Pathway: MK

colormap

Average Signaling Potential

  • Edge Color:
  • — HSCs as target
  • — HSCs as source

Pathway Category: Secreted Signaling

Details on the MK pathway:

Specificity Index HSPC as target: 0.981
HSPC as source: 0.383

Graph Terms:

  • Average Signaling Potential: Score given to cell-type pathway pair that describes the intensity of the potential interaction. This score is based on ligand/receptor gene expression levels.
  • HSC Percent: Proportion of HSCs that interact with the given cell type in the MK pathway.
  • Node Size: Node size refelcts percent of HSCs interacting
  • Node Color: Node color reflects Average Signaling Potential

Correlation Name Pathway Name Pathway Category Correlation Score -log10(adj. p-value) Plot
Target MK Source ncWNT ncWNT Secreted Signaling 0.1025 0.0218975525807144 Scatter Plot
Target MK Source IL1 IL1 Secreted Signaling 0.1078 0.0158652860717227 Scatter Plot
Target MK Target EPHA EPHA Cell-Cell Contact 0.1087 0.0150291098520986 Scatter Plot
Target MK Source NOTCH NOTCH Cell-Cell Contact 0.1088 0.0149368663070491 Scatter Plot
Source MK Source IL6 IL6 Secreted Signaling 0.1103 0.0136380406662475 Scatter Plot
Target MK Target GAS GAS Secreted Signaling 0.1126 0.0117330928959825 Scatter Plot
Target MK Source CADM CADM Cell-Cell Contact 0.1134 0.0111337986274767 Scatter Plot
Target MK Source SEMA3 SEMA3 Secreted Signaling 0.1195 0.0074601434584153 Scatter Plot
Target MK Source APELIN APELIN Secreted Signaling 0.1229 0.0059123127081127 Scatter Plot
Target MK Target GDF GDF Secreted Signaling 0.1241 0.0054575364041764 Scatter Plot
Target MK Source CD1D2 CD1D2 Cell-Cell Contact 0.1283 0.0040500515224087 Scatter Plot
Source MK Source CADM CADM Cell-Cell Contact 0.1312 0.0032824664805992 Scatter Plot
Target MK Source OSM OSM Secreted Signaling 0.1401 0.001680801735633 Scatter Plot
Source MK Source ncWNT ncWNT Secreted Signaling 0.1405 0.001636364702655 Scatter Plot
Target MK Source CCL CCL Secreted Signaling 0.1409 0.0015822450600242 Scatter Plot
Target MK Source IGF IGF Secreted Signaling 0.1420 0.0014599978984439 Scatter Plot
Target MK Source RANKL RANKL Secreted Signaling 0.1440 0.0012457198092627 Scatter Plot
Target MK Source CD46 CD46 Cell-Cell Contact 0.1453 0.0011255680111365 Scatter Plot
Target MK Source PTN PTN Secreted Signaling 0.1458 0.0010750581057171 Scatter Plot
Target MK Source TGFb TGFb Secreted Signaling 0.1478 0.0009174252224032 Scatter Plot
Target MK Source LAMININ LAMININ ECM-Receptor 0.1485 0.0008627658633911 Scatter Plot
Target MK Source MIF MIF Secreted Signaling 0.1604 0.000317623097432 Scatter Plot
Target MK Source SEMA4 SEMA4 Cell-Cell Contact 0.1706 0.0001262529094035 Scatter Plot
Target MK Source ANGPTL ANGPTL Secreted Signaling 0.1708 0.0001236857889854 Scatter Plot
Target MK Source IL2 IL2 Secreted Signaling 0.1726 0.0001047512096269 Scatter Plot
Target MK Target VEGF VEGF Secreted Signaling 0.1751 0.00008311051153426679 Scatter Plot
Source MK Source VCAM VCAM Cell-Cell Contact 0.1755 0.00007937925518844935 Scatter Plot
Target MK Source CD86 CD86 Cell-Cell Contact 0.1765 0.00007245022508677551 Scatter Plot
Source MK Source SEMA3 SEMA3 Secreted Signaling 0.1778 0.0000640194763722443 Scatter Plot
Target MK Target MIF MIF Secreted Signaling 0.1794 0.00005475325711433871 Scatter Plot
Target MK Target BMP BMP Secreted Signaling 0.1815 0.00004477066657497225 Scatter Plot
Target MK Source NT NT Secreted Signaling 0.1839 0.00003499026752270803 Scatter Plot
