Pathway: ICAM

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Cell-Cell Contact

Details on the ICAM pathway:

Specificity Index HSPC as target: 0.578
HSPC as source: 0.597

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the ICAM pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Source ICAM Source PECAM1 PECAM1 Cell-Cell Contact 0.0965 0.0308896488011611 Scatter Plot
Source ICAM Source SEMA6 SEMA6 Cell-Cell Contact 0.1012 0.0236983686859051 Scatter Plot
Source ICAM Source IL6 IL6 Secreted Signaling 0.1157 0.0096298282683008 Scatter Plot
Target ICAM Source IL1 IL1 Secreted Signaling 0.1179 0.0083049556041797 Scatter Plot
Target ICAM Target ANGPTL ANGPTL Secreted Signaling 0.1203 0.0070720334710291 Scatter Plot
Source ICAM Source WNT WNT Secreted Signaling 0.1255 0.0049557978004261 Scatter Plot
Source ICAM Source FGF FGF Secreted Signaling 0.1292 0.0038123848949218 Scatter Plot
Source ICAM Source PTN PTN Secreted Signaling 0.1313 0.0032557468686404 Scatter Plot
Source ICAM Source ncWNT ncWNT Secreted Signaling 0.1350 0.0024804009829868 Scatter Plot
Source ICAM Source OSM OSM Secreted Signaling 0.1371 0.0021250139484627 Scatter Plot
Source ICAM Source SELPLG SELPLG Cell-Cell Contact 0.1381 0.0019653108687175 Scatter Plot
Source ICAM Source SEMA3 SEMA3 Secreted Signaling 0.1427 0.0013828798157524 Scatter Plot
Target ICAM Source NKG2D NKG2D Cell-Cell Contact 0.1484 0.0008729633535437 Scatter Plot
Source ICAM Source TGFb TGFb Secreted Signaling 0.1538 0.000559831617583 Scatter Plot
Target ICAM Target VEGF VEGF Secreted Signaling 0.1596 0.000338712752065 Scatter Plot
Target ICAM Source TGFb TGFb Secreted Signaling 0.1646 0.0002190316817484 Scatter Plot
Source ICAM Source IL2 IL2 Secreted Signaling 0.1752 0.00008167996600101376 Scatter Plot
Target ICAM Target SELE SELE Cell-Cell Contact 0.1788 0.00005808641476652036 Scatter Plot
Target ICAM Target IL17 IL17 Secreted Signaling 0.1819 0.00004268092501934196 Scatter Plot
Source ICAM Source NT NT Secreted Signaling 0.1883 0.00002250036809100562 Scatter Plot
Source ICAM Source VEGF VEGF Secreted Signaling 0.2096 0.000002274665319673383 Scatter Plot
Source ICAM Source RANKL RANKL Secreted Signaling 0.2096 0.0000022733305773713348 Scatter Plot
Source ICAM Source THY1 THY1 Cell-Cell Contact 0.2106 0.0000020316621829517425 Scatter Plot
Source ICAM Source GALECTIN GALECTIN Secreted Signaling 0.2126 0.000001618616410022571 Scatter Plot
Source ICAM Source APELIN APELIN Secreted Signaling 0.2129 0.000001560669408002614 Scatter Plot
Source ICAM Source CADM CADM Cell-Cell Contact 0.2215 0.0000005653286331392954 Scatter Plot
Source ICAM Source IGF IGF Secreted Signaling 0.2216 0.0000005563035535590052 Scatter Plot
Source ICAM Source CD46 CD46 Cell-Cell Contact 0.2224 0.0000005084383031063249 Scatter Plot
Source ICAM Source CD1D2 CD1D2 Cell-Cell Contact 0.2258 0.0000003366565484055949 Scatter Plot
Source ICAM Source GDF GDF Secreted Signaling 0.2283 0.0000002462917668220419 Scatter Plot
Source ICAM Source CD39 CD39 Cell-Cell Contact 0.2290 0.00000022447671554389458 Scatter Plot
Target ICAM Source BAFF BAFF Secreted Signaling 0.2347 0.00000011049073701988523 Scatter Plot
Source ICAM Source EPHB EPHB Cell-Cell Contact 0.2418 0.000000043781360279796994 Scatter Plot
Target ICAM Target IL1 IL1 Secreted Signaling 0.2423 0.0000000408069717517871 Scatter Plot
Target ICAM Source SELPLG SELPLG Cell-Cell Contact 0.2433 0.000000035813518741852536 Scatter Plot
Source ICAM Source NOTCH NOTCH Cell-Cell Contact 0.2529 0.000000009741652858439709 Scatter Plot
Source ICAM Source CSF CSF Secreted Signaling 0.2541 0.000000008289898553814431 Scatter Plot
Source ICAM Source FLT3 FLT3 Secreted Signaling 0.2706 0.0000000007689842409033944 Scatter Plot
Source ICAM Source LIGHT LIGHT Secreted Signaling 0.2714 0.0000000006818714573269321 Scatter Plot
Target ICAM Source SPP1 SPP1 Secreted Signaling 0.2805 0.000000000169903165588285 Scatter Plot
Target ICAM Source CCL CCL Secreted Signaling 0.2812 0.00000000015375979147288415 Scatter Plot
