG SELPLG Cell-Cell Contact -0.1619 0.0002770173641968 Scatter Plot
Source CDH Source IL1 IL1 Secreted Signaling -0.1495 0.0007976170074555 Scatter Plot
Source CDH Target IL17 IL17 Secreted Signaling -0.1410 0.0015747018713542 Scatter Plot
Target CDH Target COLLAGEN COLLAGEN ECM-Receptor -0.1362 0.0022678798204446 Scatter Plot
Source CDH Target COLLAGEN COLLAGEN ECM-Receptor -0.1306 0.0034448751558615 Scatter Plot
Source CDH Source ANNEXIN ANNEXIN Secreted Signaling -0.1248 0.0051852260069971 Scatter Plot
Source CDH Target GRN GRN Secreted Signaling -0.1187 0.0079080865150549 Scatter Plot
Target CDH Target GRN GRN Secreted Signaling -0.1187 0.0079080865150549 Scatter Plot
Source CDH Source NKG2D NKG2D Cell-Cell Contact -0.1140 0.0107092239064898 Scatter Plot
Source CDH Source TNF TNF Secreted Signaling -0.1123 0.0119790389698108 Scatter Plot
Source CDH Target VEGF VEGF Secreted Signaling -0.1111 0.0129340325340596 Scatter Plot
Target CDH Target VEGF VEGF Secreted Signaling -0.1111 0.0129340325340596 Scatter Plot
Source CDH Source LAIR1 LAIR1 Cell-Cell Contact -0.1045 0.0194811550238911 Scatter Plot
Source CDH Target BST2 BST2 Cell-Cell Contact -0.1043 0.0196697290112374 Scatter Plot
Target CDH Target BST2 BST2 Cell-Cell Contact -0.1043 0.0196697290112374 Scatter Plot
Source CDH Target LAIR1 LAIR1 Cell-Cell Contact -0.1043 0.0196697290112374 Scatter Plot
Target CDH Target LAIR1 LAIR1 Cell-Cell Contact -0.1043 0.0196697290112374 Scatter Plot

Cells that are targets of CDH from HSCs*

Cells that are source of CDH to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.