Pathway: ANGPT

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Secreted Signaling

Details on the ANGPT pathway:

Specificity Index HSPC as target: 0.119
HSPC as source: 0.952

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the ANGPT pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target ANGPT Source GALECTIN GALECTIN Secreted Signaling 0.1135 0.0110852638998175 Scatter Plot
Target ANGPT Source APELIN APELIN Secreted Signaling 0.1146 0.0103603138414194 Scatter Plot
Target ANGPT Target CXCL CXCL Secreted Signaling 0.1295 0.003726241256238 Scatter Plot
Source ANGPT Source ncWNT ncWNT Secreted Signaling 0.1373 0.0020914725082983 Scatter Plot
Target ANGPT Source ANGPTL ANGPTL Secreted Signaling 0.1410 0.0015710693937073 Scatter Plot
Target ANGPT Source ncWNT ncWNT Secreted Signaling 0.1446 0.0011851493112451 Scatter Plot
Target ANGPT Target NOTCH NOTCH Cell-Cell Contact 0.1523 0.0006328485696785 Scatter Plot
Target ANGPT Target RANKL RANKL Secreted Signaling 0.1530 0.0005976619112372 Scatter Plot
Target ANGPT Target EPHA EPHA Cell-Cell Contact 0.1559 0.0004661860538586 Scatter Plot
Target ANGPT Source THBS THBS ECM-Receptor 0.1621 0.0002732674612513 Scatter Plot
Target ANGPT Source WNT WNT Secreted Signaling 0.1805 0.000049404080343439146 Scatter Plot
Source ANGPT Source WNT WNT Secreted Signaling 0.1839 0.00003524490725030534 Scatter Plot
Target ANGPT Source GDF GDF Secreted Signaling 0.1868 0.000026391268914967905 Scatter Plot
Target ANGPT Source PTN PTN Secreted Signaling 0.1942 0.00001223394089106975 Scatter Plot
Target ANGPT Target NCAM NCAM Cell-Cell Contact 0.1967 0.000009351488626492272 Scatter Plot
Target ANGPT Target VEGF VEGF Secreted Signaling 0.1969 0.000009165234637980284 Scatter Plot
Source ANGPT Source APELIN APELIN Secreted Signaling 0.2018 0.000005436750738318654 Scatter Plot
Target ANGPT Target PTN PTN Secreted Signaling 0.2037 0.000004387702213697908 Scatter Plot
Target ANGPT Target AGT AGT Secreted Signaling 0.2062 0.0000033467365266988117 Scatter Plot
Target ANGPT Source IL2 IL2 Secreted Signaling 0.2100 0.0000021566777687554296 Scatter Plot
Target ANGPT Source CADM CADM Cell-Cell Contact 0.2116 0.0000018151146157405492 Scatter Plot
Target ANGPT Target CADM CADM Cell-Cell Contact 0.2116 0.0000018151146157405492 Scatter Plot
Target ANGPT Source FGF FGF Secreted Signaling 0.2173 0.0000009317645368192996 Scatter Plot
Target ANGPT Source CD39 CD39 Cell-Cell Contact 0.2282 0.00000024938118526793885 Scatter Plot
Target ANGPT Target GDF GDF Secreted Signaling 0.2302 0.00000019441623228219089 Scatter Plot
Target ANGPT Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2345 0.0000001128377752021039 Scatter Plot
Target ANGPT Source IL16 IL16 Secreted Signaling 0.2401 0.0000000547524232159762 Scatter Plot
Target ANGPT Source CD1D2 CD1D2 Cell-Cell Contact 0.2435 0.000000035188073848696246 Scatter Plot
Target ANGPT Source SEMA3 SEMA3 Secreted Signaling 0.2442 0.000000031689373948267655 Scatter Plot
Target ANGPT Source CD46 CD46 Cell-Cell Contact 0.2447 0.0000000298281561969043 Scatter Plot
Target ANGPT Source VEGF VEGF Secreted Signaling 0.2567 0.0000000057270288120673325 Scatter Plot
Target ANGPT Source CCL CCL Secreted Signaling 0.2576 0.000000005045262975708591 Scatter Plot
Target ANGPT Target SEMA6 SEMA6 Cell-Cell Contact 0.2587 0.000000004345230441413602 Scatter Plot
Target ANGPT Source GP1BA GP1BA Cell-Cell Contact 0.2675 0.0000000012195709213032476 Scatter Plot
Target ANGPT Source NT NT Secreted Signaling 0.2697 0.0000000008825583002314687 Scatter Plot
Target ANGPT Source THY1 THY1 Cell-Cell Contact 0.2702 0.0000000008145915318599403 Scatter Plot
Target ANGPT Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.2771 0.000000000286614307061128 Scatter Plot
Target ANGPT Source LIGHT LIGHT Secreted Signaling 0.2853 0.00000000008027316644188954 Scatter Plot
Target ANGPT Source CSF CSF Secreted Signaling 0.2857 0.00000000007596733601040265 Scatter Plot
Target ANGPT Source CD86 CD86 Cell-Cell Contact 0.2967 0.000000000012703940540412334 Scatter Plot
Target ANGPT Target SEMA5 SEMA5 Cell-Cell Contact 0.2989 0.000000000008868262496943488 Scatter Plot