Source ICAM Source CD34 CD34 Cell-Cell Contact 0.2861 0.00000000007089455124118865 Scatter Plot
Source ICAM Source MK MK Secreted Signaling 0.2946 0.000000000018192348328339294 Scatter Plot
Target ICAM Source LAIR1 LAIR1 Cell-Cell Contact 0.2959 0.000000000014509133719068467 Scatter Plot
Target ICAM Source APP APP Cell-Cell Contact 0.2992 0.000000000008449748827063128 Scatter Plot
Source ICAM Source CX3C CX3C Secreted Signaling 0.2998 0.000000000007667054953638325 Scatter Plot
Target ICAM Source NCAM NCAM Cell-Cell Contact 0.3077 0.0000000000019835495900164435 Scatter Plot
Source ICAM Source PDGF PDGF Secreted Signaling 0.3077 0.0000000000019816587391091364 Scatter Plot
Source ICAM Source VCAM VCAM Cell-Cell Contact 0.3082 0.000000000001837585734091693 Scatter Plot
Target ICAM Source GRN GRN Secreted Signaling 0.3084 0.0000000000017597673653752436 Scatter Plot
Source ICAM Source CCL CCL Secreted Signaling 0.3127 0.0000000000008342453047834348 Scatter Plot
Target ICAM Source TNF TNF Secreted Signaling 0.3143 0.000000000000627532223659081 Scatter Plot
Source ICAM Source SEMA7 SEMA7 Cell-Cell Contact 0.3308 0.000000000000031327227882451456 Scatter Plot
Target ICAM Source CLEC CLEC Cell-Cell Contact 0.3354 0.000000000000012940930223008716 Scatter Plot
Source ICAM Source CDH CDH Cell-Cell Contact 0.3376 0.000000000000008508021784346707 Scatter Plot
Source ICAM Source PROS PROS Secreted Signaling 0.3420 0.000000000000003624178709089065 Scatter Plot
Source ICAM Source LIFR LIFR Secreted Signaling 0.3459 0.0000000000000016710438342461913 Scatter Plot
Source ICAM Source LAMININ LAMININ ECM-Receptor 0.3598 0.00000000000000009847614248254541 Scatter Plot
Source ICAM Source CD45 CD45 Cell-Cell Contact 0.3641 0.00000000000000003987186883640754 Scatter Plot
Source ICAM Source IL16 IL16 Secreted Signaling 0.3801 0.00000000000000000124415666494055 Scatter Plot
Target ICAM Source PARs PARs Secreted Signaling 0.3925 0.00000000000000000007217692906561645 Scatter Plot
Target ICAM Target IFN-II IFN-II Secreted Signaling 0.3988 0.000000000000000000016544375099523598 Scatter Plot
Source ICAM Source BMP BMP Secreted Signaling 0.3992 0.000000000000000000014999958073360105 Scatter Plot
Source ICAM Source TWEAK TWEAK Secreted Signaling 0.4052 0.000000000000000000003509441854017199 Scatter Plot
Target ICAM Target CCL CCL Secreted Signaling 0.4074 0.0000000000000000000020379497399095976 Scatter Plot
Source ICAM Source IL7 IL7 Secreted Signaling 0.4081 0.0000000000000000000017164773876132515 Scatter Plot
Source ICAM Source ESAM ESAM Cell-Cell Contact 0.4123 0.0000000000000000000006057846065630438 Scatter Plot
Source ICAM Source COLLAGEN COLLAGEN ECM-Receptor 0.4278 0.000000000000000000000011375106588886245 Scatter Plot
Source ICAM Source BST2 BST2 Cell-Cell Contact 0.4309 0.000000000000000000000005022834214487148 Scatter Plot
Source ICAM Source GAS GAS Secreted Signaling 0.4406 0.00000000000000000000000036632270234806047 Scatter Plot
Target ICAM Source ANNEXIN ANNEXIN Secreted Signaling 0.4477 0.00000000000000000000000005104565641347698 Scatter Plot
Source ICAM Source JAM JAM Cell-Cell Contact 0.4557 0.000000000000000000000000005139272327229664 Scatter Plot
Target ICAM Source VISTA VISTA Cell-Cell Contact 0.4603 0.0000000000000000000000000013734514268081062 Scatter Plot
Source ICAM Source ANGPT ANGPT Secreted Signaling 0.4784 0.0000000000000000000000000000057046686509279945 Scatter Plot
Source ICAM Source PSAP PSAP Secreted Signaling 0.4849 0.0000000000000000000000000000007372244058590847 Scatter Plot
Target ICAM Source SELL SELL Cell-Cell Contact 0.4985 0.00000000000000000000000000000000882435140402408 Scatter Plot
Source ICAM Source MHC-I MHC-I Cell-Cell Contact 0.5059 0.0000000000000000000000000000000007387697812736614 Scatter Plot
Target ICAM Source SEMA4 SEMA4 Cell-Cell Contact 0.5136 0.00000000000000000000000000000000005216226674781004 Scatter Plot
Source ICAM Source MHC-II MHC-II Cell-Cell Contact 0.5663 0.00000000000000000000000000000000000000000009340850275978002 Scatter Plot
