Pathway: TENASCIN

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: ECM-Receptor

Details on the TENASCIN pathway:

Specificity Index HSPC as target: 0.122
HSPC as source: 0.301

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the TENASCIN pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target TENASCIN Source AGRN AGRN ECM-Receptor 0.1040 0.0199874999136262 Scatter Plot
Target TENASCIN Source SEMA6 SEMA6 Cell-Cell Contact 0.1142 0.0105901092882112 Scatter Plot
Target TENASCIN Source GALECTIN GALECTIN Secreted Signaling 0.1231 0.0058408832793018 Scatter Plot
Target TENASCIN Target SEMA3 SEMA3 Secreted Signaling 0.1354 0.0024141652467938 Scatter Plot
Target TENASCIN Target NOTCH NOTCH Cell-Cell Contact 0.1455 0.001107094071001 Scatter Plot
Target TENASCIN Source WNT WNT Secreted Signaling 0.1524 0.0006283516952099 Scatter Plot
Target TENASCIN Target NCAM NCAM Cell-Cell Contact 0.1770 0.00006887021841560838 Scatter Plot
Target TENASCIN Target VEGF VEGF Secreted Signaling 0.1837 0.00003601683663333914 Scatter Plot
Target TENASCIN Source CD1D2 CD1D2 Cell-Cell Contact 0.1894 0.0000200672055771358 Scatter Plot
Target TENASCIN Source APELIN APELIN Secreted Signaling 0.1934 0.000013326881404439183 Scatter Plot
Target TENASCIN Source THBS THBS ECM-Receptor 0.1958 0.00001037459676264806 Scatter Plot
Target TENASCIN Source ANGPTL ANGPTL Secreted Signaling 0.2017 0.000005484808141291095 Scatter Plot
Target TENASCIN Target GDF GDF Secreted Signaling 0.2054 0.000003659220533622128 Scatter Plot
Target TENASCIN Source IL1 IL1 Secreted Signaling 0.2111 0.000001912049118590158 Scatter Plot
Target TENASCIN Source IL16 IL16 Secreted Signaling 0.2129 0.0000015488059635597535 Scatter Plot
Target TENASCIN Source SEMA3 SEMA3 Secreted Signaling 0.2163 0.000001045055975200253 Scatter Plot
Target TENASCIN Source GDF GDF Secreted Signaling 0.2219 0.0000005366617346004012 Scatter Plot
Target TENASCIN Target RANKL RANKL Secreted Signaling 0.2291 0.00000022377492827640205 Scatter Plot
Target TENASCIN Source VEGF VEGF Secreted Signaling 0.2302 0.00000019380070820242846 Scatter Plot
Target TENASCIN Source ncWNT ncWNT Secreted Signaling 0.2330 0.00000013686367264034836 Scatter Plot
Target TENASCIN Source FGF FGF Secreted Signaling 0.2398 0.0000000569367430593154 Scatter Plot
Target TENASCIN Source CD39 CD39 Cell-Cell Contact 0.2537 0.000000008746000772239418 Scatter Plot
Target TENASCIN Source CADM CADM Cell-Cell Contact 0.2549 0.000000007452166053727397 Scatter Plot
Target TENASCIN Source GP1BA GP1BA Cell-Cell Contact 0.2577 0.0000000049949616792783965 Scatter Plot
Target TENASCIN Source CCL CCL Secreted Signaling 0.2624 0.000000002572673249004308 Scatter Plot
Target TENASCIN Source THY1 THY1 Cell-Cell Contact 0.2858 0.00000000007455085378016833 Scatter Plot
Target TENASCIN Source CD46 CD46 Cell-Cell Contact 0.2919 0.000000000028116894069069768 Scatter Plot
Target TENASCIN Source PTN PTN Secreted Signaling 0.2935 0.000000000021732511642387185 Scatter Plot
Target TENASCIN Source RANKL RANKL Secreted Signaling 0.2965 0.000000000013305882014459375 Scatter Plot
Target TENASCIN Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.3064 0.0000000000024821440114080817 Scatter Plot
Target TENASCIN Source NT NT Secreted Signaling 0.3137 0.0000000000007023445521485896 Scatter Plot
Target TENASCIN Source CSF CSF Secreted Signaling 0.3250 0.00000000000009198377065478044 Scatter Plot
Target TENASCIN Source IGF IGF Secreted Signaling 0.3346 0.000000000000015290726055805692 Scatter Plot
Target TENASCIN Source NOTCH NOTCH Cell-Cell Contact 0.3376 0.000000000000008511680012410848 Scatter Plot
Target TENASCIN Source CD86 CD86 Cell-Cell Contact 0.3407 0.000000000000004645809694798041 Scatter Plot
Target TENASCIN Target SEMA5 SEMA5 Cell-Cell Contact 0.3443 0.0000000000000022976077252363028 Scatter Plot
