Pathway: TWEAK

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Secreted Signaling

Details on the TWEAK pathway:

Specificity Index HSPC as target: 0.123
HSPC as source: 0.410

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the TWEAK pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target TWEAK Target EPHA EPHA Cell-Cell Contact 0.0964 0.0311619019078578 Scatter Plot
Target TWEAK Source ICOS ICOS Cell-Cell Contact 0.0966 0.0308699816542722 Scatter Plot
Target TWEAK Source JAM JAM Cell-Cell Contact 0.0969 0.0303609137009723 Scatter Plot
Target TWEAK Source PTN PTN Secreted Signaling 0.0971 0.0299934578744389 Scatter Plot
Target TWEAK Source RANKL RANKL Secreted Signaling 0.1013 0.0235228542764414 Scatter Plot
Target TWEAK Source AGRN AGRN ECM-Receptor 0.1028 0.0215100265445641 Scatter Plot
Target TWEAK Source CSF CSF Secreted Signaling 0.1032 0.0209694505051451 Scatter Plot
Target TWEAK Target TGFb TGFb Secreted Signaling 0.1041 0.0199000164028045 Scatter Plot
Target TWEAK Target CD200 CD200 Cell-Cell Contact 0.1041 0.0198876884467524 Scatter Plot
Target TWEAK Target WNT WNT Secreted Signaling 0.1052 0.0186400527643247 Scatter Plot
Source TWEAK Source THBS THBS ECM-Receptor 0.1058 0.0179960965902501 Scatter Plot
Target TWEAK Source ICAM ICAM Cell-Cell Contact 0.1069 0.0167625287593061 Scatter Plot
Target TWEAK Target SEMA3 SEMA3 Secreted Signaling 0.1096 0.0141631858144294 Scatter Plot
Target TWEAK Source FGF FGF Secreted Signaling 0.1099 0.0139173746690607 Scatter Plot
Target TWEAK Target APP APP Cell-Cell Contact 0.1112 0.0128553177437736 Scatter Plot
Target TWEAK Source TGFb TGFb Secreted Signaling 0.1112 0.0128102354064775 Scatter Plot
Target TWEAK Source MHC-I MHC-I Cell-Cell Contact 0.1121 0.0121439396020433 Scatter Plot
Target TWEAK Source CCL CCL Secreted Signaling 0.1140 0.0107168588440675 Scatter Plot
Target TWEAK Source CXCL CXCL Secreted Signaling 0.1140 0.0107141004811307 Scatter Plot
Target TWEAK Target MIF MIF Secreted Signaling 0.1147 0.0102488485541512 Scatter Plot
Target TWEAK Source THY1 THY1 Cell-Cell Contact 0.1156 0.009679148823948 Scatter Plot
Target TWEAK Source SEMA4 SEMA4 Cell-Cell Contact 0.1161 0.0093855058042841 Scatter Plot
Target TWEAK Source BMP BMP Secreted Signaling 0.1216 0.0064695663919644 Scatter Plot
Target TWEAK Source PDGF PDGF Secreted Signaling 0.1230 0.0058847429344051 Scatter Plot
Target TWEAK Source GALECTIN GALECTIN Secreted Signaling 0.1347 0.0025355142605054 Scatter Plot
Target TWEAK Target MK MK Secreted Signaling 0.1388 0.0018708728446045 Scatter Plot
Target TWEAK Target EPHB EPHB Cell-Cell Contact 0.1435 0.0012955681088893 Scatter Plot
Target TWEAK Target GAS GAS Secreted Signaling 0.1436 0.0012810490661635 Scatter Plot
Target TWEAK Source COLLAGEN COLLAGEN ECM-Receptor 0.1491 0.0008219990415984 Scatter Plot
Source TWEAK Source PTN PTN Secreted Signaling 0.1579 0.0003922432700331 Scatter Plot
Target TWEAK Source MHC-II MHC-II Cell-Cell Contact 0.1608 0.0003069547298256 Scatter Plot
Target TWEAK Source SELPLG SELPLG Cell-Cell Contact 0.1643 0.0002248833342531 Scatter Plot
Target TWEAK Source ANGPT ANGPT Secreted Signaling 0.1697 0.0001370293150236 Scatter Plot
Target TWEAK Target KIT KIT Secreted Signaling 0.1786 0.00005916954204107503 Scatter Plot