Target ICAM Source COMPLEMENT COMPLEMENT Secreted Signaling 0.5979 0.00000000000000000000000000000000000000000000000008224644731430754 Scatter Plot
Target ICAM Source CD52 CD52 Cell-Cell Contact 0.6453 0.0000000000000000000000000000000000000000000000000000000000029608772396084404 Scatter Plot
Target ICAM Target CD34 CD34 Cell-Cell Contact -0.5339 0.00000000000000000000000000000000000003329761553733533 Scatter Plot
Target ICAM Source MHC-I MHC-I Cell-Cell Contact -0.5280 0.000000000000000000000000000000000000297002947272062 Scatter Plot
Target ICAM Source JAM JAM Cell-Cell Contact -0.5208 0.000000000000000000000000000000000004051600388556471 Scatter Plot
Target ICAM Target ESAM ESAM Cell-Cell Contact -0.4960 0.000000000000000000000000000000020632325621127456 Scatter Plot
Target ICAM Source ESAM ESAM Cell-Cell Contact -0.4960 0.000000000000000000000000000000020632325621127456 Scatter Plot
Target ICAM Source BST2 BST2 Cell-Cell Contact -0.4826 0.0000000000000000000000000000015380186260431816 Scatter Plot
Target ICAM Source ANGPT ANGPT Secreted Signaling -0.4667 0.0000000000000000000000000002020915950689146 Scatter Plot
Target ICAM Source BMP BMP Secreted Signaling -0.4644 0.0000000000000000000000000004066354071013954 Scatter Plot
Target ICAM Target PARs PARs Secreted Signaling -0.4555 0.000000000000000000000000005433859410425191 Scatter Plot
Target ICAM Target WNT WNT Secreted Signaling -0.4512 0.000000000000000000000000018770172587186863 Scatter Plot
Target ICAM Source PDGF PDGF Secreted Signaling -0.4370 0.0000000000000000000000009647858193434176 Scatter Plot
Target ICAM Target KIT KIT Secreted Signaling -0.4365 0.0000000000000000000000011050921945988239 Scatter Plot
Target ICAM Target MK MK Secreted Signaling -0.4325 0.000000000000000000000003236836975450003 Scatter Plot
Target ICAM Target FGF FGF Secreted Signaling -0.4323 0.0000000000000000000000034271802313323985 Scatter Plot
Target ICAM Target ncWNT ncWNT Secreted Signaling -0.4261 0.00000000000000000000001786787658429689 Scatter Plot
Target ICAM Source COLLAGEN COLLAGEN ECM-Receptor -0.4258 0.000000000000000000000018961320301241598 Scatter Plot
Target ICAM Source LIFR LIFR Secreted Signaling -0.4255 0.00000000000000000000002086468219746246 Scatter Plot
Target ICAM Source MHC-II MHC-II Cell-Cell Contact -0.4202 0.00000000000000000000008161216510278765 Scatter Plot
Target ICAM Target CD39 CD39 Cell-Cell Contact -0.4185 0.00000000000000000000012797378309874412 Scatter Plot
Target ICAM Source TWEAK TWEAK Secreted Signaling -0.4094 0.0000000000000000000012541175439999121 Scatter Plot
Target ICAM Target IGF IGF Secreted Signaling -0.4065 0.0000000000000000000025306652340512718 Scatter Plot
Target ICAM Target TENASCIN TENASCIN ECM-Receptor -0.4045 0.0000000000000000000041241408612377024 Scatter Plot
Target ICAM Source FLT3 FLT3 Secreted Signaling -0.4037 0.000000000000000000005078016849035088 Scatter Plot
Target ICAM Target SLURP SLURP Secreted Signaling -0.4011 0.000000000000000000009478635508433038 Scatter Plot
Target ICAM Source EPHB EPHB Cell-Cell Contact -0.3952 0.0000000000000000000386097988896049 Scatter Plot
Target ICAM Source GAS GAS Secreted Signaling -0.3946 0.000000000000000000044310784031285777 Scatter Plot
Target ICAM Source SEMA7 SEMA7 Cell-Cell Contact -0.3916 0.00000000000000000008980589768812182 Scatter Plot
Target ICAM Source LCK LCK Cell-Cell Contact -0.3915 0.0000000000000000000924094452303332 Scatter Plot
Target ICAM Target VWF VWF ECM-Receptor -0.3847 0.000000000000000000439398933336762 Scatter Plot
Target ICAM Target CDH CDH Cell-Cell Contact -0.3702 0.000000000000000010996410991204879 Scatter Plot
Target ICAM Source CDH CDH Cell-Cell Contact -0.3702 0.00000000000000001099641099120512 Scatter Plot
Target ICAM Target SEMA5 SEMA5 Cell-Cell Contact -0.3576 0.00000000000000015629624696982082 Scatter Plot
Target ICAM Source IL7 IL7 Secreted Signaling -0.3545 0.0000000000000002983183799142917 Scatter Plot
