Pathway: MIF

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Secreted Signaling

Details on the MIF pathway:

Specificity Index HSPC as target: 0.710
HSPC as source: 0.979

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the MIF pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target MIF Target LAIR1 LAIR1 Cell-Cell Contact 0.1009 0.0240289461743321 Scatter Plot
Target MIF Source PECAM1 PECAM1 Cell-Cell Contact 0.1060 0.0177084939526505 Scatter Plot
Target MIF Target PECAM1 PECAM1 Cell-Cell Contact 0.1060 0.0177084939526505 Scatter Plot
Target MIF Source OSM OSM Secreted Signaling 0.1075 0.0162090917623715 Scatter Plot
Target MIF Target IL1 IL1 Secreted Signaling 0.1159 0.0094657072672126 Scatter Plot
Target MIF Target GAS GAS Secreted Signaling 0.1182 0.0081604298834713 Scatter Plot
Target MIF Source THBS THBS ECM-Receptor 0.1189 0.0077609110640491 Scatter Plot
Source MIF Source VEGF VEGF Secreted Signaling 0.1376 0.0020460153177824 Scatter Plot
Source MIF Source GALECTIN GALECTIN Secreted Signaling 0.1409 0.0015823680746773 Scatter Plot
Target MIF Source SEMA6 SEMA6 Cell-Cell Contact 0.1421 0.0014389710634579 Scatter Plot
Target MIF Source APELIN APELIN Secreted Signaling 0.1599 0.0003301885582434 Scatter Plot
Target MIF Source CD34 CD34 Cell-Cell Contact 0.1757 0.00007799746467466733 Scatter Plot
Target MIF Source IL6 IL6 Secreted Signaling 0.1829 0.00003892181173000883 Scatter Plot
Target MIF Source PTN PTN Secreted Signaling 0.1853 0.00003070371601824367 Scatter Plot
Target MIF Target MK MK Secreted Signaling 0.1869 0.000026032171984770623 Scatter Plot
Target MIF Source ICOS ICOS Cell-Cell Contact 0.1949 0.00001139876933200328 Scatter Plot
Target MIF Source ncWNT ncWNT Secreted Signaling 0.1980 0.000008151917244032795 Scatter Plot
Target MIF Target NOTCH NOTCH Cell-Cell Contact 0.2042 0.000004176044057208868 Scatter Plot
Source MIF Source SEMA4 SEMA4 Cell-Cell Contact 0.2128 0.0000015658849281540023 Scatter Plot
Target MIF Target SEMA3 SEMA3 Secreted Signaling 0.2218 0.0000005417942502889426 Scatter Plot
Target MIF Target RANKL RANKL Secreted Signaling 0.2402 0.00000005418141862194979 Scatter Plot
Target MIF Target NCAM NCAM Cell-Cell Contact 0.2415 0.0000000455595143867969 Scatter Plot
Target MIF Source CD1D2 CD1D2 Cell-Cell Contact 0.2445 0.000000030410271882105434 Scatter Plot
Target MIF Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2505 0.00000001364922760350233 Scatter Plot
Target MIF Target VEGF VEGF Secreted Signaling 0.2542 0.000000008121906240499057 Scatter Plot
Target MIF Source NT NT Secreted Signaling 0.2560 0.0000000063813203275358605 Scatter Plot
Source MIF Source VISFATIN VISFATIN Secreted Signaling 0.2560 0.000000006310154486678463 Scatter Plot
Target MIF Source SEMA3 SEMA3 Secreted Signaling 0.2591 0.000000004096140373037622 Scatter Plot
Source MIF Source SELPLG SELPLG Cell-Cell Contact 0.2624 0.000000002541470664308173 Scatter Plot
Target MIF Target CADM CADM Cell-Cell Contact 0.2675 0.0000000012181839803755547 Scatter Plot
Target MIF Source CADM CADM Cell-Cell Contact 0.2675 0.0000000012181839803755547 Scatter Plot
Target MIF Source GDF GDF Secreted Signaling 0.2742 0.000000000450100337863014 Scatter Plot
Target MIF Target EPHA EPHA Cell-Cell Contact 0.2762 0.00000000033361889001628315 Scatter Plot
Target MIF Source ANGPTL ANGPTL Secreted Signaling 0.2843 0.00000000009427349241230139 Scatter Plot
Source MIF Source SELL SELL Cell-Cell Contact 0.2987 0.0000000000091644813985016 Scatter Plot
Target MIF Target GDF GDF Secreted Signaling 0.3009 0.000000000006310324549933689 Scatter Plot
Target MIF Source WNT WNT Secreted Signaling 0.3030 0.0000000000044576771619649826 Scatter Plot