Target TWEAK Source BST2 BST2 Cell-Cell Contact 0.1963 0.00000977955833315693 Scatter Plot
Target TWEAK Source MIF MIF Secreted Signaling 0.2139 0.0000013814172199591904 Scatter Plot
Target TWEAK Source ANGPTL ANGPTL Secreted Signaling 0.2174 0.000000923014177716687 Scatter Plot
Target TWEAK Source CD34 CD34 Cell-Cell Contact 0.2237 0.0000004340970768720066 Scatter Plot
Source TWEAK Source VEGF VEGF Secreted Signaling 0.2657 0.000000001587244770671456 Scatter Plot
Source TWEAK Source JAM JAM Cell-Cell Contact 0.7019 0.0000000000000000000000000000000000000000000000000000000000000000000000000018941292314055022 Scatter Plot
Target TWEAK Source NCAM NCAM Cell-Cell Contact -0.2445 0.00000003061989380603771 Scatter Plot
Source TWEAK Source TNF TNF Secreted Signaling -0.2205 0.0000006401870120488975 Scatter Plot
Target TWEAK Source GRN GRN Secreted Signaling -0.1586 0.0003707678664164 Scatter Plot
Target TWEAK Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1539 0.0005541538036873 Scatter Plot
Target TWEAK Source ANNEXIN ANNEXIN Secreted Signaling -0.1538 0.0005562638298241 Scatter Plot
Target TWEAK Target NCAM NCAM Cell-Cell Contact -0.1500 0.000767977240767 Scatter Plot
Target TWEAK Source COMPLEMENT COMPLEMENT Secreted Signaling -0.1479 0.000912849099404 Scatter Plot
Target TWEAK Source VISTA VISTA Cell-Cell Contact -0.1407 0.0016110291614926 Scatter Plot
Target TWEAK Source BAFF BAFF Secreted Signaling -0.1328 0.0029368475528747 Scatter Plot
Target TWEAK Target THY1 THY1 Cell-Cell Contact -0.1316 0.0032014981991713 Scatter Plot
Target TWEAK Target ICAM ICAM Cell-Cell Contact -0.1171 0.0087502667983411 Scatter Plot
Target TWEAK Source SEMA4 SEMA4 Cell-Cell Contact -0.1078 0.0158480231434494 Scatter Plot
Target TWEAK Target ANGPTL ANGPTL Secreted Signaling -0.1014 0.0234230899381934 Scatter Plot
Target TWEAK Target VISFATIN VISFATIN Secreted Signaling 0.0972 0.0298364624131141 Scatter Plot
Target TWEAK Target IL6 IL6 Secreted Signaling 0.1008 0.0242579364982152 Scatter Plot
Source TWEAK Source THBS THBS ECM-Receptor 0.1057 0.0180289037441795 Scatter Plot
Target TWEAK Target TGFb TGFb Secreted Signaling 0.1063 0.0174663679163504 Scatter Plot
Target TWEAK Target CD34 CD34 Cell-Cell Contact 0.1163 0.0092287827658344 Scatter Plot
Target TWEAK Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1167 0.0090110861465126 Scatter Plot
Source TWEAK Target GALECTIN GALECTIN Secreted Signaling 0.1354 0.0024144498366417 Scatter Plot
Source TWEAK Source SEMA6 SEMA6 Cell-Cell Contact 0.1366 0.0021981209821199 Scatter Plot
Source TWEAK Target GAS GAS Secreted Signaling 0.1405 0.0016371035109431 Scatter Plot
Target TWEAK Target SEMA4 SEMA4 Cell-Cell Contact 0.1463 0.0010313640661749 Scatter Plot
Source TWEAK Target VEGF VEGF Secreted Signaling 0.1695 0.0001399931461558 Scatter Plot
Source TWEAK Source GP1BA GP1BA Cell-Cell Contact 0.1745 0.00008764300951077067 Scatter Plot
Target TWEAK Target PDGF PDGF Secreted Signaling 0.1791 0.00005651348286327565 Scatter Plot
Source TWEAK Source APELIN APELIN Secreted Signaling 0.1797 0.00005308268123172123 Scatter Plot
Source TWEAK Target NOTCH NOTCH Cell-Cell Contact 0.1814 0.00004524741066414396 Scatter Plot
Source TWEAK Target THY1 THY1 Cell-Cell Contact 0.2000 0.000006620671915060796 Scatter Plot