Target TENASCIN Source CD45 CD45 Cell-Cell Contact 0.3573 0.00000000000000016725728605280144 Scatter Plot
Target TENASCIN Source IL2 IL2 Secreted Signaling 0.3754 0.0000000000000000035189417019882296 Scatter Plot
Target TENASCIN Source LIGHT LIGHT Secreted Signaling 0.3763 0.000000000000000002890879207822919 Scatter Plot
Target TENASCIN Target KIT KIT Secreted Signaling 0.3952 0.0000000000000000000383671118105588 Scatter Plot
Target TENASCIN Target EPHB EPHB Cell-Cell Contact 0.3964 0.00000000000000000002904772090426115 Scatter Plot
Target TENASCIN Source PSAP PSAP Secreted Signaling 0.3998 0.000000000000000000012731986429758023 Scatter Plot
Target TENASCIN Target CD200 CD200 Cell-Cell Contact 0.4028 0.000000000000000000006272207400742113 Scatter Plot
Target TENASCIN Source LAMININ LAMININ ECM-Receptor 0.4046 0.000000000000000000004062677542200287 Scatter Plot
Target TENASCIN Target BMP BMP Secreted Signaling 0.4048 0.00000000000000000000382198742014363 Scatter Plot
Target TENASCIN Source ICAM ICAM Cell-Cell Contact 0.4052 0.00000000000000000000352247197847298 Scatter Plot
Target TENASCIN Target TGFb TGFb Secreted Signaling 0.4070 0.000000000000000000002253427299473028 Scatter Plot
Target TENASCIN Source LCK LCK Cell-Cell Contact 0.4094 0.000000000000000000001257909114450109 Scatter Plot
Target TENASCIN Source CXCL CXCL Secreted Signaling 0.4098 0.000000000000000000001125277464316123 Scatter Plot
Target TENASCIN Source CX3C CX3C Secreted Signaling 0.4253 0.00000000000000000000002177955875940353 Scatter Plot
Target TENASCIN Source MK MK Secreted Signaling 0.4315 0.00000000000000000000000422257090171105 Scatter Plot
Target TENASCIN Source EPHB EPHB Cell-Cell Contact 0.4504 0.000000000000000000000000023806274430604382 Scatter Plot
Target TENASCIN Source CDH CDH Cell-Cell Contact 0.4625 0.00000000000000000000000000071336877266998645 Scatter Plot
Target TENASCIN Source FLT3 FLT3 Secreted Signaling 0.5063 0.0000000000000000000000000000000006442504488808366 Scatter Plot
Target TENASCIN Source SEMA7 SEMA7 Cell-Cell Contact 0.5070 0.0000000000000000000000000000000005008929461563828 Scatter Plot
Target TENASCIN Source BST2 BST2 Cell-Cell Contact 0.5143 0.000000000000000000000000000000000039948455551957245 Scatter Plot
Target TENASCIN Source IL7 IL7 Secreted Signaling 0.5161 0.000000000000000000000000000000000021494624724820032 Scatter Plot
Target TENASCIN Target SLURP SLURP Secreted Signaling 0.5241 0.0000000000000000000000000000000000012564843047601111 Scatter Plot
Target TENASCIN Source PROS PROS Secreted Signaling 0.5299 0.00000000000000000000000000000000000014667592956345757 Scatter Plot
Target TENASCIN Target MIF MIF Secreted Signaling 0.5346 0.0000000000000000000000000000000000000263313590539678 Scatter Plot
Target TENASCIN Source COLLAGEN COLLAGEN ECM-Receptor 0.5445 0.00000000000000000000000000000000000000059177306717772906 Scatter Plot
Target TENASCIN Source GAS GAS Secreted Signaling 0.5448 0.00000000000000000000000000000000000000053444924101474815 Scatter Plot
Target TENASCIN Source PDGF PDGF Secreted Signaling 0.5537 0.000000000000000000000000000000000000000016207573710826774 Scatter Plot
Target TENASCIN Target WNT WNT Secreted Signaling 0.5588 0.0000000000000000000000000000000000000000020054096778652097 Scatter Plot
Target TENASCIN Target FGF FGF Secreted Signaling 0.5623 0.00000000000000000000000000000000000000000047963561817850936 Scatter Plot
Target TENASCIN Source TWEAK TWEAK Secreted Signaling 0.5718 0.000000000000000000000000000000000000000000009272416808318833 Scatter Plot
Target TENASCIN Source BMP BMP Secreted Signaling 0.5798 0.0000000000000000000000000000000000000000000002944048750332848 Scatter Plot
Target TENASCIN Source LIFR LIFR Secreted Signaling 0.5815 0.0000000000000000000000000000000000000000000001393340511225104 Scatter Plot