Target ANGPT Source PSAP PSAP Secreted Signaling 0.3124 0.0000000000008771976829750244 Scatter Plot
Target ANGPT Source LAMININ LAMININ ECM-Receptor 0.3129 0.0000000000008068385540289259 Scatter Plot
Target ANGPT Target EPHB EPHB Cell-Cell Contact 0.3258 0.00000000000007910320159149988 Scatter Plot
Target ANGPT Source IGF IGF Secreted Signaling 0.3270 0.00000000000006303334142662337 Scatter Plot
Target ANGPT Source NOTCH NOTCH Cell-Cell Contact 0.3273 0.00000000000005967296438271812 Scatter Plot
Target ANGPT Source CXCL CXCL Secreted Signaling 0.3332 0.000000000000019627153012481132 Scatter Plot
Target ANGPT Source CX3C CX3C Secreted Signaling 0.3358 0.000000000000012044517007946976 Scatter Plot
Target ANGPT Source LCK LCK Cell-Cell Contact 0.3483 0.000000000000001038027373558109 Scatter Plot
Target ANGPT Target TGFb TGFb Secreted Signaling 0.3491 0.000000000000000893740213295321 Scatter Plot
Target ANGPT Source CDH CDH Cell-Cell Contact 0.3525 0.0000000000000004481653922380513 Scatter Plot
Target ANGPT Target CDH CDH Cell-Cell Contact 0.3525 0.0000000000000004481653922380513 Scatter Plot
Target ANGPT Source BST2 BST2 Cell-Cell Contact 0.3533 0.0000000000000003802945758568484 Scatter Plot
Target ANGPT Source ICAM ICAM Cell-Cell Contact 0.3574 0.00000000000000016265019553398032 Scatter Plot
Target ANGPT Source RANKL RANKL Secreted Signaling 0.3627 0.00000000000000005406628843485096 Scatter Plot
Target ANGPT Source CD45 CD45 Cell-Cell Contact 0.3647 0.000000000000000035617022162864866 Scatter Plot
Target ANGPT Target ACTIVIN ACTIVIN Secreted Signaling 0.3708 0.000000000000000009537460386011829 Scatter Plot
Target ANGPT Source MK MK Secreted Signaling 0.3792 0.0000000000000000015247413239133942 Scatter Plot
Target ANGPT Source IL7 IL7 Secreted Signaling 0.3815 0.0000000000000000009079642154122511 Scatter Plot
Source ANGPT Source RANKL RANKL Secreted Signaling 0.3893 0.00000000000000000015060877791517725 Scatter Plot
Target ANGPT Target NPR2 NPR2 Secreted Signaling 0.3963 0.000000000000000000029554633534640584 Scatter Plot
Target ANGPT Source EPHB EPHB Cell-Cell Contact 0.3994 0.00000000000000000001428299125772678 Scatter Plot
Target ANGPT Source PROS PROS Secreted Signaling 0.4073 0.000000000000000000002081224867364105 Scatter Plot
Target ANGPT Target CD200 CD200 Cell-Cell Contact 0.4127 0.0000000000000000000005466168967534313 Scatter Plot
Target ANGPT Source FLT3 FLT3 Secreted Signaling 0.4170 0.000000000000000000000185854174487593 Scatter Plot
Target ANGPT Target BMP BMP Secreted Signaling 0.4190 0.00000000000000000000011163694814407614 Scatter Plot
Target ANGPT Target PERIOSTIN PERIOSTIN Secreted Signaling 0.4228 0.00000000000000000000004189396376028641 Scatter Plot
Target ANGPT Target MIF MIF Secreted Signaling 0.4333 0.000000000000000000000002612771194596416 Scatter Plot
Target ANGPT Target BSP BSP ECM-Receptor 0.4364 0.0000000000000000000000011336092969507926 Scatter Plot
Target ANGPT Target APP APP Cell-Cell Contact 0.4417 0.000000000000000000000000266836725601053 Scatter Plot
Target ANGPT Target KIT KIT Secreted Signaling 0.4430 0.0000000000000000000000001874457049135288 Scatter Plot
Target ANGPT Target DMP1 DMP1 ECM-Receptor 0.4477 0.00000000000000000000000005003207557789964 Scatter Plot
Target ANGPT Source GAS GAS Secreted Signaling 0.4591 0.0000000000000000000000000019456417760379344 Scatter Plot
Source ANGPT Source LAMININ LAMININ ECM-Receptor 0.4662 0.0000000000000000000000000002361748329185894 Scatter Plot
Source ANGPT Source LIGHT LIGHT Secreted Signaling 0.4700 0.00000000000000000000000000007619717589320665 Scatter Plot
Target ANGPT Target SLURP SLURP Secreted Signaling 0.4702 0.00000000000000000000000000007127993638171768 Scatter Plot
Target ANGPT Source COLLAGEN COLLAGEN ECM-Receptor 0.4709 0.00000000000000000000000000005839123078464261 Scatter Plot
Target ANGPT Source SEMA7 SEMA7 Cell-Cell Contact 0.4740 0.000000000000000000000000000022076275466031548 Scatter Plot
Target ANGPT Source PDGF PDGF Secreted Signaling 0.4835 0.0000000000000000000000000000011734505397877785 Scatter Plot