Source TWEAK Source CD1D2 CD1D2 Cell-Cell Contact 0.2015 0.000005600283267227505 Scatter Plot
Target TWEAK Target PTN PTN Secreted Signaling 0.2137 0.0000014250396028987303 Scatter Plot
Source TWEAK Source ANGPTL ANGPTL Secreted Signaling 0.2162 0.000001055537018922485 Scatter Plot
Source TWEAK Target NODAL NODAL Secreted Signaling 0.2207 0.0000006226892766953999 Scatter Plot
Source TWEAK Source WNT WNT Secreted Signaling 0.2249 0.000000372923937459905 Scatter Plot
Source TWEAK Target RANKL RANKL Secreted Signaling 0.2258 0.0000003348062170757949 Scatter Plot
Target TWEAK Target SELL SELL Cell-Cell Contact 0.2276 0.0000002691167383861538 Scatter Plot
Source TWEAK Source GDF GDF Secreted Signaling 0.2325 0.0000001450199281095148 Scatter Plot
Source TWEAK Source SEMA3 SEMA3 Secreted Signaling 0.2334 0.0000001302764643509877 Scatter Plot
Source TWEAK Target CD23 CD23 Cell-Cell Contact 0.2343 0.00000011535860244445917 Scatter Plot
Source TWEAK Target GDF GDF Secreted Signaling 0.2351 0.00000010516008687697244 Scatter Plot
Source TWEAK Target IL6 IL6 Secreted Signaling 0.2381 0.00000007105229020495504 Scatter Plot
Source TWEAK Target PTN PTN Secreted Signaling 0.2415 0.000000045615600734159866 Scatter Plot
Source TWEAK Target SEMA3 SEMA3 Secreted Signaling 0.2443 0.00000003141459696865808 Scatter Plot
Source TWEAK Target EPHA EPHA Cell-Cell Contact 0.2451 0.00000002834795459460905 Scatter Plot
Source TWEAK Target NCAM NCAM Cell-Cell Contact 0.2498 0.000000014954743920881437 Scatter Plot
Source TWEAK Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2502 0.000000014088202538059836 Scatter Plot
Source TWEAK Source ncWNT ncWNT Secreted Signaling 0.2518 0.000000011340209401731474 Scatter Plot
Source TWEAK Target COLLAGEN COLLAGEN ECM-Receptor 0.2534 0.000000009067971967790588 Scatter Plot
Source TWEAK Target AGT AGT Secreted Signaling 0.2582 0.000000004643633954406742 Scatter Plot
Source TWEAK Source THY1 THY1 Cell-Cell Contact 0.2890 0.000000000044558689328269856 Scatter Plot
Source TWEAK Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2987 0.000000000009132174286943792 Scatter Plot
Source TWEAK Source VCAM VCAM Cell-Cell Contact 0.3018 0.000000000005466838099704386 Scatter Plot
Source TWEAK Source CXCL CXCL Secreted Signaling 0.3038 0.000000000003901300402263561 Scatter Plot
Source TWEAK Target MK MK Secreted Signaling 0.3078 0.0000000000019669015980020395 Scatter Plot
Source TWEAK Source CD46 CD46 Cell-Cell Contact 0.3106 0.0000000000011962047502430366 Scatter Plot
Source TWEAK Target OSM OSM Secreted Signaling 0.3173 0.00000000000037232986831732246 Scatter Plot
Source TWEAK Source IL16 IL16 Secreted Signaling 0.3189 0.0000000000002789207366807509 Scatter Plot
Source TWEAK Source CCL CCL Secreted Signaling 0.3240 0.00000000000010915064385361061 Scatter Plot
Source TWEAK Source CD39 CD39 Cell-Cell Contact 0.3257 0.00000000000008060021527751946 Scatter Plot
Source TWEAK Target SEMA6 SEMA6 Cell-Cell Contact 0.3275 0.0000000000000574725067146508 Scatter Plot
Source TWEAK Target FN1 FN1 ECM-Receptor 0.3344 0.00000000000001563506319526209 Scatter Plot
Source TWEAK Target CSPG4 CSPG4 Cell-Cell Contact 0.3373 0.000000000000009104732561154476 Scatter Plot
Source TWEAK Target CADM CADM Cell-Cell Contact 0.3451 0.000000000000001985228696688703 Scatter Plot