Target MIF Target SEMA7 SEMA7 Cell-Cell Contact 0.3131 0.0000000000007756079135033441 Scatter Plot
Target MIF Source THY1 THY1 Cell-Cell Contact 0.3147 0.00000000000058587696279775 Scatter Plot
Target MIF Source VEGF VEGF Secreted Signaling 0.3169 0.00000000000039749645397288804 Scatter Plot
Target MIF Source CD46 CD46 Cell-Cell Contact 0.3181 0.00000000000031970538608556853 Scatter Plot
Target MIF Source VCAM VCAM Cell-Cell Contact 0.3303 0.000000000000034459057177793924 Scatter Plot
Target MIF Target NODAL NODAL Secreted Signaling 0.3303 0.000000000000034426321810906315 Scatter Plot
Target MIF Target SEMA5 SEMA5 Cell-Cell Contact 0.3472 0.0000000000000012989342491344985 Scatter Plot
Target MIF Source EPHB EPHB Cell-Cell Contact 0.3541 0.00000000000000032412407042053473 Scatter Plot
Target MIF Target ANGPTL ANGPTL Secreted Signaling 0.3601 0.00000000000000009256448264894981 Scatter Plot
Target MIF Source LIGHT LIGHT Secreted Signaling 0.3643 0.00000000000000003857451959335121 Scatter Plot
Target MIF Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.3753 0.000000000000000003608121577879082 Scatter Plot
Target MIF Target THBS THBS ECM-Receptor 0.3771 0.000000000000000002425167377480487 Scatter Plot
Target MIF Source CCL CCL Secreted Signaling 0.3782 0.0000000000000000019064301101503816 Scatter Plot
Target MIF Source CD39 CD39 Cell-Cell Contact 0.3804 0.0000000000000000011543150081703165 Scatter Plot
Target MIF Source RANKL RANKL Secreted Signaling 0.3875 0.00000000000000000023168194782000605 Scatter Plot
Target MIF Source CXCL CXCL Secreted Signaling 0.3887 0.00000000000000000017438416678507262 Scatter Plot
Source MIF Source CD34 CD34 Cell-Cell Contact 0.3894 0.00000000000000000014815904791083342 Scatter Plot
Target MIF Source NOTCH NOTCH Cell-Cell Contact 0.3903 0.00000000000000000012073257258578023 Scatter Plot
Target MIF Source LIFR LIFR Secreted Signaling 0.3904 0.00000000000000000011723915077766344 Scatter Plot
Target MIF Target VWF VWF ECM-Receptor 0.3974 0.00000000000000000002275003651334327 Scatter Plot
Target MIF Source PROS PROS Secreted Signaling 0.4279 0.000000000000000000000010940871774741944 Scatter Plot
Target MIF Source FLT3 FLT3 Secreted Signaling 0.4288 0.000000000000000000000008732472397838665 Scatter Plot
Target MIF Target ACTIVIN ACTIVIN Secreted Signaling 0.4368 0.000000000000000000000001012786586391772 Scatter Plot
Target MIF Target BMP BMP Secreted Signaling 0.4452 0.00000000000000000000000010069474762318543 Scatter Plot
Target MIF Target KIT KIT Secreted Signaling 0.4506 0.00000000000000000000000002240516451771045 Scatter Plot
Target MIF Source CX3C CX3C Secreted Signaling 0.4512 0.00000000000000000000000001898829802697728 Scatter Plot
Target MIF Source CSF CSF Secreted Signaling 0.4532 0.000000000000000000000000010640237775419768 Scatter Plot
Target MIF Source IGF IGF Secreted Signaling 0.4559 0.000000000000000000000000004907666003953089 Scatter Plot
Target MIF Target EPHB EPHB Cell-Cell Contact 0.4659 0.00000000000000000000000000026171675532707927 Scatter Plot
Target MIF Source ICAM ICAM Cell-Cell Contact 0.4665 0.00000000000000000000000000021578278416053757 Scatter Plot
Target MIF Source LAMININ LAMININ ECM-Receptor 0.4717 0.00000000000000000000000000004519632278693818 Scatter Plot
Target MIF Source LCK LCK Cell-Cell Contact 0.4774 0.00000000000000000000000000000779900761331727 Scatter Plot
Target MIF Target IGF IGF Secreted Signaling 0.4833 0.0000000000000000000000000000012374987621448315 Scatter Plot
Target MIF Source PDGF PDGF Secreted Signaling 0.5020 0.0000000000000000000000000000000028117566373734948 Scatter Plot