Target ANGPT Source LIFR LIFR Secreted Signaling 0.4933 0.0000000000000000000000000000000491035111030057 Scatter Plot
Target ANGPT Target ncWNT ncWNT Secreted Signaling 0.4988 0.000000000000000000000000000000008176235834370053 Scatter Plot
Target ANGPT Source TWEAK TWEAK Secreted Signaling 0.5010 0.000000000000000000000000000000003857753409054747 Scatter Plot
Target ANGPT Target WNT WNT Secreted Signaling 0.5028 0.0000000000000000000000000000000021423447146661088 Scatter Plot
Target ANGPT Target FGF FGF Secreted Signaling 0.5047 0.0000000000000000000000000000000011197713931760773 Scatter Plot
Target ANGPT Source BMP BMP Secreted Signaling 0.5054 0.0000000000000000000000000000000008713126784835644 Scatter Plot
Target ANGPT Target IGF IGF Secreted Signaling 0.5235 0.0000000000000000000000000000000000015521318074387303 Scatter Plot
Target ANGPT Source MHC-II MHC-II Cell-Cell Contact 0.5301 0.00000000000000000000000000000000000013681317181782655 Scatter Plot
Target ANGPT Target CD39 CD39 Cell-Cell Contact 0.5447 0.0000000000000000000000000000000000000005417441791337281 Scatter Plot
Target ANGPT Target VWF VWF ECM-Receptor 0.5482 0.00000000000000000000000000000000000000014137768882301146 Scatter Plot
Source ANGPT Source LIFR LIFR Secreted Signaling 0.5533 0.000000000000000000000000000000000000000018816235077416768 Scatter Plot
Target ANGPT Source JAM JAM Cell-Cell Contact 0.5860 0.000000000000000000000000000000000000000000000018447703986301528 Scatter Plot
Target ANGPT Source MHC-I MHC-I Cell-Cell Contact 0.5884 0.000000000000000000000000000000000000000000000006536279771730693 Scatter Plot
Target ANGPT Source ESAM ESAM Cell-Cell Contact 0.5992 0.00000000000000000000000000000000000000000000000004555409426381841 Scatter Plot
Target ANGPT Target ESAM ESAM Cell-Cell Contact 0.5992 0.00000000000000000000000000000000000000000000000004555409426381841 Scatter Plot
Source ANGPT Source TWEAK TWEAK Secreted Signaling 0.6300 0.000000000000000000000000000000000000000000000000000000011151190315175168 Scatter Plot
Source ANGPT Source PARs PARs Secreted Signaling -0.5101 0.00000000000000000000000000000000017383329757938322 Scatter Plot
Target ANGPT Source CD52 CD52 Cell-Cell Contact -0.4790 0.0000000000000000000000000000047373019619498245 Scatter Plot
Target ANGPT Source SELL SELL Cell-Cell Contact -0.4557 0.0000000000000000000000000052058713222595426 Scatter Plot
Target ANGPT Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.4183 0.0000000000000000000001331181568339752 Scatter Plot
Target ANGPT Source PARs PARs Secreted Signaling -0.3797 0.0000000000000000013393038683003117 Scatter Plot
Target ANGPT Source COMPLEMENT COMPLEMENT Secreted Signaling -0.3558 0.00000000000000022603570371784244 Scatter Plot
Target ANGPT Source CCL CCL Secreted Signaling -0.3175 0.00000000000035941863021123853 Scatter Plot
Target ANGPT Source SEMA4 SEMA4 Cell-Cell Contact -0.3147 0.0000000000005890503458656072 Scatter Plot
Target ANGPT Source CLEC CLEC Cell-Cell Contact -0.2829 0.0000000001171658190160411 Scatter Plot
Target ANGPT Target CSF CSF Secreted Signaling -0.2825 0.00000000012518525517002653 Scatter Plot
Target ANGPT Source VISTA VISTA Cell-Cell Contact -0.2816 0.00000000014447318692707028 Scatter Plot
Target ANGPT Target CXCL CXCL Secreted Signaling -0.2805 0.00000000017174717252288234 Scatter Plot
Target ANGPT Target VCAM VCAM Cell-Cell Contact -0.2718 0.0000000006463727370091735 Scatter Plot
Target ANGPT Source MIF MIF Secreted Signaling -0.2656 0.0000000016115989157895351 Scatter Plot
Target ANGPT Source ANGPTL ANGPTL Secreted Signaling -0.2238 0.0000004290065148879217 Scatter Plot
Target ANGPT Source TNF TNF Secreted Signaling -0.2222 0.0000005173844178677806 Scatter Plot
Source ANGPT Source ANGPTL ANGPTL Secreted Signaling -0.2178 0.0000008773709553149126 Scatter Plot
Target ANGPT Target IL17 IL17 Secreted Signaling -0.2166 0.0000010163598840442902 Scatter Plot
Target ANGPT Source TGFb TGFb Secreted Signaling -0.1805 0.00004898842501677473 Scatter Plot
Target ANGPT Source ANNEXIN ANNEXIN Secreted Signaling -0.1672 0.0001722962752607 Scatter Plot