Target MK Source AGRN AGRN ECM-Receptor 0.1865 0.00002704157709969156 Scatter Plot
Source MK Source WNT WNT Secreted Signaling 0.1873 0.00002496527435660569 Scatter Plot
Target MK Source GDF GDF Secreted Signaling 0.1908 0.000017489774310955307 Scatter Plot
Target MK Source PROS PROS Secreted Signaling 0.1959 0.000010252581944629522 Scatter Plot
Target MK Source VEGF VEGF Secreted Signaling 0.2057 0.0000035120685688002027 Scatter Plot
Target MK Source THY1 THY1 Cell-Cell Contact 0.2062 0.0000033326491876490075 Scatter Plot
Target MK Source CX3C CX3C Secreted Signaling 0.2149 0.000001234850609860991 Scatter Plot
Target MK Source IL7 IL7 Secreted Signaling 0.2298 0.00000020298573462871762 Scatter Plot
Target MK Source PDGF PDGF Secreted Signaling 0.2319 0.00000015779635404566061 Scatter Plot
Source MK Source CD46 CD46 Cell-Cell Contact 0.2355 0.0000000992009769506214 Scatter Plot
Target MK Target ACTIVIN ACTIVIN Secreted Signaling 0.2396 0.00000005820311456532261 Scatter Plot
Target MK Source ICAM ICAM Cell-Cell Contact 0.2406 0.00000005100560725662384 Scatter Plot
Target MK Source CDH CDH Cell-Cell Contact 0.2414 0.00000004609818837467959 Scatter Plot
Target MK Source GAS GAS Secreted Signaling 0.2428 0.00000003830604411076199 Scatter Plot
Source MK Source LIGHT LIGHT Secreted Signaling 0.2476 0.000000020179278178925123 Scatter Plot
Target MK Source SEMA7 SEMA7 Cell-Cell Contact 0.2505 0.000000013697031136142817 Scatter Plot
Target MK Target TGFb TGFb Secreted Signaling 0.2559 0.000000006471915784665952 Scatter Plot
Target MK Target SLURP SLURP Secreted Signaling 0.2615 0.00000000291032014740878 Scatter Plot
Source MK Source GDF GDF Secreted Signaling 0.2668 0.0000000013556648002834722 Scatter Plot
Target MK Source FGF FGF Secreted Signaling 0.2733 0.0000000005105966906472573 Scatter Plot
Source MK Source CXCL CXCL Secreted Signaling 0.2735 0.0000000004998076264468809 Scatter Plot
Target MK Target EPHB EPHB Cell-Cell Contact 0.2741 0.0000000004576121435638044 Scatter Plot
Source MK Source CD39 CD39 Cell-Cell Contact 0.2822 0.00000000013083503855134424 Scatter Plot
Target MK Source COLLAGEN COLLAGEN ECM-Receptor 0.2905 0.000000000035073529265973066 Scatter Plot
Source MK Source NT NT Secreted Signaling 0.2926 0.00000000002520507387432697 Scatter Plot
Target MK Source BMP BMP Secreted Signaling 0.2929 0.000000000023893012119013 Scatter Plot
Target MK Source FLT3 FLT3 Secreted Signaling 0.2937 0.000000000020821574811294583 Scatter Plot
Source MK Source RANKL RANKL Secreted Signaling 0.2954 0.000000000015757728421682106 Scatter Plot
Target MK Source GP1BA GP1BA Cell-Cell Contact 0.2967 0.000000000012843291718051569 Scatter Plot
Target MK Source LCK LCK Cell-Cell Contact 0.3002 0.000000000007111565168405464 Scatter Plot
Target MK Target CD39 CD39 Cell-Cell Contact 0.3010 0.000000000006230042777548085 Scatter Plot
Target MK Source CXCL CXCL Secreted Signaling 0.3010 0.000000000006225873320731965 Scatter Plot
Target MK Source TWEAK TWEAK Secreted Signaling 0.3078 0.0000000000019669015980020395 Scatter Plot
Target MK Source JAM JAM Cell-Cell Contact 0.3211 0.0000000000001872539230226589 Scatter Plot
Target MK Source ESAM ESAM Cell-Cell Contact 0.3214 0.00000000000017657753818759268 Scatter Plot
Source MK Source LAMININ LAMININ ECM-Receptor 0.3251 0.00000000000008898289466376351 Scatter Plot
Source MK Source VEGF VEGF Secreted Signaling 0.3311 0.00000000000002948558227530534 Scatter Plot
Source MK Source LIFR LIFR Secreted Signaling 0.3336 0.00000000000001841670259994751 Scatter Plot