Target MIF Source CDH CDH Cell-Cell Contact 0.5024 0.0000000000000000000000000000000024066564391563725 Scatter Plot
Target MIF Target BSP BSP ECM-Receptor 0.5066 0.0000000000000000000000000000000005780197392055252 Scatter Plot
Target MIF Source IL16 IL16 Secreted Signaling 0.5108 0.00000000000000000000000000000000013917495068997758 Scatter Plot
Target MIF Source IL2 IL2 Secreted Signaling 0.5155 0.000000000000000000000000000000000027015395682099094 Scatter Plot
Target MIF Source MK MK Secreted Signaling 0.5272 0.000000000000000000000000000000000000395828573503582 Scatter Plot
Source MIF Source TGFb TGFb Secreted Signaling 0.5549 0.000000000000000000000000000000000000000009737960446052358 Scatter Plot
Target MIF Source CD45 CD45 Cell-Cell Contact 0.5555 0.000000000000000000000000000000000000000007852201673253741 Scatter Plot
Target MIF Source CD86 CD86 Cell-Cell Contact 0.5597 0.0000000000000000000000000000000000000000014178064909519255 Scatter Plot
Target MIF Target TGFb TGFb Secreted Signaling 0.5597 0.0000000000000000000000000000000000000000014027125287291749 Scatter Plot
Target MIF Source TWEAK TWEAK Secreted Signaling 0.5789 0.00000000000000000000000000000000000000000000043972664801963085 Scatter Plot
Target MIF Target FGF FGF Secreted Signaling 0.5811 0.00000000000000000000000000000000000000000000016846227305209021 Scatter Plot
Target MIF Source BST2 BST2 Cell-Cell Contact 0.5827 0.00000000000000000000000000000000000000000000008069232348918145 Scatter Plot
Source MIF Source ANGPTL ANGPTL Secreted Signaling 0.5849 0.00000000000000000000000000000000000000000000003054560531702121 Scatter Plot
Target MIF Source SEMA7 SEMA7 Cell-Cell Contact 0.5928 0.0000000000000000000000000000000000000000000000008610658127024044 Scatter Plot
Target MIF Source BMP BMP Secreted Signaling 0.6041 0.000000000000000000000000000000000000000000000000004549080259462026 Scatter Plot
Target MIF Target ESAM ESAM Cell-Cell Contact 0.6061 0.000000000000000000000000000000000000000000000000001752248244022726 Scatter Plot
Target MIF Source ESAM ESAM Cell-Cell Contact 0.6061 0.000000000000000000000000000000000000000000000000001752248244022726 Scatter Plot
Target MIF Target CD39 CD39 Cell-Cell Contact 0.6167 0.00000000000000000000000000000000000000000000000000000985860120505209 Scatter Plot
Target MIF Source IL7 IL7 Secreted Signaling 0.6233 0.0000000000000000000000000000000000000000000000000000003611148679367901 Scatter Plot
Target MIF Source PSAP PSAP Secreted Signaling 0.6365 0.00000000000000000000000000000000000000000000000000000000034946423254178815 Scatter Plot
Target MIF Target WNT WNT Secreted Signaling 0.6404 0.00000000000000000000000000000000000000000000000000000000004312687188322143 Scatter Plot
Target MIF Target SLURP SLURP Secreted Signaling 0.6419 0.000000000000000000000000000000000000000000000000000000000019084595143431716 Scatter Plot
Target MIF Target CD200 CD200 Cell-Cell Contact 0.6443 0.000000000000000000000000000000000000000000000000000000000005143776727539931 Scatter Plot
Target MIF Source ANGPT ANGPT Secreted Signaling 0.6616 0.0000000000000000000000000000000000000000000000000000000000000002799875553861911 Scatter Plot
Target MIF Source JAM JAM Cell-Cell Contact 0.6654 0.000000000000000000000000000000000000000000000000000000000000000028378908175212164 Scatter Plot
Target MIF Source GAS GAS Secreted Signaling 0.6667 0.000000000000000000000000000000000000000000000000000000000000000013640670686939625 Scatter Plot
Target MIF Source COLLAGEN COLLAGEN ECM-Receptor 0.6837 0.0000000000000000000000000000000000000000000000000000000000000000000003505834937937833 Scatter Plot
