Pathway: SEMA6

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Cell-Cell Contact

Details on the SEMA6 pathway:

Specificity Index HSPC as target: 0.697
HSPC as source: 0.354

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the SEMA6 pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Source SEMA6 Source MK MK Secreted Signaling 0.0995 0.0260255347519426 Scatter Plot
Target SEMA6 Target GAS GAS Secreted Signaling 0.0996 0.0260092053859045 Scatter Plot
Source SEMA6 Source LIFR LIFR Secreted Signaling 0.0996 0.0258852007607688 Scatter Plot
Source SEMA6 Source RANKL RANKL Secreted Signaling 0.1037 0.0204272291242009 Scatter Plot
Target SEMA6 Source OSM OSM Secreted Signaling 0.1070 0.0166487179559475 Scatter Plot
Source SEMA6 Source WNT WNT Secreted Signaling 0.1071 0.0165481117768051 Scatter Plot
Target SEMA6 Source ncWNT ncWNT Secreted Signaling 0.1187 0.0078962037998883 Scatter Plot
Target SEMA6 Source GDF GDF Secreted Signaling 0.1273 0.0043536560722395 Scatter Plot
Target SEMA6 Source PTN PTN Secreted Signaling 0.1283 0.0040507431507169 Scatter Plot
Source SEMA6 Source SEMA4 SEMA4 Cell-Cell Contact 0.1328 0.0029228918551414 Scatter Plot
Target SEMA6 Source IL16 IL16 Secreted Signaling 0.1348 0.0025302989916081 Scatter Plot
Source SEMA6 Source TWEAK TWEAK Secreted Signaling 0.1366 0.0021981209821199 Scatter Plot
Target SEMA6 Source CD39 CD39 Cell-Cell Contact 0.1391 0.0018280257639152 Scatter Plot
Target SEMA6 Source AGRN AGRN ECM-Receptor 0.1405 0.0016342079401153 Scatter Plot
Target SEMA6 Source CD1D2 CD1D2 Cell-Cell Contact 0.1438 0.001259159299653 Scatter Plot
Source SEMA6 Source IL6 IL6 Secreted Signaling 0.1459 0.0010649077159281 Scatter Plot
Source SEMA6 Source APELIN APELIN Secreted Signaling 0.1461 0.0010510602797577 Scatter Plot
Target SEMA6 Source APELIN APELIN Secreted Signaling 0.1569 0.0004275076056682 Scatter Plot
Target SEMA6 Source CD45 CD45 Cell-Cell Contact 0.1642 0.0002262194024301 Scatter Plot
Target SEMA6 Target EPHA EPHA Cell-Cell Contact 0.1665 0.0001833360308737 Scatter Plot
Target SEMA6 Source IL6 IL6 Secreted Signaling 0.1675 0.0001681398212904 Scatter Plot
Target SEMA6 Target SPP1 SPP1 Secreted Signaling 0.1689 0.0001472571663387 Scatter Plot
Target SEMA6 Source WNT WNT Secreted Signaling 0.1711 0.0001206854928831 Scatter Plot
Target SEMA6 Target NCAM NCAM Cell-Cell Contact 0.1727 0.0001034460722582 Scatter Plot
Target SEMA6 Source MK MK Secreted Signaling 0.1773 0.00006728804952757174 Scatter Plot
Target SEMA6 Source THY1 THY1 Cell-Cell Contact 0.1836 0.0000362233520001483 Scatter Plot
Target SEMA6 Source GP1BA GP1BA Cell-Cell Contact 0.1853 0.000030589507488221566 Scatter Plot
Target SEMA6 Source CSF CSF Secreted Signaling 0.1875 0.000024355373879856792 Scatter Plot
Target SEMA6 Source VCAM VCAM Cell-Cell Contact 0.1910 0.000017117066485422506 Scatter Plot
Target SEMA6 Source NOTCH NOTCH Cell-Cell Contact 0.1948 0.00001143579239579758 Scatter Plot
Target SEMA6 Source CXCL CXCL Secreted Signaling 0.1962 0.000009934238952925213 Scatter Plot
Target SEMA6 Source CCL CCL Secreted Signaling 0.1975 0.000008583784987308834 Scatter Plot