Source TWEAK Source CADM CADM Cell-Cell Contact 0.3451 0.000000000000001985228696688703 Scatter Plot
Source TWEAK Target ANGPTL ANGPTL Secreted Signaling 0.3513 0.0000000000000005651710339927537 Scatter Plot
Source TWEAK Target SPP1 SPP1 Secreted Signaling 0.3545 0.0000000000000002992921979233393 Scatter Plot
Source TWEAK Source LCK LCK Cell-Cell Contact 0.3633 0.00000000000000004757774798562597 Scatter Plot
Source TWEAK Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.3633 0.000000000000000047493372502513267 Scatter Plot
Source TWEAK Source LIGHT LIGHT Secreted Signaling 0.3655 0.000000000000000029955055958825776 Scatter Plot
Source TWEAK Target ACTIVIN ACTIVIN Secreted Signaling 0.3698 0.000000000000000012011517536895132 Scatter Plot
Source TWEAK Source LAMININ LAMININ ECM-Receptor 0.3842 0.000000000000000000487762727887622 Scatter Plot
Source TWEAK Source IL2 IL2 Secreted Signaling 0.3858 0.00000000000000000033816897273792413 Scatter Plot
Source TWEAK Source CD86 CD86 Cell-Cell Contact 0.3908 0.00000000000000000010633555734410845 Scatter Plot
Source TWEAK Target THBS THBS ECM-Receptor 0.3959 0.000000000000000000032209391157061896 Scatter Plot
Source TWEAK Target SEMA5 SEMA5 Cell-Cell Contact 0.3974 0.000000000000000000023080251806353735 Scatter Plot
Source TWEAK Source CX3C CX3C Secreted Signaling 0.4012 0.0000000000000000000091739596727461 Scatter Plot
Source TWEAK Target EPHB EPHB Cell-Cell Contact 0.4016 0.00000000000000000000844383264437901 Scatter Plot
Source TWEAK Source NOTCH NOTCH Cell-Cell Contact 0.4049 0.00000000000000000000377488730605242 Scatter Plot
Source TWEAK Source ICAM ICAM Cell-Cell Contact 0.4052 0.000000000000000000003509441854017199 Scatter Plot
Source TWEAK Source NT NT Secreted Signaling 0.4122 0.0000000000000000000006229754168853827 Scatter Plot
Source TWEAK Target TGFb TGFb Secreted Signaling 0.4170 0.00000000000000000000018302144682253704 Scatter Plot
Source TWEAK Target NPR2 NPR2 Secreted Signaling 0.4268 0.00000000000000000000001458984776495006 Scatter Plot
Source TWEAK Source IGF IGF Secreted Signaling 0.4299 0.000000000000000000000006489008429711337 Scatter Plot
Source TWEAK Target LAMININ LAMININ ECM-Receptor 0.4313 0.000000000000000000000004513208071540843 Scatter Plot
Source TWEAK Source RANKL RANKL Secreted Signaling 0.4351 0.0000000000000000000000016300583524801084 Scatter Plot
Source TWEAK Source EPHB EPHB Cell-Cell Contact 0.4353 0.0000000000000000000000015595897150446602 Scatter Plot
Source TWEAK Target BAFF BAFF Secreted Signaling 0.4380 0.0000000000000000000000007425275152739924 Scatter Plot
Source TWEAK Target CD22 CD22 Cell-Cell Contact 0.4420 0.00000000000000000000000024934386526039787 Scatter Plot
Source TWEAK Source CD45 CD45 Cell-Cell Contact 0.4420 0.00000000000000000000000024934386526039787 Scatter Plot
Source TWEAK Source PROS PROS Secreted Signaling 0.4430 0.0000000000000000000000001884711661257888 Scatter Plot
Source TWEAK Target SEMA7 SEMA7 Cell-Cell Contact 0.4530 0.000000000000000000000000011273355850732178 Scatter Plot
Source TWEAK Target BMP BMP Secreted Signaling 0.4549 0.000000000000000000000000006477699886865425 Scatter Plot
Source TWEAK Source CSF CSF Secreted Signaling 0.4567 0.000000000000000000000000003896615281998689 Scatter Plot