Target MIF Source MHC-I MHC-I Cell-Cell Contact 0.7413 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002390733784813692 Scatter Plot
Target MIF Source MHC-II MHC-II Cell-Cell Contact 0.8307 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546532095500627 Scatter Plot
Target MIF Source TGFb TGFb Secreted Signaling -0.4233 0.00000000000000000000003640811729035693 Scatter Plot
Source MIF Source GAS GAS Secreted Signaling -0.3841 0.0000000000000000005013510276603294 Scatter Plot
Source MIF Source TWEAK TWEAK Secreted Signaling -0.3518 0.0000000000000005151272841299928 Scatter Plot
Source MIF Source ESAM ESAM Cell-Cell Contact -0.3312 0.00000000000002872438277340215 Scatter Plot
Target MIF Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.3309 0.000000000000030594864772732026 Scatter Plot
Source MIF Source PSAP PSAP Secreted Signaling -0.3230 0.00000000000013142054514216062 Scatter Plot
Target MIF Source CD52 CD52 Cell-Cell Contact -0.3209 0.00000000000019352134741688912 Scatter Plot
Source MIF Source BMP BMP Secreted Signaling -0.3182 0.0000000000003144981296971746 Scatter Plot
Target MIF Source COMPLEMENT COMPLEMENT Secreted Signaling -0.3164 0.0000000000004307893447482075 Scatter Plot
Source MIF Source ANGPT ANGPT Secreted Signaling -0.3005 0.000000000006818076369017728 Scatter Plot
Source MIF Source FLT3 FLT3 Secreted Signaling -0.2912 0.000000000031565603417698714 Scatter Plot
Source MIF Source EPHB EPHB Cell-Cell Contact -0.2722 0.0000000006076888978030922 Scatter Plot
Source MIF Source CD39 CD39 Cell-Cell Contact -0.2670 0.000000001315230688964361 Scatter Plot
Target MIF Source PARs PARs Secreted Signaling -0.2599 0.000000003669960103303659 Scatter Plot
Source MIF Source VEGF VEGF Secreted Signaling -0.2467 0.000000022717709432637237 Scatter Plot
Target MIF Source ANGPTL ANGPTL Secreted Signaling -0.2445 0.000000030698859290837736 Scatter Plot
Target MIF Source SELL SELL Cell-Cell Contact -0.2428 0.00000003848600640573173 Scatter Plot
Source MIF Source LIGHT LIGHT Secreted Signaling -0.2419 0.00000004301382081593364 Scatter Plot
Source MIF Source MK MK Secreted Signaling -0.2402 0.000000054139133834785564 Scatter Plot
Source MIF Source GRN GRN Secreted Signaling -0.2347 0.00000010939284142952626 Scatter Plot
Source MIF Source CDH CDH Cell-Cell Contact -0.2294 0.00000021408056837728133 Scatter Plot
Source MIF Source LIFR LIFR Secreted Signaling -0.2288 0.0000002325497690160072 Scatter Plot
Source MIF Source PDGF PDGF Secreted Signaling -0.2275 0.000000270114705269044 Scatter Plot
Source MIF Source CADM CADM Cell-Cell Contact -0.2223 0.000000509960752546844 Scatter Plot
Target MIF Target CSF CSF Secreted Signaling -0.2177 0.0000008863940744565395 Scatter Plot
Source MIF Source NOTCH NOTCH Cell-Cell Contact -0.2142 0.0000013376911044439135 Scatter Plot
Target MIF Source SEMA4 SEMA4 Cell-Cell Contact -0.2008 0.000006063733276121013 Scatter Plot
Target MIF Source CLEC CLEC Cell-Cell Contact -0.1917 0.000015945583167959785 Scatter Plot
Source MIF Source CD46 CD46 Cell-Cell Contact -0.1915 0.000016297614847089468 Scatter Plot
Target MIF Target IL17 IL17 Secreted Signaling -0.1864 0.00002742166051338238 Scatter Plot
Target MIF Source NCAM NCAM Cell-Cell Contact -0.1807 0.00004812639247296599 Scatter Plot
Source MIF Source PROS PROS Secreted Signaling -0.1805 0.00004908076673144822 Scatter Plot
Source MIF Source RANKL RANKL Secreted Signaling -0.1628 0.0002568172303765 Scatter Plot
Target MIF Source VISTA VISTA Cell-Cell Contact -0.1624 0.0002646442102649 Scatter Plot
Source MIF Source ncWNT ncWNT Secreted Signaling -0.1439 0.001253606567223 Scatter Plot
Source MIF Source ICAM ICAM Cell-Cell Contact -0.1424 0.0014063844730302 Scatter Plot