Source SEMA6 Source LIGHT LIGHT Secreted Signaling 0.1989 0.000007392455831307951 Scatter Plot
Target SEMA6 Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.2022 0.000005207587539421033 Scatter Plot
Target SEMA6 Source ANGPTL ANGPTL Secreted Signaling 0.2024 0.0000050547209111792815 Scatter Plot
Target SEMA6 Source VEGF VEGF Secreted Signaling 0.2049 0.000003863292369132279 Scatter Plot
Target SEMA6 Source NT NT Secreted Signaling 0.2072 0.000002970795599949699 Scatter Plot
Target SEMA6 Source LIGHT LIGHT Secreted Signaling 0.2081 0.000002687598876516456 Scatter Plot
Target SEMA6 Source CD46 CD46 Cell-Cell Contact 0.2082 0.0000026582389303737827 Scatter Plot
Target SEMA6 Source SEMA3 SEMA3 Secreted Signaling 0.2123 0.0000016641677896293466 Scatter Plot
Target SEMA6 Source CD86 CD86 Cell-Cell Contact 0.2128 0.0000015817525775780882 Scatter Plot
Target SEMA6 Target ANGPTL ANGPTL Secreted Signaling 0.2177 0.0000008889675901179728 Scatter Plot
Target SEMA6 Source IL2 IL2 Secreted Signaling 0.2229 0.0000004772112651744248 Scatter Plot
Target SEMA6 Source LAMININ LAMININ ECM-Receptor 0.2273 0.00000027826349406843224 Scatter Plot
Target SEMA6 Source ICAM ICAM Cell-Cell Contact 0.2303 0.00000019077813629209466 Scatter Plot
Target SEMA6 Source RANKL RANKL Secreted Signaling 0.2305 0.0000001875173722824483 Scatter Plot
Target SEMA6 Source PROS PROS Secreted Signaling 0.2310 0.0000001758796008909788 Scatter Plot
Target SEMA6 Target THBS THBS ECM-Receptor 0.2325 0.00000014490029499042646 Scatter Plot
Target SEMA6 Target CSPG4 CSPG4 Cell-Cell Contact 0.2336 0.00000012672730426235166 Scatter Plot
Target SEMA6 Source PSAP PSAP Secreted Signaling 0.2532 0.00000000944041833570986 Scatter Plot
Target SEMA6 Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2537 0.000000008802624258090597 Scatter Plot
Target SEMA6 Target MK MK Secreted Signaling 0.2544 0.000000007893925255765149 Scatter Plot
Target SEMA6 Source FLT3 FLT3 Secreted Signaling 0.2635 0.0000000021854024937247083 Scatter Plot
Target SEMA6 Target SLURP SLURP Secreted Signaling 0.2649 0.0000000017859255812361691 Scatter Plot
Target SEMA6 Source EPHB EPHB Cell-Cell Contact 0.2662 0.000000001483780850665266 Scatter Plot
Target SEMA6 Target SEMA7 SEMA7 Cell-Cell Contact 0.2668 0.000000001344258480466311 Scatter Plot
Target SEMA6 Source CADM CADM Cell-Cell Contact 0.2866 0.0000000000651899721372209 Scatter Plot
Target SEMA6 Source LCK LCK Cell-Cell Contact 0.2885 0.00000000004880085476743183 Scatter Plot
Target SEMA6 Source IGF IGF Secreted Signaling 0.2952 0.0000000000163037442139893 Scatter Plot
Target SEMA6 Source CX3C CX3C Secreted Signaling 0.2957 0.000000000015171554998697734 Scatter Plot
Target SEMA6 Target KIT KIT Secreted Signaling 0.2970 0.000000000012219599278382504 Scatter Plot
Target SEMA6 Target BMP BMP Secreted Signaling 0.2979 0.000000000010551128730057443 Scatter Plot
Target SEMA6 Source LIFR LIFR Secreted Signaling 0.2992 0.000000000008452087350259443 Scatter Plot
Target SEMA6 Target VWF VWF ECM-Receptor 0.3004 0.000000000006927845298841162 Scatter Plot
Target SEMA6 Target ACTIVIN ACTIVIN Secreted Signaling 0.3044 0.0000000000035129233729838538 Scatter Plot