Target ICAM Target ANGPT ANGPT Secreted Signaling -0.3507 0.0000000000000006455370497438225 Scatter Plot
Target ICAM Target NPR2 NPR2 Secreted Signaling -0.3459 0.000000000000001671490710311178 Scatter Plot
Target ICAM Target VTN VTN ECM-Receptor -0.3314 0.000000000000027533109721104657 Scatter Plot
Target ICAM Target SEMA4 SEMA4 Cell-Cell Contact -0.3293 0.00000000000004092988185117336 Scatter Plot
Target ICAM Source PROS PROS Secreted Signaling -0.3283 0.00000000000004951463047102738 Scatter Plot
Target ICAM Target DMP1 DMP1 ECM-Receptor -0.3273 0.00000000000006027695365114217 Scatter Plot
Target ICAM Source MK MK Secreted Signaling -0.3211 0.00000000000018582413074104398 Scatter Plot
Target ICAM Target BSP BSP ECM-Receptor -0.3166 0.000000000000417447057765306 Scatter Plot
Target ICAM Target APP APP Cell-Cell Contact -0.3126 0.0000000000008432896490713175 Scatter Plot
Target ICAM Target SEMA6 SEMA6 Cell-Cell Contact -0.3031 0.0000000000043532256411692346 Scatter Plot
Target ICAM Target BMP BMP Secreted Signaling -0.3017 0.000000000005523102307469698 Scatter Plot
Target ICAM Target PERIOSTIN PERIOSTIN Secreted Signaling -0.2983 0.000000000009756817656209939 Scatter Plot
Target ICAM Target ANGPTL ANGPTL Secreted Signaling -0.2937 0.000000000020977196951808518 Scatter Plot
Target ICAM Target SPP1 SPP1 Secreted Signaling -0.2878 0.00000000005446047732241431 Scatter Plot
Target ICAM Source NT NT Secreted Signaling -0.2821 0.0000000001335736624575197 Scatter Plot
Target ICAM Target MIF MIF Secreted Signaling -0.2790 0.00000000021574888408846276 Scatter Plot
Target ICAM Source CX3C CX3C Secreted Signaling -0.2732 0.0000000005191725926222357 Scatter Plot
Target ICAM Source GALECTIN GALECTIN Secreted Signaling -0.2715 0.0000000006731814093332861 Scatter Plot
Source ICAM Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.2703 0.0000000007994472643508232 Scatter Plot
Target ICAM Source VEGF VEGF Secreted Signaling -0.2699 0.000000000856521652099739 Scatter Plot
Target ICAM Target CD200 CD200 Cell-Cell Contact -0.2684 0.0000000010626006080381967 Scatter Plot
Source ICAM Source SEMA4 SEMA4 Cell-Cell Contact -0.2662 0.0000000014737030990590299 Scatter Plot
Target ICAM Target THBS THBS ECM-Receptor -0.2623 0.000000002604385772454381 Scatter Plot
Target ICAM Source IL2 IL2 Secreted Signaling -0.2556 0.000000006685424289968062 Scatter Plot
Target ICAM Source RANKL RANKL Secreted Signaling -0.2546 0.000000007691212272824982 Scatter Plot
Target ICAM Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.2524 0.0000000104375214982999 Scatter Plot
Target ICAM Source IGF IGF Secreted Signaling -0.2508 0.000000012997471889301246 Scatter Plot
Target ICAM Source NOTCH NOTCH Cell-Cell Contact -0.2422 0.00000004167709826437204 Scatter Plot
Target ICAM Target VEGF VEGF Secreted Signaling -0.2404 0.00000005248629716767055 Scatter Plot
Target ICAM Source CXCL CXCL Secreted Signaling -0.2399 0.000000056284497493970734 Scatter Plot
Target ICAM Source LAMININ LAMININ ECM-Receptor -0.2342 0.00000011721084503971997 Scatter Plot
Target ICAM Source GP1BA GP1BA Cell-Cell Contact -0.2315 0.00000016596988735491716 Scatter Plot
Target ICAM Target LAMININ LAMININ ECM-Receptor -0.2300 0.00000019926741903948454 Scatter Plot
Target ICAM Target FN1 FN1 ECM-Receptor -0.2192 0.0000007456639720655814 Scatter Plot
Target ICAM Source CD46 CD46 Cell-Cell Contact -0.2169 0.0000009739682414685786 Scatter Plot
Target ICAM Source CSF CSF Secreted Signaling -0.2167 0.0000010027367818404484 Scatter Plot
Target ICAM Source VCAM VCAM Cell-Cell Contact -0.2150 0.000001221979719488215 Scatter Plot
Source ICAM Source PARs PARs Secreted Signaling -0.2107 0.000002003633124479968 Scatter Plot
Target ICAM Target CSPG4 CSPG4 Cell-Cell Contact -0.2083 0.0000026347845129367675 Scatter Plot
Target ICAM Target TGFb TGFb Secreted Signaling -0.2068 0.000003101179186580607 Scatter Plot
Target ICAM Source CD86 CD86 Cell-Cell Contact -0.2018 0.000005427753844675948 Scatter Plot