Source TWEAK Target VISFATIN VISFATIN Secreted Signaling 0.4608 0.000000000000000000000000001179889876024908 Scatter Plot
Source TWEAK Target KIT KIT Secreted Signaling 0.4645 0.0000000000000000000000000003926814694578423 Scatter Plot
Source TWEAK Source PSAP PSAP Secreted Signaling 0.4760 0.000000000000000000000000000012005709354569409 Scatter Plot
Source TWEAK Target SEMA4 SEMA4 Cell-Cell Contact 0.4809 0.0000000000000000000000000000026553466920976613 Scatter Plot
Source TWEAK Source MK MK Secreted Signaling 0.4886 0.00000000000000000000000000000022828006567332077 Scatter Plot
Source TWEAK Source FLT3 FLT3 Secreted Signaling 0.4896 0.00000000000000000000000000000016456441928510986 Scatter Plot
Source TWEAK Target CDH CDH Cell-Cell Contact 0.4912 0.0000000000000000000000000000000982954918459965 Scatter Plot
Source TWEAK Source CDH CDH Cell-Cell Contact 0.4912 0.0000000000000000000000000000000982954918459965 Scatter Plot
Source TWEAK Target CD200 CD200 Cell-Cell Contact 0.4942 0.00000000000000000000000000000003674541874457149 Scatter Plot
Source TWEAK Source LIFR LIFR Secreted Signaling 0.4970 0.000000000000000000000000000000014720165004233918 Scatter Plot
Source TWEAK Target ANGPT ANGPT Secreted Signaling 0.5010 0.000000000000000000000000000000003857753409054747 Scatter Plot
Source TWEAK Target PERIOSTIN PERIOSTIN Secreted Signaling 0.5022 0.0000000000000000000000000000000025994745890308338 Scatter Plot
Source TWEAK Target VTN VTN ECM-Receptor 0.5083 0.0000000000000000000000000000000003266410988564904 Scatter Plot
Source TWEAK Target VWF VWF ECM-Receptor 0.5118 0.00000000000000000000000000000000009829436177443167 Scatter Plot
Source TWEAK Source PDGF PDGF Secreted Signaling 0.5148 0.00000000000000000000000000000000003390447610278766 Scatter Plot
Source TWEAK Target BSP BSP ECM-Receptor 0.5255 0.0000000000000000000000000000000000007349855066872319 Scatter Plot
Source TWEAK Target NRG NRG Secreted Signaling 0.5288 0.00000000000000000000000000000000000021969554448503303 Scatter Plot
Source TWEAK Target DMP1 DMP1 ECM-Receptor 0.5308 0.00000000000000000000000000000000000010600255594581092 Scatter Plot
Source TWEAK Source COLLAGEN COLLAGEN ECM-Receptor 0.5314 0.00000000000000000000000000000000000008571168899504147 Scatter Plot
Source TWEAK Target APP APP Cell-Cell Contact 0.5426 0.000000000000000000000000000000000000001247376806306884 Scatter Plot
Source TWEAK Source IL7 IL7 Secreted Signaling 0.5455 0.00000000000000000000000000000000000000039783911658844675 Scatter Plot
Source TWEAK Target PARs PARs Secreted Signaling 0.5457 0.0000000000000000000000000000000000000003753502322760833 Scatter Plot
Source TWEAK Target SLURP SLURP Secreted Signaling 0.5474 0.00000000000000000000000000000000000000019148212428920724 Scatter Plot
Source TWEAK Source SEMA7 SEMA7 Cell-Cell Contact 0.5546 0.000000000000000000000000000000000000000011115287695627947 Scatter Plot
Source TWEAK Source BST2 BST2 Cell-Cell Contact 0.5552 0.000000000000000000000000000000000000000008637071961733835 Scatter Plot
Source TWEAK Target FGF FGF Secreted Signaling 0.5656 0.00000000000000000000000000000000000000000012314695019015266 Scatter Plot
Source TWEAK Target TENASCIN TENASCIN ECM-Receptor 0.5718 0.000000000000000000000000000000000000000000009272416808318833 Scatter Plot