Target ANGPT Target CEACAM CEACAM Cell-Cell Contact -0.1649 0.0002127680093539 Scatter Plot
Target ANGPT Target VEGF VEGF Secreted Signaling -0.1601 0.0003265533833148 Scatter Plot
Target ANGPT Source NKG2D NKG2D Cell-Cell Contact -0.1593 0.000349675890281 Scatter Plot
Target ANGPT Source SELPLG SELPLG Cell-Cell Contact -0.1478 0.0009157199468189 Scatter Plot
Target ANGPT Source APP APP Cell-Cell Contact -0.1468 0.0009947255470428 Scatter Plot
Target ANGPT Target SEMA3 SEMA3 Secreted Signaling -0.1423 0.00142552567426 Scatter Plot
Target ANGPT Source NCAM NCAM Cell-Cell Contact -0.1395 0.0017622804990557 Scatter Plot
Target ANGPT Source SPP1 SPP1 Secreted Signaling -0.1382 0.0019545868355469 Scatter Plot
Target ANGPT Target ANNEXIN ANNEXIN Secreted Signaling -0.1343 0.0026165776565008 Scatter Plot
Target ANGPT Source VISFATIN VISFATIN Secreted Signaling -0.1204 0.0070200948577633 Scatter Plot
Target ANGPT Source LAIR1 LAIR1 Cell-Cell Contact -0.1193 0.0075716784112595 Scatter Plot
Source ANGPT Source OSM OSM Secreted Signaling 0.1082 0.0154663247641315 Scatter Plot
Source ANGPT Target GAS GAS Secreted Signaling 0.1090 0.0147355983755121 Scatter Plot
Source ANGPT Target CD23 CD23 Cell-Cell Contact 0.1127 0.0116911165614535 Scatter Plot
Target ANGPT Target GALECTIN GALECTIN Secreted Signaling 0.1128 0.0115686331687473 Scatter Plot
Source ANGPT Source ICOS ICOS Cell-Cell Contact 0.1132 0.0112865417641376 Scatter Plot
Source ANGPT Target NCAM NCAM Cell-Cell Contact 0.1187 0.0078876393660402 Scatter Plot
Source ANGPT Target RANKL RANKL Secreted Signaling 0.1207 0.0068734667467414 Scatter Plot
Target ANGPT Target GAS GAS Secreted Signaling 0.1402 0.0016720186155552 Scatter Plot
Target ANGPT Target SEMA3 SEMA3 Secreted Signaling 0.1430 0.0013438952980836 Scatter Plot
Source ANGPT Target PDGF PDGF Secreted Signaling 0.1471 0.0009695326109443 Scatter Plot
Source ANGPT Source THBS THBS ECM-Receptor 0.1477 0.0009205270072891 Scatter Plot
Target ANGPT Target IL6 IL6 Secreted Signaling 0.1536 0.0005677680322528 Scatter Plot
Source ANGPT Target SEMA3 SEMA3 Secreted Signaling 0.1570 0.0004237530471784 Scatter Plot
Source ANGPT Target GALECTIN GALECTIN Secreted Signaling 0.1641 0.000229327868143 Scatter Plot
Source ANGPT Target TWEAK TWEAK Secreted Signaling 0.1697 0.0001370293150236 Scatter Plot
Target ANGPT Target THY1 THY1 Cell-Cell Contact 0.1809 0.00004720725114912741 Scatter Plot
Source ANGPT Target COLLAGEN COLLAGEN ECM-Receptor 0.1809 0.00004708572891680848 Scatter Plot
Target ANGPT Target CD23 CD23 Cell-Cell Contact 0.1959 0.00001021152623928832 Scatter Plot
Source ANGPT Source GALECTIN GALECTIN Secreted Signaling 0.2011 0.000005869713717730679 Scatter Plot
Source ANGPT Source APELIN APELIN Secreted Signaling 0.2017 0.000005457085708999603 Scatter Plot
Source ANGPT Source IL6 IL6 Secreted Signaling 0.2034 0.00000454451787128309 Scatter Plot
Target ANGPT Target AGT AGT Secreted Signaling 0.2062 0.000003346736526698817 Scatter Plot
Source ANGPT Source PTN PTN Secreted Signaling 0.2091 0.000002409094271796672 Scatter Plot
Target ANGPT Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2128 0.0000015734001623653687 Scatter Plot
Source ANGPT Target AGT AGT Secreted Signaling 0.2158 0.0000011136891863453493 Scatter Plot
Source ANGPT Target IL6 IL6 Secreted Signaling 0.2248 0.0000003785300094599674 Scatter Plot
Source ANGPT Source FGF FGF Secreted Signaling 0.2257 0.00000034102734324541057 Scatter Plot
Source ANGPT Target EPHA EPHA Cell-Cell Contact 0.2257 0.0000003371654989646379 Scatter Plot
Source ANGPT Source CADM CADM Cell-Cell Contact 0.2333 0.00000013078852137674676 Scatter Plot
Source ANGPT Target CADM CADM Cell-Cell Contact 0.2333 0.00000013078852137674676 Scatter Plot
Source ANGPT Target OSM OSM Secreted Signaling 0.2343 0.00000011579963232344381 Scatter Plot
Source ANGPT Source SEMA3 SEMA3 Secreted Signaling 0.2367 0.00000008466784944032512 Scatter Plot
Source ANGPT Target NOTCH NOTCH Cell-Cell Contact 0.2387 0.00000006537399682307373 Scatter Plot
Source ANGPT Source CD34 CD34 Cell-Cell Contact 0.2403 0.000000053139944313233955 Scatter Plot