Target ICAM Target ACTIVIN ACTIVIN Secreted Signaling -0.2016 0.000005562935547016261 Scatter Plot
Source ICAM Source VISTA VISTA Cell-Cell Contact -0.1930 0.000013865890951717898 Scatter Plot
Target ICAM Source CCL CCL Secreted Signaling -0.1801 0.00005103722837974146 Scatter Plot
Source ICAM Source SELL SELL Cell-Cell Contact -0.1778 0.00006420246711345677 Scatter Plot
Source ICAM Source NCAM NCAM Cell-Cell Contact -0.1742 0.00009003491201837887 Scatter Plot
Target ICAM Source ANGPTL ANGPTL Secreted Signaling -0.1705 0.0001271743120916 Scatter Plot
Target ICAM Target CADM CADM Cell-Cell Contact -0.1686 0.0001526506519122 Scatter Plot
Target ICAM Source CADM CADM Cell-Cell Contact -0.1686 0.0001526506519122 Scatter Plot
Source ICAM Source TGFb TGFb Secreted Signaling -0.1645 0.0002202436373916 Scatter Plot
Source ICAM Source BAFF BAFF Secreted Signaling -0.1503 0.0007455662150044 Scatter Plot
Target ICAM Target EPHA EPHA Cell-Cell Contact -0.1493 0.0008112588212028 Scatter Plot
Source ICAM Source ANGPTL ANGPTL Secreted Signaling -0.1481 0.0008941296167913 Scatter Plot
Target ICAM Source PSAP PSAP Secreted Signaling -0.1466 0.0010090267194836 Scatter Plot
Target ICAM Target COLLAGEN COLLAGEN ECM-Receptor -0.1430 0.0013501557942273 Scatter Plot
Target ICAM Source CD1D2 CD1D2 Cell-Cell Contact -0.1415 0.0015188987029204 Scatter Plot
Target ICAM Source THY1 THY1 Cell-Cell Contact -0.1318 0.0031473888793131 Scatter Plot
Target ICAM Source PTN PTN Secreted Signaling -0.1296 0.0036962125414637 Scatter Plot
Target ICAM Target SEMA3 SEMA3 Secreted Signaling -0.1291 0.0038452406452549 Scatter Plot
Target ICAM Source GDF GDF Secreted Signaling -0.1287 0.0039522031128385 Scatter Plot
Target ICAM Source APELIN APELIN Secreted Signaling -0.1209 0.0068095026938231 Scatter Plot
Target ICAM Source AGRN AGRN ECM-Receptor -0.1183 0.0081036654798737 Scatter Plot
Target ICAM Source CD39 CD39 Cell-Cell Contact -0.1165 0.0091188012525027 Scatter Plot
Target ICAM Source PECAM1 PECAM1 Cell-Cell Contact -0.1137 0.010921657386826 Scatter Plot
Target ICAM Source CD45 CD45 Cell-Cell Contact -0.1126 0.0117698624413362 Scatter Plot
Source ICAM Source THBS THBS ECM-Receptor -0.1111 0.0129199926713241 Scatter Plot
Target ICAM Target GAS GAS Secreted Signaling -0.1066 0.017104166812353 Scatter Plot
Target ICAM Target IL6 IL6 Secreted Signaling -0.1034 0.0207285018917561 Scatter Plot
Target ICAM Source LIGHT LIGHT Secreted Signaling -0.1027 0.021630007492383 Scatter Plot
Target ICAM Target GDF GDF Secreted Signaling -0.0990 0.0268318319228998 Scatter Plot
Target ICAM Target RANKL RANKL Secreted Signaling -0.0978 0.0287008112012017 Scatter Plot
Target ICAM Source SEMA3 SEMA3 Secreted Signaling -0.0965 0.0309790159537762 Scatter Plot
Source ICAM Source TNF TNF Secreted Signaling -0.0963 0.0313900056694167 Scatter Plot
Source ICAM Target PECAM1 PECAM1 Cell-Cell Contact 0.0965 0.030889648801161 Scatter Plot
Target ICAM Target SPP1 SPP1 Secreted Signaling 0.1037 0.0203756404392377 Scatter Plot
Source ICAM Target TWEAK TWEAK Secreted Signaling 0.1069 0.0167625287593061 Scatter Plot
Source ICAM Target AGT AGT Secreted Signaling 0.1073 0.0164062868306455 Scatter Plot
Source ICAM Target CCL CCL Secreted Signaling 0.1093 0.0145001666701466 Scatter Plot
Target ICAM Target LAIR1 LAIR1 Cell-Cell Contact 0.1101 0.0137433232493763 Scatter Plot
Target ICAM Target BST2 BST2 Cell-Cell Contact 0.1101 0.0137433232493763 Scatter Plot
Source ICAM Target SELPLG SELPLG Cell-Cell Contact 0.1111 0.0129585110259744 Scatter Plot
Source ICAM Target GAS GAS Secreted Signaling 0.1178 0.008345515252016 Scatter Plot
Source ICAM Target PDGF PDGF Secreted Signaling 0.1190 0.0077382156699016 Scatter Plot
Target ICAM Target CD86 CD86 Cell-Cell Contact 0.1256 0.0049092078274598 Scatter Plot
Target ICAM Target GRN GRN Secreted Signaling 0.1299 0.003628467412875 Scatter Plot
Source ICAM Target SEMA3 SEMA3 Secreted Signaling 0.1342 0.0026347492325039 Scatter Plot
Source ICAM Target THY1 THY1 Cell-Cell Contact 0.1474 0.0009502017885927 Scatter Plot