Source TWEAK Target IGF IGF Secreted Signaling 0.5758 0.000000000000000000000000000000000000000000001640471822254363 Scatter Plot
Source TWEAK Target MIF MIF Secreted Signaling 0.5789 0.00000000000000000000000000000000000000000000043972664801963085 Scatter Plot
Source TWEAK Target ncWNT ncWNT Secreted Signaling 0.5919 0.0000000000000000000000000000000000000000000000013235001758801 Scatter Plot
Source TWEAK Source BMP BMP Secreted Signaling 0.5990 0.0000000000000000000000000000000000000000000000000504096136421439 Scatter Plot
Source TWEAK Target WNT WNT Secreted Signaling 0.6023 0.000000000000000000000000000000000000000000000000010377574221933101 Scatter Plot
Source TWEAK Target CD34 CD34 Cell-Cell Contact 0.6024 0.000000000000000000000000000000000000000000000000010146061550017648 Scatter Plot
Source TWEAK Target CD39 CD39 Cell-Cell Contact 0.6166 0.000000000000000000000000000000000000000000000000000010399900733324471 Scatter Plot
Source TWEAK Source ANGPT ANGPT Secreted Signaling 0.6300 0.000000000000000000000000000000000000000000000000000000011151190315175168 Scatter Plot
Source TWEAK Source GAS GAS Secreted Signaling 0.6367 0.00000000000000000000000000000000000000000000000000000000031821640415323998 Scatter Plot
Source TWEAK Target JAM JAM Cell-Cell Contact 0.6489 0.00000000000000000000000000000000000000000000000000000000000039759052462224636 Scatter Plot
Source TWEAK Target ESAM ESAM Cell-Cell Contact 0.6586 0.0000000000000000000000000000000000000000000000000000000000000016045319042408866 Scatter Plot
Source TWEAK Source ESAM ESAM Cell-Cell Contact 0.6586 0.0000000000000000000000000000000000000000000000000000000000000016045319042408866 Scatter Plot
Source TWEAK Source MHC-II MHC-II Cell-Cell Contact 0.6643 0.00000000000000000000000000000000000000000000000000000000000000005620302427073266 Scatter Plot
Source TWEAK Source MHC-I MHC-I Cell-Cell Contact 0.6979 0.00000000000000000000000000000000000000000000000000000000000000000000000002994727889065674 Scatter Plot
Source TWEAK Source CD52 CD52 Cell-Cell Contact -0.5181 0.000000000000000000000000000000000010763745353589129 Scatter Plot
Source TWEAK Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.4261 0.000000000000000000000017905516207494065 Scatter Plot
Source TWEAK Target ICAM ICAM Cell-Cell Contact -0.4094 0.0000000000000000000012541175439999121 Scatter Plot
Source TWEAK Source COMPLEMENT COMPLEMENT Secreted Signaling -0.4060 0.000000000000000000002864810924013865 Scatter Plot
Source TWEAK Source SELL SELL Cell-Cell Contact -0.4036 0.000000000000000000005120692996589559 Scatter Plot
Source TWEAK Source PARs PARs Secreted Signaling -0.3766 0.000000000000000002672197794329452 Scatter Plot
Source TWEAK Target CD52 CD52 Cell-Cell Contact -0.3698 0.000000000000000011839340518354021 Scatter Plot
Source TWEAK Source MIF MIF Secreted Signaling -0.3518 0.0000000000000005151272841299928 Scatter Plot
Source TWEAK Target VCAM VCAM Cell-Cell Contact -0.3250 0.00000000000009213595200841873 Scatter Plot
Source TWEAK Source TGFb TGFb Secreted Signaling -0.3108 0.0000000000011630414179441365 Scatter Plot
Source TWEAK Target IFN-II IFN-II Secreted Signaling -0.2795 0.00000000019933230536258912 Scatter Plot