Target MK Source EPHB EPHB Cell-Cell Contact 0.3365 0.000000000000010462837607778448 Scatter Plot
Target MK Source MHC-II MHC-II Cell-Cell Contact 0.3432 0.000000000000002879644713047785 Scatter Plot
Target MK Source BST2 BST2 Cell-Cell Contact 0.3447 0.00000000000000213052656264166 Scatter Plot
Source MK Source CX3C CX3C Secreted Signaling 0.3496 0.0000000000000007955141779045712 Scatter Plot
Target MK Source LIFR LIFR Secreted Signaling 0.3543 0.0000000000000003071806432609104 Scatter Plot
Source MK Source IGF IGF Secreted Signaling 0.3824 0.0000000000000000007339155228641361 Scatter Plot
Target MK Target KIT KIT Secreted Signaling 0.3826 0.0000000000000000007078445589027122 Scatter Plot
Target MK Source ANGPT ANGPT Secreted Signaling 0.3867 0.00000000000000000027425927147589585 Scatter Plot
Target MK Source MHC-I MHC-I Cell-Cell Contact 0.4043 0.00000000000000000000435448059064357 Scatter Plot
Source MK Source PDGF PDGF Secreted Signaling 0.4178 0.00000000000000000000014957562756001172 Scatter Plot
Target MK Target WNT WNT Secreted Signaling 0.4192 0.00000000000000000000010643545807103266 Scatter Plot
Source MK Source PSAP PSAP Secreted Signaling 0.4225 0.00000000000000000000004512970751974704 Scatter Plot
Target MK Target VWF VWF ECM-Receptor 0.4230 0.000000000000000000000039978312423025536 Scatter Plot
Source MK Source PROS PROS Secreted Signaling 0.4239 0.000000000000000000000031860242070091495 Scatter Plot
Source MK Source CDH CDH Cell-Cell Contact 0.4262 0.000000000000000000000017447732144516638 Scatter Plot
Target MK Source GALECTIN GALECTIN Secreted Signaling 0.4659 0.00000000000000000000000000025588565286205788 Scatter Plot
Source MK Source IL7 IL7 Secreted Signaling 0.4810 0.000000000000000000000000000002507646107235143 Scatter Plot
Source MK Source TWEAK TWEAK Secreted Signaling 0.4886 0.00000000000000000000000000000022828006567332077 Scatter Plot
Source MK Source BMP BMP Secreted Signaling 0.5000 0.000000000000000000000000000000005474153111131704 Scatter Plot
Source MK Source ANGPT ANGPT Secreted Signaling 0.5195 0.000000000000000000000000000000000006523467269600745 Scatter Plot
Source MK Source ESAM ESAM Cell-Cell Contact 0.5279 0.00000000000000000000000000000000000031190945095175785 Scatter Plot
Source MK Source GAS GAS Secreted Signaling 0.5279 0.000000000000000000000000000000000000311813007573849 Scatter Plot
Source MK Source JAM JAM Cell-Cell Contact 0.5342 0.00000000000000000000000000000000000003034257820538919 Scatter Plot
Source MK Source MHC-I MHC-I Cell-Cell Contact 0.5533 0.000000000000000000000000000000000000000018541823291617743 Scatter Plot
Source MK Source MHC-II MHC-II Cell-Cell Contact 0.5855 0.000000000000000000000000000000000000000000000023625919279012357 Scatter Plot
Target MK Source VISTA VISTA Cell-Cell Contact -0.5847 0.00000000000000000000000000000000000000000000003291960295931786 Scatter Plot
Target MK Source ANNEXIN ANNEXIN Secreted Signaling -0.5788 0.000000000000000000000000000000000000000000000459298454597101 Scatter Plot
Target MK Source SELL SELL Cell-Cell Contact -0.5369 0.000000000000000000000000000000000000010715637149073203 Scatter Plot
Target MK Source COMPLEMENT COMPLEMENT Secreted Signaling -0.5304 0.00000000000000000000000000000000000012343846587314848 Scatter Plot
Target MK Source CD52 CD52 Cell-Cell Contact -0.5155 0.000000000000000000000000000000000026978206744251263 Scatter Plot
Target MK Source SEMA4 SEMA4 Cell-Cell Contact -0.4655 0.00000000000000000000000000029159935821447677 Scatter Plot