Target MIF Source NKG2D NKG2D Cell-Cell Contact -0.1350 0.0024796782744004 Scatter Plot
Target MIF Target VEGF VEGF Secreted Signaling -0.1312 0.0032830920184641 Scatter Plot
Target MIF Source SPP1 SPP1 Secreted Signaling -0.1284 0.0040327535134866 Scatter Plot
Target MIF Source VISFATIN VISFATIN Secreted Signaling -0.1217 0.0064152236657173 Scatter Plot
Source MIF Source SEMA3 SEMA3 Secreted Signaling -0.1215 0.0065342103396447 Scatter Plot
Source MIF Source NCAM NCAM Cell-Cell Contact -0.1174 0.0085814510079552 Scatter Plot
Target MIF Target GRN GRN Secreted Signaling -0.1098 0.014013110522277 Scatter Plot
Target MIF Source GALECTIN GALECTIN Secreted Signaling -0.1097 0.0141295717911468 Scatter Plot
Source MIF Source THBS THBS ECM-Receptor -0.1065 0.0172272105314575 Scatter Plot
Source MIF Source PECAM1 PECAM1 Cell-Cell Contact -0.0965 0.031040630428615 Scatter Plot
Source MIF Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.0966 0.0308415575764119 Scatter Plot
Target MIF Target BST2 BST2 Cell-Cell Contact 0.1009 0.0240289461743322 Scatter Plot
Source MIF Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1040 0.0199794837044466 Scatter Plot
Source MIF Source CLEC CLEC Cell-Cell Contact 0.1120 0.0122143436047227 Scatter Plot
Target MIF Target TWEAK TWEAK Secreted Signaling 0.1147 0.0102488485541512 Scatter Plot
Source MIF Target IFN-II IFN-II Secreted Signaling 0.1172 0.0086832579852583 Scatter Plot
Source MIF Target SEMA3 SEMA3 Secreted Signaling 0.1192 0.0076364306460625 Scatter Plot
Source MIF Target CXCL CXCL Secreted Signaling 0.1376 0.0020445982967245 Scatter Plot
Target MIF Target AGT AGT Secreted Signaling 0.1486 0.0008621451354839 Scatter Plot
Source MIF Target MK MK Secreted Signaling 0.1604 0.000317623097432 Scatter Plot
Target MIF Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1612 0.0002943854668951 Scatter Plot
Source MIF Target CLEC CLEC Cell-Cell Contact 0.1692 0.0001439902489726 Scatter Plot
Target MIF Target SELL SELL Cell-Cell Contact 0.1765 0.0000726931948606773 Scatter Plot
Target MIF Target MK MK Secreted Signaling 0.1794 0.00005475325711433871 Scatter Plot
Source MIF Target CD52 CD52 Cell-Cell Contact 0.1956 0.000010542565372108605 Scatter Plot
Source MIF Source CD52 CD52 Cell-Cell Contact 0.1990 0.000007328082472107552 Scatter Plot
Source MIF Target SELPLG SELPLG Cell-Cell Contact 0.2044 0.000004065030289066744 Scatter Plot
Source MIF Target VEGF VEGF Secreted Signaling 0.2049 0.000003839169791116582 Scatter Plot
Target MIF Target PTN PTN Secreted Signaling 0.2130 0.0000015411710806347469 Scatter Plot
Source MIF Target TWEAK TWEAK Secreted Signaling 0.2139 0.0000013814172199591904 Scatter Plot
Target MIF Target OSM OSM Secreted Signaling 0.2151 0.000001209256371824797 Scatter Plot
Target MIF Target THY1 THY1 Cell-Cell Contact 0.2598 0.000000003734581785425479 Scatter Plot
Source MIF Target CCL CCL Secreted Signaling 0.2737 0.0000000004813399661941751 Scatter Plot
Source MIF Target PTN PTN Secreted Signaling 0.2870 0.00000000006130481781773905 Scatter Plot
Target MIF Target CD23 CD23 Cell-Cell Contact 0.2917 0.0000000000287688068210878 Scatter Plot
Target MIF Target CSPG4 CSPG4 Cell-Cell Contact 0.3009 0.000000000006306397321670426 Scatter Plot
Target MIF Target IL6 IL6 Secreted Signaling 0.3325 0.00000000000002278263607264129 Scatter Plot
Source MIF Source PARs PARs Secreted Signaling 0.3483 0.0000000000000010468941275278416 Scatter Plot
Target MIF Target SEMA6 SEMA6 Cell-Cell Contact 0.3515 0.0000000000000005426266409916696 Scatter Plot
Target MIF Target PARs PARs Secreted Signaling 0.3566 0.00000000000000019246115430154503 Scatter Plot