Source TWEAK Target CSF CSF Secreted Signaling -0.2741 0.0000000004537234307499397 Scatter Plot
Source TWEAK Target CXCL CXCL Secreted Signaling -0.2642 0.000000001964313843498991 Scatter Plot
Source TWEAK Source VISTA VISTA Cell-Cell Contact -0.2508 0.000000013027776573958292 Scatter Plot
Source TWEAK Target CCL CCL Secreted Signaling -0.2501 0.000000014447255369667569 Scatter Plot
Source TWEAK Source NCAM NCAM Cell-Cell Contact -0.2495 0.000000015579714485949422 Scatter Plot
Source TWEAK Source ANGPTL ANGPTL Secreted Signaling -0.2410 0.0000000487270995675941 Scatter Plot
Source TWEAK Target CEACAM CEACAM Cell-Cell Contact -0.2328 0.00000014028979064188694 Scatter Plot
Source TWEAK Target IL17 IL17 Secreted Signaling -0.2280 0.0000002545951930276869 Scatter Plot
Source TWEAK Target CLEC CLEC Cell-Cell Contact -0.2257 0.00000034103558193821737 Scatter Plot
Source TWEAK Source CCL CCL Secreted Signaling -0.2243 0.00000040411311942867 Scatter Plot
Source TWEAK Source TNF TNF Secreted Signaling -0.2205 0.0000006401870120488975 Scatter Plot
Source TWEAK Source CLEC CLEC Cell-Cell Contact -0.2193 0.0000007342018798328253 Scatter Plot
Source TWEAK Source NKG2D NKG2D Cell-Cell Contact -0.2145 0.0000012939226825799782 Scatter Plot
Source TWEAK Source SPP1 SPP1 Secreted Signaling -0.1937 0.000012955100040653794 Scatter Plot
Source TWEAK Source SEMA4 SEMA4 Cell-Cell Contact -0.1936 0.000013026905601954378 Scatter Plot
Source TWEAK Source ANNEXIN ANNEXIN Secreted Signaling -0.1812 0.00004610209806518782 Scatter Plot
Source TWEAK Target COLLAGEN COLLAGEN ECM-Receptor -0.1779 0.0000633567945347062 Scatter Plot
Target TWEAK Target CD23 CD23 Cell-Cell Contact -0.1625 0.0002634122085458 Scatter Plot
Source TWEAK Target VEGF VEGF Secreted Signaling -0.1581 0.0003886974864677 Scatter Plot
Target TWEAK Target VCAM VCAM Cell-Cell Contact -0.1544 0.0005309604968341 Scatter Plot
Target TWEAK Target CEACAM CEACAM Cell-Cell Contact -0.1524 0.0006266495584979 Scatter Plot
Target TWEAK Target IL1 IL1 Secreted Signaling -0.1441 0.0012336121259491 Scatter Plot
Target TWEAK Target GRN GRN Secreted Signaling -0.1352 0.0024517198596838 Scatter Plot
Target TWEAK Target THY1 THY1 Cell-Cell Contact -0.1316 0.0031882349497641 Scatter Plot
Source TWEAK Source SELPLG SELPLG Cell-Cell Contact -0.1300 0.003598078124973 Scatter Plot
Target TWEAK Target ANNEXIN ANNEXIN Secreted Signaling -0.1251 0.0050731012944919 Scatter Plot
Source TWEAK Target GRN GRN Secreted Signaling -0.1248 0.0051812856889249 Scatter Plot
Source TWEAK Target ANNEXIN ANNEXIN Secreted Signaling -0.1235 0.0057063814572527 Scatter Plot
Source TWEAK Source LAIR1 LAIR1 Cell-Cell Contact -0.1227 0.0060138127786441 Scatter Plot
Source TWEAK Source APP APP Cell-Cell Contact -0.1211 0.0067037431827263 Scatter Plot
Source TWEAK Source VISFATIN VISFATIN Secreted Signaling -0.1162 0.0093047283543358 Scatter Plot
Target TWEAK Target COLLAGEN COLLAGEN ECM-Receptor -0.1063 0.0174113504524637 Scatter Plot
Source TWEAK Target COMPLEMENT COMPLEMENT Secreted Signaling -0.1048 0.0190215836157881 Scatter Plot
Target TWEAK Target JAM JAM Cell-Cell Contact -0.1041 0.0198603583552682 Scatter Plot

Cells that are targets of TWEAK from HSCs*

Cells that are source of TWEAK to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.