Target MK Source APP APP Cell-Cell Contact -0.4550 0.000000000000000000000000006362798710356688 Scatter Plot
Target MK Source PARs PARs Secreted Signaling -0.3863 0.00000000000000000030042999808786414 Scatter Plot
Target MK Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.3852 0.0000000000000000003936820952158925 Scatter Plot
Source MK Source TGFb TGFb Secreted Signaling -0.3638 0.00000000000000004299738213433897 Scatter Plot
Target MK Source GRN GRN Secreted Signaling -0.3600 0.00000000000000009610631002331836 Scatter Plot
Target MK Source CCL CCL Secreted Signaling -0.3532 0.00000000000000038897156785593113 Scatter Plot
Target MK Source SPP1 SPP1 Secreted Signaling -0.3371 0.000000000000009423749974024072 Scatter Plot
Source MK Source ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact -0.3303 0.000000000000034391299574208084 Scatter Plot
Source MK Source SELL SELL Cell-Cell Contact -0.3275 0.00000000000005725023146901143 Scatter Plot
Target MK Source LAIR1 LAIR1 Cell-Cell Contact -0.3209 0.00000000000019385384521154466 Scatter Plot
Target MK Source NCAM NCAM Cell-Cell Contact -0.3102 0.0000000000012829919114753434 Scatter Plot
Target MK Source TNF TNF Secreted Signaling -0.2938 0.000000000020540665483659216 Scatter Plot
Target MK Source BAFF BAFF Secreted Signaling -0.2787 0.00000000022580777327794568 Scatter Plot
Source MK Source SEMA4 SEMA4 Cell-Cell Contact -0.2628 0.000000002432431045898389 Scatter Plot
Source MK Source PARs PARs Secreted Signaling -0.2582 0.000000004657589451045441 Scatter Plot
Target MK Target SEMA3 SEMA3 Secreted Signaling -0.2484 0.000000018176996208494235 Scatter Plot
Target MK Source CLEC CLEC Cell-Cell Contact -0.2409 0.00000004915792962226648 Scatter Plot
Source MK Source MIF MIF Secreted Signaling -0.2402 0.000000054139133834783956 Scatter Plot
Target MK Target NCAM NCAM Cell-Cell Contact -0.2040 0.000004231804624091048 Scatter Plot
Target MK Target IL17 IL17 Secreted Signaling -0.1643 0.0002245669607511 Scatter Plot
Source MK Source VISTA VISTA Cell-Cell Contact -0.1515 0.0006777277352855 Scatter Plot
Source MK Source SPP1 SPP1 Secreted Signaling -0.1470 0.0009797372136835 Scatter Plot
Source MK Source NCAM NCAM Cell-Cell Contact -0.1460 0.0010640372254408 Scatter Plot
Target MK Source NKG2D NKG2D Cell-Cell Contact -0.1443 0.0012166083712385 Scatter Plot
Target MK Source IL16 IL16 Secreted Signaling -0.1314 0.0032334943008384 Scatter Plot
Target MK Target SELE SELE Cell-Cell Contact -0.1096 0.0141964212081632 Scatter Plot
Source MK Source TNF TNF Secreted Signaling -0.1090 0.01475356402005 Scatter Plot
Target MK Source ICOS ICOS Cell-Cell Contact -0.0971 0.0298964030433793 Scatter Plot
Source MK Source SEMA6 SEMA6 Cell-Cell Contact 0.0995 0.0260255347519426 Scatter Plot
Target MK Target SELL SELL Cell-Cell Contact 0.1012 0.0236437126010189 Scatter Plot
Source MK Source FN1 FN1 ECM-Receptor 0.1046 0.0193493552071018 Scatter Plot
Source MK Target LAIR1 LAIR1 Cell-Cell Contact 0.1062 0.0175463467041097 Scatter Plot
Source MK Target BST2 BST2 Cell-Cell Contact 0.1062 0.0175463467041097 Scatter Plot
Target MK Target NOTCH NOTCH Cell-Cell Contact 0.1064 0.0173656666752086 Scatter Plot
Target MK Target PDGF PDGF Secreted Signaling 0.1093 0.0144825830783719 Scatter Plot
Source MK Source ICOS ICOS Cell-Cell Contact 0.1120 0.0122160786210477 Scatter Plot
Target MK Target CADM CADM Cell-Cell Contact 0.1134 0.0111337986274767 Scatter Plot
Source MK Target GAS GAS Secreted Signaling 0.1175 0.0085217126389117 Scatter Plot
Source MK Target GALECTIN GALECTIN Secreted Signaling 0.1176 0.0085012231590005 Scatter Plot