Source ICAM Target VEGF VEGF Secreted Signaling 0.1561 0.0004584569236675 Scatter Plot
Source ICAM Target NOTCH NOTCH Cell-Cell Contact 0.1647 0.0002171609917385 Scatter Plot
Source ICAM Target OSM OSM Secreted Signaling 0.1671 0.0001743643570445 Scatter Plot
Source ICAM Target CD23 CD23 Cell-Cell Contact 0.1721 0.0001097475152521 Scatter Plot
Target ICAM Target GALECTIN GALECTIN Secreted Signaling 0.1741 0.00009147818027918015 Scatter Plot
Source ICAM Target RANKL RANKL Secreted Signaling 0.1746 0.0000872521515448252 Scatter Plot
Target ICAM Target SEMA3 SEMA3 Secreted Signaling 0.1791 0.00005624181653477576 Scatter Plot
Source ICAM Target EPHA EPHA Cell-Cell Contact 0.1859 0.00002880789262461138 Scatter Plot
Source ICAM Target SEMA7 SEMA7 Cell-Cell Contact 0.1874 0.00002478730308488628 Scatter Plot
Source ICAM Target GALECTIN GALECTIN Secreted Signaling 0.2044 0.00000407222292702294 Scatter Plot
Source ICAM Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.2140 0.0000013742861324979914 Scatter Plot
Source ICAM Target GDF GDF Secreted Signaling 0.2213 0.0000005762839674729807 Scatter Plot
Source ICAM Source ANGPTL ANGPTL Secreted Signaling 0.2214 0.0000005684906276704066 Scatter Plot
Source ICAM Target CADM CADM Cell-Cell Contact 0.2215 0.0000005653286331392954 Scatter Plot
Source ICAM Target COLLAGEN COLLAGEN ECM-Receptor 0.2241 0.0000004139072902459023 Scatter Plot
Source ICAM Source IGF IGF Secreted Signaling 0.2301 0.000000196535844447758 Scatter Plot
Source ICAM Target SEMA6 SEMA6 Cell-Cell Contact 0.2303 0.00000019077813629209466 Scatter Plot
Source ICAM Target SEMA5 SEMA5 Cell-Cell Contact 0.2372 0.00000007957593615787085 Scatter Plot
Target ICAM Target COLLAGEN COLLAGEN ECM-Receptor 0.2401 0.0000000548645498210934 Scatter Plot
Source ICAM Target CSPG4 CSPG4 Cell-Cell Contact 0.2405 0.00000005184351790476702 Scatter Plot
Source ICAM Target MK MK Secreted Signaling 0.2406 0.00000005100560725662384 Scatter Plot
Target ICAM Target IL1 IL1 Secreted Signaling 0.2418 0.00000004369993497799541 Scatter Plot
Source ICAM Target PTN PTN Secreted Signaling 0.2450 0.000000028525967603299223 Scatter Plot
Source ICAM Target SPP1 SPP1 Secreted Signaling 0.2497 0.000000015259236692614024 Scatter Plot
Source ICAM Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2548 0.000000007548072443952008 Scatter Plot
Source ICAM Source CXCL CXCL Secreted Signaling 0.2611 0.0000000030954790095382894 Scatter Plot
Source ICAM Target VISFATIN VISFATIN Secreted Signaling 0.2644 0.000000001913915575967576 Scatter Plot
Source ICAM Target IGF IGF Secreted Signaling 0.2688 0.000000001005566935001821 Scatter Plot
Source ICAM Target FN1 FN1 ECM-Receptor 0.2787 0.00000000022646514172849507 Scatter Plot
Target ICAM Target CSF CSF Secreted Signaling 0.2814 0.00000000014921987768968182 Scatter Plot
Source ICAM Target ANGPTL ANGPTL Secreted Signaling 0.2872 0.00000000005958468260720225 Scatter Plot
Source ICAM Target NODAL NODAL Secreted Signaling 0.2886 0.00000000004735446078771205 Scatter Plot
Source ICAM Target EPHB EPHB Cell-Cell Contact 0.2915 0.00000000002982544528954202 Scatter Plot
Source ICAM Source IL2 IL2 Secreted Signaling 0.2919 0.000000000027894092522848497 Scatter Plot
Source ICAM Target THBS THBS ECM-Receptor 0.2952 0.0000000000163651039940684 Scatter Plot
Source ICAM Target SELL SELL Cell-Cell Contact 0.2954 0.000000000015854051772701478 Scatter Plot
Source ICAM Target NPR2 NPR2 Secreted Signaling 0.2999 0.000000000007525693031264436 Scatter Plot
Source ICAM Target LAMININ LAMININ ECM-Receptor 0.3096 0.0000000000014256105854175005 Scatter Plot
Target ICAM Target CXCL CXCL Secreted Signaling 0.3138 0.0000000000006941824961061635 Scatter Plot
Target ICAM Target ANNEXIN ANNEXIN Secreted Signaling 0.3144 0.0000000000006187844511948625 Scatter Plot
Source ICAM Target PARs PARs Secreted Signaling 0.3242 0.00000000000010538081802932209 Scatter Plot
Source ICAM Source CD86 CD86 Cell-Cell Contact 0.3323 0.000000000000023523059878014442 Scatter Plot