Target SEMA6 Target GDF GDF Secreted Signaling 0.3081 0.000000000001850047428282131 Scatter Plot
Target SEMA6 Source BST2 BST2 Cell-Cell Contact 0.3099 0.0000000000013634001739461076 Scatter Plot
Target SEMA6 Target TENASCIN TENASCIN ECM-Receptor 0.3105 0.0000000000012237222701340832 Scatter Plot
Target SEMA6 Target IGF IGF Secreted Signaling 0.3122 0.0000000000009113639828439457 Scatter Plot
Target SEMA6 Source PDGF PDGF Secreted Signaling 0.3125 0.0000000000008606287184971649 Scatter Plot
Target SEMA6 Source IL7 IL7 Secreted Signaling 0.3135 0.000000000000729504986601208 Scatter Plot
Target SEMA6 Target BSP BSP ECM-Receptor 0.3148 0.0000000000005719239700946257 Scatter Plot
Target SEMA6 Source SEMA7 SEMA7 Cell-Cell Contact 0.3150 0.0000000000005526687002809971 Scatter Plot
Target SEMA6 Source COLLAGEN COLLAGEN ECM-Receptor 0.3212 0.00000000000018261474987124806 Scatter Plot
Target SEMA6 Source TWEAK TWEAK Secreted Signaling 0.3275 0.0000000000000574725067146508 Scatter Plot
Target SEMA6 Target CD39 CD39 Cell-Cell Contact 0.3317 0.000000000000026099575665198402 Scatter Plot
Target SEMA6 Source ESAM ESAM Cell-Cell Contact 0.3432 0.000000000000002881606181971576 Scatter Plot
Target SEMA6 Target FGF FGF Secreted Signaling 0.3449 0.0000000000000020681657821697613 Scatter Plot
Target SEMA6 Target MIF MIF Secreted Signaling 0.3515 0.0000000000000005426266409916696 Scatter Plot
Target SEMA6 Source ANGPT ANGPT Secreted Signaling 0.3551 0.00000000000000026075852394614547 Scatter Plot
Target SEMA6 Source MHC-I MHC-I Cell-Cell Contact 0.3616 0.0000000000000000678376757139582 Scatter Plot
Target SEMA6 Source MHC-II MHC-II Cell-Cell Contact 0.3656 0.000000000000000029290173362765016 Scatter Plot
Target SEMA6 Source GAS GAS Secreted Signaling 0.3678 0.00000000000000001826934785760375 Scatter Plot
Target SEMA6 Source BMP BMP Secreted Signaling 0.3685 0.000000000000000015587299674320057 Scatter Plot
Target SEMA6 Source CDH CDH Cell-Cell Contact 0.3843 0.0000000000000000004762389824504436 Scatter Plot
Target SEMA6 Source JAM JAM Cell-Cell Contact 0.4111 0.0000000000000000000008239079570567723 Scatter Plot
Target SEMA6 Target WNT WNT Secreted Signaling 0.4638 0.0000000000000000000000000004787775020478069 Scatter Plot
Target SEMA6 Source CD52 CD52 Cell-Cell Contact -0.3372 0.000000000000009263258685143372 Scatter Plot
Target SEMA6 Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.3188 0.00000000000028049293980661205 Scatter Plot
Target SEMA6 Source SELL SELL Cell-Cell Contact -0.2963 0.000000000013563367690714318 Scatter Plot
Target SEMA6 Source SEMA4 SEMA4 Cell-Cell Contact -0.2469 0.000000022115821231928103 Scatter Plot
Target SEMA6 Source PARs PARs Secreted Signaling -0.2363 0.00000009014904094727805 Scatter Plot
Target SEMA6 Source COMPLEMENT COMPLEMENT Secreted Signaling -0.2225 0.0000005000182399069113 Scatter Plot
Target SEMA6 Source TGFb TGFb Secreted Signaling -0.2060 0.000003412618786053673 Scatter Plot
Target SEMA6 Source VISTA VISTA Cell-Cell Contact -0.2016 0.000005511131590590593 Scatter Plot
Target SEMA6 Source CCL CCL Secreted Signaling -0.1978 0.000008311138987392366 Scatter Plot