Source ANGPT Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2424 0.000000040253461644587726 Scatter Plot
Target ANGPT Target OSM OSM Secreted Signaling 0.2490 0.000000016703596228067448 Scatter Plot
Target ANGPT Target NODAL NODAL Secreted Signaling 0.2490 0.000000016604053178217136 Scatter Plot
Source ANGPT Target SELL SELL Cell-Cell Contact 0.2519 0.000000011196467350964204 Scatter Plot
Source ANGPT Source GP1BA GP1BA Cell-Cell Contact 0.2577 0.000000005002893170503701 Scatter Plot
Source ANGPT Source NT NT Secreted Signaling 0.2637 0.0000000021066044068121193 Scatter Plot
Source ANGPT Target VEGF VEGF Secreted Signaling 0.2638 0.0000000021005855494638715 Scatter Plot
Source ANGPT Source ANGPTL ANGPTL Secreted Signaling 0.2702 0.0000000008146868872508881 Scatter Plot
Source ANGPT Source IL2 IL2 Secreted Signaling 0.2755 0.00000000036687913919327176 Scatter Plot
Target ANGPT Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.2771 0.000000000286614307061128 Scatter Plot
Source ANGPT Target CSPG4 CSPG4 Cell-Cell Contact 0.2849 0.00000000008613744628837836 Scatter Plot
Source ANGPT Source CD39 CD39 Cell-Cell Contact 0.2967 0.000000000012763403668442835 Scatter Plot
Source ANGPT Target COMPLEMENT COMPLEMENT Secreted Signaling 0.3033 0.0000000000042398180160923695 Scatter Plot
Source ANGPT Source CD46 CD46 Cell-Cell Contact 0.3067 0.0000000000023783481299843133 Scatter Plot
Source ANGPT Target GDF GDF Secreted Signaling 0.3070 0.000000000002245633565067096 Scatter Plot
Source ANGPT Source CD1D2 CD1D2 Cell-Cell Contact 0.3172 0.000000000000378109731117409 Scatter Plot
Source ANGPT Source VEGF VEGF Secreted Signaling 0.3176 0.0000000000003508035726177512 Scatter Plot
Source ANGPT Target PTN PTN Secreted Signaling 0.3227 0.0000000000001403395852080852 Scatter Plot
Source ANGPT Source GDF GDF Secreted Signaling 0.3328 0.000000000000021456808538338483 Scatter Plot
Source ANGPT Source IL16 IL16 Secreted Signaling 0.3356 0.000000000000012597268474738284 Scatter Plot
Source ANGPT Source NOTCH NOTCH Cell-Cell Contact 0.3491 0.0000000000000008887353129223626 Scatter Plot
Source ANGPT Target NODAL NODAL Secreted Signaling 0.3518 0.0000000000000005158040067030093 Scatter Plot
Source ANGPT Target ANGPTL ANGPTL Secreted Signaling 0.3535 0.00000000000000036103879356460474 Scatter Plot
Source ANGPT Target SEMA6 SEMA6 Cell-Cell Contact 0.3551 0.00000000000000026075852394614547 Scatter Plot
Target ANGPT Target CD22 CD22 Cell-Cell Contact 0.3647 0.000000000000000035617022162864866 Scatter Plot
Target ANGPT Target BAFF BAFF Secreted Signaling 0.3672 0.00000000000000002092069794185243 Scatter Plot
Source ANGPT Source THY1 THY1 Cell-Cell Contact 0.3776 0.0000000000000000021712927384762408 Scatter Plot
Source ANGPT Source VCAM VCAM Cell-Cell Contact 0.3796 0.0000000000000000013678420443739308 Scatter Plot
Source ANGPT Target SPP1 SPP1 Secreted Signaling 0.3803 0.0000000000000000011908749127466631 Scatter Plot
Source ANGPT Target THBS THBS ECM-Receptor 0.3809 0.0000000000000000010265471151624552 Scatter Plot
Source ANGPT Source CCL CCL Secreted Signaling 0.3812 0.000000000000000000967527934939611 Scatter Plot
Target ANGPT Target APP APP Cell-Cell Contact 0.3826 0.0000000000000000007018176795309523 Scatter Plot
Source ANGPT Target MK MK Secreted Signaling 0.3867 0.00000000000000000027425927147589585 Scatter Plot
Source ANGPT Target SEMA5 SEMA5 Cell-Cell Contact 0.3951 0.00000000000000000003931665049383178 Scatter Plot
Source ANGPT Target FN1 FN1 ECM-Receptor 0.3998 0.000000000000000000012800226716872948 Scatter Plot
Target ANGPT Target SEMA4 SEMA4 Cell-Cell Contact 0.4101 0.0000000000000000000010542476148831129 Scatter Plot
Source ANGPT Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.4149 0.00000000000000000000031261119883743943 Scatter Plot
Source ANGPT Target VISFATIN VISFATIN Secreted Signaling 0.4197 0.00000000000000000000009408313599982573 Scatter Plot
Source ANGPT Source CXCL CXCL Secreted Signaling 0.4244 0.000000000000000000000027598365372603604 Scatter Plot
Source ANGPT Source PROS PROS Secreted Signaling 0.4356 0.0000000000000000000000014078906532631812 Scatter Plot