Target MIF Target VISFATIN VISFATIN Secreted Signaling 0.3583 0.00000000000000013533191185587426 Scatter Plot
Source MIF Source CCL CCL Secreted Signaling 0.3636 0.000000000000000044642441105698513 Scatter Plot
Source MIF Target IL17 IL17 Secreted Signaling 0.3651 0.000000000000000032379676547528337 Scatter Plot
Source MIF Target SELL SELL Cell-Cell Contact 0.3898 0.00000000000000000013664489170994192 Scatter Plot
Target MIF Target VTN VTN ECM-Receptor 0.4265 0.00000000000000000000001605449756348045 Scatter Plot
Target MIF Target ANGPT ANGPT Secreted Signaling 0.4333 0.000000000000000000000002612771194596416 Scatter Plot
Source MIF Target CSF CSF Secreted Signaling 0.4405 0.0000000000000000000000003770442942029993 Scatter Plot
Target MIF Target NPR2 NPR2 Secreted Signaling 0.4717 0.000000000000000000000000000044648799466788913 Scatter Plot
Target MIF Target CDH CDH Cell-Cell Contact 0.5024 0.0000000000000000000000000000000024066564391563725 Scatter Plot
Target MIF Target DMP1 DMP1 ECM-Receptor 0.5041 0.0000000000000000000000000000000013607583468960268 Scatter Plot
Target MIF Target PERIOSTIN PERIOSTIN Secreted Signaling 0.5050 0.0000000000000000000000000000000010203730897943163 Scatter Plot
Target MIF Target NRG NRG Secreted Signaling 0.5135 0.00000000000000000000000000000000005390374750354387 Scatter Plot
Target MIF Target TENASCIN TENASCIN ECM-Receptor 0.5346 0.0000000000000000000000000000000000000263313590539678 Scatter Plot
Target MIF Target SEMA4 SEMA4 Cell-Cell Contact 0.5391 0.000000000000000000000000000000000000004785330017575684 Scatter Plot
Target MIF Target CD34 CD34 Cell-Cell Contact 0.5546 0.000000000000000000000000000000000000000011107571745896104 Scatter Plot
Target MIF Target CD22 CD22 Cell-Cell Contact 0.5555 0.000000000000000000000000000000000000000007852201673253179 Scatter Plot
Target MIF Target BAFF BAFF Secreted Signaling 0.5605 0.0000000000000000000000000000000000000000010305178729533378 Scatter Plot
Target MIF Target JAM JAM Cell-Cell Contact 0.6093 0.0000000000000000000000000000000000000000000000000003641011508573958 Scatter Plot
Target MIF Target ncWNT ncWNT Secreted Signaling 0.6367 0.0000000000000000000000000000000000000000000000000000000003188162330795047 Scatter Plot
Source MIF Target ADIPONECTIN ADIPONECTIN Secreted Signaling -0.5618 0.0000000000000000000000000000000000000000005946051910652529 Scatter Plot
Source MIF Target JAM JAM Cell-Cell Contact -0.5101 0.0000000000000000000000000000000001733618405159629 Scatter Plot
Source MIF Target CD22 CD22 Cell-Cell Contact -0.5084 0.0000000000000000000000000000000003103206189656676 Scatter Plot
Source MIF Source CD45 CD45 Cell-Cell Contact -0.5084 0.0000000000000000000000000000000003103206189656986 Scatter Plot
Source MIF Target NCAM NCAM Cell-Cell Contact -0.4829 0.0000000000000000000000000000014048250557857673 Scatter Plot
Source MIF Source IL16 IL16 Secreted Signaling -0.4783 0.000000000000000000000000000006005909368603294 Scatter Plot
Source MIF Target CD23 CD23 Cell-Cell Contact -0.4753 0.000000000000000000000000000015043105503647244 Scatter Plot
Source MIF Target IGF IGF Secreted Signaling -0.4524 0.000000000000000000000000013545780318268788 Scatter Plot
Source MIF Source MHC-I MHC-I Cell-Cell Contact -0.4356 0.0000000000000000000000014315648470441796 Scatter Plot
Source MIF Target THY1 THY1 Cell-Cell Contact -0.4349 0.000000000000000000000001733761162911052 Scatter Plot
Source MIF Target GALECTIN GALECTIN Secreted Signaling -0.4198 0.00000000000000000000008993022427551731 Scatter Plot
Source MIF Source JAM JAM Cell-Cell Contact -0.3563 0.00000000000000020422935632438634 Scatter Plot
Source MIF Target FGF FGF Secreted Signaling -0.3404 0.000000000000004911627600220667 Scatter Plot