Target MK Target COMPLEMENT COMPLEMENT Secreted Signaling 0.1200 0.0072128681408017 Scatter Plot
Target MK Target OSM OSM Secreted Signaling 0.1241 0.0054476226853938 Scatter Plot
Target MK Target NODAL NODAL Secreted Signaling 0.1254 0.004971500658781 Scatter Plot
Target MK Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.1259 0.0048197243323882 Scatter Plot
Source MK Target CADM CADM Cell-Cell Contact 0.1312 0.0032824664805992 Scatter Plot
Source MK Target RANKL RANKL Secreted Signaling 0.1324 0.0030055537032178 Scatter Plot
Source MK Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.1331 0.0028686021564598 Scatter Plot
Target MK Target TWEAK TWEAK Secreted Signaling 0.1388 0.0018708728446045 Scatter Plot
Source MK Target NODAL NODAL Secreted Signaling 0.1419 0.0014702602615468 Scatter Plot
Source MK Target PTN PTN Secreted Signaling 0.1429 0.0013597043560959 Scatter Plot
Target MK Target CD200 CD200 Cell-Cell Contact 0.1478 0.0009164069944326 Scatter Plot
Source MK Source PTN PTN Secreted Signaling 0.1504 0.000738770550723 Scatter Plot
Source MK Target VEGF VEGF Secreted Signaling 0.1529 0.0006045712328657 Scatter Plot
Source MK Target AGT AGT Secreted Signaling 0.1532 0.0005868936717536 Scatter Plot
Source MK Source ANGPTL ANGPTL Secreted Signaling 0.1539 0.0005528114306816 Scatter Plot
Source MK Target COLLAGEN COLLAGEN ECM-Receptor 0.1577 0.000401151346202 Scatter Plot
Source MK Target SEMA3 SEMA3 Secreted Signaling 0.1587 0.0003670322841152 Scatter Plot
Target MK Target RANKL RANKL Secreted Signaling 0.1644 0.0002223716259976 Scatter Plot
Target MK Target BAFF BAFF Secreted Signaling 0.1650 0.0002115005066285 Scatter Plot
Source MK Target EPHA EPHA Cell-Cell Contact 0.1665 0.0001833043760093 Scatter Plot
Source MK Target SEMA6 SEMA6 Cell-Cell Contact 0.1773 0.00006728804952757174 Scatter Plot
Source MK Target NCAM NCAM Cell-Cell Contact 0.1809 0.00004720334162175405 Scatter Plot
Target MK Target AGT AGT Secreted Signaling 0.1852 0.000031006601193748404 Scatter Plot
Target MK Target MIF MIF Secreted Signaling 0.1869 0.000026032171984770623 Scatter Plot
Source MK Target FN1 FN1 ECM-Receptor 0.1939 0.000012565559326480018 Scatter Plot
Source MK Target THY1 THY1 Cell-Cell Contact 0.1960 0.000010108709038703724 Scatter Plot
Source MK Source CD1D2 CD1D2 Cell-Cell Contact 0.2059 0.0000034393108475238254 Scatter Plot
Source MK Source THY1 THY1 Cell-Cell Contact 0.2107 0.000001991638021779404 Scatter Plot
Target MK Target APP APP Cell-Cell Contact 0.2122 0.0000016902242471479202 Scatter Plot
Source MK Target GDF GDF Secreted Signaling 0.2131 0.0000015228271255509626 Scatter Plot
Source MK Target CD23 CD23 Cell-Cell Contact 0.2173 0.0000009286394247010784 Scatter Plot
Source MK Target CSPG4 CSPG4 Cell-Cell Contact 0.2194 0.0000007261921522736894 Scatter Plot
Source MK Target SEMA5 SEMA5 Cell-Cell Contact 0.2237 0.0000004314230101306273 Scatter Plot
Source MK Target IL6 IL6 Secreted Signaling 0.2327 0.00000014183487956267468 Scatter Plot
Target MK Target PERIOSTIN PERIOSTIN Secreted Signaling 0.2407 0.00000005075241459867367 Scatter Plot
Target MK Target CDH CDH Cell-Cell Contact 0.2414 0.00000004609818837467959 Scatter Plot
Target MK Target NPR2 NPR2 Secreted Signaling 0.2437 0.000000034043779978499584 Scatter Plot
Source MK Source IL2 IL2 Secreted Signaling 0.2451 0.00000002828452222528661 Scatter Plot
Source MK Source CCL CCL Secreted Signaling 0.2490 0.000000016646602646235746 Scatter Plot