Source ANGPT Source CSF CSF Secreted Signaling 0.4361 0.0000000000000000000000012330382822073904 Scatter Plot
Source ANGPT Source IGF IGF Secreted Signaling 0.4385 0.00000000000000000000000065283409608908555 Scatter Plot
Target ANGPT Target NRG NRG Secreted Signaling 0.4444 0.00000000000000000000000012674273074518082 Scatter Plot
Source ANGPT Source CX3C CX3C Secreted Signaling 0.4503 0.000000000000000000000000023942986024099396 Scatter Plot
Source ANGPT Target SEMA7 SEMA7 Cell-Cell Contact 0.4580 0.000000000000000000000000002635571756615869 Scatter Plot
Source ANGPT Target ACTIVIN ACTIVIN Secreted Signaling 0.4595 0.0000000000000000000000000017144370440007654 Scatter Plot
Source ANGPT Source PSAP PSAP Secreted Signaling 0.4691 0.00000000000000000000000000009862248296620199 Scatter Plot
Source ANGPT Target NPR2 NPR2 Secreted Signaling 0.4749 0.000000000000000000000000000017085883329128158 Scatter Plot
Source ANGPT Source CD45 CD45 Cell-Cell Contact 0.4757 0.00000000000000000000000000001312763625312542 Scatter Plot
Source ANGPT Target CD22 CD22 Cell-Cell Contact 0.4757 0.00000000000000000000000000001312763625312542 Scatter Plot
Source ANGPT Source ICAM ICAM Cell-Cell Contact 0.4784 0.0000000000000000000000000000057046686509279945 Scatter Plot
Source ANGPT Target PERIOSTIN PERIOSTIN Secreted Signaling 0.4798 0.000000000000000000000000000003744693640015613 Scatter Plot
Source ANGPT Target BMP BMP Secreted Signaling 0.4902 0.00000000000000000000000000000013745703813433803 Scatter Plot
Source ANGPT Source CD86 CD86 Cell-Cell Contact 0.4936 0.00000000000000000000000000000004534665616460218 Scatter Plot
Source ANGPT Target NRG NRG Secreted Signaling 0.4988 0.000000000000000000000000000000008075013344071579 Scatter Plot
Source ANGPT Target BSP BSP ECM-Receptor 0.4988 0.000000000000000000000000000000008009446038612502 Scatter Plot
Source ANGPT Target DMP1 DMP1 ECM-Receptor 0.5040 0.0000000000000000000000000000000014052247456738193 Scatter Plot
Source ANGPT Source LCK LCK Cell-Cell Contact 0.5146 0.00000000000000000000000000000000003630378159859376 Scatter Plot
Source ANGPT Target LAMININ LAMININ ECM-Receptor 0.5158 0.00000000000000000000000000000000002377978350736825 Scatter Plot
Source ANGPT Target EPHB EPHB Cell-Cell Contact 0.5160 0.00000000000000000000000000000000002232281712578541 Scatter Plot
Source ANGPT Source MK MK Secreted Signaling 0.5195 0.000000000000000000000000000000000006523467269600745 Scatter Plot
Source ANGPT Source FLT3 FLT3 Secreted Signaling 0.5266 0.0000000000000000000000000000000000004995818438169359 Scatter Plot
Target ANGPT Target CD34 CD34 Cell-Cell Contact 0.5408 0.0000000000000000000000000000000000000024937255897664458 Scatter Plot
Source ANGPT Source CDH CDH Cell-Cell Contact 0.5426 0.0000000000000000000000000000000000000012328833808404689 Scatter Plot
Source ANGPT Target CDH CDH Cell-Cell Contact 0.5426 0.0000000000000000000000000000000000000012328833808404689 Scatter Plot
Source ANGPT Target TGFb TGFb Secreted Signaling 0.5449 0.00000000000000000000000000000000000000050580399863448645 Scatter Plot
Source ANGPT Source IL7 IL7 Secreted Signaling 0.5456 0.0000000000000000000000000000000000000003861796318220704 Scatter Plot
Source ANGPT Target VTN VTN ECM-Receptor 0.5457 0.0000000000000000000000000000000000000003681137222617546 Scatter Plot
Target ANGPT Target PARs PARs Secreted Signaling 0.5466 0.00000000000000000000000000000000000000026721295343951676 Scatter Plot
Source ANGPT Source PDGF PDGF Secreted Signaling 0.5473 0.0000000000000000000000000000000000000002012441722944662 Scatter Plot
Source ANGPT Source BST2 BST2 Cell-Cell Contact 0.5651 0.00000000000000000000000000000000000000000015291128142532485 Scatter Plot
Source ANGPT Target BAFF BAFF Secreted Signaling 0.5687 0.000000000000000000000000000000000000000000033532936293955253 Scatter Plot
Source ANGPT Source EPHB EPHB Cell-Cell Contact 0.5716 0.000000000000000000000000000000000000000000009832055521141569 Scatter Plot
Source ANGPT Target CD200 CD200 Cell-Cell Contact 0.5738 0.0000000000000000000000000000000000000000000039003923187718974 Scatter Plot