Source ICAM Target VWF VWF ECM-Receptor 0.3329 0.000000000000020881214558807082 Scatter Plot
Source ICAM Target BMP BMP Secreted Signaling 0.3353 0.000000000000013372620160253732 Scatter Plot
Source ICAM Target CDH CDH Cell-Cell Contact 0.3376 0.000000000000008508021784346707 Scatter Plot
Source ICAM Target IL6 IL6 Secreted Signaling 0.3409 0.000000000000004508907689961777 Scatter Plot
Source ICAM Target ACTIVIN ACTIVIN Secreted Signaling 0.3490 0.000000000000000911380025761297 Scatter Plot
Source ICAM Target ANGPT ANGPT Secreted Signaling 0.3574 0.00000000000000016265019553398032 Scatter Plot
Source ICAM Target VTN VTN ECM-Receptor 0.3634 0.00000000000000004642692273013295 Scatter Plot
Source ICAM Target CD22 CD22 Cell-Cell Contact 0.3641 0.00000000000000003987186883640669 Scatter Plot
Source ICAM Target TGFb TGFb Secreted Signaling 0.3661 0.000000000000000026140150227132938 Scatter Plot
Target ICAM Target VCAM VCAM Cell-Cell Contact 0.3689 0.000000000000000014516911893364393 Scatter Plot
Source ICAM Target KIT KIT Secreted Signaling 0.3695 0.000000000000000012756875927898017 Scatter Plot
Source ICAM Target BSP BSP ECM-Receptor 0.3739 0.000000000000000004880928358744291 Scatter Plot
Target ICAM Target IFN-II IFN-II Secreted Signaling 0.3743 0.0000000000000000044929388974761535 Scatter Plot
Source ICAM Source LCK LCK Cell-Cell Contact 0.3800 0.0000000000000000012607621823666665 Scatter Plot
Source ICAM Source IL16 IL16 Secreted Signaling 0.3801 0.0000000000000000012441566649405772 Scatter Plot
Source ICAM Target PERIOSTIN PERIOSTIN Secreted Signaling 0.3827 0.0000000000000000006858874071499632 Scatter Plot
Source ICAM Target DMP1 DMP1 ECM-Receptor 0.3860 0.000000000000000000322306248477064 Scatter Plot
Source ICAM Target NRG NRG Secreted Signaling 0.3938 0.00000000000000000005292890528157144 Scatter Plot
Source ICAM Target CD200 CD200 Cell-Cell Contact 0.3959 0.00000000000000000003279234763405005 Scatter Plot
Source ICAM Target JAM JAM Cell-Cell Contact 0.3967 0.00000000000000000002720562121230053 Scatter Plot
Target ICAM Target CLEC CLEC Cell-Cell Contact 0.4008 0.000000000000000000010091139385877599 Scatter Plot
Source ICAM Target TENASCIN TENASCIN ECM-Receptor 0.4052 0.00000000000000000000352247197847298 Scatter Plot
Source ICAM Target APP APP Cell-Cell Contact 0.4053 0.00000000000000000000344839862231649 Scatter Plot
Source ICAM Target FGF FGF Secreted Signaling 0.4058 0.0000000000000000000029802117347605958 Scatter Plot
Source ICAM Target BAFF BAFF Secreted Signaling 0.4093 0.000000000000000000001269191768284157 Scatter Plot
Source ICAM Target ESAM ESAM Cell-Cell Contact 0.4123 0.0000000000000000000006057846065630438 Scatter Plot
Source ICAM Source IL7 IL7 Secreted Signaling 0.4186 0.00000000000000000000012201700103817353 Scatter Plot
Source ICAM Target SLURP SLURP Secreted Signaling 0.4270 0.0000000000000000000000140452822048616 Scatter Plot
Source ICAM Target CD34 CD34 Cell-Cell Contact 0.4297 0.00000000000000000000000681949077191674 Scatter Plot
Source ICAM Target WNT WNT Secreted Signaling 0.4357 0.0000000000000000000000013795749620221643 Scatter Plot
Source ICAM Target ncWNT ncWNT Secreted Signaling 0.4376 0.0000000000000000000000008348332086129187 Scatter Plot
Source ICAM Target CD39 CD39 Cell-Cell Contact 0.4449 0.00000000000000000000000010936324060638086 Scatter Plot
Source ICAM Target SEMA4 SEMA4 Cell-Cell Contact 0.4588 0.0000000000000000000000000020999499511629304 Scatter Plot
Source ICAM Target MIF MIF Secreted Signaling 0.4665 0.00000000000000000000000000021578278416053757 Scatter Plot
Target ICAM Target CEACAM CEACAM Cell-Cell Contact 0.4766 0.000000000000000000000000000010183219028833417 Scatter Plot
Target ICAM Target CD52 CD52 Cell-Cell Contact 0.4818 0.0000000000000000000000000000019884953585527897 Scatter Plot
Target ICAM Target PTN PTN Secreted Signaling -0.4166 0.00000000000000000000020590767090750216 Scatter Plot
Target ICAM Target SEMA7 SEMA7 Cell-Cell Contact -0.3608 0.00000000000000008097658787563771 Scatter Plot