Target MK Target SEMA6 SEMA6 Cell-Cell Contact 0.2544 0.000000007893925255765149 Scatter Plot
Target MK Target BSP BSP ECM-Receptor 0.2548 0.000000007487201657393225 Scatter Plot
Target MK Target ITGAL-ITGB2 ITGAL-ITGB2 Cell-Cell Contact 0.2575 0.000000005169084661640048 Scatter Plot
Target MK Target SEMA5 SEMA5 Cell-Cell Contact 0.2671 0.0000000013001536154785999 Scatter Plot
Source MK Target THBS THBS ECM-Receptor 0.2675 0.000000001225503745159607 Scatter Plot
Source MK Target SPP1 SPP1 Secreted Signaling 0.2690 0.000000000975707784796016 Scatter Plot
Source MK Target LAMININ LAMININ ECM-Receptor 0.2705 0.0000000007871820540841102 Scatter Plot
Source MK Target ACTIVIN ACTIVIN Secreted Signaling 0.2754 0.00000000037544095342224967 Scatter Plot
Target MK Target DMP1 DMP1 ECM-Receptor 0.2771 0.000000000289088183844677 Scatter Plot
Source MK Target SEMA7 SEMA7 Cell-Cell Contact 0.2827 0.00000000012080660738348177 Scatter Plot
Target MK Target FGF FGF Secreted Signaling 0.2853 0.00000000008018799759076367 Scatter Plot
Target MK Target SEMA4 SEMA4 Cell-Cell Contact 0.2861 0.00000000007080844792872939 Scatter Plot
Target MK Target NRG NRG Secreted Signaling 0.2928 0.0000000000241051914108888 Scatter Plot
Source MK Source ICAM ICAM Cell-Cell Contact 0.2946 0.000000000018192348328339294 Scatter Plot
Source MK Target PARs PARs Secreted Signaling 0.2959 0.000000000014674343787167637 Scatter Plot
Source MK Target ADIPONECTIN ADIPONECTIN Secreted Signaling 0.2959 0.00000000001461963355084719 Scatter Plot
Source MK Target COMPLEMENT COMPLEMENT Secreted Signaling 0.2987 0.000000000009190404898564566 Scatter Plot
Source MK Target VISFATIN VISFATIN Secreted Signaling 0.3010 0.000000000006228624556167611 Scatter Plot
Source MK Target EPHB EPHB Cell-Cell Contact 0.3069 0.000000000002285553555047778 Scatter Plot
Source MK Source NOTCH NOTCH Cell-Cell Contact 0.3093 0.000000000001510625342751272 Scatter Plot
Source MK Target KIT KIT Secreted Signaling 0.3140 0.0000000000006700788427399628 Scatter Plot
Source MK Source LCK LCK Cell-Cell Contact 0.3151 0.0000000000005445459069830627 Scatter Plot
Source MK Target ANGPTL ANGPTL Secreted Signaling 0.3188 0.0000000000002812042844318242 Scatter Plot
Target MK Target ESAM ESAM Cell-Cell Contact 0.3214 0.00000000000017657753818759268 Scatter Plot
Source MK Source IL16 IL16 Secreted Signaling 0.3237 0.00000000000011578850997350281 Scatter Plot
Source MK Target OSM OSM Secreted Signaling 0.3289 0.000000000000044230518634442594 Scatter Plot
Source MK Target TGFb TGFb Secreted Signaling 0.3380 0.000000000000007929902884026527 Scatter Plot
Source MK Target CD22 CD22 Cell-Cell Contact 0.3403 0.000000000000005074414402100291 Scatter Plot
Source MK Source CD45 CD45 Cell-Cell Contact 0.3403 0.000000000000005074414402100237 Scatter Plot
Source MK Source EPHB EPHB Cell-Cell Contact 0.3420 0.000000000000003654152256009601 Scatter Plot
Source MK Source CSF CSF Secreted Signaling 0.3552 0.0000000000000002593220258871393 Scatter Plot
Source MK Target VWF VWF ECM-Receptor 0.3573 0.00000000000000016663815144046075 Scatter Plot
Source MK Target SEMA4 SEMA4 Cell-Cell Contact 0.3628 0.000000000000000053143620682678435 Scatter Plot
Source MK Target BAFF BAFF Secreted Signaling 0.3672 0.000000000000000020919687558571958 Scatter Plot
Source MK Target VTN VTN ECM-Receptor 0.3746 0.00000000000000000418540865193708 Scatter Plot
Target MK Target CD34 CD34 Cell-Cell Contact 0.3748 0.000000000000000004014696263149782 Scatter Plot
Source MK Source FLT3 FLT3 Secreted Signaling 0.3790 0.0000000000000000015789333620744513 Scatter Plot