Source ANGPT Target SEMA4 SEMA4 Cell-Cell Contact 0.5836 0.00000000000000000000000000000000000000000000005494008425082977 Scatter Plot
Source ANGPT Target SLURP SLURP Secreted Signaling 0.5862 0.000000000000000000000000000000000000000000000016987807153468268 Scatter Plot
Source ANGPT Target APP APP Cell-Cell Contact 0.5862 0.000000000000000000000000000000000000000000000016896728714582663 Scatter Plot
Source ANGPT Target VWF VWF ECM-Receptor 0.6029 0.000000000000000000000000000000000000000000000000008047573753065467 Scatter Plot
Source ANGPT Target JAM JAM Cell-Cell Contact 0.6047 0.0000000000000000000000000000000000000000000000000033051797202493864 Scatter Plot
Source ANGPT Source SEMA7 SEMA7 Cell-Cell Contact 0.6067 0.0000000000000000000000000000000000000000000000000013170571628365074 Scatter Plot
Source ANGPT Target FGF FGF Secreted Signaling 0.6116 0.00000000000000000000000000000000000000000000000000012024106207039617 Scatter Plot
Source ANGPT Target IGF IGF Secreted Signaling 0.6246 0.00000000000000000000000000000000000000000000000000000018095499001983248 Scatter Plot
Source ANGPT Source BMP BMP Secreted Signaling 0.6288 0.000000000000000000000000000000000000000000000000000000020614819108015843 Scatter Plot
Source ANGPT Target KIT KIT Secreted Signaling 0.6544 0.00000000000000000000000000000000000000000000000000000000000001830995325731781 Scatter Plot
Source ANGPT Target TENASCIN TENASCIN ECM-Receptor 0.6599 0.0000000000000000000000000000000000000000000000000000000000000007566182775638666 Scatter Plot
Source ANGPT Target MIF MIF Secreted Signaling 0.6616 0.0000000000000000000000000000000000000000000000000000000000000002799875553861911 Scatter Plot
Source ANGPT Target CD34 CD34 Cell-Cell Contact 0.6709 0.00000000000000000000000000000000000000000000000000000000000000000106014874977371 Scatter Plot
Source ANGPT Target PARs PARs Secreted Signaling 0.6789 0.000000000000000000000000000000000000000000000000000000000000000000007630265258816227 Scatter Plot
Source ANGPT Source COLLAGEN COLLAGEN ECM-Receptor 0.6848 0.00000000000000000000000000000000000000000000000000000000000000000000017057483484741834 Scatter Plot
Source ANGPT Target ncWNT ncWNT Secreted Signaling 0.6853 0.00000000000000000000000000000000000000000000000000000000000000000000012904108095130457 Scatter Plot
Source ANGPT Source GAS GAS Secreted Signaling 0.6856 0.00000000000000000000000000000000000000000000000000000000000000000000010646570757355358 Scatter Plot
Source ANGPT Target ESAM ESAM Cell-Cell Contact 0.6951 0.00000000000000000000000000000000000000000000000000000000000000000000000019514860883088432 Scatter Plot
Source ANGPT Source ESAM ESAM Cell-Cell Contact 0.6951 0.00000000000000000000000000000000000000000000000000000000000000000000000019514860883088432 Scatter Plot
Source ANGPT Target CD39 CD39 Cell-Cell Contact 0.6979 0.000000000000000000000000000000000000000000000000000000000000000000000000029739507849364803 Scatter Plot
Source ANGPT Target WNT WNT Secreted Signaling 0.7105 0.000000000000000000000000000000000000000000000000000000000000000000000000000004400939570591478 Scatter Plot
Source ANGPT Source JAM JAM Cell-Cell Contact 0.7231 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000041589325623328746 Scatter Plot
Source ANGPT Source MHC-I MHC-I Cell-Cell Contact 0.7922 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576301133088149 Scatter Plot
Source ANGPT Source MHC-II MHC-II Cell-Cell Contact 0.8118 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633115328717955 Scatter Plot
Source ANGPT Source CD52 CD52 Cell-Cell Contact -0.5876 0.000000000000000000000000000000000000000000000009216175671503356 Scatter Plot
Source ANGPT Source COMPLEMENT COMPLEMENT Secreted Signaling -0.5764 0.0000000000000000000000000000000000000000000013014728873542697 Scatter Plot
Source ANGPT Source SELL SELL Cell-Cell Contact -0.5154 0.000000000000000000000000000000000027280093363454697 Scatter Plot
Source ANGPT Source SEMA4 SEMA4 Cell-Cell Contact -0.5086 0.0000000000000000000000000000000002886213944678698 Scatter Plot