Source MIF Target CD200 CD200 Cell-Cell Contact -0.3380 0.000000000000007851744744091139 Scatter Plot
Source MIF Source BAFF BAFF Secreted Signaling -0.3376 0.000000000000008606751327851544 Scatter Plot
Source MIF Target ESAM ESAM Cell-Cell Contact -0.3312 0.00000000000002872438277340268 Scatter Plot
Source MIF Target SEMA7 SEMA7 Cell-Cell Contact -0.3165 0.00000000000042361536145957543 Scatter Plot
Source MIF Source SEMA7 SEMA7 Cell-Cell Contact -0.3136 0.0000000000007175101131289057 Scatter Plot
Source MIF Target APP APP Cell-Cell Contact -0.3127 0.0000000000008296605511492165 Scatter Plot
Source MIF Source MHC-II MHC-II Cell-Cell Contact -0.3079 0.000000000001917852331152013 Scatter Plot
Source MIF Target CD39 CD39 Cell-Cell Contact -0.3053 0.0000000000030311673424816976 Scatter Plot
Source MIF Target THBS THBS ECM-Receptor -0.2946 0.000000000017955755357916143 Scatter Plot
Source MIF Source CX3C CX3C Secreted Signaling -0.2946 0.00000000001816358015929887 Scatter Plot
Source MIF Target SLURP SLURP Secreted Signaling -0.2900 0.000000000038258358923991454 Scatter Plot
Source MIF Source COLLAGEN COLLAGEN ECM-Receptor -0.2863 0.00000000006923349999873297 Scatter Plot
Target MIF Target ICAM ICAM Cell-Cell Contact -0.2790 0.00000000021574888408846276 Scatter Plot
Source MIF Target COMPLEMENT COMPLEMENT Secreted Signaling -0.2780 0.00000000025249770648575216 Scatter Plot
Source MIF Target ncWNT ncWNT Secreted Signaling -0.2763 0.00000000032459580980214837 Scatter Plot
Source MIF Target ANGPT ANGPT Secreted Signaling -0.2656 0.0000000016115989157895351 Scatter Plot
Source MIF Source CD86 CD86 Cell-Cell Contact -0.2631 0.000000002329131482891329 Scatter Plot
Source MIF Target ANGPTL ANGPTL Secreted Signaling -0.2592 0.0000000040150616249680726 Scatter Plot
Source MIF Target KIT KIT Secreted Signaling -0.2577 0.000000005007453275024128 Scatter Plot
Source MIF Target ANNEXIN ANNEXIN Secreted Signaling -0.2570 0.000000005538095044606581 Scatter Plot
Source MIF Target DMP1 DMP1 ECM-Receptor -0.2506 0.000000013462592405516412 Scatter Plot
Source MIF Target PARs PARs Secreted Signaling -0.2470 0.000000021798239219707 Scatter Plot
Source MIF Target BSP BSP ECM-Receptor -0.2445 0.000000030791610674834514 Scatter Plot
Target MIF Target CD52 CD52 Cell-Cell Contact -0.2443 0.000000031610291174366616 Scatter Plot
Source MIF Source MK MK Secreted Signaling -0.2402 0.000000054139133834783956 Scatter Plot
Target MIF Target VCAM VCAM Cell-Cell Contact -0.2370 0.00000008161597395718826 Scatter Plot
Source MIF Source IGF IGF Secreted Signaling -0.2362 0.00000009086681550619265 Scatter Plot
Source MIF Target TENASCIN TENASCIN ECM-Receptor -0.2333 0.00000013063744237920108 Scatter Plot
Source MIF Target CDH CDH Cell-Cell Contact -0.2294 0.00000021408056837728133 Scatter Plot
Source MIF Source IL7 IL7 Secreted Signaling -0.2273 0.0000002786309095601232 Scatter Plot
Source MIF Target NPR2 NPR2 Secreted Signaling -0.2267 0.0000003008254686238672 Scatter Plot
Source MIF Target PERIOSTIN PERIOSTIN Secreted Signaling -0.2254 0.0000003506986243652237 Scatter Plot
Source MIF Target TGFb TGFb Secreted Signaling -0.2251 0.0000003668000852599392 Scatter Plot
Source MIF Target BAFF BAFF Secreted Signaling -0.2232 0.00000046232125200014454 Scatter Plot
Source MIF Target IL1 IL1 Secreted Signaling -0.2231 0.0000004675994655694678 Scatter Plot
Source MIF Target CADM CADM Cell-Cell Contact -0.2223 0.0000005099607525468458 Scatter Plot
Source MIF Target NRG NRG Secreted Signaling -0.2200 0.0000006754534016238536 Scatter Plot
Source MIF Target WNT WNT Secreted Signaling -0.2190 0.0000007597209464379605 Scatter Plot