Source MK Target ANGPT ANGPT Secreted Signaling 0.3792 0.0000000000000000015247413239133942 Scatter Plot
Source MK Target NPR2 NPR2 Secreted Signaling 0.3795 0.0000000000000000014229366260839825 Scatter Plot
Source MK Target BMP BMP Secreted Signaling 0.3809 0.0000000000000000010406713765360382 Scatter Plot
Target MK Target ncWNT ncWNT Secreted Signaling 0.3902 0.0000000000000000001232167918899304 Scatter Plot
Source MK Source CD86 CD86 Cell-Cell Contact 0.4008 0.000000000000000000010072360871227996 Scatter Plot
Source MK Target FGF FGF Secreted Signaling 0.4117 0.0000000000000000000007103646252496777 Scatter Plot
Source MK Target CD200 CD200 Cell-Cell Contact 0.4122 0.0000000000000000000006179276643673856 Scatter Plot
Source MK Target PERIOSTIN PERIOSTIN Secreted Signaling 0.4228 0.00000000000000000000004238859293043258 Scatter Plot
Source MK Target CDH CDH Cell-Cell Contact 0.4262 0.000000000000000000000017447732144516638 Scatter Plot
Source MK Target IGF IGF Secreted Signaling 0.4293 0.00000000000000000000000774349696077047 Scatter Plot
Source MK Target TENASCIN TENASCIN ECM-Receptor 0.4315 0.00000000000000000000000422257090171105 Scatter Plot
Source MK Target NRG NRG Secreted Signaling 0.4340 0.0000000000000000000000021862816153607797 Scatter Plot
Source MK Target DMP1 DMP1 ECM-Receptor 0.4361 0.0000000000000000000000012316064723115171 Scatter Plot
Source MK Target BSP BSP ECM-Receptor 0.4394 0.000000000000000000000000502777801233526 Scatter Plot
Source MK Source BST2 BST2 Cell-Cell Contact 0.4431 0.00000000000000000000000018237030818062597 Scatter Plot
Source MK Source COLLAGEN COLLAGEN ECM-Receptor 0.4431 0.00000000000000000000000018200716018328367 Scatter Plot
Source MK Source SEMA7 SEMA7 Cell-Cell Contact 0.4507 0.00000000000000000000000002165220712977032 Scatter Plot
Source MK Target CD39 CD39 Cell-Cell Contact 0.4603 0.0000000000000000000000000013651846288737169 Scatter Plot
Source MK Target APP APP Cell-Cell Contact 0.4750 0.000000000000000000000000000016601151080164618 Scatter Plot
Source MK Target ncWNT ncWNT Secreted Signaling 0.4771 0.000000000000000000000000000008627183658198091 Scatter Plot
Source MK Target CD34 CD34 Cell-Cell Contact 0.4773 0.000000000000000000000000000007968298109229389 Scatter Plot
Source MK Target SLURP SLURP Secreted Signaling 0.4836 0.0000000000000000000000000000011067938537412774 Scatter Plot
Source MK Target WNT WNT Secreted Signaling 0.4886 0.0000000000000000000000000000002279874400410385 Scatter Plot
Source MK Target JAM JAM Cell-Cell Contact 0.4949 0.00000000000000000000000000000002918033328768296 Scatter Plot
Target MK Target PARs PARs Secreted Signaling 0.5150 0.000000000000000000000000000000000031231452579941563 Scatter Plot
Source MK Target MIF MIF Secreted Signaling 0.5272 0.000000000000000000000000000000000000395828573503582 Scatter Plot
Source MK Target ESAM ESAM Cell-Cell Contact 0.5279 0.00000000000000000000000000000000000031190945095175785 Scatter Plot
Source MK Source MHC-I MHC-I Cell-Cell Contact 0.5565 0.0000000000000000000000000000000000000000052133462436956726 Scatter Plot
Source MK Source MHC-II MHC-II Cell-Cell Contact 0.5855 0.000000000000000000000000000000000000000000000023625919279012357 Scatter Plot
Target MK Target CD52 CD52 Cell-Cell Contact -0.4833 0.0000000000000000000000000000012373268677917267 Scatter Plot
Target MK Target IFN-II IFN-II Secreted Signaling -0.4506 0.00000000000000000000000002254136210876116 Scatter Plot