Target TENASCIN Target CD39 CD39 Cell-Cell Contact 0.6109 0.00000000000000000000000000000000000000000000000000017084048900191538 Scatter Plot
Target TENASCIN Source MHC-II MHC-II Cell-Cell Contact 0.6511 0.0000000000000000000000000000000000000000000000000000000000001167676603577108 Scatter Plot
Target TENASCIN Source ESAM ESAM Cell-Cell Contact 0.6566 0.000000000000000000000000000000000000000000000000000000000000005033093517422592 Scatter Plot
Target TENASCIN Source ANGPT ANGPT Secreted Signaling 0.6599 0.0000000000000000000000000000000000000000000000000000000000000007566182775638666 Scatter Plot
Target TENASCIN Source MHC-I MHC-I Cell-Cell Contact 0.6778 0.00000000000000000000000000000000000000000000000000000000000000000001506187487524203 Scatter Plot
Target TENASCIN Source JAM JAM Cell-Cell Contact 0.7123 0.0000000000000000000000000000000000000000000000000000000000000000000000000000012071294537528632 Scatter Plot
Target TENASCIN Source CD52 CD52 Cell-Cell Contact -0.5312 0.00000000000000000000000000000000000009310435485114442 Scatter Plot
Target TENASCIN Source SELL SELL Cell-Cell Contact -0.5211 0.0000000000000000000000000000000000036674340233469504 Scatter Plot
Target TENASCIN Source COMPLEMENT COMPLEMENT Secreted Signaling -0.4950 0.00000000000000000000000000000002827811298519365 Scatter Plot
Target TENASCIN Source PARs PARs Secreted Signaling -0.4438 0.00000000000000000000000014880154509283323 Scatter Plot
Target TENASCIN Source SEMA4 SEMA4 Cell-Cell Contact -0.4311 0.0000000000000000000000048054355609902815 Scatter Plot
Target TENASCIN Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.4285 0.000000000000000000000009552132997178857 Scatter Plot
Target TENASCIN Source ANNEXIN ANNEXIN Secreted Signaling -0.3564 0.000000000000000202238960544868 Scatter Plot
Target TENASCIN Source VISTA VISTA Cell-Cell Contact -0.3307 0.00000000000003191849753374103 Scatter Plot
Target TENASCIN Source CCL CCL Secreted Signaling -0.3295 0.000000000000039930572031376196 Scatter Plot
Target TENASCIN Target CSF CSF Secreted Signaling -0.2967 0.000000000012757065822529816 Scatter Plot
Target TENASCIN Source ANGPTL ANGPTL Secreted Signaling -0.2799 0.00000000018803359028386542 Scatter Plot
Target TENASCIN Source CLEC CLEC Cell-Cell Contact -0.2776 0.0000000002666614692534517 Scatter Plot
Target TENASCIN Source MIF MIF Secreted Signaling -0.2333 0.00000013063744237920108 Scatter Plot
Target TENASCIN Target IL17 IL17 Secreted Signaling -0.2308 0.00000018012083781859667 Scatter Plot
Target TENASCIN Source TNF TNF Secreted Signaling -0.2256 0.0000003452545066064258 Scatter Plot
Target TENASCIN Source SPP1 SPP1 Secreted Signaling -0.2141 0.0000013589030873526195 Scatter Plot
Target TENASCIN Source NCAM NCAM Cell-Cell Contact -0.2105 0.0000020396726373829854 Scatter Plot
Target TENASCIN Source APP APP Cell-Cell Contact -0.1995 0.00000695492559019836 Scatter Plot
Target TENASCIN Source TGFb TGFb Secreted Signaling -0.1797 0.00005315214821345827 Scatter Plot
Target TENASCIN Source VISFATIN VISFATIN Secreted Signaling -0.1711 0.000121173198306 Scatter Plot
Target TENASCIN Source SELPLG SELPLG Cell-Cell Contact -0.1703 0.0001305050272507 Scatter Plot
Target TENASCIN Source LAIR1 LAIR1 Cell-Cell Contact -0.1680 0.0001603579544346 Scatter Plot
Target TENASCIN Target SEMA3 SEMA3 Secreted Signaling -0.1669 0.0001774122343328 Scatter Plot
Target TENASCIN Source NKG2D NKG2D Cell-Cell Contact -0.1144 0.0104728409333154 Scatter Plot
Target TENASCIN Target SELE SELE Cell-Cell Contact -0.1060 0.0176954302268591 Scatter Plot
Target TENASCIN Target ANNEXIN ANNEXIN Secreted Signaling -0.1010 0.0239342222119582 Scatter Plot
Target TENASCIN Target CXCL CXCL Secreted Signaling 0.1230 0.0058781508155736 Scatter Plot
Target TENASCIN Target NODAL NODAL Secreted Signaling 0.1696 0.0001389503210569 Scatter Plot