Source MIF Target LAMININ LAMININ ECM-Receptor -0.2160 0.0000010823973118103815 Scatter Plot
Source MIF Target BMP BMP Secreted Signaling -0.2115 0.0000018204578445546816 Scatter Plot
Source MIF Source ANNEXIN ANNEXIN Secreted Signaling -0.2013 0.0000057473730640953725 Scatter Plot
Source MIF Target FN1 FN1 ECM-Receptor -0.1969 0.0000092194702677758 Scatter Plot
Target MIF Target CEACAM CEACAM Cell-Cell Contact -0.1841 0.00003430078460769932 Scatter Plot
Source MIF Source LAMININ LAMININ ECM-Receptor -0.1841 0.00003432743410038702 Scatter Plot
Source MIF Source IL2 IL2 Secreted Signaling -0.1838 0.000035620566959834937 Scatter Plot
Source MIF Target NOTCH NOTCH Cell-Cell Contact -0.1832 0.0000378634105100972 Scatter Plot
Source MIF Target BST2 BST2 Cell-Cell Contact -0.1818 0.00004329148683171352 Scatter Plot
Source MIF Target LAIR1 LAIR1 Cell-Cell Contact -0.1818 0.00004329148683171368 Scatter Plot
Source MIF Target EPHB EPHB Cell-Cell Contact -0.1813 0.000045295475296962425 Scatter Plot
Source MIF Target OSM OSM Secreted Signaling -0.1806 0.00004853853409836245 Scatter Plot
Source MIF Source CCL CCL Secreted Signaling -0.1782 0.00006176598500554108 Scatter Plot
Source MIF Target VEGF VEGF Secreted Signaling -0.1756 0.00007919625016457157 Scatter Plot
Source MIF Target NODAL NODAL Secreted Signaling -0.1724 0.0001072954321165 Scatter Plot
Source MIF Source VCAM VCAM Cell-Cell Contact -0.1678 0.0001629090765939 Scatter Plot
Source MIF Target GDF GDF Secreted Signaling -0.1651 0.000208790288796 Scatter Plot
Source MIF Target VWF VWF ECM-Receptor -0.1634 0.0002441495445594 Scatter Plot
Source MIF Target COLLAGEN COLLAGEN ECM-Receptor -0.1625 0.000263765758387 Scatter Plot
Source MIF Source NT NT Secreted Signaling -0.1591 0.0003564661825814 Scatter Plot
Source MIF Target VTN VTN ECM-Receptor -0.1562 0.0004540435750688 Scatter Plot
Source MIF Source CD1D2 CD1D2 Cell-Cell Contact -0.1557 0.0004738960730137 Scatter Plot
Source MIF Target ACTIVIN ACTIVIN Secreted Signaling -0.1534 0.0005788974660752 Scatter Plot
Source MIF Target RANKL RANKL Secreted Signaling -0.1525 0.0006227791081325 Scatter Plot
Source MIF Source CXCL CXCL Secreted Signaling -0.1479 0.0009088169382629 Scatter Plot
Source MIF Target CD34 CD34 Cell-Cell Contact -0.1479 0.0009092326283045 Scatter Plot
Source MIF Target SPP1 SPP1 Secreted Signaling -0.1441 0.001228874513622 Scatter Plot
Target MIF Target CCL CCL Secreted Signaling -0.1426 0.0013849418709312 Scatter Plot
Source MIF Source CSF CSF Secreted Signaling -0.1398 0.0017247310083587 Scatter Plot
Source MIF Target SEMA6 SEMA6 Cell-Cell Contact -0.1398 0.0017287095241603 Scatter Plot
Source MIF Target SELE SELE Cell-Cell Contact -0.1395 0.0017687901235618 Scatter Plot
Source MIF Target SEMA5 SEMA5 Cell-Cell Contact -0.1337 0.0027299200522728 Scatter Plot
Source MIF Target CEACAM CEACAM Cell-Cell Contact -0.1300 0.0035790474129829 Scatter Plot
Source MIF Source LCK LCK Cell-Cell Contact -0.1258 0.0048291733049447 Scatter Plot
Source MIF Target CSPG4 CSPG4 Cell-Cell Contact -0.1255 0.0049566736709662 Scatter Plot
Target MIF Target IFN-II IFN-II Secreted Signaling -0.1247 0.0052405227259197 Scatter Plot
Source MIF Target SEMA4 SEMA4 Cell-Cell Contact -0.1226 0.0060358000233066 Scatter Plot
Source MIF Target VISFATIN VISFATIN Secreted Signaling -0.1119 0.0123139246713031 Scatter Plot
Source MIF Target AGT AGT Secreted Signaling -0.0970 0.0301005365899168 Scatter Plot
Source MIF Target PECAM1 PECAM1 Cell-Cell Contact -0.0965 0.031040630428615 Scatter Plot

Cells that are targets of MIF from HSCs*

Cells that are source of MIF to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.