Target SEMA6 Target CXCL CXCL Secreted Signaling -0.1941 0.000012402133240551134 Scatter Plot
Target SEMA6 Source ANNEXIN ANNEXIN Secreted Signaling -0.1696 0.0001380960257494 Scatter Plot
Target SEMA6 Source CLEC CLEC Cell-Cell Contact -0.1689 0.0001474454002121 Scatter Plot
Target SEMA6 Target IL17 IL17 Secreted Signaling -0.1551 0.000502249633645 Scatter Plot
Target SEMA6 Source SPP1 SPP1 Secreted Signaling -0.1445 0.0011907858128229 Scatter Plot
Target SEMA6 Source MIF MIF Secreted Signaling -0.1398 0.0017287095241603 Scatter Plot
Target SEMA6 Source SELPLG SELPLG Cell-Cell Contact -0.1347 0.002543514766647 Scatter Plot
Source SEMA6 Source FGF FGF Secreted Signaling -0.1265 0.0046145911855177 Scatter Plot
Target SEMA6 Source NKG2D NKG2D Cell-Cell Contact -0.1215 0.0065352571862799 Scatter Plot
Source SEMA6 Source GALECTIN GALECTIN Secreted Signaling -0.1197 0.0073519527282378 Scatter Plot
Target SEMA6 Source NCAM NCAM Cell-Cell Contact -0.1141 0.0106561077827867 Scatter Plot
Target SEMA6 Source ANGPTL ANGPTL Secreted Signaling -0.1117 0.0124820822523921 Scatter Plot
Source SEMA6 Source VCAM VCAM Cell-Cell Contact -0.1085 0.0151968343655966 Scatter Plot
Target SEMA6 Source LAIR1 LAIR1 Cell-Cell Contact -0.1062 0.0175692317969339 Scatter Plot
Source SEMA6 Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.0981 0.0283562949752528 Scatter Plot
Source SEMA6 Target LAMININ LAMININ ECM-Receptor 0.0991 0.026708615205239 Scatter Plot
Source SEMA6 Target GDF GDF Secreted Signaling 0.1006 0.0244806569005395 Scatter Plot
Source SEMA6 Source ICAM ICAM Cell-Cell Contact 0.1012 0.0236983686859051 Scatter Plot
Source SEMA6 Target TGFb TGFb Secreted Signaling 0.1028 0.0215486996872204 Scatter Plot
Source SEMA6 Target IFN-II IFN-II Secreted Signaling 0.1046 0.0193379112428514 Scatter Plot
Source SEMA6 Target ANGPTL ANGPTL Secreted Signaling 0.1048 0.0190784772564107 Scatter Plot
Target SEMA6 Target THY1 THY1 Cell-Cell Contact 0.1063 0.0173975715949783 Scatter Plot
Source SEMA6 Target SEMA4 SEMA4 Cell-Cell Contact 0.1073 0.016366437739141 Scatter Plot
Source SEMA6 Target CD200 CD200 Cell-Cell Contact 0.1074 0.0162699989370944 Scatter Plot
Source SEMA6 Source CADM CADM Cell-Cell Contact 0.1076 0.0161142164470606 Scatter Plot
Source SEMA6 Target CADM CADM Cell-Cell Contact 0.1076 0.0161142164470606 Scatter Plot
Source SEMA6 Target SLURP SLURP Secreted Signaling 0.1099 0.0139783445550259 Scatter Plot
Source SEMA6 Target NRG NRG Secreted Signaling 0.1108 0.0131601393870914 Scatter Plot
Source SEMA6 Target WNT WNT Secreted Signaling 0.1111 0.012888935106089 Scatter Plot
Source SEMA6 Target VTN VTN ECM-Receptor 0.1123 0.0119501129796451 Scatter Plot
Target SEMA6 Target CD23 CD23 Cell-Cell Contact 0.1124 0.0119078495152153 Scatter Plot
Source SEMA6 Target FGF FGF Secreted Signaling 0.1140 0.0107204803709316 Scatter Plot
Source SEMA6 Target TENASCIN TENASCIN ECM-Receptor 0.1142 0.0105901092882112 Scatter Plot
Source SEMA6 Target DMP1 DMP1 ECM-Receptor 0.1217 0.0064381859169211 Scatter Plot
Source SEMA6 Target THBS THBS ECM-Receptor 0.1220 0.0063202829706492 Scatter Plot