Target TENASCIN Target GAS GAS Secreted Signaling 0.1706 0.000126574756196 Scatter Plot
Target TENASCIN Target EPHA EPHA Cell-Cell Contact 0.2026 0.00000493580312455516 Scatter Plot
Target TENASCIN Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2282 0.0000002477667174791555 Scatter Plot
Target TENASCIN Target AGT AGT Secreted Signaling 0.2370 0.0000000815884011703494 Scatter Plot
Target TENASCIN Target CADM CADM Cell-Cell Contact 0.2549 0.000000007452166053727397 Scatter Plot
Target TENASCIN Target IL6 IL6 Secreted Signaling 0.2644 0.000000001919690297088299 Scatter Plot
Target TENASCIN Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2694 0.0000000009161357633655479 Scatter Plot
Target TENASCIN Target OSM OSM Secreted Signaling 0.2911 0.00000000003190744981320133 Scatter Plot
Target TENASCIN Target SEMA6 SEMA6 Cell-Cell Contact 0.3105 0.0000000000012237222701340832 Scatter Plot
Target TENASCIN Target ACTIVIN ACTIVIN Secreted Signaling 0.3472 0.0000000000000012984424709249785 Scatter Plot
Target TENASCIN Target CD22 CD22 Cell-Cell Contact 0.3573 0.00000000000000016725728605279774 Scatter Plot
Target TENASCIN Target TGFb TGFb Secreted Signaling 0.4127 0.0000000000000000000005407465506925626 Scatter Plot
Target TENASCIN Target NPR2 NPR2 Secreted Signaling 0.4368 0.0000000000000000000000010126589117825726 Scatter Plot
Target TENASCIN Target BAFF BAFF Secreted Signaling 0.4534 0.000000000000000000000000010037019721132582 Scatter Plot
Target TENASCIN Target CDH CDH Cell-Cell Contact 0.4625 0.00000000000000000000000000071336877266998645 Scatter Plot
Target TENASCIN Target SEMA4 SEMA4 Cell-Cell Contact 0.4823 0.0000000000000000000000000000016910244173674762 Scatter Plot
Target TENASCIN Target APP APP Cell-Cell Contact 0.5028 0.0000000000000000000000000000000021458183403668565 Scatter Plot
Target TENASCIN Target ncWNT ncWNT Secreted Signaling 0.5432 0.0000000000000000000000000000000000000009721433231850118 Scatter Plot
Target TENASCIN Target PARs PARs Secreted Signaling 0.6411 0.00000000000000000000000000000000000000000000000000000000003001608460697362 Scatter Plot
Target TENASCIN Target ESAM ESAM Cell-Cell Contact 0.6566 0.000000000000000000000000000000000000000000000000000000000000005033093517422592 Scatter Plot
Target TENASCIN Target CD34 CD34 Cell-Cell Contact 0.6951 0.00000000000000000000000000000000000000000000000000000000000000000000000019802241566960863 Scatter Plot
Target TENASCIN Target IFN-II IFN-II Secreted Signaling -0.4900 0.00000000000000000000000000000014484569144851536 Scatter Plot
Target TENASCIN Target CD52 CD52 Cell-Cell Contact -0.4492 0.00000000000000000000000003271106379939321 Scatter Plot
Target TENASCIN Target ICAM ICAM Cell-Cell Contact -0.4045 0.0000000000000000000041241408612377024 Scatter Plot
Target TENASCIN Target VCAM VCAM Cell-Cell Contact -0.3689 0.000000000000000014479309825149705 Scatter Plot
Target TENASCIN Target CCL CCL Secreted Signaling -0.3236 0.00000000000011915689570422436 Scatter Plot
Target TENASCIN Target CXCL CXCL Secreted Signaling -0.2943 0.000000000018949344883278217 Scatter Plot
Target TENASCIN Target CLEC CLEC Cell-Cell Contact -0.2936 0.00000000002119713798927585 Scatter Plot
Target TENASCIN Target CEACAM CEACAM Cell-Cell Contact -0.2758 0.00000000035377848966159926 Scatter Plot
Target TENASCIN Target VEGF VEGF Secreted Signaling -0.2361 0.0000000921236049228846 Scatter Plot
Target TENASCIN Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1557 0.0004767549453405 Scatter Plot
Target TENASCIN Target GRN GRN Secreted Signaling -0.1258 0.0048514849737049 Scatter Plot
Target TENASCIN Target PDGF PDGF Secreted Signaling -0.0989 0.0269625785463383 Scatter Plot

Cells that are targets of TENASCIN from HSCs*

    No cell populations

Cells that are source of TENASCIN to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.