Target ICAM Target IGF IGF Secreted Signaling -0.3566 0.000000000000000194102188572135 Scatter Plot
Target ICAM Target NRG NRG Secreted Signaling -0.3257 0.00000000000008001963303638593 Scatter Plot
Target ICAM Target VISFATIN VISFATIN Secreted Signaling -0.3242 0.00000000000010509480248743897 Scatter Plot
Source ICAM Source COMPLEMENT COMPLEMENT Secreted Signaling -0.3017 0.000000000005569301454011587 Scatter Plot
Source ICAM Target VCAM VCAM Cell-Cell Contact -0.2898 0.00000000003923167174072317 Scatter Plot
Target ICAM Target AGT AGT Secreted Signaling -0.2807 0.00000000016571746043149495 Scatter Plot
Target ICAM Target EPHB EPHB Cell-Cell Contact -0.2798 0.00000000018964115013065595 Scatter Plot
Source ICAM Source CD52 CD52 Cell-Cell Contact -0.2774 0.00000000027760438775019107 Scatter Plot
Source ICAM Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.2735 0.000000000496452285841615 Scatter Plot
Target ICAM Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.2491 0.000000016568111234938424 Scatter Plot
Source ICAM Target CEACAM CEACAM Cell-Cell Contact -0.2311 0.00000017437288352298614 Scatter Plot
Target ICAM Target BAFF BAFF Secreted Signaling -0.1965 0.00000962733985216244 Scatter Plot
Source ICAM Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1958 0.000010300539113195476 Scatter Plot
Source ICAM Target ANNEXIN ANNEXIN Secreted Signaling -0.1945 0.000011877135481968052 Scatter Plot
Source ICAM Source ANNEXIN ANNEXIN Secreted Signaling -0.1822 0.00004169625620017424 Scatter Plot
Source ICAM Target CCL CCL Secreted Signaling -0.1815 0.00004452308699643512 Scatter Plot
Source ICAM Target IL1 IL1 Secreted Signaling -0.1784 0.00006017948600103616 Scatter Plot
Target ICAM Target ADIPONECTIN ADIPONECTIN Secreted Signaling -0.1744 0.00008851171861438828 Scatter Plot
Target ICAM Target OSM OSM Secreted Signaling -0.1641 0.0002279393043704 Scatter Plot
Source ICAM Target CXCL CXCL Secreted Signaling -0.1603 0.0003202095074514 Scatter Plot
Source ICAM Source CLEC CLEC Cell-Cell Contact -0.1573 0.0004138888046819 Scatter Plot
Source ICAM Target CD52 CD52 Cell-Cell Contact -0.1520 0.0006499569976069 Scatter Plot
Source ICAM Target GRN GRN Secreted Signaling -0.1494 0.0008020788264307 Scatter Plot
Source ICAM Target SELE SELE Cell-Cell Contact -0.1480 0.0009044111209284 Scatter Plot
Source ICAM Source MIF MIF Secreted Signaling -0.1424 0.0014063844730302 Scatter Plot
Target ICAM Target NOTCH NOTCH Cell-Cell Contact -0.1373 0.002094081921066 Scatter Plot
Source ICAM Source IL1 IL1 Secreted Signaling -0.1274 0.0043336799487627 Scatter Plot
Source ICAM Target IFN-II IFN-II Secreted Signaling -0.1261 0.0047310125850217 Scatter Plot
Source ICAM Target IL17 IL17 Secreted Signaling -0.1206 0.006925120472506 Scatter Plot
Source ICAM Target VEGF VEGF Secreted Signaling -0.1184 0.0080338044567411 Scatter Plot
Source ICAM Target ANGPTL ANGPTL Secreted Signaling -0.1174 0.0085956221815521 Scatter Plot
Target ICAM Target TWEAK TWEAK Secreted Signaling -0.1171 0.0087502667983411 Scatter Plot
Source ICAM Target THY1 THY1 Cell-Cell Contact -0.1152 0.009906188213287 Scatter Plot
Source ICAM Target COLLAGEN COLLAGEN ECM-Receptor -0.1139 0.010823508853077 Scatter Plot
Target ICAM Target PECAM1 PECAM1 Cell-Cell Contact -0.1137 0.010921657386826 Scatter Plot
Source ICAM Target CLEC CLEC Cell-Cell Contact -0.1130 0.0114193279809679 Scatter Plot
Source ICAM Target CD23 CD23 Cell-Cell Contact -0.1130 0.0114524469445447 Scatter Plot
Target ICAM Target CD22 CD22 Cell-Cell Contact -0.1126 0.0117698624413362 Scatter Plot
Target ICAM Target IL6 IL6 Secreted Signaling -0.1031 0.0211500459471174 Scatter Plot
Source ICAM Target CD45 CD45 Cell-Cell Contact -0.1017 0.0229685562127138 Scatter Plot
Source ICAM Source SPP1 SPP1 Secreted Signaling -0.0978 0.0287913599754078 Scatter Plot

Cells that are targets of ICAM from HSCs*

Cells that are source of ICAM to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.