Source SEMA6 Target COLLAGEN COLLAGEN ECM-Receptor 0.1224 0.0061214722383962 Scatter Plot
Source SEMA6 Source MHC-II MHC-II Cell-Cell Contact 0.1233 0.0057703188461725 Scatter Plot
Source SEMA6 Target EPHB EPHB Cell-Cell Contact 0.1240 0.0055081743556942 Scatter Plot
Source SEMA6 Target ESAM ESAM Cell-Cell Contact 0.1244 0.0053479075740632 Scatter Plot
Source SEMA6 Source ESAM ESAM Cell-Cell Contact 0.1244 0.0053479075740632 Scatter Plot
Target SEMA6 Target NOTCH NOTCH Cell-Cell Contact 0.1255 0.0049608465268759 Scatter Plot
Source SEMA6 Source SEMA7 SEMA7 Cell-Cell Contact 0.1256 0.0049051382505139 Scatter Plot
Source SEMA6 Target NPR2 NPR2 Secreted Signaling 0.1259 0.0048182264426499 Scatter Plot
Source SEMA6 Target ACTIVIN ACTIVIN Secreted Signaling 0.1265 0.0046029243565464 Scatter Plot
Source SEMA6 Source FN1 FN1 ECM-Receptor 0.1271 0.0044312715161958 Scatter Plot
Source SEMA6 Source LAIR1 LAIR1 Cell-Cell Contact 0.1276 0.0042724093328303 Scatter Plot
Source SEMA6 Source FLT3 FLT3 Secreted Signaling 0.1281 0.0041104663017644 Scatter Plot
Source SEMA6 Source CX3C CX3C Secreted Signaling 0.1293 0.0037732085172375 Scatter Plot
Source SEMA6 Source ANGPTL ANGPTL Secreted Signaling 0.1306 0.0034478916209551 Scatter Plot
Source SEMA6 Source IL2 IL2 Secreted Signaling 0.1314 0.00323588951936 Scatter Plot
Source SEMA6 Source SEMA4 SEMA4 Cell-Cell Contact 0.1328 0.0029228918551414 Scatter Plot
Source SEMA6 Target APP APP Cell-Cell Contact 0.1339 0.0027029582477994 Scatter Plot
Source SEMA6 Target CSPG4 CSPG4 Cell-Cell Contact 0.1359 0.0023222923858131 Scatter Plot
Source SEMA6 Source CD39 CD39 Cell-Cell Contact 0.1372 0.0021041130275229 Scatter Plot
Source SEMA6 Target CD86 CD86 Cell-Cell Contact 0.1372 0.002101490656398 Scatter Plot
Target SEMA6 Target CD45 CD45 Cell-Cell Contact 0.1374 0.0020733178790806 Scatter Plot
Source SEMA6 Source NOTCH NOTCH Cell-Cell Contact 0.1377 0.002022578825322 Scatter Plot
Source SEMA6 Target VEGF VEGF Secreted Signaling 0.1383 0.0019310744910327 Scatter Plot
Source SEMA6 Target BSP BSP ECM-Receptor 0.1389 0.0018536486937147 Scatter Plot
Source SEMA6 Source IL7 IL7 Secreted Signaling 0.1391 0.0018226159922788 Scatter Plot
Source SEMA6 Target VISFATIN VISFATIN Secreted Signaling 0.1404 0.0016484057459414 Scatter Plot
Source SEMA6 Target NODAL NODAL Secreted Signaling 0.1418 0.0014798823516534 Scatter Plot
Source SEMA6 Target CSF CSF Secreted Signaling 0.1418 0.0014795291824703 Scatter Plot
Source SEMA6 Target MIF MIF Secreted Signaling 0.1421 0.0014389710634579 Scatter Plot
Target SEMA6 Target RANKL RANKL Secreted Signaling 0.1431 0.0013325004870143 Scatter Plot
Source SEMA6 Source GAS GAS Secreted Signaling 0.1433 0.0013183020594141 Scatter Plot
Source SEMA6 Target PERIOSTIN PERIOSTIN Secreted Signaling 0.1453 0.0011183823287864 Scatter Plot
Source SEMA6 Target SEMA3 SEMA3 Secreted Signaling 0.1463 0.0010381950511119 Scatter Plot
Source SEMA6 Target CCL CCL Secreted Signaling 0.1473 0.0009577401419853 Scatter Plot
Source SEMA6 Target OSM OSM Secreted Signaling 0.1499 0.0007749019069699 Scatter Plot
Source SEMA6 Source PDGF PDGF Secreted Signaling 0.1504 0.0007437673346927 Scatter Plot