Source ANGPT Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.5058 0.0000000000000000000000000000000007566454113344624 Scatter Plot
Source ANGPT Target CD52 CD52 Cell-Cell Contact -0.4706 0.00000000000000000000000000006327815788239215 Scatter Plot
Source ANGPT Source VISTA VISTA Cell-Cell Contact -0.4678 0.0000000000000000000000000001474047608003811 Scatter Plot
Source ANGPT Target ICAM ICAM Cell-Cell Contact -0.4667 0.0000000000000000000000000002020915950689146 Scatter Plot
Source ANGPT Target CSF CSF Secreted Signaling -0.4248 0.000000000000000000000025036631427725253 Scatter Plot
Source ANGPT Target IFN-II IFN-II Secreted Signaling -0.4171 0.00000000000000000000018017241282264261 Scatter Plot
Source ANGPT Target VCAM VCAM Cell-Cell Contact -0.3960 0.000000000000000000031997457620515024 Scatter Plot
Source ANGPT Target CCL CCL Secreted Signaling -0.3606 0.00000000000000008363235333965004 Scatter Plot
Source ANGPT Target CEACAM CEACAM Cell-Cell Contact -0.3587 0.0000000000000001237455853514267 Scatter Plot
Source ANGPT Target CXCL CXCL Secreted Signaling -0.3557 0.0000000000000002326551188486939 Scatter Plot
Target ANGPT Target ICAM ICAM Cell-Cell Contact -0.3507 0.0000000000000006455370497438225 Scatter Plot
Target ANGPT Target CD52 CD52 Cell-Cell Contact -0.3490 0.0000000000000009021085204850756 Scatter Plot
Source ANGPT Source CLEC CLEC Cell-Cell Contact -0.3408 0.0000000000000046018986436461304 Scatter Plot
Source ANGPT Source SPP1 SPP1 Secreted Signaling -0.3132 0.0000000000007715687465538885 Scatter Plot
Target ANGPT Target CCL CCL Secreted Signaling -0.3006 0.000000000006657094488637953 Scatter Plot
Source ANGPT Source MIF MIF Secreted Signaling -0.3005 0.000000000006818076369017728 Scatter Plot
Source ANGPT Target CLEC CLEC Cell-Cell Contact -0.2971 0.000000000011866921173631676 Scatter Plot
Source ANGPT Source APP APP Cell-Cell Contact -0.2920 0.000000000027364673449508562 Scatter Plot
Source ANGPT Source ANNEXIN ANNEXIN Secreted Signaling -0.2878 0.00000000005395139931252627 Scatter Plot
Source ANGPT Source NCAM NCAM Cell-Cell Contact -0.2845 0.00000000009098061118648963 Scatter Plot
Target ANGPT Target IFN-II IFN-II Secreted Signaling -0.2796 0.00000000019745139558046995 Scatter Plot
Target ANGPT Target CLEC CLEC Cell-Cell Contact -0.2661 0.0000000014990774045155851 Scatter Plot
Source ANGPT Target IL17 IL17 Secreted Signaling -0.2600 0.0000000036003407961866612 Scatter Plot
Source ANGPT Source CCL CCL Secreted Signaling -0.2584 0.000000004554641736156344 Scatter Plot
Source ANGPT Source TGFb TGFb Secreted Signaling -0.2578 0.000000004910420998524329 Scatter Plot
Source ANGPT Target VEGF VEGF Secreted Signaling -0.2318 0.0000001586568723012672 Scatter Plot
Source ANGPT Target SEMA3 SEMA3 Secreted Signaling -0.2291 0.0000002235119266455104 Scatter Plot
Source ANGPT Source TNF TNF Secreted Signaling -0.2081 0.000002695616270889968 Scatter Plot
Source ANGPT Target ANNEXIN ANNEXIN Secreted Signaling -0.2074 0.000002922385776240688 Scatter Plot
Source ANGPT Source ANGPTL ANGPTL Secreted Signaling -0.2051 0.000003782172837046919 Scatter Plot
Source ANGPT Target COLLAGEN COLLAGEN ECM-Receptor -0.1937 0.000012850414084203072 Scatter Plot
Source ANGPT Source VISFATIN VISFATIN Secreted Signaling -0.1769 0.00006984170709030559 Scatter Plot
Source ANGPT Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1720 0.0001110335746642 Scatter Plot
Source ANGPT Source GRN GRN Secreted Signaling -0.1649 0.0002120988837256 Scatter Plot
Source ANGPT Source NKG2D NKG2D Cell-Cell Contact -0.1530 0.0005951217933452 Scatter Plot
Source ANGPT Source BAFF BAFF Secreted Signaling -0.1442 0.0012243315810168 Scatter Plot
Target ANGPT Target ANNEXIN ANNEXIN Secreted Signaling -0.1343 0.0026165776565008 Scatter Plot
Source ANGPT Source LAIR1 LAIR1 Cell-Cell Contact -0.1325 0.0029823510584208 Scatter Plot
Source ANGPT Target GRN GRN Secreted Signaling -0.1300 0.0035928081651523 Scatter Plot
Target ANGPT Target GRN GRN Secreted Signaling -0.1256 0.0049274600232648 Scatter Plot

Cells that are targets of ANGPT from HSCs*

Cells that are source of ANGPT to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.