Source MK Source CD52 CD52 Cell-Cell Contact -0.4350 0.0000000000000000000000016713998431099078 Scatter Plot
Target MK Target ICAM ICAM Cell-Cell Contact -0.4325 0.000000000000000000000003236836975450003 Scatter Plot
Target MK Target CEACAM CEACAM Cell-Cell Contact -0.4180 0.0000000000000000000001435114945989773 Scatter Plot
Target MK Target CCL CCL Secreted Signaling -0.3965 0.000000000000000000028075976886340333 Scatter Plot
Target MK Target VCAM VCAM Cell-Cell Contact -0.3928 0.00000000000000000006815402276221431 Scatter Plot
Target MK Target CLEC CLEC Cell-Cell Contact -0.3770 0.0000000000000000024609593395814467 Scatter Plot
Target MK Target CXCL CXCL Secreted Signaling -0.3671 0.000000000000000021263176905834466 Scatter Plot
Target MK Target COMPLEMENT COMPLEMENT Secreted Signaling -0.3418 0.000000000000003740400374326078 Scatter Plot
Source MK Target ICAM ICAM Cell-Cell Contact -0.3211 0.00000000000018582413074104398 Scatter Plot
Target MK Target CSF CSF Secreted Signaling -0.2940 0.000000000019985474381512997 Scatter Plot
Source MK Source COMPLEMENT COMPLEMENT Secreted Signaling -0.2921 0.00000000002712392572064516 Scatter Plot
Source MK Target CD52 CD52 Cell-Cell Contact -0.2880 0.000000000052161443426944695 Scatter Plot
Target MK Target ANNEXIN ANNEXIN Secreted Signaling -0.2651 0.0000000017255302996627207 Scatter Plot
Target MK Target SELPLG SELPLG Cell-Cell Contact -0.2407 0.00000005078160232398536 Scatter Plot
Source MK Source MIF MIF Secreted Signaling -0.2402 0.000000054139133834785564 Scatter Plot
Target MK Target IL1 IL1 Secreted Signaling -0.2289 0.00000022827004078858826 Scatter Plot
Target MK Target VEGF VEGF Secreted Signaling -0.2271 0.0000002847059845885805 Scatter Plot
Source MK Source ANGPTL ANGPTL Secreted Signaling -0.2109 0.000001961788070419335 Scatter Plot
Source MK Source CLEC CLEC Cell-Cell Contact -0.2064 0.000003252383247526322 Scatter Plot
Source MK Target CEACAM CEACAM Cell-Cell Contact -0.2037 0.000004402448088371797 Scatter Plot
Target MK Target GALECTIN GALECTIN Secreted Signaling -0.1811 0.00004617334077417797 Scatter Plot
Source MK Target CSF CSF Secreted Signaling -0.1802 0.00005067588807740723 Scatter Plot
Target MK Target THY1 THY1 Cell-Cell Contact -0.1782 0.00006148993409084243 Scatter Plot
Target MK Target CD23 CD23 Cell-Cell Contact -0.1689 0.0001475337045561 Scatter Plot
Target MK Target GRN GRN Secreted Signaling -0.1669 0.0001768373995992 Scatter Plot
Source MK Target COLLAGEN COLLAGEN ECM-Receptor -0.1509 0.0007139499976223 Scatter Plot
Source MK Target CCL CCL Secreted Signaling -0.1501 0.0007593083617992 Scatter Plot
Source MK Target CXCL CXCL Secreted Signaling -0.1500 0.0007682693048921 Scatter Plot
Source MK Target CLEC CLEC Cell-Cell Contact -0.1453 0.0011204946850749 Scatter Plot
Source MK Target VCAM VCAM Cell-Cell Contact -0.1442 0.0012255863084584 Scatter Plot
Source MK Target IL17 IL17 Secreted Signaling -0.1292 0.0038038818402386 Scatter Plot
Source MK Target IFN-II IFN-II Secreted Signaling -0.1193 0.0075849737910033 Scatter Plot
Source MK Source IL1 IL1 Secreted Signaling -0.1183 0.0081018504848414 Scatter Plot
Source MK Source LAIR1 LAIR1 Cell-Cell Contact -0.1004 0.0247011358205368 Scatter Plot
Source MK Source FGF FGF Secreted Signaling -0.0997 0.0257440793937936 Scatter Plot
Source MK Source CCL CCL Secreted Signaling -0.0991 0.0266385695763142 Scatter Plot

Cells that are targets of MK from HSCs*

Cells that are source of MK to HSCs*

Ligands:

Receptors:

*Cell types are filtered such that they interact with at least 5% of HSCs.