Source SEMA6 Source CXCL CXCL Secreted Signaling 0.1559 0.0004656143602699 Scatter Plot
Source SEMA6 Target CDH CDH Cell-Cell Contact 0.1587 0.0003671547883764 Scatter Plot
Source SEMA6 Source CDH CDH Cell-Cell Contact 0.1587 0.0003671547883764 Scatter Plot
Source SEMA6 Source PROS PROS Secreted Signaling 0.1610 0.0003000426442435 Scatter Plot
Target SEMA6 Target CD22 CD22 Cell-Cell Contact 0.1642 0.0002262194024301 Scatter Plot
Source SEMA6 Target CD34 CD34 Cell-Cell Contact 0.1656 0.0001993242001086 Scatter Plot
Source SEMA6 Target EPHA EPHA Cell-Cell Contact 0.1657 0.0001976589531695 Scatter Plot
Target SEMA6 Target COLLAGEN COLLAGEN ECM-Receptor 0.1682 0.0001579860656653 Scatter Plot
Source SEMA6 Source LAMININ LAMININ ECM-Receptor 0.1720 0.0001110638828911 Scatter Plot
Source SEMA6 Target SELPLG SELPLG Cell-Cell Contact 0.1726 0.0001045152481049 Scatter Plot
Source SEMA6 Source JAM JAM Cell-Cell Contact 0.1727 0.00010435648156 Scatter Plot
Source SEMA6 Target BMP BMP Secreted Signaling 0.1749 0.00008451447292769363 Scatter Plot
Target SEMA6 Target NODAL NODAL Secreted Signaling 0.1771 0.00006819059806043768 Scatter Plot
Source SEMA6 Target JAM JAM Cell-Cell Contact 0.1806 0.00004893371195848304 Scatter Plot
Target SEMA6 Target FN1 FN1 ECM-Receptor 0.1817 0.00004372216405277024 Scatter Plot
Source SEMA6 Source PSAP PSAP Secreted Signaling 0.1866 0.000026780922499174564 Scatter Plot
Target SEMA6 Target SPP1 SPP1 Secreted Signaling 0.1903 0.00001843169150526767 Scatter Plot
Source SEMA6 Target BAFF BAFF Secreted Signaling 0.1981 0.000008099701358193114 Scatter Plot
Source SEMA6 Source APP APP Cell-Cell Contact 0.2008 0.000006022367495325149 Scatter Plot
Target SEMA6 Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2022 0.000005198456985733155 Scatter Plot
Target SEMA6 Target OSM OSM Secreted Signaling 0.2052 0.000003716863457660674 Scatter Plot
Source SEMA6 Source NT NT Secreted Signaling 0.2077 0.000002825654441170501 Scatter Plot
Source SEMA6 Source CD46 CD46 Cell-Cell Contact 0.2090 0.000002441678776736354 Scatter Plot
Target SEMA6 Target BAFF BAFF Secreted Signaling 0.2098 0.0000022069722726005697 Scatter Plot
Source SEMA6 Target IL6 IL6 Secreted Signaling 0.2110 0.00000192529810379044 Scatter Plot
Target SEMA6 Target IL6 IL6 Secreted Signaling 0.2196 0.0000007071413281221725 Scatter Plot
Source SEMA6 Source BMP BMP Secreted Signaling 0.2242 0.0000004068584380720549 Scatter Plot
Source SEMA6 Source BST2 BST2 Cell-Cell Contact 0.2260 0.00000032641900080344564 Scatter Plot
Source SEMA6 Source CCL CCL Secreted Signaling 0.2363 0.00000008989885165993714 Scatter Plot
Target SEMA6 Target PTN PTN Secreted Signaling 0.2463 0.00000002395225794118272 Scatter Plot
Target SEMA6 Target LAMININ LAMININ ECM-Receptor 0.2480 0.000000019212193005346802 Scatter Plot
Target SEMA6 Target PARs PARs Secreted Signaling 0.2502 0.000000014230450147961969 Scatter Plot
Target SEMA6 Target ANGPT ANGPT Secreted Signaling 0.2587 0.000000004345230441413602 Scatter Plot
Target SEMA6 Target VISFATIN VISFATIN Secreted Signaling 0.2788 0.00000000022365758993500056 Scatter Plot
Target SEMA6 Target CD200 CD200 Cell-Cell Contact 0.2812 0.00000000015449605743502201 Scatter Plot
Target SEMA6 Target CADM CADM Cell-Cell Contact 0.2866 0.0000000000651899721372209 Scatter Plot
Target SEMA6 Target VTN VTN ECM-Receptor 0.2899 0.00000000003901401409613239 Scatter Plot
Target SEMA6 Target EPHB EPHB Cell-Cell Contact 0.2926 0.000000000025005235376886908 Scatter Plot
Target SEMA6 Target AGT AGT Secreted Signaling 0.2981 0.000000000010196358078484443 Scatter Plot
Target SEMA6 Target NPR2 NPR2 Secreted Signaling 0.2992 0.000000000008473200054234493 Scatter Plot
Target SEMA6 Target SEMA7 SEMA7 Cell-Cell Contact 0.3013 0.000000000005952173983866593 Scatter Plot
Target SEMA6 Target NRG NRG Secreted Signaling 0.3074 0.000000000002089654909181235 Scatter Plot
Target SEMA6 Target TGFb TGFb Secreted Signaling 0.3146 0.0000000000006015973988916514 Scatter Plot
Target SEMA6 Target PERIOSTIN PERIOSTIN Secreted Signaling 0.3169 0.00000000000040018740783623893 Scatter Plot
Target SEMA6 Target DMP1 DMP1 ECM-Receptor 0.3177 0.0000000000003440557064452037 Scatter Plot
Target SEMA6 Target APP APP Cell-Cell Contact 0.3319 0.000000000000025519607912649516 Scatter Plot
Target SEMA6 Target ESAM ESAM Cell-Cell Contact 0.3432 0.000000000000002881606181971576 Scatter Plot
Target SEMA6 Target JAM JAM Cell-Cell Contact 0.3486 0.0000000000000009872213664344332 Scatter Plot
Target SEMA6 Target CDH CDH Cell-Cell Contact 0.3843 0.0000000000000000004762389824504436 Scatter Plot
Target SEMA6 Target SLURP SLURP Secreted Signaling 0.3876 0.0000000000000000002246513641521105 Scatter Plot
Target SEMA6 Target CD34 CD34 Cell-Cell Contact 0.3880 0.00000000000000000020436382306889693 Scatter Plot
Target SEMA6 Target ncWNT ncWNT Secreted Signaling 0.4359 0.0000000000000000000000013094625378285014 Scatter Plot
Target SEMA6 Target ICAM ICAM Cell-Cell Contact -0.3031 0.0000000000043532256411692346 Scatter Plot
Target SEMA6 Target CD52 CD52 Cell-Cell Contact -0.2587 0.000000004362870116106531 Scatter Plot
Target SEMA6 Target IFN-II IFN-II Secreted Signaling -0.2367 0.00000008508080906138224 Scatter Plot
Target SEMA6 Target CEACAM CEACAM Cell-Cell Contact -0.1942 0.0000122546588011305 Scatter Plot
Target SEMA6 Target VCAM VCAM Cell-Cell Contact -0.1851 0.00003107170984768352 Scatter Plot
Target SEMA6 Target CSF CSF Secreted Signaling -0.1832 0.000037771319636107805 Scatter Plot
Target SEMA6 Target CCL CCL Secreted Signaling -0.1818 0.00004328234384696139 Scatter Plot
Target SEMA6 Target CLEC CLEC Cell-Cell Contact -0.1810 0.000047031239227130026 Scatter Plot
Target SEMA6 Target COLLAGEN COLLAGEN ECM-Receptor -0.1203 0.0070737988186453 Scatter Plot
Target SEMA6 Target ANNEXIN ANNEXIN Secreted Signaling -0.1166 0.0090801664412281 Scatter Plot
Source SEMA6 Source BAFF BAFF Secreted Signaling -0.1151 0.0100240447903709 Scatter Plot
Target SEMA6 Target GRN GRN Secreted Signaling -0.1136 0.0110367690502711 Scatter Plot
Source SEMA6 Target ANNEXIN ANNEXIN Secreted Signaling -0.1070 0.0166996207615092 Scatter Plot

Cells that are targets of SEMA6 from HSCs*

Cells that are source of SEMA6 to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.